CisView: Mouse (mm6, March2005)
Transcription factor binding site TF_MYOD

Database: TRANSFAC
Source: Matys V, Fricke E, Geffers R, Gößling E, Haubrock M, et al. 2003. TRANSFAC: transcriptional regulation, from patterns to profiles. Nucleic Acids Res., 31, 374-378.
TF group: MYOD       TFBS class: bHLH = Helix-loop-helix       Code: 1.2
Pattern = VCAGGTGB (core elements are bold)     Class: MYOD     Allowed mismatch: 0.002     Palindrome
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Matrixes from TRANSFAC:
Matrix
Pattern
Orientation
V$MYOD_01 SRACAGGTGKYG
+
V$MYOD_Q6 _RNCAGGTGN
-
V$LMO2COM_01 CNNCAGGTGBNN
+
V$AREB6_01 ABSCAGGTRNRNN
-
V$AREB6_02 NNSCAGGTGSNS
-
V$AREB6_03 GNMCAGGTGYNB
-

Genes (trans-elements):
U-clusterSymbol
Annotation
U008102Myod1myogenic differentiation 1
U031072Tcf12transcription factor 12
U031895Arid5bAT rich interactive domain 5B (Mrf1 like)
U032010Tcfe2atranscription factor E2a
U032202Myf5myogenic factor 5
U032203Myf6myogenic factor 6
U037643Tff3trefoil factor 3, intestinal
U042448Mef2dmyocyte enhancer factor 2D
U173038Tcf4transcription factor 4

GO terms:
GO:0007275 development
GO:0007519 myogenesis
GO:0030154 cell differentiation
GO:0003705 RNA polymerase II transcription factor activity, enhancer binding
GO:0007517 muscle development
GO:0045445 myoblast differentiation
GO:0007518 myoblast cell fate determination
GO:0042803 protein homodimerization activity
GO:0030141 secretory granule
GO:0046982 protein heterodimerization activity
GO:0016563 transcriptional activator activity

Protein domains:
IPR001092 Basic helix-loop-helix dimerisation region bHLH
IPR001093 IMP dehydrogenase/GMP reductase
IPR002546 Myogenic basic muscle-specific protein
IPR011598 Helix-loop-helix DNA-binding
IPR009057 Homeodomain-like
IPR001606 AT-rich interaction region
IPR000519 P-type trefoil

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend