CisView: Mouse (mm6, March2005)

Transcription factor binding site ADD_FXRDR3

Source: Laffitte BA, Kast HR, Nguyen CM, Zavacki AM, Moore DD, Edwards PA. 2000. Identification of the DNA binding specificity and potential target genes for the farnesoid X-activated receptor. J Biol Chem. 275:10638-47.
TF group: FXR       TFBS class: HR = Hormone receptor       Code: 2.1.2.8.4
Pattern = AGSTCANNNAGGTCT (used as matrix, core elements are bold)     Class: FXR     Allowed mismatch: 0.2     Palindrome
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Genes (trans-elements):
U-clusterSymbol
Annotation
U032117Nr1h4nuclear receptor subfamily 1, group H, member 4

GO terms:
GO:0003707 steroid hormone receptor activity
GO:0004872 receptor activity
GO:0004879 ligand-dependent nuclear receptor activity
GO:0008206 bile acid metabolism

Protein domains:
IPR001723 Steroid hormone receptor
IPR000536 Ligand-binding region of nuclear hormone receptor
IPR001093 IMP dehydrogenase/GMP reductase
IPR008946 Steroid nuclear receptor, ligand-binding
IPR001628 Zn-finger, C4-type steroid receptor
IPR000324 Vitamin D receptor

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend