TFBS = ADD

CisView: Mouse (mm6, March2005)

Transcription factor binding site ADD_TBX5

Source: Ghosh TK, Packham EA, Bonser AJ, Robinson TE, Cross SJ, Brook JD. 2001. Characterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndrome. Hum Mol Genet. 10:1983-94.
TF group: TBX5 TFBS class: T-box
Pattern = AGGTGTBA (core elements are bold) Class: TBX5 Allowed mismatch: 0.029
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Position weight matrix:

position A C G T
1 41 1 12 2
2 0 0 56 1
3 0 0 55 3
4 0 0 0 58
5 0 0 54 0
6 1 6 0 47
7 1 15 17 19
8 30 4 13 3

Genes (trans-elements):

U-cluster Symbol Annotation
U006099 Tbx5 T-box 5

GO terms:
GO:0002009 morphogenesis of an epithelium
GO:0007275 development
GO:0007507 heart development
GO:0007389 pattern specification
GO:0030324 lung development
GO:0030326 embryonic limb morphogenesis

Protein domains:
IPR001699 Transcription factor, T-box
IPR008967 p53-like transcription factor, DNA-binding
IPR002070 Transcription factor, Brachyury

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

position	A	C	G	T
1	41	1	12	2
2	0	0	56	1
3	0	0	55	3
4	0	0	0	58
5	0	0	54	0
6	1	6	0	47
7	1	15	17	19
8	30	4	13	3

Legend