CisView: Mouse (mm6, March2005)
Transcription factor binding site MIT_111AML

Source: Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Kellis M. 2005. Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature 434(7031):338-345.
TF group: AML       TFBS class: runt       Code: 4.11.1
Pattern = RACCACAR     Class: AML     Allowed mismatch: 0.2
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Genes (trans-elements):
U-clusterSymbol
Annotation
U058005Runx1runt related transcription factor 1
U037830Runx2runt related transcription factor 2
U009738Cbfbcore binding factor beta

GO terms:
GO:0001649 osteoblast differentiation
GO:0030099 myeloid cell differentiation
GO:0001501 skeletal development
GO:0030098 lymphocyte differentiation
GO:0001503 ossification
GO:0003713 transcription coactivator activity
GO:0042487 regulation of odontogenesis (sensu Vertebrata)
GO:0005524 ATP binding
GO:0003682 chromatin binding
GO:0042475 odontogenesis (sensu Vertebrata)
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway

Protein domains:
IPR008967 p53-like transcription factor, DNA-binding
IPR000040 Acute myeloid leukemia 1 protein (AML 1)/Runt
IPR003417 Core binding factor, beta subunit

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend