Gene Ontology terms for targets of TF

CisView Mouse (mm6, March 2005)

Main Gene Ontology terms for targets of TF_ATF6

No.	GO annotation	Total genes with GO	Location	Max no. of genes with TF_ATF6	TF_ATF6 alone	In pair with
1	GO:0016070 RNA metabolism	342	at_TSS,after_TSS	134	yes	TF_AHR,
2	GO:0003700 transcription factor activity	719	before_TSS	125	yes
3	GO:0009653 morphogenesis	811	before_TSS	124	yes
4	GO:0009887 organ morphogenesis	674	before_TSS	112	yes
5	GO:0006396 RNA processing	273	at_TSS,after_TSS	106	yes	TF_AHR, TF_ELK,
6	GO:0008104 protein localization	508	at_TSS	98	yes	many
7	GO:0045184 establishment of protein localization	492	at_TSS	94	yes	many
8	GO:0015031 protein transport	476	at_TSS	91	yes	many
9	GO:0046907 intracellular transport	478	at_TSS	84		many
10	GO:0030154 cell differentiation	538	before_TSS	84	yes	TF_COMP,
11	GO:0016043 cell organization and biogenesis	839	after_TSS	81		TF_ATF1, TF_CREB,
12	GO:0009059 macromolecule biosynthesis	472	at_TSS,after_TSS	80		TF_ELK, MIT_006SP1,
13	GO:0006259 DNA metabolism	427	after_TSS	72	yes	many
14	GO:0006996 organelle organization and biogenesis	645	after_TSS	70		many
15	GO:0006886 intracellular protein transport	350	at_TSS	67	yes	many
16	GO:0007049 cell cycle	443	before_TSS	61		TF_SP1, TF_RFX, MIT_006SP1,
17	GO:0007399 nervous system development	301	before_TSS	61	yes
18	GO:0004386 helicase activity	108	at_TSS,after_TSS	57	yes	TF_GABP, TF_ELK,
19	GO:0006412 protein biosynthesis	421	after_TSS	55		TF_ELK,
20	GO:0051243 negative regulation of cellular physiological process	330	before_TSS	54	yes
21	GO:0043118 negative regulation of physiological process	342	before_TSS	54	yes
22	GO:0043037 translation	128	at_TSS	54	yes	MIT_101, TF_NFY,
23	GO:0051276 chromosome organization and biogenesis	220	after_TSS	53	yes	many
24	GO:0009058 biosynthesis	878	after_TSS	53		TF_E2F,
25	GO:0003723 RNA binding	354	at_TSS,after_TSS	53	yes	TF_AHR, TF_ARNT,
26	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)	208	after_TSS	52	yes	many
27	GO:0008565 protein transporter activity	120	at_TSS	50	yes	many
28	GO:0008026 ATP-dependent helicase activity	86	at_TSS,after_TSS	48	yes	TF_GABP, TF_ELK,
29	GO:0044249 cellular biosynthesis	776	after_TSS	48		TF_E2F,
30	GO:0016853 isomerase activity	118	at_TSS	48	yes
31	GO:0006325 establishment and/or maintenance of chromatin architecture	179	at_TSS,after_TSS	46	yes	many
32	GO:0006323 DNA packaging	188	after_TSS	46	yes	many
33	GO:0006512 ubiquitin cycle	390	at_TSS,before_TSS	43		TF_AP2, TF_ELK, TF_AP2A,
34	GO:0016887 ATPase activity	280	after_TSS	42		TF_GABP, TF_ELK,
35	GO:0045182 translation regulator activity	90	at_TSS,after_TSS	42	yes	many
36	GO:0008135 translation factor activity, nucleic acid binding	86	at_TSS,after_TSS	41	yes	many
37	GO:0007610 behavior	229	before_TSS	40	yes
38	GO:0006399 tRNA metabolism	86	at_TSS	39	yes
39	GO:0003743 translation initiation factor activity	53	at_TSS,before_TSS,after_TSS	37	yes	many
40	GO:0042623 ATPase activity, coupled	256	after_TSS	37		TF_ELK,
41	GO:0006366 transcription from RNA polymerase II promoter	231	before_TSS	37	yes	TF_AP2, TF_SP1,
42	GO:0006333 chromatin assembly or disassembly	121	before_TSS,after_TSS	36	yes	many
43	GO:0009790 embryonic development	170	before_TSS	36	yes
44	GO:0007626 locomotory behavior	187	before_TSS	33	yes
45	GO:0048468 cell development	162	before_TSS	33	yes
46	GO:0006461 protein complex assembly	123	after_TSS	32	yes	many
47	GO:0007028 cytoplasm organization and biogenesis	82	at_TSS	32	yes
48	GO:0007389 pattern specification	128	after_TSS	31	yes
49	GO:0031497 chromatin assembly	95	before_TSS,after_TSS	31	yes	many
50	GO:0006334 nucleosome assembly	86	after_TSS	31	yes	many
51	GO:0042254 ribosome biogenesis and assembly	74	at_TSS	30	yes	TF_AHR,
52	GO:0040011 locomotion	165	before_TSS	30	yes
53	GO:0030182 neuron differentiation	137	before_TSS	30	yes
54	GO:0006928 cell motility	162	before_TSS	29	yes
55	GO:0009892 negative regulation of metabolism	149	before_TSS	29	yes
56	GO:0007046 ribosome biogenesis	67	at_TSS	28	yes	TF_AHR,
57	GO:0031324 negative regulation of cellular metabolism	132	before_TSS	27	yes
58	GO:0006357 regulation of transcription from RNA polymerase II promoter	191	before_TSS	26		TF_AP2,
59	GO:0003735 structural constituent of ribosome	172	after_TSS	25	yes
60	GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism	121	before_TSS	25	yes
61	GO:0016481 negative regulation of transcription	115	before_TSS	24	yes
62	GO:0000904 cellular morphogenesis during differentiation	107	before_TSS	23	yes
63	GO:0006413 translational initiation	36	at_TSS,before_TSS	22	yes	many
64	GO:0048666 neuron development	108	before_TSS	22	yes
65	GO:0031175 neurite morphogenesis	96	before_TSS	21	yes
66	GO:0048667 neuron morphogensis during differentiation	96	before_TSS	21	yes
67	GO:0046903 secretion	123	at_TSS	21		MIT_003ELK, TF_GABP, TF_ELK,
68	GO:0008134 transcription factor binding	110	before_TSS	21	yes
69	GO:0007409 axonogenesis	81	before_TSS	20	yes
70	GO:0008033 tRNA processing	32	at_TSS,after_TSS	20	yes
71	GO:0006913 nucleocytoplasmic transport	70	at_TSS	19	yes
72	GO:0007417 central nervous system development	76	before_TSS	19	yes
73	GO:0016051 carbohydrate biosynthesis	57	at_TSS	19	yes	many
74	GO:0003712 transcription cofactor activity	94	before_TSS	19	yes
75	GO:0045045 secretory pathway	101	at_TSS	18		MIT_003ELK, TF_GABP, TF_ELK,
76	GO:0051169 nuclear transport	63	at_TSS	18	yes
77	GO:0009792 embryonic development (sensu Metazoa)	85	before_TSS	18	yes
78	GO:0016071 mRNA metabolism	202	after_TSS	17		TF_AHR, TF_AP2A,
79	GO:0007420 brain development	63	before_TSS	17	yes
80	GO:0006397 mRNA processing	189	at_TSS,after_TSS	16		TF_AHR, TF_PAX3,
81	GO:0008380 RNA splicing	154	after_TSS	15		TF_AHR,
82	GO:0035295 tube development	61	before_TSS	15	yes
83	GO:0000398 nuclear mRNA splicing, via spliceosome	149	after_TSS	14		TF_AHR,
84	GO:0044262 cellular carbohydrate metabolism	205	at_TSS	14		MIT_101, TF_AP4,
85	GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	149	after_TSS	14		TF_AHR,
86	GO:0016564 transcriptional repressor activity	64	before_TSS	14	yes
87	GO:0051168 nuclear export	26	at_TSS	14	yes
88	GO:0006457 protein folding	163	at_TSS	14		MIT_001NRF1, MIT_022,
89	GO:0000375 RNA splicing, via transesterification reactions	149	after_TSS	14		TF_AHR,
90	GO:0008168 methyltransferase activity	98	after_TSS	14		MIT_101, TF_GABP,
91	GO:0016741 transferase activity, transferring one-carbon groups	101	after_TSS	14		MIT_101, TF_GABP,
92	GO:0000279 M phase	122	at_TSS	14		many
93	GO:0006974 response to DNA damage stimulus	156	after_TSS	13		TF_ELK, MIT_035MYOD,
94	GO:0016859 cis-trans isomerase activity	31	after_TSS	13	yes
95	GO:0000278 mitotic cell cycle	135	at_TSS	13		MIT_001NRF1,
96	GO:0016192 vesicle-mediated transport	228	at_TSS	13		TF_GABP,
97	GO:0003755 peptidyl-prolyl cis-trans isomerase activity	30	after_TSS	12	yes
98	GO:0016563 transcriptional activator activity	53	before_TSS	12	yes
99	GO:0051301 cell division	134	at_TSS	12		MIT_001NRF1,

Pairs of TF_ATF6 binding sites with other TFBS

No.	TFBS	Location	Total GO-s	Main GO annotation	N pairs for main GO	Total genes for main GO
1	TF_AHR	at_TSS,before_TSS,after_TSS	21	GO:0006259 DNA metabolism	72	427
2	TF_ELK	at_TSS,before_TSS,after_TSS	18	GO:0046907 intracellular transport	84	478
3	MIT_001NRF1	at_TSS,after_TSS	18	GO:0000279 M phase	14	122
4	TF_GABP	at_TSS,after_TSS	14	GO:0008104 protein localization	64	508
5	MIT_006SP1	at_TSS,before_TSS,after_TSS	12	GO:0008104 protein localization	88	508
6	TF_CREB	before_TSS,after_TSS	12	GO:0016043 cell organization and biogenesis	71	839
7	TF_ATF1	after_TSS	11	GO:0016043 cell organization and biogenesis	81	839
8	ADD_LRH	after_TSS	9	GO:0006996 organelle organization and biogenesis	43	645
9	TF_NF1	before_TSS,after_TSS	9	GO:0006259 DNA metabolism	29	427
10	TF_SP1	at_TSS,before_TSS,after_TSS	9	GO:0008104 protein localization	98	508
11	MIT_152	after_TSS	8	GO:0051276 chromosome organization and biogenesis	11	220
12	MIT_003ELK	at_TSS	7	GO:0008104 protein localization	38	508
13	TF_ETS	at_TSS	6	GO:0046907 intracellular transport	47	478
14	TF_PAX4	after_TSS	6	GO:0006461 protein complex assembly	13	123
15	TF_TAXCREB1	after_TSS	6	GO:0006333 chromatin assembly or disassembly	11	121
16	MIT_019	at_TSS,after_TSS	6	GO:0006996 organelle organization and biogenesis	36	645
17	MIT_022	at_TSS	5	GO:0006457 protein folding	13	163
18	MIT_101	at_TSS,after_TSS	4	GO:0044262 cellular carbohydrate metabolism	14	205
19	TF_AP2	at_TSS,before_TSS	4	GO:0006512 ubiquitin cycle	43	390
20	TF_E2F	at_TSS,after_TSS	3	GO:0009058 biosynthesis	53	878
21	TF_ARNT	at_TSS,before_TSS,after_TSS	3	GO:0003723 RNA binding	33	354
22	TF_AP2A	at_TSS,after_TSS	3	GO:0006512 ubiquitin cycle	42	390
23	MIT_041MEIS	after_TSS	2	GO:0006323 DNA packaging	10	188
24	TF_NFY	at_TSS	2	GO:0043037 translation	17	128
25	TF_RFX	at_TSS,before_TSS	2	GO:0007049 cell cycle	40	443
26	MIT_012MYOD	at_TSS	2	GO:0019318 hexose metabolism	10	99
27	TF_HTF	before_TSS	2	GO:0003743 translation initiation factor activity	11	53
28	TF_STAT	after_TSS	1	GO:0006461 protein complex assembly	10	123
29	TF_ATF6	after_TSS	1	GO:0031497 chromatin assembly	10	95
30	MIT_045	after_TSS	1	GO:0006333 chromatin assembly or disassembly	14	121
31	MIT_140	at_TSS	1	GO:0008565 protein transporter activity	11	120
32	TF_EGR1	at_TSS	1	GO:0000279 M phase	12	122
33	TF_COMP	before_TSS	1	GO:0030154 cell differentiation	34	538
34	MIT_031	at_TSS	1	GO:0000910 cytokinesis	10	125
35	MIT_035MYOD	after_TSS	1	GO:0006974 response to DNA damage stimulus	13	156
36	TF_PAX3	at_TSS	1	GO:0006397 mRNA processing	10	189
37	TF_PBX	at_TSS	1	GO:0006325 establishment and/or maintenance of chromatin architecture	12	179
38	TF_AP4	at_TSS	1	GO:0044262 cellular carbohydrate metabolism	11	205

Details on Gene Ontology terms for targets of TF_ATF6

Total number of genes = 12103

No.	In pair with	Multi- ple	Conser- ved	Location	Frequency in list	U-clusters in list	Genes with TFBS in list, %	Genes with TFBS total, %	Ratio	z	p	FDR	GO annotation
1	none			at_TSS	134	342	39.1	25.3	1.54	5.939	0	0	GO:0016070 RNA metabolism
2	none		yes	before_TSS	125	719	17.3	10	1.72	6.708	0	0	GO:0003700 transcription factor activity
3	none		yes	before_TSS	124	811	15.2	10	1.51	5.101	0	0	GO:0009653 morphogenesis
4	none		yes	before_TSS	112	674	16.6	10	1.64	5.8	0	0	GO:0009887 organ morphogenesis
5	none			at_TSS	106	273	38.8	25.3	1.52	5.155	0	0	GO:0006396 RNA processing
6	none		yes	before_TSS	84	538	15.6	10	1.54	4.36	0	0.0005	GO:0030154 cell differentiation
7	none		yes	after_TSS	78	302	25.8	15	1.71	5.296	0	0	GO:0005667
8	none		yes	at_TSS	64	322	19.8	13.1	1.51	3.649	0.0002	0.0481	GO:0005783
9	none		yes	before_TSS	61	301	20.2	10	2.01	5.943	0	0	GO:0007399 nervous system development
10	none		yes	at_TSS	60	302	19.8	13.1	1.51	3.527	0.0004	0.0043	GO:0005667
11	none		yes	at_TSS	59	288	20.4	13.1	1.56	3.757	0.0001	0.0314	GO:0005794
12	none			after_TSS	57	108	52.7	33.9	1.55	4.148	0	0.004	GO:0004386 helicase activity
13	none	yes		after_TSS	55	427	12.8	7.9	1.62	3.852	0.0001	0.0035	GO:0006259 DNA metabolism
14	none		yes	before_TSS	54	302	17.8	10	1.77	4.559	0	0	GO:0005667
15	none		yes	before_TSS	54	342	15.7	10	1.56	3.557	0.0003	0.0114	GO:0043118 negative regulation of physiological process
16	none			at_TSS	54	128	42.1	25.3	1.66	4.386	0	0.0006	GO:0043037 translation
17	none		yes	before_TSS	54	330	16.3	10	1.62	3.843	0.0001	0.0055	GO:0051243 negative regulation of cellular physiological process
18	none		yes	after_TSS	53	220	24	15	1.59	3.778	0.0001	0.0057	GO:0051276 chromosome organization and biogenesis
19	none		yes	after_TSS	52	208	25	15	1.65	4.041	0	0.0024	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
20	none			at_TSS	50	120	41.6	25.3	1.64	4.114	0	0.0071	GO:0008565 protein transporter activity
21	none	yes		at_TSS	48	508	9.4	4.8	1.94	4.916	0	0	GO:0008104 protein localization
22	none			after_TSS	48	86	55.8	33.9	1.64	4.294	0	0.0021	GO:0008026 ATP-dependent helicase activity
23	none	yes		at_TSS	48	492	9.7	4.8	2	5.158	0	0	GO:0045184 establishment of protein localization
24	none			at_TSS	48	118	40.6	25.3	1.6	3.831	0.0001	0.0233	GO:0016853 isomerase activity
25	none	yes		at_TSS	47	476	9.8	4.8	2.03	5.192	0	0	GO:0015031 protein transport
26	none		yes	after_TSS	46	188	24.4	15	1.62	3.633	0.0002	0.0093	GO:0006323 DNA packaging
27	none		yes	after_TSS	46	179	25.6	15	1.7	4.007	0	0.0032	GO:0006325 establishment and/or maintenance of chromatin architecture
28	none	yes		after_TSS	46	354	12.9	7.9	1.63	3.577	0.0003	0.0053	GO:0003723 RNA binding
29	none			at_TSS	45	108	41.6	25.3	1.64	3.901	0	0.0058	GO:0004386 helicase activity
30	none			at_TSS	42	90	46.6	25.3	1.83	4.652	0	0.0001	GO:0045182 translation regulator activity
31	none			at_TSS	41	86	47.6	25.3	1.87	4.762	0	0.0001	GO:0008135 translation factor activity, nucleic acid binding
32	none		yes	before_TSS	40	229	17.4	10	1.73	3.748	0.0001	0.0072	GO:0007610 behavior
33	none			at_TSS	39	86	45.3	25.3	1.78	4.265	0	0.0024	GO:0006399 tRNA metabolism
34	none	yes		at_TSS	38	350	10.8	4.8	2.23	5.296	0	0	GO:0006886 intracellular protein transport
35	none			before_TSS	37	53	69.8	44.9	1.55	3.641	0.0002	0.0496	GO:0003743 translation initiation factor activity
36	none		yes	before_TSS	37	231	16	10	1.58	3.026	0.0024	0.0533	GO:0006366 transcription from RNA polymerase II promoter
37	none		yes	before_TSS	36	170	21.1	10	2.1	4.839	0	0.0001	GO:0009790 embryonic development
38	none		yes	after_TSS	36	121	29.7	15	1.97	4.54	0	0.0002	GO:0006333 chromatin assembly or disassembly
39	none			at_TSS	35	86	40.6	25.3	1.6	3.27	0.001	0.0437	GO:0008026 ATP-dependent helicase activity
40	none		yes	before_TSS	33	187	17.6	10	1.75	3.463	0.0005	0.0217	GO:0007626 locomotory behavior
41	none		yes	before_TSS	33	162	20.3	10	2.02	4.379	0	0.0005	GO:0048468 cell development
42	none	yes		after_TSS	33	220	15	7.9	1.89	3.915	0	0.0027	GO:0051276 chromosome organization and biogenesis
43	none	yes		after_TSS	32	208	15.3	7.9	1.93	4.011	0	0.0017	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
44	none			at_TSS	32	82	39	25.3	1.53	2.844	0.0044	0.0815	GO:0007028 cytoplasm organization and biogenesis
45	none		yes	after_TSS	31	128	24.2	15	1.6	2.911	0.0036	0.0329	GO:0007389 pattern specification
46	none		yes	after_TSS	31	86	36	15	2.39	5.459	0	0	GO:0006334 nucleosome assembly
47	none		yes	after_TSS	31	95	32.6	15	2.16	4.806	0	0	GO:0031497 chromatin assembly
48	none	yes		after_TSS	30	188	15.9	7.9	2.01	4.103	0	0.001	GO:0006323 DNA packaging
49	none		yes	before_TSS	30	137	21.8	10	2.17	4.62	0	0.0002	GO:0030182 neuron differentiation
50	none	yes		after_TSS	30	179	16.7	7.9	2.11	4.403	0	0.0003	GO:0006325 establishment and/or maintenance of chromatin architecture
51	none			at_TSS	30	74	40.5	25.3	1.59	3.001	0.0026	0.0518	GO:0042254 ribosome biogenesis and assembly
52	none		yes	before_TSS	30	165	18.1	10	1.8	3.48	0.0005	0.0141	GO:0040011 locomotion
53	none		yes	after_TSS	29	78	37.1	15	2.46	5.478	0	0	GO:0000786
54	none		yes	before_TSS	29	149	19.4	10	1.93	3.827	0.0001	0.0043	GO:0009892 negative regulation of metabolism
55	none		yes	before_TSS	29	162	17.9	10	1.77	3.328	0.0008	0.0228	GO:0006928 cell motility
56	none			at_TSS	28	67	41.7	25.3	1.64	3.09	0.002	0.043	GO:0007046 ribosome biogenesis
57	none			at_TSS	27	53	50.9	25.3	2	4.281	0	0.0013	GO:0003743 translation initiation factor activity
58	none		yes	before_TSS	27	132	20.4	10	2.02	3.98	0	0.0042	GO:0031324 negative regulation of cellular metabolism
59	none	yes		after_TSS	26	183	14.2	7.9	1.79	3.165	0.0015	0.0378	GO:0030529
60	none	yes		after_TSS	25	123	20.3	7.9	2.56	5.112	0	0	GO:0006461 protein complex assembly
61	none		yes	before_TSS	25	121	20.6	10	2.04	3.885	0.0001	0.0053	GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
62	none	yes		after_TSS	25	172	14.5	7.9	1.83	3.227	0.0012	0.0381	GO:0003735 structural constituent of ribosome
63	none		yes	before_TSS	24	115	20.8	10	2.07	3.861	0.0001	0.0051	GO:0016481 negative regulation of transcription
64	none		yes	before_TSS	23	107	21.4	10	2.13	3.939	0	0.0037	GO:0000904 cellular morphogenesis during differentiation
65	none	yes		after_TSS	23	121	19	7.9	2.39	4.531	0	0.0001	GO:0006333 chromatin assembly or disassembly
66	none	yes		after_TSS	23	95	24.2	7.9	3.05	5.894	0	0	GO:0031497 chromatin assembly
67	none		yes	before_TSS	22	108	20.3	10	2.02	3.567	0.0003	0.0146	GO:0048666 neuron development
68	none			at_TSS	22	36	61.1	25.3	2.4	4.929	0	0.0003	GO:0006413 translational initiation
69	none		yes	before_TSS	21	96	21.8	10	2.17	3.853	0.0001	0.0053	GO:0031175 neurite morphogenesis
70	none		yes	before_TSS	21	110	19	10	1.89	3.153	0.0016	0.0537	GO:0008134 transcription factor binding
71	none		yes	before_TSS	21	96	21.8	10	2.17	3.853	0.0001	0.0053	GO:0048667 neuron morphogensis during differentiation
72	none	yes		after_TSS	21	78	26.9	7.9	3.39	6.226	0	0	GO:0000786
73	none	yes		after_TSS	21	86	24.4	7.9	3.07	5.677	0	0	GO:0006334 nucleosome assembly
74	none	yes		after_TSS	21	88	23.8	7.9	3	5.55	0	0	GO:0005694
75	none		yes	before_TSS	20	81	24.6	10	2.44	4.382	0	0.001	GO:0007409 axonogenesis
76	none			after_TSS	20	32	62.5	33.9	1.84	3.413	0.0006	0.0587	GO:0008033 tRNA processing
77	none		yes	at_TSS	19	70	27.1	13.1	2.07	3.49	0.0004	0.0589	GO:0006913 nucleocytoplasmic transport
78	none		yes	before_TSS	19	94	20.2	10	2	3.275	0.001	0.0552	GO:0003712 transcription cofactor activity
79	none		yes	before_TSS	19	76	25	10	2.48	4.333	0	0.0004	GO:0007417 central nervous system development
80	none			at_TSS	19	32	59.3	25.3	2.33	4.421	0	0.0035	GO:0008033 tRNA processing
81	none		yes	at_TSS	19	57	33.3	13.1	2.54	4.536	0	0.002	GO:0016051 carbohydrate biosynthesis
82	none		yes	at_TSS	18	63	28.5	13.1	2.18	3.647	0.0002	0.0485	GO:0051169 nuclear transport
83	none		yes	before_TSS	18	85	21.1	10	2.1	3.409	0.0006	0.034	GO:0009792 embryonic development (sensu Metazoa)
84	none		yes	before_TSS	17	63	26.9	10	2.67	4.468	0	0.0002	GO:0007420 brain development
85	none		yes	before_TSS	15	61	24.5	10	2.43	3.773	0.0001	0.0073	GO:0035295 tube development
86	none			at_TSS	14	26	53.8	25.3	2.12	3.335	0.0008	0.039	GO:0051168 nuclear export
87	none		yes	before_TSS	14	64	21.8	10	2.17	3.142	0.0016	0.0511	GO:0016564 transcriptional repressor activity
88	none	yes		after_TSS	13	58	22.4	7.9	2.82	4.09	0	0.0039	GO:0005730
89	none		yes	after_TSS	13	31	41.9	15	2.78	4.188	0	0.0103	GO:0016859 cis-trans isomerase activity
90	none		yes	before_TSS	12	53	22.6	10	2.24	3.044	0.0023	0.0949	GO:0016563 transcriptional activator activity
91	none		yes	after_TSS	12	30	40	15	2.65	3.823	0.0001	0.0482	GO:0003755 peptidyl-prolyl cis-trans isomerase activity
92	none	yes		at_TSS	10	78	12.8	4.8	2.63	3.281	0.001	0.0473	GO:0005764
93	none		yes	before_TSS	10	37	27	10	2.68	3.429	0.0006	0.0443	GO:0035239 tube morphogenesis
94	ADD_LRH			after_TSS	43	645	6.6	3.7	1.77	4.004	0	0.0625	GO:0006996 organelle organization and biogenesis
95	ADD_LRH			after_TSS	25	220	11.3	3.7	3.02	5.996	0	0	GO:0051276 chromosome organization and biogenesis
96	ADD_LRH			after_TSS	23	208	11	3.7	2.94	5.593	0	0	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
97	ADD_LRH			after_TSS	21	179	11.7	3.7	3.12	5.661	0	0	GO:0006325 establishment and/or maintenance of chromatin architecture
98	ADD_LRH			after_TSS	21	88	23.8	3.7	6.36	9.965	0	0	GO:0005694
99	ADD_LRH			after_TSS	21	123	17	3.7	4.55	7.815	0	0	GO:0006461 protein complex assembly
100	ADD_LRH			after_TSS	21	188	11.1	3.7	2.97	5.395	0	0	GO:0006323 DNA packaging
101	ADD_LRH			after_TSS	20	121	16.5	3.7	4.4	7.434	0	0	GO:0006333 chromatin assembly or disassembly
102	ADD_LRH			after_TSS	20	86	23.2	3.7	6.19	9.552	0	0	GO:0006334 nucleosome assembly
103	ADD_LRH			after_TSS	20	95	21	3.7	5.61	8.909	0	0	GO:0031497 chromatin assembly
104	ADD_LRH			after_TSS	19	78	24.3	3.7	6.49	9.609	0	0	GO:0000786
105	ADD_LRH	yes		after_TSS	13	208	6.2	0.6	9.95	10.353	0	0	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
106	ADD_LRH	yes		after_TSS	13	179	7.2	0.6	11.56	11.32	0	0	GO:0006325 establishment and/or maintenance of chromatin architecture
107	ADD_LRH	yes		after_TSS	13	220	5.9	0.6	9.41	10.007	0	0	GO:0051276 chromosome organization and biogenesis
108	ADD_LRH	yes		after_TSS	13	188	6.9	0.6	11.01	10.997	0	0	GO:0006323 DNA packaging
109	ADD_LRH	yes		after_TSS	12	78	15.3	0.6	24.5	16.551	0	0	GO:0000786
110	ADD_LRH	yes		after_TSS	12	95	12.6	0.6	20.11	14.868	0	0	GO:0031497 chromatin assembly
111	ADD_LRH	yes		after_TSS	12	123	9.7	0.6	15.53	12.88	0	0	GO:0006461 protein complex assembly
112	ADD_LRH	yes		after_TSS	12	121	9.9	0.6	15.79	13	0	0	GO:0006333 chromatin assembly or disassembly
113	ADD_LRH	yes		after_TSS	12	86	13.9	0.6	22.22	15.699	0	0	GO:0006334 nucleosome assembly
114	ADD_LRH	yes		after_TSS	11	88	12.5	0.6	19.9	14.149	0	0	GO:0005694
115	MIT_001NRF1			at_TSS	14	163	8.5	2.4	3.54	5.158	0	0.0008	GO:0006457 protein folding
116	MIT_001NRF1			at_TSS	14	122	11.4	2.4	4.74	6.539	0	0	GO:0000279 M phase
117	MIT_001NRF1			at_TSS	13	90	14.4	2.4	5.96	7.448	0	0	GO:0045182 translation regulator activity
118	MIT_001NRF1			at_TSS	13	135	9.6	2.4	3.97	5.479	0	0.0006	GO:0000278 mitotic cell cycle
119	MIT_001NRF1			at_TSS	13	86	15.1	2.4	6.24	7.687	0	0	GO:0008135 translation factor activity, nucleic acid binding
120	MIT_001NRF1			at_TSS	12	134	8.9	2.4	3.69	4.948	0	0.0036	GO:0051301 cell division
121	MIT_001NRF1			after_TSS	11	220	5	0.6	8.06	8.355	0	0	GO:0051276 chromosome organization and biogenesis
122	MIT_001NRF1			after_TSS	11	188	5.8	0.6	9.44	9.211	0	0	GO:0006323 DNA packaging
123	MIT_001NRF1			after_TSS	11	78	14.1	0.6	22.75	15.222	0	0	GO:0000786
124	MIT_001NRF1			after_TSS	11	123	8.9	0.6	14.43	11.822	0	0	GO:0006461 protein complex assembly
125	MIT_001NRF1			after_TSS	11	86	12.7	0.6	20.64	14.433	0	0	GO:0006334 nucleosome assembly
126	MIT_001NRF1			at_TSS	11	125	8.8	2.4	3.63	4.664	0	0.0121	GO:0000910 cytokinesis
127	MIT_001NRF1			after_TSS	11	95	11.5	0.6	18.68	13.664	0	0	GO:0031497 chromatin assembly
128	MIT_001NRF1			after_TSS	11	179	6.1	0.6	9.91	9.49	0	0	GO:0006325 establishment and/or maintenance of chromatin architecture
129	MIT_001NRF1			at_TSS	11	106	10.3	2.4	4.28	5.353	0	0.0003	GO:0051082 unfolded protein binding
130	MIT_001NRF1			after_TSS	11	208	5.2	0.6	8.53	8.654	0	0	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
131	MIT_001NRF1			after_TSS	11	121	9	0.6	14.67	11.933	0	0	GO:0006333 chromatin assembly or disassembly
132	MIT_001NRF1			at_TSS	10	53	18.8	2.4	7.79	7.807	0	0	GO:0003743 translation initiation factor activity
133	MIT_001NRF1			at_TSS	10	89	11.2	2.4	4.64	5.43	0	0.0004	GO:0000087 M phase of mitotic cell cycle
134	MIT_003ELK			at_TSS	38	508	7.4	3.1	2.35	5.658	0	0	GO:0008104 protein localization
135	MIT_003ELK			at_TSS	36	492	7.3	3.1	2.3	5.354	0	0.0002	GO:0045184 establishment of protein localization
136	MIT_003ELK			at_TSS	36	476	7.5	3.1	2.38	5.575	0	0	GO:0015031 protein transport
137	MIT_003ELK			at_TSS	35	478	7.3	3.1	2.3	5.28	0	0.0003	GO:0046907 intracellular transport
138	MIT_003ELK			at_TSS	27	350	7.7	3.1	2.43	4.918	0	0.002	GO:0006886 intracellular protein transport
139	MIT_003ELK			at_TSS	16	123	13	3.1	4.09	6.254	0	0	GO:0046903 secretion
140	MIT_003ELK			at_TSS	14	101	13.8	3.1	4.36	6.154	0	0	GO:0045045 secretory pathway
141	MIT_006SP1			at_TSS	88	508	17.3	10.8	1.59	4.762	0	0.0029	GO:0008104 protein localization
142	MIT_006SP1			at_TSS	85	492	17.2	10.8	1.58	4.65	0	0.0046	GO:0045184 establishment of protein localization
143	MIT_006SP1			at_TSS	82	476	17.2	10.8	1.58	4.535	0	0.0075	GO:0015031 protein transport
144	MIT_006SP1			at_TSS	80	472	16.9	10.8	1.55	4.317	0	0.0854	GO:0009059 macromolecule biosynthesis
145	MIT_006SP1			before_TSS	53	443	11.9	6.1	1.95	5.224	0	0.0005	GO:0007049 cell cycle
146	MIT_006SP1			at_TSS	19	57	33.3	10.8	3.06	5.455	0	0.001	GO:0016051 carbohydrate biosynthesis
147	MIT_006SP1	yes		at_TSS	14	90	15.5	5.2	2.95	4.382	0	0.0203	GO:0045182 translation regulator activity
148	MIT_006SP1	yes		at_TSS	14	86	16.2	5.2	3.08	4.584	0	0.0089	GO:0008135 translation factor activity, nucleic acid binding
149	MIT_006SP1			after_TSS	14	88	15.9	5.5	2.85	4.245	0	0.0129	GO:0005694
150	MIT_006SP1			after_TSS	12	78	15.3	5.5	2.76	3.792	0.0001	0.0922	GO:0000786
151	MIT_006SP1	yes		at_TSS	11	53	20.7	5.2	3.93	5.055	0	0.0031	GO:0003743 translation initiation factor activity
152	MIT_006SP1		yes	after_TSS	10	121	8.2	1.7	4.8	5.568	0	0.0001	GO:0006333 chromatin assembly or disassembly
153	MIT_006SP1	yes		at_TSS	10	36	27.7	5.2	5.26	6.051	0	0	GO:0006413 translational initiation
154	MIT_006SP1		yes	after_TSS	10	179	5.5	1.7	3.25	4.011	0	0.0746	GO:0006325 establishment and/or maintenance of chromatin architecture
155	MIT_012MYOD			at_TSS	10	101	9.9	2.5	3.92	4.752	0	0.087	GO:0005996 monosaccharide metabolism
156	MIT_012MYOD			at_TSS	10	99	10.1	2.5	4	4.832	0	0.0584	GO:0019318 hexose metabolism
157	MIT_018SREBP			at_TSS	12	78	15.3	0.9	16.47	13.312	0	0	GO:0005764
158	MIT_019			after_TSS	36	645	5.5	2.9	1.86	3.951	0	0.0764	GO:0006996 organelle organization and biogenesis
159	MIT_019			after_TSS	11	123	8.9	2.9	2.98	3.884	0.0001	0.0522	GO:0006461 protein complex assembly
160	MIT_019			after_TSS	11	86	12.7	2.9	4.26	5.342	0	0	GO:0006334 nucleosome assembly
161	MIT_019			after_TSS	11	121	9	2.9	3.03	3.948	0	0.041	GO:0006333 chromatin assembly or disassembly
162	MIT_019			after_TSS	11	88	12.5	2.9	4.16	5.244	0	0.0001	GO:0005694
163	MIT_019			after_TSS	11	95	11.5	2.9	3.86	4.921	0	0.0005	GO:0031497 chromatin assembly
164	MIT_019			at_TSS	10	90	11.1	2.6	4.16	4.987	0	0.0012	GO:0045182 translation regulator activity
165	MIT_022			at_TSS	13	163	7.9	1.9	4.02	5.524	0	0.0001	GO:0006457 protein folding
166	MIT_022			at_TSS	11	122	9	1.9	4.54	5.6	0	0	GO:0000279 M phase
167	MIT_022			at_TSS	10	90	11.1	1.9	5.6	6.234	0	0	GO:0045182 translation regulator activity
168	MIT_022			at_TSS	10	86	11.6	1.9	5.86	6.438	0	0	GO:0008135 translation factor activity, nucleic acid binding
169	MIT_022			at_TSS	10	106	9.4	1.9	4.75	5.526	0	0.0002	GO:0051082 unfolded protein binding
170	MIT_031			at_TSS	10	125	8	2.2	3.62	4.433	0	0.0308	GO:0000910 cytokinesis
171	MIT_035MYOD			after_TSS	13	156	8.3	2.5	3.26	4.606	0	0.0887	GO:0006974 response to DNA damage stimulus
172	MIT_041MEIS			after_TSS	10	179	5.5	1.8	3.08	3.819	0.0001	0.0793	GO:0006325 establishment and/or maintenance of chromatin architecture
173	MIT_041MEIS		yes	after_TSS	10	188	5.3	0.4	12.38	10.33	0	0	GO:0006323 DNA packaging
174	MIT_045			after_TSS	14	121	11.5	3.7	3.11	4.597	0	0.0025	GO:0006333 chromatin assembly or disassembly
175	MIT_045			after_TSS	10	88	11.3	3.7	3.06	3.812	0.0001	0.0783	GO:0005694
176	MIT_101			at_TSS	14	205	6.8	2.2	3.09	4.545	0	0.0339	GO:0044262 cellular carbohydrate metabolism
177	MIT_101			after_TSS	13	101	12.8	4.1	3.09	4.398	0	0.0944	GO:0016741 transferase activity, transferring one-carbon groups
178	MIT_101			after_TSS	13	98	13.2	4.1	3.18	4.528	0	0.0514	GO:0008168 methyltransferase activity
179	MIT_101			at_TSS	11	128	8.5	2.2	3.89	4.946	0	0.0032	GO:0043037 translation
180	MIT_140			at_TSS	11	120	9.1	2.6	3.48	4.5	0	0.0266	GO:0008565 protein transporter activity
181	MIT_152			after_TSS	11	86	12.7	0.7	16.64	12.812	0	0	GO:0006334 nucleosome assembly
182	MIT_152			after_TSS	11	88	12.5	0.7	16.26	12.648	0	0	GO:0005694
183	MIT_152			after_TSS	11	78	14.1	0.7	18.35	13.529	0	0	GO:0000786
184	MIT_152			after_TSS	11	123	8.9	0.7	11.63	10.435	0	0	GO:0006461 protein complex assembly
185	MIT_152			after_TSS	11	121	9	0.7	11.83	10.536	0	0	GO:0006333 chromatin assembly or disassembly
186	MIT_152			after_TSS	11	208	5.2	0.7	6.88	7.53	0	0	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
187	MIT_152			after_TSS	11	179	6.1	0.7	7.99	8.299	0	0	GO:0006325 establishment and/or maintenance of chromatin architecture
188	MIT_152			after_TSS	11	220	5	0.7	6.5	7.253	0	0	GO:0051276 chromosome organization and biogenesis
189	MIT_152			after_TSS	11	188	5.8	0.7	7.61	8.043	0	0	GO:0006323 DNA packaging
190	MIT_152			after_TSS	11	95	11.5	0.7	15.06	12.113	0	0	GO:0031497 chromatin assembly
191	TF_AHR			after_TSS	72	427	16.8	9.1	1.83	5.605	0	0	GO:0006259 DNA metabolism
192	TF_AHR			at_TSS	53	354	14.9	7.7	1.91	5.107	0	0.0004	GO:0003723 RNA binding
193	TF_AHR			after_TSS	45	220	20.4	9.1	2.23	5.851	0	0	GO:0051276 chromosome organization and biogenesis
194	TF_AHR			at_TSS	44	273	16.1	7.7	2.06	5.183	0	0.0009	GO:0006396 RNA processing
195	TF_AHR			after_TSS	44	208	21.1	9.1	2.3	6.039	0	0	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
196	TF_AHR			after_TSS	42	188	22.3	9.1	2.43	6.305	0	0	GO:0006323 DNA packaging
197	TF_AHR			after_TSS	41	179	22.9	9.1	2.49	6.413	0	0	GO:0006325 establishment and/or maintenance of chromatin architecture
198	TF_AHR			after_TSS	33	121	27.2	9.1	2.97	6.933	0	0	GO:0006333 chromatin assembly or disassembly
199	TF_AHR			after_TSS	32	123	26	9.1	2.83	6.505	0	0	GO:0006461 protein complex assembly
200	TF_AHR			after_TSS	28	95	29.4	9.1	3.21	6.882	0	0	GO:0031497 chromatin assembly
201	TF_AHR			after_TSS	27	86	31.3	9.1	3.42	7.165	0	0	GO:0006334 nucleosome assembly
202	TF_AHR			after_TSS	26	88	29.5	9.1	3.22	6.646	0	0	GO:0005694
203	TF_AHR			after_TSS	24	78	30.7	9.1	3.35	6.63	0	0	GO:0000786
204	TF_AHR			before_TSS	24	121	19.8	9.1	2.16	4.084	0	0.0162	GO:0006333 chromatin assembly or disassembly
205	TF_AHR	yes		after_TSS	23	342	6.7	2.9	2.25	4.127	0	0.0882	GO:0016070 RNA metabolism
206	TF_AHR	yes		after_TSS	21	273	7.6	2.9	2.57	4.626	0	0.0123	GO:0006396 RNA processing
207	TF_AHR	yes		after_TSS	17	202	8.4	2.9	2.82	4.577	0	0.0101	GO:0016071 mRNA metabolism
208	TF_AHR	yes		after_TSS	16	189	8.4	2.9	2.83	4.465	0	0.0182	GO:0006397 mRNA processing
209	TF_AHR			at_TSS	16	74	21.6	7.7	2.77	4.447	0	0.0117	GO:0042254 ribosome biogenesis and assembly
210	TF_AHR			at_TSS	15	67	22.3	7.7	2.87	4.465	0	0.0111	GO:0007046 ribosome biogenesis
211	TF_AHR	yes		after_TSS	15	154	9.7	2.9	3.26	4.961	0	0.0023	GO:0008380 RNA splicing
212	TF_AHR	yes		after_TSS	14	149	9.3	2.9	3.15	4.63	0	0.0098	GO:0000398 nuclear mRNA splicing, via spliceosome
213	TF_AHR	yes		after_TSS	14	149	9.3	2.9	3.15	4.63	0	0.0098	GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
214	TF_AHR	yes		after_TSS	14	149	9.3	2.9	3.15	4.63	0	0.0098	GO:0000375 RNA splicing, via transesterification reactions
215	TF_AHR			before_TSS	11	34	32.3	9.1	3.52	4.689	0	0.0395	GO:0003714 transcription corepressor activity
216	TF_AP2			at_TSS	43	390	11	5.8	1.89	4.467	0	0.0214	GO:0006512 ubiquitin cycle
217	TF_AP2			before_TSS	29	231	12.5	5.9	2.11	4.285	0	0.0526	GO:0006366 transcription from RNA polymerase II promoter
218	TF_AP2			before_TSS	26	191	13.6	5.9	2.28	4.513	0	0.0306	GO:0006357 regulation of transcription from RNA polymerase II promoter
219	TF_AP2			after_TSS	16	53	30.1	8.7	3.43	5.508	0	0.0003	GO:0019866
220	TF_AP2			at_TSS	11	57	19.2	5.8	3.31	4.358	0	0.0472	GO:0016051 carbohydrate biosynthesis
221	TF_AP2A			at_TSS	42	390	10.7	5.8	1.85	4.247	0	0.0468	GO:0006512 ubiquitin cycle
222	TF_AP2A			after_TSS	15	53	28.3	9	3.14	4.917	0	0.0042	GO:0019866
223	TF_AP2A	yes		after_TSS	14	202	6.9	2.5	2.76	4.061	0	0.0812	GO:0016071 mRNA metabolism
224	TF_AP2A			at_TSS	12	57	21	5.8	3.61	4.925	0	0.0072	GO:0016051 carbohydrate biosynthesis
225	TF_AP4			at_TSS	11	205	5.3	1.4	3.75	4.788	0	0.0242	GO:0044262 cellular carbohydrate metabolism
226	TF_ARNT			at_TSS	33	354	9.3	4.5	2.06	4.426	0	0.0096	GO:0003723 RNA binding
227	TF_ARNT			before_TSS	10	36	27.7	6	4.59	5.482	0	0.0003	GO:0006413 translational initiation