CisView: Mouse (mm6, March2005)

Transcription factor binding site TF_AHR

Database: TRANSFAC
Source: Matys V, Fricke E, Geffers R, Gößling E, Haubrock M, et al. 2003. TRANSFAC: transcriptional regulation, from patterns to profiles. Nucleic Acids Res., 31, 374-378.
TF group: AHR       TFBS class: bHLH = Helix-loop-helix       Code: 1.2.6.0
Pattern = TYGCGTGM (core elements are bold)     Class: AHR     Allowed mismatch: 0.094     Palindrome
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Matrixes from TRANSFAC:
Matrix
Pattern
Orientation
V$AHR_01 CCYCNRRSTNGCGTGASA
+
V$AHRARNT_01 __KNNKNNTYGCGTGC
+
V$AHRARNT_02 ___GRGKATYGCGTGMCWN
+

Genes (trans-elements):
U-clusterSymbol
Annotation
U003569Arntaryl hydrocarbon receptor nuclear translocator
U013861Ahraryl-hydrocarbon receptor
U028811Arnt2aryl hydrocarbon receptor nuclear translocator 2
U034072Hif1ahypoxia inducible factor 1, alpha subunit
U034967Ahrraryl-hydrocarbon receptor repressor

GO terms:
GO:0004872 receptor activity
GO:0007165 signal transduction
GO:0006805 xenobiotic metabolism
GO:0009636 response to toxin
GO:0045941 positive regulation of transcription
GO:0007049 cell cycle
GO:0003713 transcription coactivator activity
GO:0046982 protein heterodimerization activity
GO:0016563 transcriptional activator activity

Protein domains:
IPR001092 Basic helix-loop-helix dimerisation region bHLH
IPR001067 Nuclear translocator
IPR000014 PAS
IPR011598 Helix-loop-helix DNA-binding
IPR001610 PAC motif
IPR001093 IMP dehydrogenase/GMP reductase

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend