CisView: Mouse (mm6, March2005)
Transcription factor binding site TF_IRF

Database: TRANSFAC
Source: Matys V, Fricke E, Geffers R, Gößling E, Haubrock M, et al. 2003. TRANSFAC: transcriptional regulation, from patterns to profiles. Nucleic Acids Res., 31, 374-378.
TF group: IRF       TFBS class: MYB/ETS = Tryptophan clusters       Code: 3.5.3.0
Pattern = RAAAGYGAAA (core elements are bold)     Class: IRF     Allowed mismatch: 0.137
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Matrixes from TRANSFAC:
Matrix
Pattern
Orientation
V$IRF1_01 __SAAAAGYGAAA
+
V$IRF2_01 __GAAAAGYGAAA
+
V$ISRE_01 _GGRAAAGSGAAACT
-
V$IRF7_01 TNSGAAWNCGAAANTNNN
+

Genes (trans-elements):
U-clusterSymbol
Annotation
U006617Irf5interferon regulatory factor 5
U008060Irf3interferon regulatory factor 3
U009319Irf2interferon regulatory factor 2
U009890Icsbp1interferon consensus sequence binding protein 1
U012603Irf1interferon regulatory factor 1
U029451Irf7interferon regulatory factor 7
U321621Irf4interferon regulatory factor 4

GO terms:
GO:0006955 immune response
GO:0042803 protein homodimerization activity
GO:0030099 myeloid cell differentiation
GO:0045084 positive regulation of interleukin-12 biosynthesis

Protein domains:
IPR001346 Interferon regulatory factor
IPR008984 SMAD/FHA

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend