TFBS = ADD

CisView: Mouse (mm6, March2005)

Transcription factor binding site ADD_LRH

Source: Gu P, Goodwin B, Chung AC, Xu X, Wheeler DA, Price RR, Galardi C, Peng L, Latour AM, Koller BH, Gossen J, Kliewer SA, Cooney AJ. 2005. Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic development. Mol Cell Biol. 25(9):3492-3505.
TF group: SF1 TFBS class: HR = Hormone receptor Code: 2.1.4
Pattern = TCAAGGYYA (core elements are bold) Class: SF1 Allowed mismatch: 0.048
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Position weight matrix:

position A C G T
1 1 5 1 11
2 0 18 0 0
3 18 0 0 0
4 18 0 0 0
5 0 0 18 0
6 0 0 17 1
7 2 7 3 6
8 0 11 0 7
9 10 3 5 0

Genes (trans-elements):

U-cluster Symbol Annotation
U021824 Nr5a2 nuclear receptor subfamily 5, group A, member 2

GO terms:
GO:0042632 cholesterol homeostasis
GO:0004872 receptor activity
GO:0004879 ligand-dependent nuclear receptor activity
GO:0003707 steroid hormone receptor activity
GO:0008206 bile acid metabolism

Protein domains:
IPR001723 Steroid hormone receptor
IPR000536 Ligand-binding region of nuclear hormone receptor
IPR001093 IMP dehydrogenase/GMP reductase
IPR008946 Steroid nuclear receptor, ligand-binding
IPR001628 Zn-finger, C4-type steroid receptor
IPR000324 Vitamin D receptor

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

position	A	C	G	T
1	1	5	1	11
2	0	18	0	0
3	18	0	0	0
4	18	0	0	0
5	0	0	18	0
6	0	0	17	1
7	2	7	3	6
8	0	11	0	7
9	10	3	5	0

U-cluster	Symbol	Annotation
U021824	Nr5a2	nuclear receptor subfamily 5, group A, member 2

Legend