CisView: Mouse (mm6, March2005)
Transcription factor binding site TF_NFAT

Database: TRANSFAC
Source: Matys V, Fricke E, Geffers R, Gößling E, Haubrock M, et al. 2003. TRANSFAC: transcriptional regulation, from patterns to profiles. Nucleic Acids Res., 31, 374-378.
TF group: NFAT       TFBS class: RHR = Rel homology region       Code: 4.1.3.0
Pattern = WGGAAAAH (core elements are bold)     Class: NFAT     Allowed mismatch: 0.002
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Matrixes from TRANSFAC:
Matrix
Pattern
Orientation
V$NFAT_Q6 NANWGGAAAANN
+

Genes (trans-elements):
U-clusterSymbol
Annotation
U009766Nfatc3nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
U023695Nfatc2nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
U038611Nfatc1nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
U042927Nfat5nuclear factor of activated T-cells 5

GO terms:
GO:0007507 heart development
GO:0045333 cellular respiration
GO:0006508 proteolysis and peptidolysis
GO:0004197 cysteine-type endopeptidase activity
GO:0000082 G1/S transition of mitotic cell cycle
GO:0006351 transcription, DNA-dependent
GO:0001837 epithelial to mesenchymal transition
GO:0006816 calcium ion transport

Protein domains:
IPR008967 p53-like transcription factor, DNA-binding
IPR008366 Nuclear factor of activated T cells (NFAT)
IPR002909 Cell surface receptor IPT/TIG
IPR001093 IMP dehydrogenase/GMP reductase
IPR011539 Rel homology
IPR000169 Peptidase, cysteine peptidase active site

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend