CisView: Mouse (mm6, March2005)
Transcription factor binding site ADD_SOX

Source: Yuan H, Corbi N, Basilico C, Dailey L. 1995. Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox-2 and Oct-3. Genes & Dev. 9: 2635-2645.
TF group: SOX       TFBS class: HMG = High mobility group       Code: 4.7.1.0
Pattern = TCTTTGTT     Class: SOX     Allowed mismatch: 0.2
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Genes (trans-elements):
U-clusterSymbol
Annotation
U003145Sox2SRY-box containing gene 2
U012826Sox15SRY-box containing gene 15
U013510Sox9SRY-box containing gene 9
U015966Sox21SRY-box containing gene 21
U021771Sox13SRY-box containing gene 13
U023502Sox12SRY-box containing gene 12
U023794Sox18SRY-box containing gene 18
U028015Sox5SRY-box containing gene 5
U029157Sox6SRY-box containing gene 6
U031238Sox14SRY-box containing gene 14
U036399Sox10SRY-box containing gene 10
U037556Sox8SRY-box containing gene 8
U039416Sox3SRY-box containing gene 3
U072950Sox4SRY-box containing gene 4
U232573Sox11Mus musculus SRY-box containing gene 11 (Sox11), mRNA
U302716Srysex determining region of Chr Y

GO terms:
GO:0000785 chromatin
GO:0051216 cartilage development
GO:0045165 cell fate commitment
GO:0001708 cell fate specification
GO:0030154 cell differentiation
GO:0019100 male germ-line sex determination
GO:0003705 RNA polymerase II transcription factor activity, enhancer binding
GO:0007507 heart development
GO:0009887 organogenesis
GO:0006325 establishment and/or maintenance of chromatin architecture
GO:0030900 forebrain development
GO:0035051 cardiac cell differentiation
GO:0008584 male gonad development
GO:0001837 epithelial to mesenchymal transition
GO:0003682 chromatin binding
GO:0001502 cartilage condensation
GO:0042692 muscle cell differentiation

Protein domains:
IPR000910 HMG1/2 (high mobility group) box
IPR009071 High mobility group box
IPR001093 IMP dehydrogenase/GMP reductase
IPR000135 High mobility group proteins HMG1 and HMG2
IPR010978 tRNA-binding arm
IPR010916 TonB box, N-terminal

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

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