CisView: Mouse (mm6, March2005)
Transcription factor binding site TF_ZIC

Database: TRANSFAC
Source: Matys V, Fricke E, Geffers R, Gößling E, Haubrock M, et al. 2003. TRANSFAC: transcriptional regulation, from patterns to profiles. Nucleic Acids Res., 31, 374-378.
TF group: ZIC       TFBS class: ZF = Zinc finger       Code: 2.3.2.3
Pattern = KGGGTGGTC (core elements are bold)     Class: ZIC     Allowed mismatch: 0.185
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Matrixes from TRANSFAC:
Matrix
Pattern
Orientation
V$ZIC1_01 KGGGTGGTC
+
V$ZIC2_01 KGGGTGGTC
+
V$ZIC3_01 NGGGKGGTC
+

Genes (trans-elements):
U-clusterSymbol
Annotation
U031186Zic1zinc finger protein of the cerebellum 1
U015999Zic2Zic finger protein of the cerebellum 2
U043760Zic3zinc finger protein of the cerebellum 3
U010850Zic4zinc finger protein of the cerebellum 4
U035955Zic5zinc finger protein of the cerebellum 5
U021691Gli2GLI-Kruppel family member GLI2
U032336Gli1GLI-Kruppel family member GLI1
U235558Gli3GLI-Kruppel family member GLI3

GO terms:
GO:0008270 zinc ion binding
GO:0030154 cell differentiation
GO:0007399 neurogenesis
GO:0001843 neural tube closure
GO:0007275 development
GO:0007165 signal transduction
GO:0045941 positive regulation of transcription
GO:0007417 central nervous system development
GO:0001501 skeletal development
GO:0008284 positive regulation of cell proliferation
GO:0007389 pattern specification
GO:0008017 microtubule binding
GO:0003713 transcription coactivator activity
GO:0030900 forebrain development
GO:0007610 behavior
GO:0007283 spermatogenesis
GO:0030902 hindbrain development
GO:0048066 pigmentation

Protein domains:
IPR007087 Zn-finger, C2H2 type
IPR001093 IMP dehydrogenase/GMP reductase

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend