CisView: Mouse (mm6, March2005)

Transcription factor binding site TF_PAX6

Database: TRANSFAC
Source: Matys V, Fricke E, Geffers R, Gößling E, Haubrock M, et al. 2003. TRANSFAC: transcriptional regulation, from patterns to profiles. Nucleic Acids Res., 31, 374-378.
TF group: PAX6       TFBS class: PAX = Paired box       Code: 3.2
Pattern = TTCACGCWTGAVT (core elements are bold)     Class: PAX6     Allowed mismatch: 0.2     Palindrome
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Matrixes from TRANSFAC:
Matrix
Pattern
Orientation
V$PAX6_01 NNNNTTCACGCWTGANTKNNN
+

Genes (trans-elements):
U-clusterSymbol
Annotation
U002205Pax6paired box gene 6

GO terms:
GO:0050767 regulation of neurogenesis
GO:0009953 dorsal/ventral pattern formation
GO:0007409 axonogenesis
GO:0007435 salivary gland morphogenesis
GO:0001709 cell fate determination
GO:0009952 anterior/posterior pattern formation
GO:0030154 cell differentiation
GO:0001747 eye morphogenesis (sensu Mammalia)
GO:0045165 cell fate commitment
GO:0007275 development
GO:0042462 eye photoreceptor cell development
GO:0030334 regulation of cell migration
GO:0001656 metanephros development
GO:0007411 axon guidance
GO:0008285 negative regulation of cell proliferation
GO:0030900 forebrain development
GO:0007420 brain development

Protein domains:
IPR009057 Homeodomain-like
IPR001093 IMP dehydrogenase/GMP reductase
IPR001356 Homeobox
IPR007104 Paired-like homeobox
IPR001523 Paired box protein, N-terminal

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend