CisView: Mouse (mm6, March2005)
Transcription factor binding site MIT_064AP1

Source: Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Kellis M. 2005. Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature 434(7031):338-345.
TF group: AP1       TFBS class: bZIP = Leucine zipper       Code: 1.1.1
Pattern = TTANTCA     Class: AP1     Allowed mismatch: 0.2     Palindrome
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Genes (trans-elements):
U-clusterSymbol
Annotation
U001694Lhx2LIM homeobox protein 2
U028220FosbFBJ osteosarcoma oncogene B
U038721Fosl1fos-like antigen 1
U117162JunbJun-B oncogene
U025271JunJun oncogene
U014210FosFBJ osteosarcoma oncogene

GO terms:
GO:0000074 regulation of cell cycle
GO:0007399 neurogenesis
GO:0035026 leading edge cell differentiation
GO:0009953 dorsal/ventral pattern formation
GO:0006508 proteolysis and peptidolysis
GO:0007498 mesoderm development
GO:0008270 zinc ion binding
GO:0007420 brain development
GO:0004289 subtilase activity

Protein domains:
IPR004827 Basic-leucine zipper (bZIP) transcription factor
IPR008917 Eukaryotic transcription factor, DNA-binding
IPR011616 bZIP transcription factor, bZIP_1
IPR000837 Fos transforming protein
IPR005643 Jun-like transcription factor
IPR002112 Transcription factor Jun
IPR001093 IMP dehydrogenase/GMP reductase
IPR007107 LIM homeobox
IPR009057 Homeodomain-like
IPR000209 Peptidase S8 and S53, subtilisin, kexin, sedolisin
IPR011700 Basic leucine zipper
IPR001781 Zn-binding protein, LIM
IPR001356 Homeobox

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend