CisView: Mouse (mm6, March2005)

Transcription factor binding site MIT_035MYOD

Source: Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Kellis M. 2005. Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature 434(7031):338-345.
TF group: MYOD       TFBS class: bHLH = Helix-loop-helix       Code: 1.2
Pattern = GCANCTGNY     Class: MYOD     Allowed mismatch: 0.2
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Genes (trans-elements):
U-clusterSymbol
Annotation
U032010Tcfe2atranscription factor E2a
U031072Tcf12transcription factor 12
U037643Tff3trefoil factor 3, intestinal
U173038Tcf4transcription factor 4
U042448Mef2dmyocyte enhancer factor 2D
U031895Arid5bAT rich interactive domain 5B (Mrf1 like)
U032203Myf6myogenic factor 6
U008102Myod1myogenic differentiation 1
U032203Myf6myogenic factor 6
U008102Myod1myogenic differentiation 1
U032202Myf5myogenic factor 5

GO terms:
GO:0007275 development
GO:0007519 myogenesis
GO:0030154 cell differentiation
GO:0003705 RNA polymerase II transcription factor activity, enhancer binding
GO:0007517 muscle development
GO:0045445 myoblast differentiation
GO:0007518 myoblast cell fate determination
GO:0042803 protein homodimerization activity
GO:0030141 secretory granule
GO:0046982 protein heterodimerization activity
GO:0016563 transcriptional activator activity

Protein domains:
IPR001092 Basic helix-loop-helix dimerisation region bHLH
IPR002546 Myogenic basic muscle-specific protein
IPR011598 Helix-loop-helix DNA-binding
IPR001093 IMP dehydrogenase/GMP reductase
IPR009057 Homeodomain-like
IPR001606 AT-rich interaction region
IPR000519 P-type trefoil

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend