CisView: Mouse (mm6, March2005)
Transcription factor binding site MIT_083HNF3

Source: Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Kellis M. 2005. Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature 434(7031):338-345.
TF group: HNF3       TFBS class: FH = Fork head       Code: 3.3.2.0
Pattern = TGTTTGY     Class: HNF3     Allowed mismatch: 0.2
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Genes (trans-elements):
U-clusterSymbol
Annotation
U002787Hnf4ahepatic nuclear factor 4, alpha
U033976Foxa1forkhead box A1
U023461Foxa2forkhead box A2
U028212Foxa3forkhead box A3
U002787Hnf4ahepatic nuclear factor 4, alpha

GO terms:
GO:0004872 receptor activity
GO:0004879 ligand-dependent nuclear receptor activity
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0009267 cellular response to starvation
GO:0001678 cell glucose homeostasis

Protein domains:
IPR001766 Fork head transcription factor
IPR008946 Steroid nuclear receptor, ligand-binding
IPR000324 Vitamin D receptor
IPR000003 Retinoid X receptor
IPR001723 Steroid hormone receptor
IPR000536 Ligand-binding region of nuclear hormone receptor
IPR001628 Zn-finger, C4-type steroid receptor

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend