CisView: Mouse (mm6, March2005)
Transcription factor binding site TF_PPAR

Database: TRANSFAC
Source: Matys V, Fricke E, Geffers R, Gößling E, Haubrock M, et al. 2003. TRANSFAC: transcriptional regulation, from patterns to profiles. Nucleic Acids Res., 31, 374-378.
TF group: PPAR       TFBS class: HR = Hormone receptor       Code: 2.1.2
Pattern = RGGTCAAAGGTCA (core elements are bold)     Class: PPAR     Allowed mismatch: 0.2
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Matrixes from TRANSFAC:
Matrix
Pattern
Orientation
V$PPARA_01 CARAACTAGGNCAAAGGTCA
+
V$PPARG_01 ___NNWGRGGTCAAAGGTCAN
+
V$PPARG_03 ___WASNRGGNCAAAGGTCA
+

Genes (trans-elements):
U-clusterSymbol
Annotation
U007293Ppargperoxisome proliferator activated receptor gamma
U016529Pparaperoxisome proliferator activated receptor alpha
U017743Ppardperoxisome proliferator activator receptor delta

GO terms:
GO:0004872 receptor activity
GO:0004879 ligand-dependent nuclear receptor activity
GO:0003707 steroid hormone receptor activity
GO:0006629 lipid metabolism
GO:0008544 epidermis development
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0016563 transcriptional activator activity
GO:0016564 transcriptional repressor activity
GO:0008283 cell proliferation
GO:0008366 nerve ensheathment
GO:0006006 glucose metabolism
GO:0045165 cell fate commitment
GO:0045444 fat cell differentiation
GO:0042640 anagen
GO:0030855 epithelial cell differentiation
GO:0006954 inflammatory response
GO:0006631 fatty acid metabolism
GO:0019217 regulation of fatty acid metabolism

Protein domains:
IPR008946 Steroid nuclear receptor, ligand-binding
IPR003074 Peroxisome proliferator-activated receptor
IPR001723 Steroid hormone receptor
IPR000536 Ligand-binding region of nuclear hormone receptor
IPR001628 Zn-finger, C4-type steroid receptor
IPR001093 IMP dehydrogenase/GMP reductase
IPR003076 Peroxisome proliferator-activated receptor, alpha
IPR000324 Vitamin D receptor
IPR003077 Peroxisome proliferator-activated receptor, gamma
IPR003075 Peroxisome proliferator-activated receptor, beta

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend