CisView: Mouse (mm6, March2005)
Transcription factor binding site TF_AML

Database: TRANSFAC
Source: Matys V, Fricke E, Geffers R, Gößling E, Haubrock M, et al. 2003. TRANSFAC: transcriptional regulation, from patterns to profiles. Nucleic Acids Res., 31, 374-378.
TF group: AML       TFBS class: runt       Code: 4.11.1
Pattern = TGTGGT (core elements are bold)     Class: AML     Allowed mismatch: 0
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Matrixes from TRANSFAC:
Matrix
Pattern
Orientation
V$AML1_01 TGTGGT
+

Genes (trans-elements):
U-clusterSymbol
Annotation
U009738Cbfbcore binding factor beta
U037830Runx2runt related transcription factor 2
U037315Runx1runt related transcription factor 1

GO terms:
GO:0001649 osteoblast differentiation
GO:0001501 skeletal development
GO:0005524 ATP binding
GO:0030099 myeloid cell differentiation
GO:0030098 lymphocyte differentiation
GO:0001503 ossification
GO:0003713 transcription coactivator activity
GO:0042487 regulation of odontogenesis (sensu Vertebrata)
GO:0030182 neuron differentiation
GO:0003682 chromatin binding
GO:0042475 odontogenesis (sensu Vertebrata)
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway

Protein domains:
IPR008967 p53-like transcription factor, DNA-binding
IPR000040 Acute myeloid leukemia 1 protein (AML 1)/Runt
IPR001093 IMP dehydrogenase/GMP reductase
IPR003417 Core binding factor, beta subunit

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend