CisView: Mouse (mm6, March2005)
Transcription factor binding site TF_AP1

Database: TRANSFAC
Source: Matys V, Fricke E, Geffers R, Gößling E, Haubrock M, et al. 2003. TRANSFAC: transcriptional regulation, from patterns to profiles. Nucleic Acids Res., 31, 374-378.
TF group: AP1       TFBS class: bZIP = Leucine zipper       Code: 1.1.1
Pattern = VTGACTMAB (core elements are bold)     Class: AP1     Allowed mismatch: 0.026     Palindrome
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Matrixes from TRANSFAC:
Matrix
Pattern
Orientation
V$AP1FJ_Q2 RSTGACTNMNW
+
V$AP1_Q2 RSTGACTNANW
+
V$AP1_Q6 NNTGACTCANN
+
V$AP1_Q4 RGTGACTMANN
+

Genes (trans-elements):
U-clusterSymbol
Annotation
U001694Lhx2LIM homeobox protein 2
U014210FosFBJ osteosarcoma oncogene
U025271JunJun oncogene
U028220FosbFBJ osteosarcoma oncogene B
U038721Fosl1fos-like antigen 1
U117162JunbJun-B oncogene

GO terms:
GO:0000074 regulation of cell cycle
GO:0007399 neurogenesis
GO:0035026 leading edge cell differentiation
GO:0009953 dorsal/ventral pattern formation
GO:0006508 proteolysis and peptidolysis
GO:0007498 mesoderm development
GO:0008270 zinc ion binding
GO:0007420 brain development
GO:0004289 subtilase activity

Protein domains:
IPR004827 Basic-leucine zipper (bZIP) transcription factor
IPR008917 Eukaryotic transcription factor, DNA-binding
IPR011616 bZIP transcription factor, bZIP_1
IPR000837 Fos transforming protein
IPR005643 Jun-like transcription factor
IPR002112 Transcription factor Jun
IPR001093 IMP dehydrogenase/GMP reductase
IPR007107 LIM homeobox
IPR009057 Homeodomain-like
IPR000209 Peptidase S8 and S53, subtilisin, kexin, sedolisin
IPR011700 Basic leucine zipper
IPR001781 Zn-binding protein, LIM
IPR001356 Homeobox

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend