CisView: Mouse (mm6, March2005)
Transcription factor binding site ADD_LXR1

Source: Joseph SB, Laffitte BA, Patel PH, Watson MA, Matsukuma KE, Walczak R, Collins JL, Osborne TF, Tontonoz P. 2002. Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors. J Biol Chem. 277:11019-25.
TF group: LXR       TFBS class: HR = Hormone receptor       Code: 2.1.2
Pattern = RGGTTANNNNMGGTCA (used as matrix, core elements are bold)     Class: LXR     Allowed mismatch: 0.2
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Genes (trans-elements):
U-clusterSymbol
Annotation
U001539Rxraretinoid X receptor alpha
U013319Rararetinoic acid receptor, alpha
U022046Nr1i3nuclear receptor subfamily 1, group I, member 3
U023018Nr1h3nuclear receptor subfamily 1, group H, member 3
U023925Pex2peroxin 2
U027840Pex5peroxisome biogenesis factor 5
U035259Rarbretinoic acid receptor, beta
U036693Rargretinoic acid receptor, gamma
U043589Rxrbretinoid X receptor beta
U134659Nr1h2nuclear receptor subfamily 1, group H, member 2

GO terms:
GO:0004872 receptor activity
GO:0003707 steroid hormone receptor activity
GO:0004879 ligand-dependent nuclear receptor activity
GO:0003708 retinoic acid receptor activity
GO:0005496 steroid binding
GO:0004887 thyroid hormone receptor activity
GO:0044255 cellular lipid metabolism
GO:0001657 ureteric bud development
GO:0001764 neuron migration
GO:0015031 protein transport
GO:0016481 negative regulation of transcription
GO:0006820 anion transport
GO:0005489 electron transporter activity
GO:0004884 ecdysteroid hormone receptor activity
GO:0005777 peroxisome
GO:0005051 peroxisome targeting signal receptor activity
GO:0000004 biological process unknown
GO:0006625 protein-peroxisome targeting
GO:0005507 copper ion binding
GO:0005741 mitochondrial outer membrane
GO:0007031 peroxisome organization and biogenesis
GO:0006118 electron transport
GO:0008308 voltage-gated ion-selective channel activity

Protein domains:
IPR008946 Steroid nuclear receptor, ligand-binding
IPR001723 Steroid hormone receptor
IPR000536 Ligand-binding region of nuclear hormone receptor
IPR001093 IMP dehydrogenase/GMP reductase
IPR001628 Zn-finger, C4-type steroid receptor
IPR003078 Retinoic acid receptor
IPR000324 Vitamin D receptor
IPR001440 TPR repeat
IPR000003 Retinoid X receptor
IPR001728 Thyroid hormone receptor
IPR008940 Protein prenyltransferase
IPR001925 Porin, eukaryotic type
IPR003069 Ecdysteroid receptor
IPR000923 Blue (type 1) copper domain

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend