CisView: Mouse (mm6, March2005)

Transcription factor binding site TF_CEBP

Database: TRANSFAC
Source: Matys V, Fricke E, Geffers R, Gößling E, Haubrock M, et al. 2003. TRANSFAC: transcriptional regulation, from patterns to profiles. Nucleic Acids Res., 31, 374-378.
TF group: CEBP       TFBS class: bZIP = Leucine zipper       Code: 1.1.3.0
Pattern = NNATTRVCCAATSA (core elements are bold)     Class: CEBP     Allowed mismatch: 0.109     Palindrome
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Matrixes from TRANSFAC:
Matrix
Pattern
Orientation
V$CAAT_C ________ACCAATCANCNNGCYYS
+
V$CAAT_01 ____NNNRRCCAATSA
+
V$CEBPB_01 __RNRTKDNGMAAKNN
+
V$CEBPA_01 __NNATTRCNNAANNN
+
V$CEBPB_02 __NKNTTGCNYAAYNN
+
V$CEBP_Q2 __NNATTGCNNAANNN
+
V$CEBP_C _NGWVTKNKGYAAKNSAY
+
V$CHOP_01 GGGKATTGCAYNN
-

Genes (trans-elements):
U-clusterSymbol
Annotation
U002854CebpbCCAAT/enhancer binding protein (C/EBP), beta
U007965CebpaCCAAT/enhancer binding protein (C/EBP), alpha
U016849CebpdCCAAT/enhancer binding protein (C/EBP), delta
U028433CebpgCCAAT/enhancer binding protein (C/EBP), gamma
U038072CebpzCCAAT/enhancer binding protein zeta
U248406CebpeCCAAT/enhancer binding protein (C/EBP), epsilon

GO terms:
GO:0042803 protein homodimerization activity
GO:0030225 macrophage differentiation
GO:0001892 embryonic placenta development
GO:0045444 fat cell differentiation
GO:0042089 cytokine biosynthesis
GO:0006909 phagocytosis
GO:0006916 anti-apoptosis
GO:0045408 regulation of interleukin-6 biosynthesis
GO:0006917 induction of apoptosis
GO:0007005 mitochondrion organization and biogenesis
GO:0008285 negative regulation of cell proliferation
GO:0042742 defense response to bacteria
GO:0030182 neuron differentiation

Protein domains:
IPR011700 Basic leucine zipper
IPR004827 Basic-leucine zipper (bZIP) transcription factor
IPR008917 Eukaryotic transcription factor, DNA-binding
IPR005612 CBF/Mak21

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend