CisView: Mouse (mm6, March2005)

Transcription factor binding site TF_NF1

Database: TRANSFAC
Source: Matys V, Fricke E, Geffers R, Gößling E, Haubrock M, et al. 2003. TRANSFAC: transcriptional regulation, from patterns to profiles. Nucleic Acids Res., 31, 374-378.
TF group: NF1       TFBS class: NF1       Code: 4.12.2.0
Pattern = TTGGCWNGNRBCCHD (core elements are bold)     Class: NF1     Allowed mismatch: 0.028     Palindrome
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Matrixes from TRANSFAC:
Matrix
Pattern
Orientation
V$NF1_Q6 NNTTGGCNNNNNNCCNNN
+

Genes (trans-elements):
U-clusterSymbol
Annotation
U008812Ctf1cardiotrophin 1
U013036Nf1neurofibromatosis 1
U147160Ctf2cardiotrophin 2

GO terms:
GO:0005125 cytokine activity
GO:0007275 development
GO:0005096 GTPase activator activity
GO:0040007 growth
GO:0045685 regulation of glial cell differentiation

Protein domains:
IPR010681 Plethodontid receptivity factor PRF
IPR009079 Four-helical cytokine
IPR001936 Ras GTPase-activating protein
IPR001093 IMP dehydrogenase/GMP reductase
IPR000151 Ciliary neurotrophic factor, CNTF
IPR001251 Cellular retinaldehyde-binding/triple function, C-terminal
IPR008936 Rho GTPase activation protein

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend