CisView: Mouse (mm6, March2005)
Transcription factor binding site TF_AP2A

Database: TRANSFAC
Source: Matys V, Fricke E, Geffers R, Gößling E, Haubrock M, et al. 2003. TRANSFAC: transcriptional regulation, from patterns to profiles. Nucleic Acids Res., 31, 374-378.
TF group: AP2A       TFBS class: bHSH = Helix-span-helix       Code: 1.6.1.0.1
Pattern = GCCBBVRGS (core elements are bold)     Class: AP2A     Allowed mismatch: 0.005     Palindrome
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Matrixes from TRANSFAC:
Matrix
Pattern
Orientation
V$AP2ALPHA_01 GCCNNNRGS
+

Genes (trans-elements):
U-clusterSymbol
Annotation
U028505Ap2a1adaptor protein complex AP-2, alpha 1 subunit

GO terms:
GO:0005905 coated pit
GO:0030117 membrane coat
GO:0006897 endocytosis
GO:0006461 protein complex assembly
GO:0030130 clathrin coat of trans-Golgi network vesicle
GO:0005794 Golgi apparatus
GO:0005198 structural molecule activity
GO:0015031 protein transport
GO:0006886 intracellular protein transport
GO:0030141 secretory granule
GO:0016192 vesicle-mediated transport

Protein domains:
IPR002553 Adaptin, N-terminal
IPR003006 Immunoglobulin/major histocompatibility complex
IPR009028 AP2 clathrin adaptor, alpha and beta chain, appendage
IPR003164 AP2 clathrin adaptin, alpha chain, C-terminal
IPR001093 IMP dehydrogenase/GMP reductase
IPR008152 Alpha/gamma adaptin, C-terminal

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend