CisView: Mouse (mm6, March2005)
Transcription factor binding site MIT_017IRF

Source: Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Kellis M. 2005. Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature 434(7031):338-345.
TF group: IRF       TFBS class: MYB/ETS = Tryptophan clusters       Code: 3.5.3.0
Pattern = AACTTT     Class: IRF     Allowed mismatch: 0.2     Palindrome
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Genes (trans-elements):
U-clusterSymbol
Annotation
U012603Irf1interferon regulatory factor 1
U321621Irf4interferon regulatory factor 4
U009319Irf2interferon regulatory factor 2
U008060Irf3interferon regulatory factor 3
U006617Irf5interferon regulatory factor 5
U029451Irf7interferon regulatory factor 7
U009890Icsbp1interferon consensus sequence binding protein 1

GO terms:
GO:0006955 immune response
GO:0042803 protein homodimerization activity
GO:0030099 myeloid cell differentiation
GO:0045084 positive regulation of interleukin-12 biosynthesis

Protein domains:
IPR001346 Interferon regulatory factor
IPR008984 SMAD/FHA

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend