CisView: Mouse (mm6, March2005)
Transcription factor binding site TF_HAND

Database: TRANSFAC
Source: Matys V, Fricke E, Geffers R, Gößling E, Haubrock M, et al. 2003. TRANSFAC: transcriptional regulation, from patterns to profiles. Nucleic Acids Res., 31, 374-378.
TF group: HAND       TFBS class: bHLH = Helix-loop-helix       Code: 1.2
Pattern = TCTGGMWTT (core elements are bold)     Class: HAND     Allowed mismatch: 0.02
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Matrixes from TRANSFAC:
Matrix
Pattern
Orientation
V$HAND1E47_01 NNNNGNRTCTGGMWTT
+

Genes (trans-elements):
U-clusterSymbol
Annotation
U032010Tcfe2atranscription factor E2a
U032799Hand1heart and neural crest derivatives expressed transcript 1

GO terms:
GO:0042803 protein homodimerization activity
GO:0046982 protein heterodimerization activity
GO:0001525 angiogenesis
GO:0007275 development
GO:0007507 heart development

Protein domains:
IPR001092 Basic helix-loop-helix dimerisation region bHLH
IPR009057 Homeodomain-like
IPR001093 IMP dehydrogenase/GMP reductase
IPR011598 Helix-loop-helix DNA-binding

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend