CisView: Mouse (mm6, March2005)
Transcription factor binding site ADD_LXR2

Source: Volle DH, Repa JJ, Mazur A, Cummins CL, Val P, Henry-Berger J, Caira F, Veyssiere G, Mangelsdorf DJ, Lobaccaro JM. 2004. Regulation of the aldo-keto reductase gene akr1b7 by the nuclear oxysterol receptor LXRalpha (liver X receptor-alpha) in the mouse intestine: putative role of LXRs in lipid detoxification processes. Mol Endocrinol. 18:888-98.
TF group: LXR       TFBS class: HR = Hormone receptor       Code: 2.1.2
Pattern = ANGTCANNNNMGWKSA (used as matrix, core elements are bold)     Class: LXR     Allowed mismatch: 0.156
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Genes (trans-elements):
U-clusterSymbol
Annotation
U001539Rxraretinoid X receptor alpha
U013319Rararetinoic acid receptor, alpha
U022046Nr1i3nuclear receptor subfamily 1, group I, member 3
U023018Nr1h3nuclear receptor subfamily 1, group H, member 3
U023925Pex2peroxin 2
U027840Pex5peroxisome biogenesis factor 5
U035259Rarbretinoic acid receptor, beta
U036693Rargretinoic acid receptor, gamma
U043589Rxrbretinoid X receptor beta
U134659Nr1h2nuclear receptor subfamily 1, group H, member 2

GO terms:
GO:0004872 receptor activity
GO:0003707 steroid hormone receptor activity
GO:0004879 ligand-dependent nuclear receptor activity
GO:0003708 retinoic acid receptor activity
GO:0005496 steroid binding
GO:0004887 thyroid hormone receptor activity
GO:0044255 cellular lipid metabolism
GO:0001657 ureteric bud development
GO:0001764 neuron migration
GO:0015031 protein transport
GO:0016481 negative regulation of transcription
GO:0006820 anion transport
GO:0005489 electron transporter activity
GO:0004884 ecdysteroid hormone receptor activity
GO:0005777 peroxisome
GO:0005051 peroxisome targeting signal receptor activity
GO:0000004 biological process unknown
GO:0006625 protein-peroxisome targeting
GO:0005507 copper ion binding
GO:0005741 mitochondrial outer membrane
GO:0007031 peroxisome organization and biogenesis
GO:0006118 electron transport
GO:0008308 voltage-gated ion-selective channel activity

Protein domains:
IPR008946 Steroid nuclear receptor, ligand-binding
IPR001723 Steroid hormone receptor
IPR000536 Ligand-binding region of nuclear hormone receptor
IPR001093 IMP dehydrogenase/GMP reductase
IPR001628 Zn-finger, C4-type steroid receptor
IPR003078 Retinoic acid receptor
IPR000324 Vitamin D receptor
IPR001440 TPR repeat
IPR000003 Retinoid X receptor
IPR001728 Thyroid hormone receptor
IPR008940 Protein prenyltransferase
IPR001925 Porin, eukaryotic type
IPR003069 Ecdysteroid receptor
IPR000923 Blue (type 1) copper domain

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend