CisView Mouse (mm6, March 2005)

Main Gene Ontology terms for targets of TF_AP4

No.GO annotation
Total
genes
with GO
Location
Max no. of
genes with
TF_AP4
TF_AP4 alone
In pair
with
1GO:0003700 transcription factor activity
719
before_TSS
60
yes
 
2GO:0048513 organ development
852
at_TSS,before_TSS
57
yes
MIT_055NFAT, TF_AP2A,
3GO:0005975 carbohydrate metabolism
308
at_TSS
55
yes
 
4GO:0007166 cell surface receptor linked signal transduction
859
before_TSS
51
yes
 
5GO:0044262 cellular carbohydrate metabolism
205
at_TSS
38
yes
many
6GO:0005509 calcium ion binding
487
at_TSS
37
yes
 
7GO:0007186 G-protein coupled receptor protein signaling pathway
495
before_TSS,after_TSS
33
yes
 
8GO:0004713 protein-tyrosine kinase activity
381
at_TSS
29
yes
 
9GO:0030001 metal ion transport
288
before_TSS
29
yes
 
10GO:0004930 G-protein coupled receptor activity
357
before_TSS,after_TSS
26
yes
 
11GO:0051276 chromosome organization and biogenesis
220
before_TSS,after_TSS
24
yes
many
12GO:0001584 rhodopsin-like receptor activity
283
before_TSS
24
yes
 
13GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
208
before_TSS,after_TSS
24
yes
many
14GO:0006259 DNA metabolism
427
before_TSS
24
 
TF_STAF,
15GO:0007399 nervous system development
301
at_TSS
23
yes
 
16GO:0006325 establishment and/or maintenance of chromatin architecture
179
before_TSS,after_TSS
21
yes
many
17GO:0006323 DNA packaging
188
before_TSS,after_TSS
21
yes
many
18GO:0006461 protein complex assembly
123
before_TSS,after_TSS
20
yes
many
19GO:0006357 regulation of transcription from RNA polymerase II promoter
191
before_TSS
20
yes
 
20GO:0006333 chromatin assembly or disassembly
121
before_TSS,after_TSS
19
yes
many
21GO:0006807 nitrogen compound metabolism
268
before_TSS
19
 
TF_SREBP,
22GO:0031497 chromatin assembly
95
before_TSS,after_TSS
19
yes
many
23GO:0006334 nucleosome assembly
86
before_TSS,after_TSS
19
yes
many
24GO:0007389 pattern specification
128
after_TSS
18
yes
 
25GO:0050876 reproductive physiological process
33
before_TSS
18
yes
 
26GO:0048609 reproductive organismal physiological process
33
before_TSS
18
yes
 
27GO:0051243 negative regulation of cellular physiological process
330
before_TSS
17
 
TF_MAF,
28GO:0007167 enzyme linked receptor protein signaling pathway
157
before_TSS
17
yes
 
29GO:0009790 embryonic development
170
before_TSS
17
yes
 
30GO:0016051 carbohydrate biosynthesis
57
at_TSS
16
yes
 
31GO:0007517 muscle development
99
at_TSS,before_TSS
14
yes
 
32GO:0016526 G-protein coupled receptor activity, unknown ligand
33
after_TSS
14
yes
 
33GO:0008289 lipid binding
131
at_TSS
14
yes
TF_SP1,
34GO:0008237 metallopeptidase activity
177
before_TSS
12
 
TF_TAL1,
35GO:0045893 positive regulation of transcription, DNA-dependent
86
before_TSS
11
yes
 
36GO:0045944 positive regulation of transcription from RNA polymerase II promoter
73
before_TSS
11
yes
 
37GO:0009792 embryonic development (sensu Metazoa)
85
before_TSS
11
yes
 
38GO:0045595 regulation of cell differentiation
75
before_TSS
10
 
TF_AP2,

Pairs of TF_AP4 binding sites with other TFBS

No.TFBS
Location
Total GO-s
Main GO annotation
N pairs for
main GO
Total genes
for main GO
1TF_STAF
before_TSS
9
GO:0006259 DNA metabolism
24
427
2TF_SP1
at_TSS,before_TSS
9
GO:0051276 chromosome organization and biogenesis
22
220
3TF_PAX4
before_TSS
8
GO:0051276 chromosome organization and biogenesis
18
220
4TF_E2F
after_TSS
8
GO:0051276 chromosome organization and biogenesis
13
220
5TF_AHR
before_TSS,after_TSS
8
GO:0051276 chromosome organization and biogenesis
24
220
6TF_ATF1
at_TSS,before_TSS
4
GO:0006461 protein complex assembly
13
123
7TF_CREB
at_TSS,before_TSS
4
GO:0044262 cellular carbohydrate metabolism
12
205
8TF_SREBP
before_TSS
1
GO:0006807 nitrogen compound metabolism
19
268
9TF_MAF
before_TSS
1
GO:0051243 negative regulation of cellular physiological process
17
330
10TF_ATF6
at_TSS
1
GO:0044262 cellular carbohydrate metabolism
11
205
11TF_TAL1
before_TSS
1
GO:0008237 metallopeptidase activity
12
177
12MIT_055NFAT
before_TSS
1
GO:0048513 organ development
54
852
13TF_ARNT
at_TSS
1
GO:0044262 cellular carbohydrate metabolism
11
205
14TF_AP2A
before_TSS
1
GO:0048513 organ development
47
852
15TF_AP2
before_TSS
1
GO:0045595 regulation of cell differentiation
10
75

Details on Gene Ontology terms for targets of TF_AP4

Total number of genes = 12103
No.In pair
with
Multi-
ple
Conser-
ved
Location
Frequency
in list
U-clusters
in list
Genes with TFBS
in list, %
Genes with TFBS
total, %
Ratio
z
p
FDR
GO annotation
1none
 
yes
before_TSS
60
719
8.3
5.4
1.53
3.52
0.0004
0.0017
GO:0003700 transcription factor activity
2none
 
yes
at_TSS
57
852
6.6
4.2
1.57
3.667
0.0002
0.0016
GO:0048513 organ development
3none
 
 
at_TSS
55
308
17.8
10.4
1.7
4.29
0
0.0032
GO:0005975 carbohydrate metabolism
4none
yes
 
before_TSS
51
859
5.9
3.7
1.59
3.566
0.0003
0.0663
GO:0007166 cell surface receptor linked signal transduction
5none
 
 
at_TSS
38
205
18.5
10.4
1.77
3.805
0.0001
0.0519
GO:0044262 cellular carbohydrate metabolism
6none
 
yes
at_TSS
37
487
7.5
4.2
1.78
3.742
0.0001
0.0111
GO:0005509 calcium ion binding
7none
yes
 
before_TSS
33
495
6.6
3.7
1.79
3.54
0.0004
0.0366
GO:0007186 G-protein coupled receptor protein signaling pathway
8none
 
yes
at_TSS
29
381
7.6
4.2
1.79
3.309
0.0009
0.038
GO:0004713 protein-tyrosine kinase activity
9none
 
yes
before_TSS
29
288
10
5.4
1.84
3.491
0.0004
0.044
GO:0030001 metal ion transport
10none
yes
 
before_TSS
26
357
7.2
3.7
1.95
3.613
0.0003
0.0369
GO:0004930 G-protein coupled receptor activity
11none
 
yes
before_TSS
25
302
8.2
5.4
1.51
2.189
0.0285
0.0837
GO:0005667
12none
yes
 
after_TSS
25
495
5
2.6
1.92
3.458
0.0005
0.0181
GO:0007186 G-protein coupled receptor protein signaling pathway
13none
yes
 
before_TSS
24
283
8.4
3.7
2.28
4.284
0
0.0067
GO:0001584 rhodopsin-like receptor activity
14none
yes
 
after_TSS
24
357
6.7
2.6
2.56
4.927
0
0.0003
GO:0004930 G-protein coupled receptor activity
15none
 
yes
at_TSS
23
288
7.9
4.2
1.88
3.184
0.0014
0.0759
GO:0005794
16none
 
yes
at_TSS
23
301
7.6
4.2
1.79
2.957
0.0031
0.027
GO:0007399 nervous system development
17none
 
yes
before_TSS
22
220
10
5.4
1.83
2.997
0.0027
0.0498
GO:0051276 chromosome organization and biogenesis
18none
 
yes
before_TSS
22
208
10.5
5.4
1.93
3.282
0.001
0.0221
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
19none
 
yes
before_TSS
20
179
11.1
5.4
2.04
3.395
0.0006
0.0156
GO:0006325 establishment and/or maintenance of chromatin architecture
20none
 
yes
before_TSS
20
188
10.6
5.4
1.95
3.155
0.0016
0.0293
GO:0006323 DNA packaging
21none
 
yes
before_TSS
20
191
10.4
5.4
1.92
3.078
0.002
0.0693
GO:0006357 regulation of transcription from RNA polymerase II promoter
22none
 
yes
at_TSS
20
242
8.2
4.2
1.94
3.13
0.0017
0.0581
GO:0005856
23none
 
yes
after_TSS
19
121
15.7
8
1.94
3.086
0.002
0.0436
GO:0006333 chromatin assembly or disassembly
24none
 
 
before_TSS
18
33
54.5
24.3
2.24
4.046
0
0.0095
GO:0050876 reproductive physiological process
25none
 
 
before_TSS
18
33
54.5
24.3
2.24
4.046
0
0.0095
GO:0048609 reproductive organismal physiological process
26none
 
yes
after_TSS
18
128
14
8
1.73
2.491
0.0127
0.0971
GO:0007389 pattern specification
27none
 
yes
before_TSS
18
121
14.8
5.4
2.72
4.587
0
0.0001
GO:0006333 chromatin assembly or disassembly
28none
 
yes
before_TSS
17
86
19.7
5.4
3.62
5.866
0
0
GO:0006334 nucleosome assembly
29none
 
yes
before_TSS
17
123
13.8
5.4
2.53
4.107
0
0.0018
GO:0006461 protein complex assembly
30none
 
yes
before_TSS
17
170
10
5.4
1.83
2.629
0.0085
0.0847
GO:0009790 embryonic development
31none
 
yes
after_TSS
17
95
17.8
8
2.21
3.518
0.0004
0.0113
GO:0031497 chromatin assembly
32none
 
yes
before_TSS
17
157
10.8
5.4
1.98
2.985
0.0028
0.0691
GO:0007167 enzyme linked receptor protein signaling pathway
33none
 
yes
after_TSS
17
78
21.7
8
2.69
4.453
0
0.0002
GO:0000786
34none
 
yes
before_TSS
17
95
17.8
5.4
3.28
5.361
0
0
GO:0031497 chromatin assembly
35none
 
 
at_TSS
16
57
28
10.4
2.68
4.35
0
0.0024
GO:0016051 carbohydrate biosynthesis
36none
 
yes
after_TSS
16
86
18.6
8
2.3
3.589
0.0003
0.0086
GO:0006334 nucleosome assembly
37none
 
yes
before_TSS
15
78
19.2
5.4
3.52
5.375
0
0
GO:0000786
38none
 
yes
at_TSS
14
131
10.6
4.2
2.51
3.675
0.0002
0.087
GO:0008289 lipid binding
39none
 
yes
before_TSS
14
99
14.1
5.4
2.59
3.822
0.0001
0.008
GO:0007517 muscle development
40none
 
yes
before_TSS
14
88
15.9
5.4
2.91
4.335
0
0.0008
GO:0005694
41none
 
 
after_TSS
14
33
42.4
19.5
2.17
3.324
0.0008
0.0649
GO:0016526 G-protein coupled receptor activity, unknown ligand
42none
 
yes
after_TSS
12
54
22.2
8
2.74
3.817
0.0001
0.0164
GO:0005882
43none
 
yes
at_TSS
12
99
12.1
4.2
2.85
3.901
0
0.0087
GO:0007517 muscle development
44none
 
yes
before_TSS
11
86
12.7
5.4
2.34
3.007
0.0026
0.0965
GO:0045893 positive regulation of transcription, DNA-dependent
45none
 
yes
before_TSS
11
73
15
5.4
2.76
3.628
0.0002
0.0348
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
46none
 
yes
before_TSS
11
85
12.9
5.4
2.37
3.05
0.0022
0.0697
GO:0009792 embryonic development (sensu Metazoa)
47MIT_055NFAT
 
 
before_TSS
54
852
6.3
3.6
1.73
4.316
0
0.098
GO:0048513 organ development
48TF_AHR
 
 
after_TSS
24
220
10.9
4.1
2.59
5.01
0
0.0004
GO:0051276 chromosome organization and biogenesis
49TF_AHR
 
 
after_TSS
24
208
11.5
4.1
2.74
5.325
0
0
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
50TF_AHR
 
 
after_TSS
21
179
11.7
4.1
2.79
5.064
0
0.0003
GO:0006325 establishment and/or maintenance of chromatin architecture
51TF_AHR
 
 
after_TSS
21
188
11.1
4.1
2.66
4.805
0
0.0011
GO:0006323 DNA packaging
52TF_AHR
 
 
before_TSS
19
208
9.1
3.9
2.32
3.903
0
0.0418
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
53TF_AHR
 
 
before_TSS
18
86
20.9
3.9
5.33
8.15
0
0
GO:0006334 nucleosome assembly
54TF_AHR
 
 
before_TSS
18
95
18.9
3.9
4.82
7.57
0
0
GO:0031497 chromatin assembly
55TF_AHR
 
 
before_TSS
18
121
14.8
3.9
3.79
6.234
0
0
GO:0006333 chromatin assembly or disassembly
56TF_AHR
 
 
before_TSS
18
179
10
3.9
2.56
4.255
0
0.0107
GO:0006325 establishment and/or maintenance of chromatin architecture
57TF_AHR
 
 
before_TSS
18
123
14.6
3.9
3.72
6.147
0
0
GO:0006461 protein complex assembly
58TF_AHR
 
 
before_TSS
18
188
9.5
3.9
2.43
4.02
0
0.0254
GO:0006323 DNA packaging
59TF_AHR
 
 
after_TSS
18
121
14.8
4.1
3.54
5.887
0
0
GO:0006333 chromatin assembly or disassembly
60TF_AHR
 
 
after_TSS
17
86
19.7
4.1
4.7
7.226
0
0
GO:0006334 nucleosome assembly
61TF_AHR
 
 
after_TSS
17
123
13.8
4.1
3.29
5.349
0
0
GO:0006461 protein complex assembly
62TF_AHR
 
 
after_TSS
17
95
17.8
4.1
4.26
6.683
0
0
GO:0031497 chromatin assembly
63TF_AHR
 
 
after_TSS
17
78
21.7
4.1
5.19
7.775
0
0
GO:0000786
64TF_AHR
 
 
before_TSS
16
78
20.5
3.9
5.22
7.568
0
0
GO:0000786
65TF_AHR
 
 
before_TSS
14
88
15.9
3.9
4.05
5.81
0
0
GO:0005694
66TF_AHR
 
 
after_TSS
14
88
15.9
4.1
3.79
5.498
0
0
GO:0005694
67TF_AP2
 
 
before_TSS
10
75
13.3
3
4.32
5.152
0
0.0111
GO:0045595 regulation of cell differentiation
68TF_AP2A
 
 
before_TSS
47
852
5.5
2.8
1.95
4.937
0
0.0114
GO:0048513 organ development
69TF_ARNT
 
 
at_TSS
11
205
5.3
1.4
3.73
4.765
0
0.0163
GO:0044262 cellular carbohydrate metabolism
70TF_ATF1
 
 
before_TSS
13
123
10.5
3.1
3.33
4.715
0
0.0012
GO:0006461 protein complex assembly
71TF_ATF1
 
 
at_TSS
12
205
5.8
1.8
3.1
4.216
0
0.0895
GO:0044262 cellular carbohydrate metabolism
72TF_ATF1
 
 
before_TSS
11
95
11.5
3.1
3.65
4.703
0
0.001
GO:0031497 chromatin assembly
73TF_ATF1
 
 
before_TSS
11
78
14.1
3.1
4.45
5.536
0
0
GO:0000786
74TF_ATF1
 
 
before_TSS
11
86
12.7
3.1
4.04
5.117
0
0.0001
GO:0006334 nucleosome assembly
75TF_ATF1
 
 
before_TSS
10
88
11.3
3.1
3.59
4.409
0
0.0045
GO:0005694
76TF_ATF6
 
 
at_TSS
11
205
5.3
1.4
3.75
4.788
0
0.0242
GO:0044262 cellular carbohydrate metabolism
77TF_CREB
 
 
at_TSS
12
205
5.8
1.7
3.34
4.515
0
0.0342
GO:0044262 cellular carbohydrate metabolism
78TF_CREB
 
 
before_TSS
11
88
12.5
3.1
3.9
4.977
0
0.0003
GO:0005694
79TF_CREB
 
 
before_TSS
11
123
8.9
3.1
2.79
3.64
0.0002
0.0927
GO:0006461 protein complex assembly
80TF_CREB
 
 
before_TSS
10
86
11.6
3.1
3.63
4.459
0
0.0029
GO:0006334 nucleosome assembly
81TF_CREB
 
 
before_TSS
10
95
10.5
3.1
3.29
4.075
0
0.0156
GO:0031497 chromatin assembly
82TF_E2F
 
 
after_TSS
13
220
5.9
1.5
3.8
5.272
0
0.0001
GO:0051276 chromosome organization and biogenesis
83TF_E2F
 
 
after_TSS
13
208
6.2
1.5
4.02
5.525
0
0
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
84TF_E2F
 
 
after_TSS
12
121
9.9
1.5
6.38
7.477
0
0
GO:0006333 chromatin assembly or disassembly
85TF_E2F
 
 
after_TSS
12
86
13.9
1.5
8.98
9.331
0
0
GO:0006334 nucleosome assembly
86TF_E2F
 
 
after_TSS
12
179
6.7
1.5
4.31
5.613
0
0
GO:0006325 establishment and/or maintenance of chromatin architecture
87TF_E2F
 
 
after_TSS
12
95
12.6
1.5
8.13
8.765
0
0
GO:0031497 chromatin assembly
88TF_E2F
 
 
after_TSS
12
188
6.3
1.5
4.1
5.396
0
0
GO:0006323 DNA packaging
89TF_E2F
 
 
after_TSS
12
123
9.7
1.5
6.28
7.394
0
0
GO:0006461 protein complex assembly
90TF_E2F
 
 
after_TSS
10
78
12.8
1.5
8.25
8.072
0
0
GO:0000786
91TF_MAF
 
 
before_TSS
17
330
5.1
1.9
2.68
4.344
0
0.0431
GO:0051243 negative regulation of cellular physiological process
92TF_PAX4
 
 
before_TSS
18
220
8.1
1.9
4.17
6.723
0
0
GO:0051276 chromosome organization and biogenesis
93TF_PAX4
 
 
before_TSS
17
188
9
1.9
4.61
7.065
0
0
GO:0006323 DNA packaging
94TF_PAX4
 
 
before_TSS
17
208
8.1
1.9
4.17
6.524
0
0
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
95TF_PAX4
 
 
before_TSS
16
179
8.9
1.9
4.56
6.79
0
0
GO:0006325 establishment and/or maintenance of chromatin architecture
96TF_PAX4
 
 
before_TSS
16
121
13.2
1.9
6.75
8.987
0
0
GO:0006333 chromatin assembly or disassembly
97TF_PAX4
 
 
before_TSS
16
95
16.8
1.9
8.6
10.51
0
0
GO:0031497 chromatin assembly
98TF_PAX4
 
 
before_TSS
15
86
17.4
1.9
8.9
10.399
0
0
GO:0006334 nucleosome assembly
99TF_PAX4
 
 
before_TSS
15
78
19.2
1.9
9.82
11.044
0
0
GO:0000786
100TF_PAX4
 
 
before_TSS
15
123
12.1
1.9
6.22
8.235
0
0
GO:0006461 protein complex assembly
101TF_PAX4
 
 
before_TSS
14
88
15.9
1.9
8.12
9.479
0
0
GO:0005694
102TF_SP1
 
 
before_TSS
22
208
10.5
2.8
3.75
6.821
0
0
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
103TF_SP1
 
 
before_TSS
22
220
10
2.8
3.54
6.497
0
0
GO:0051276 chromosome organization and biogenesis
104TF_SP1
 
 
before_TSS
21
188
11.1
2.8
3.96
6.975
0
0
GO:0006323 DNA packaging
105TF_SP1
 
 
before_TSS
20
179
11.1
2.8
3.96
6.806
0
0
GO:0006325 establishment and/or maintenance of chromatin architecture
106TF_SP1
 
 
before_TSS
20
123
16.2
2.8
5.77
9.055
0
0
GO:0006461 protein complex assembly
107TF_SP1
 
 
before_TSS
19
95
20
2.8
7.09
10.16
0
0
GO:0031497 chromatin assembly
108TF_SP1
 
 
before_TSS
19
86
22
2.8
7.84
10.84
0
0
GO:0006334 nucleosome assembly
109TF_SP1
 
 
before_TSS
19
121
15.7
2.8
5.57
8.608
0
0
GO:0006333 chromatin assembly or disassembly
110TF_SP1
 
 
before_TSS
18
78
23
2.8
8.19
10.847
0
0
GO:0000786
111TF_SP1
 
 
before_TSS
14
88
15.9
2.8
5.64
7.448
0
0
GO:0005694
112TF_SP1
yes
 
at_TSS
10
131
7.6
1.8
4.21
5.028
0
0.0214
GO:0008289 lipid binding
113TF_SREBP
 
 
before_TSS
19
268
7
2.7
2.62
4.479
0
0.054
GO:0006807 nitrogen compound metabolism
114TF_STAF
 
 
before_TSS
24
427
5.6
1.8
2.97
5.757
0
0
GO:0006259 DNA metabolism
115TF_STAF
 
 
before_TSS
22
208
10.5
1.8
5.59
9.272
0
0
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
116TF_STAF
 
 
before_TSS
22
220
10
1.8
5.28
8.907
0
0
GO:0051276 chromosome organization and biogenesis
117TF_STAF
 
 
before_TSS
20
188
10.6
1.8
5.62
8.87
0
0
GO:0006323 DNA packaging
118TF_STAF
 
 
before_TSS
20
179
11.1
1.8
5.9
9.181
0
0
GO:0006325 establishment and/or maintenance of chromatin architecture
119TF_STAF
 
 
before_TSS
18
121
14.8
1.8
7.86
10.535
0
0
GO:0006333 chromatin assembly or disassembly
120TF_STAF
 
 
before_TSS
17
123
13.8
1.8
7.3
9.759
0
0
GO:0006461 protein complex assembly
121TF_STAF
 
 
before_TSS
16
78
20.5
1.8
10.84
12.108
0
0
GO:0000786
122TF_STAF
 
 
before_TSS
16
86
18.6
1.8
9.83
11.415
0
0
GO:0006334 nucleosome assembly
123TF_STAF
 
 
before_TSS
16
95
16.8
1.8
8.9
10.736
0
0
GO:0031497 chromatin assembly
124TF_STAF
 
 
before_TSS
15
88
17
1.8
9
10.471
0
0
GO:0005694
125TF_TAL1
 
 
before_TSS
12
177
6.7
1.9
3.53
4.752
0
0.0435
GO:0008237 metallopeptidase activity