CisView: Mouse (mm6, March2005)
Transcription factor binding site MIT_005NFY

Source: Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Kellis M. 2005. Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature 434(7031):338-345.
TF group: NFY       TFBS class: histone fold       Code: 4.8.1.0
Pattern = GATTGGY     Class: NFY     Allowed mismatch: 0.2
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Genes (trans-elements):
U-clusterSymbol
Annotation
U037830Runx2runt related transcription factor 2
U009738Cbfbcore binding factor beta
U009738Cbfbcore binding factor beta
U042412Cpceruloplasmin
U037898Nfyanuclear transcription factor-Y alpha
U032063Nfybnuclear transcription factor-Y beta
U025480Nfycnuclear transcription factor-Y gamma

GO terms:
GO:0001649 osteoblast differentiation
GO:0001503 ossification
GO:0030099 myeloid cell differentiation
GO:0003713 transcription coactivator activity
GO:0030098 lymphocyte differentiation
GO:0016491 oxidoreductase activity
GO:0006825 copper ion transport
GO:0004322 ferroxidase activity
GO:0006826 iron ion transport
GO:0042487 regulation of odontogenesis (sensu Vertebrata)
GO:0005507 copper ion binding
GO:0005524 ATP binding
GO:0006811 ion transport
GO:0001501 skeletal development
GO:0016563 transcriptional activator activity
GO:0003682 chromatin binding
GO:0042475 odontogenesis (sensu Vertebrata)
GO:0005375 copper ion transporter activity
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway

Protein domains:
IPR001093 IMP dehydrogenase/GMP reductase
IPR003958 Transcription factor CBF/NF-Y/archaeal histone
IPR009072 Histone-fold
IPR007124 Histone-fold/TFIID-TAF/NF-Y
IPR003417 Core binding factor, beta subunit
IPR003956 Histone-like transcription factor CBF/NF-Y/archaeal histone, subunit A
IPR001289 CCAAT-binding transcription factor, subunit B
IPR001117 Multicopper oxidase, type 1
IPR000040 Acute myeloid leukemia 1 protein (AML 1)/Runt
IPR003957 Histone-like transcription factor/archaeal histone/topoisomerase
IPR008967 p53-like transcription factor, DNA-binding
IPR008972 Cupredoxin
IPR011706 Multicopper oxidase, type 2
IPR008997 Ricin B-related lectin
IPR002355 Multicopper oxidase, copper-binding site

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend