CisView: Mouse (mm6, March2005)
Transcription factor binding site MIT_018SREBP

Source: Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Kellis M. 2005. Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature 434(7031):338-345.
TF group: SREBP       TFBS class: bHLH = Helix-loop-helix       Code: 1.3.1.3
Pattern = TCANNTGAY     Class: SREBP     Allowed mismatch: 0.2     Palindrome
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Genes (trans-elements):
U-clusterSymbol
Annotation
U032863Srebf1sterol regulatory element binding factor 1
U043465Srebf2sterol regulatory element binding factor 2

GO terms:
GO:0006629 lipid metabolism
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0008203 cholesterol metabolism
GO:0008202 steroid metabolism

Protein domains:
IPR001092 Basic helix-loop-helix dimerisation region bHLH
IPR001093 IMP dehydrogenase/GMP reductase
IPR011598 Helix-loop-helix DNA-binding
IPR003006 Immunoglobulin/major histocompatibility complex

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend