CisView: Mouse (mm6, March2005)
Transcription factor binding site TF_CREB

Database: TRANSFAC
Source: Matys V, Fricke E, Geffers R, Gößling E, Haubrock M, et al. 2003. TRANSFAC: transcriptional regulation, from patterns to profiles. Nucleic Acids Res., 31, 374-378.
TF group: CREB       TFBS class: bZIP = Leucine zipper       Code: 1.1
Pattern = TGACGTMA (core elements are bold)     Class: CREB     Allowed mismatch: 0.185     Palindrome
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Matrixes from TRANSFAC:
Matrix
Pattern
Orientation
V$CREB_01 ____TGACGTMA
+
V$CREBP1_01 ____TTACGTAA
+
V$CREBP1CJUN_01 ____TGACGTYA
+
V$CREB_02 NNGNTGACGTNN
+
V$CREB_Q2 __NSTGACGTAA
+
V$CREB_Q4 __NSTGACGTMA
+
V$CREBP1_Q2 __VGTGACGTMA
+

Genes (trans-elements):
U-clusterSymbol
Annotation
U012517Ifi47,Olfr56interferon gamma inducible protein 47
U016447Atf4activating transcription factor 4
U016666Atf1activating transcription factor 1
U022038Atf6activating transcription factor 6
U022200Atf3activating transcription factor 3
U022749Atf2activating transcription factor 2
U028500Atf5activating transcription factor 5
U036699Npff,Atf7neuropeptide FF-amide peptide precursor
U038164CremcAMP responsive element modulator
U230618Creb1cAMP responsive element binding protein 1
U319718Ovgp1oviductal glycoprotein 1

GO terms:
GO:0005783 endoplasmic reticulum
GO:0008270 zinc ion binding
GO:0006094 gluconeogenesis
GO:0007165 signal transduction
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0004872 receptor activity
GO:0015986 ATP synthesis coupled proton transport
GO:0004930 G-protein coupled receptor activity
GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism
GO:0006952 defense response
GO:0006818 hydrogen transport
GO:0005641 nuclear membrane lumen
GO:0007608 perception of smell
GO:0005654 nucleoplasm
GO:0006916 anti-apoptosis
GO:0007186 G-protein coupled receptor protein signaling pathway
GO:0042127 regulation of cell proliferation
GO:0046933 hydrogen-transporting ATP synthase activity, rotational mechanism
GO:0016469 proton-transporting two-sector ATPase complex
GO:0000074 regulation of cell cycle
GO:0006986 response to unfolded protein
GO:0046961 hydrogen-transporting ATPase activity, rotational mechanism
GO:0004984 olfactory receptor activity
GO:0005635 nuclear membrane
GO:0006457 protein folding
GO:0003713 transcription coactivator activity
GO:0005524 ATP binding
GO:0001584 rhodopsin-like receptor activity
GO:0006950 response to stress
GO:0016563 transcriptional activator activity
GO:0006990 unfolded protein response, positive regulation of target gene transcription
GO:0005887 integral to plasma membrane
GO:0007283 spermatogenesis
GO:0005789 endoplasmic reticulum membrane
GO:0016564 transcriptional repressor activity
GO:0004869 cysteine protease inhibitor activity

Protein domains:
IPR011616 bZIP transcription factor, bZIP_1
IPR004827 Basic-leucine zipper (bZIP) transcription factor
IPR008917 Eukaryotic transcription factor, DNA-binding
IPR001093 IMP dehydrogenase/GMP reductase
IPR000837 Fos transforming protein
IPR007087 Zn-finger, C2H2 type
IPR001630 cAMP response element binding (CREB) protein
IPR003102 Coactivator CBP, pKID
IPR008954 Moesin
IPR000194 H+-transporting two-sector ATPase, alpha/beta subunit, central region
IPR003006 Immunoglobulin/major histocompatibility complex
IPR000725 Olfactory receptor
IPR011700 Basic leucine zipper
IPR000215 Proteinase inhibitor I4, serpin
IPR000276 Rhodopsin-like GPCR superfamily
IPR007743 Interferon-inducible GTPase
IPR000010 Proteinase inhibitor I25, cystatin

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend