CisView Mouse (mm6, March 2005)

Main Gene Ontology terms for targets of TF_CREB

No.GO annotation
Total
genes
with GO
Location
Max no. of
genes with
TF_CREB
TF_CREB alone
In pair
with
1GO:0003700 transcription factor activity
719
at_TSS,before_TSS
115
yes
MIT_024MAZ,
2GO:0006996 organelle organization and biogenesis
645
at_TSS,before_TSS,after_TSS
104
 
many
3GO:0008104 protein localization
508
at_TSS,before_TSS
94
 
many
4GO:0046907 intracellular transport
478
at_TSS
92
 
TF_GABP, TF_SP1, TF_ELK,
5GO:0045184 establishment of protein localization
492
at_TSS,before_TSS
90
 
many
6GO:0015031 protein transport
476
at_TSS,before_TSS
89
 
many
7GO:0030554 adenyl nucleotide binding
1036
before_TSS
89
 
ADD_LRH,
8GO:0005524 ATP binding
1011
before_TSS
87
 
ADD_LRH,
9GO:0006350 transcription
1461
at_TSS,before_TSS
84
yes
TF_SP1,
10GO:0016043 cell organization and biogenesis
839
before_TSS,after_TSS
83
 
many
11GO:0019222 regulation of metabolism
1541
at_TSS,before_TSS
81
yes
TF_SP1,
12GO:0031323 regulation of cellular metabolism
1510
at_TSS,before_TSS
81
yes
TF_SP1,
13GO:0006259 DNA metabolism
427
at_TSS,before_TSS,after_TSS
81
yes
many
14GO:0003723 RNA binding
354
at_TSS,before_TSS,after_TSS
81
yes
many
15GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
1420
at_TSS,before_TSS
80
yes
TF_SP1,
16GO:0045449 regulation of transcription
1410
at_TSS,before_TSS
80
yes
TF_SP1,
17GO:0003677 DNA binding
1509
before_TSS
79
 
TF_SP1,
18GO:0006351 transcription, DNA-dependent
1383
at_TSS,before_TSS
77
yes
TF_SP1,
19GO:0006355 regulation of transcription, DNA-dependent
1362
at_TSS,before_TSS
74
yes
TF_SP1,
20GO:0006461 protein complex assembly
123
at_TSS,before_TSS,after_TSS
67
yes
many
21GO:0006886 intracellular protein transport
350
at_TSS,before_TSS
67
 
many
22GO:0006333 chromatin assembly or disassembly
121
at_TSS,before_TSS,after_TSS
65
yes
many
23GO:0031497 chromatin assembly
95
at_TSS,before_TSS,after_TSS
60
yes
many
24GO:0007049 cell cycle
443
before_TSS
59
yes
TF_SP1, TF_RFX, MIT_006SP1,
25GO:0006334 nucleosome assembly
86
at_TSS,before_TSS,after_TSS
55
yes
many
26GO:0006412 protein biosynthesis
421
after_TSS
55
 
TF_ELK,
27GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
208
at_TSS,before_TSS,after_TSS
54
yes
many
28GO:0051276 chromosome organization and biogenesis
220
at_TSS,before_TSS,after_TSS
54
yes
many
29GO:0004386 helicase activity
108
at_TSS,after_TSS
54
yes
TF_GABP, TF_ELK, TF_E2F,
30GO:0006512 ubiquitin cycle
390
at_TSS
53
 
TF_AP2, TF_AP2A, MIT_020E4F1,
31GO:0030528 transcription regulator activity
941
at_TSS
53
yes
 
32GO:0006323 DNA packaging
188
at_TSS,before_TSS,after_TSS
52
yes
many
33GO:0006325 establishment and/or maintenance of chromatin architecture
179
at_TSS,before_TSS,after_TSS
50
yes
many
34GO:0016741 transferase activity, transferring one-carbon groups
101
at_TSS
50
yes
 
35GO:0051082 unfolded protein binding
106
at_TSS
50
yes
TF_ELK, MIT_001NRF1,
36GO:0008168 methyltransferase activity
98
at_TSS
48
yes
 
37GO:0016071 mRNA metabolism
202
at_TSS,before_TSS,after_TSS
47
yes
TF_ETS, MIT_011GABP,
38GO:0006397 mRNA processing
189
at_TSS,before_TSS
46
yes
MIT_011GABP,
39GO:0019941 modification-dependent protein catabolism
94
at_TSS
46
yes
MIT_020E4F1,
40GO:0006511 ubiquitin-dependent protein catabolism
94
at_TSS
46
yes
MIT_020E4F1,
41GO:0007399 nervous system development
301
before_TSS
46
yes
 
42GO:0016070 RNA metabolism
342
at_TSS,after_TSS
45
yes
TF_GABP, TF_SREBP1, TF_NFY,
43GO:0045182 translation regulator activity
90
at_TSS,after_TSS
44
yes
many
44GO:0008135 translation factor activity, nucleic acid binding
86
at_TSS,after_TSS
43
yes
many
45GO:0008026 ATP-dependent helicase activity
86
at_TSS
42
yes
TF_ELK, TF_E2F,
46GO:0007028 cytoplasm organization and biogenesis
82
at_TSS,after_TSS
40
yes
TF_ARNT, TF_ETS,
47GO:0030705 cytoskeleton-dependent intracellular transport
80
at_TSS
39
yes
 
48GO:0042254 ribosome biogenesis and assembly
74
at_TSS,after_TSS
37
yes
TF_AHR, TF_ARNT, TF_ETS,
49GO:0051243 negative regulation of cellular physiological process
330
before_TSS
37
 
TF_MAZR,
50GO:0008380 RNA splicing
154
before_TSS
37
yes
 
51GO:0000398 nuclear mRNA splicing, via spliceosome
149
before_TSS
36
yes
 
52GO:0006366 transcription from RNA polymerase II promoter
231
before_TSS,after_TSS
36
yes
TF_SP1, TF_AP2A,
53GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
149
before_TSS
36
yes
 
54GO:0000375 RNA splicing, via transesterification reactions
149
before_TSS
36
yes
 
55GO:0006913 nucleocytoplasmic transport
70
at_TSS
35
yes
 
56GO:0007046 ribosome biogenesis
67
at_TSS
33
yes
 
57GO:0030154 cell differentiation
538
at_TSS
29
 
TF_MAZR,
58GO:0003743 translation initiation factor activity
53
at_TSS,before_TSS
28
yes
TF_HTF, TF_ETS,
59GO:0045045 secretory pathway
101
at_TSS,after_TSS
28
yes
TF_GABP,
60GO:0048468 cell development
162
before_TSS
28
yes
 
61GO:0046903 secretion
123
at_TSS
25
 
TF_GABP, TF_ETS,
62GO:0043037 translation
128
before_TSS,after_TSS
24
 
TF_AHR, TF_ELK,
63GO:0016779 nucleotidyltransferase activity
91
at_TSS
23
 
TF_AHR,
64GO:0030182 neuron differentiation
137
before_TSS
23
yes
 
65GO:0007389 pattern specification
128
before_TSS
22
yes
 
66GO:0005975 carbohydrate metabolism
308
at_TSS
22
 
TF_SREBP1, MIT_015AP4,
67GO:0048519 negative regulation of biological process
408
at_TSS
22
 
MIT_024MAZ,
68GO:0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
34
after_TSS
21
yes
 
69GO:0000279 M phase
122
at_TSS
21
yes
TF_ATF1, MIT_001NRF1, MIT_022,
70GO:0048523 negative regulation of cellular process
375
at_TSS
21
 
MIT_024MAZ,
71GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
121
before_TSS
21
yes
TF_MAZR,
72GO:0004842 ubiquitin-protein ligase activity
263
after_TSS
21
 
TF_AP2, TF_AP2A,
73GO:0000278 mitotic cell cycle
135
at_TSS
21
yes
 
74GO:0003954 NADH dehydrogenase activity
32
after_TSS
20
yes
 
75GO:0015081 sodium ion transporter activity
32
after_TSS
20
yes
 
76GO:0016481 negative regulation of transcription
115
before_TSS
20
yes
 
77GO:0050136 NADH dehydrogenase (quinone) activity
32
after_TSS
20
yes
 
78GO:0008137 NADH dehydrogenase (ubiquinone) activity
32
after_TSS
20
yes
 
79GO:0009719 response to endogenous stimulus
159
at_TSS
19
 
TF_ELK,
80GO:0031324 negative regulation of cellular metabolism
132
before_TSS
19
 
TF_MAZR,
81GO:0042578 phosphoric ester hydrolase activity
222
before_TSS
19
 
TF_LYF,
82GO:0006357 regulation of transcription from RNA polymerase II promoter
191
after_TSS
19
 
TF_SP1, TF_AP2A,
83GO:0044262 cellular carbohydrate metabolism
205
at_TSS
18
 
TF_AP4, TF_HEN1, MIT_015AP4,
84GO:0006281 DNA repair
133
at_TSS
18
 
TF_ELK,
85GO:0006605 protein targeting
141
before_TSS
17
 
TF_POU6F,
86GO:0016791 phosphoric monoester hydrolase activity
171
before_TSS
17
 
TF_LYF,
87GO:0006457 protein folding
163
at_TSS
17
 
MIT_001NRF1,
88GO:0006403 RNA localization
22
at_TSS
16
yes
 
89GO:0050658 RNA transport
21
at_TSS
16
yes
 
90GO:0051168 nuclear export
26
at_TSS
16
yes
TF_ELK,
91GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
23
at_TSS
16
yes
 
92GO:0051236 establishment of RNA localization
21
at_TSS
16
yes
 
93GO:0050657 nucleic acid transport
21
at_TSS
16
yes
 
94GO:0016051 carbohydrate biosynthesis
57
at_TSS
15
 
TF_AP2, TF_AP2A,
95GO:0019207 kinase regulator activity
53
before_TSS
15
yes
 
96GO:0019887 protein kinase regulator activity
49
before_TSS
14
yes
 
97GO:0003735 structural constituent of ribosome
172
at_TSS
14
 
TF_GABP,
98GO:0007409 axonogenesis
81
at_TSS
13
 
TF_MAZR, MIT_006SP1,
99GO:0006066 alcohol metabolism
164
at_TSS
13
 
TF_NFY,

Pairs of TF_CREB binding sites with other TFBS

No.TFBS
Location
Total GO-s
Main GO annotation
N pairs for
main GO
Total genes
for main GO
1TF_ARNT
at_TSS,before_TSS,after_TSS
16
GO:0016043 cell organization and biogenesis
83
839
2TF_AHR
at_TSS,before_TSS,after_TSS
16
GO:0006996 organelle organization and biogenesis
104
645
3TF_ELK
at_TSS,after_TSS
15
GO:0008104 protein localization
94
508
4TF_E2F
at_TSS,before_TSS,after_TSS
14
GO:0016043 cell organization and biogenesis
52
839
5TF_HTF
at_TSS,before_TSS,after_TSS
14
GO:0016043 cell organization and biogenesis
75
839
6TF_SP1
at_TSS,before_TSS,after_TSS
14
GO:0006350 transcription
84
1461
7ADD_LRH
before_TSS,after_TSS
13
GO:0030554 adenyl nucleotide binding
89
1036
8TF_ATF6
before_TSS,after_TSS
12
GO:0016043 cell organization and biogenesis
71
839
9TF_GABP
at_TSS,after_TSS
12
GO:0008104 protein localization
72
508
10TF_ATF1
at_TSS,after_TSS
10
GO:0006259 DNA metabolism
41
427
11TF_MAZR
at_TSS,before_TSS,after_TSS
10
GO:0051243 negative regulation of cellular physiological process
37
330
12TF_PAX4
after_TSS
9
GO:0006259 DNA metabolism
27
427
13TF_PBX
at_TSS
9
GO:0006259 DNA metabolism
26
427
14MIT_041MEIS
before_TSS,after_TSS
9
GO:0003723 RNA binding
24
354
15TF_NF1
before_TSS,after_TSS
9
GO:0006259 DNA metabolism
24
427
16TF_COMP
at_TSS
9
GO:0006259 DNA metabolism
35
427
17TF_CREB
after_TSS
9
GO:0006259 DNA metabolism
33
427
18MIT_035MYOD
before_TSS,after_TSS
9
GO:0006259 DNA metabolism
26
427
19TF_EGR1
before_TSS
8
GO:0051276 chromosome organization and biogenesis
18
220
20TF_OLF1
after_TSS
8
GO:0051276 chromosome organization and biogenesis
14
220
21MIT_029
before_TSS
7
GO:0006996 organelle organization and biogenesis
49
645
22TF_AP2A
at_TSS,after_TSS
7
GO:0006512 ubiquitin cycle
53
390
23TF_ETS
at_TSS,after_TSS
7
GO:0003723 RNA binding
47
354
24TF_NFY
at_TSS
6
GO:0006333 chromatin assembly or disassembly
29
121
25TF_TAXCREB1
after_TSS
6
GO:0051276 chromosome organization and biogenesis
16
220
26TF_AP2
at_TSS,before_TSS,after_TSS
6
GO:0006512 ubiquitin cycle
53
390
27MIT_001NRF1
at_TSS
6
GO:0006996 organelle organization and biogenesis
37
645
28TF_POU6F
before_TSS
5
GO:0008104 protein localization
36
508
29MIT_019
after_TSS
5
GO:0006333 chromatin assembly or disassembly
13
121
30MIT_169
after_TSS
5
GO:0051276 chromosome organization and biogenesis
11
220
31MIT_003ELK
at_TSS
5
GO:0008104 protein localization
45
508
32MIT_045
before_TSS
4
GO:0006996 organelle organization and biogenesis
51
645
33MIT_005NFY
at_TSS
4
GO:0006333 chromatin assembly or disassembly
20
121
34TF_AP4
at_TSS,before_TSS
4
GO:0044262 cellular carbohydrate metabolism
12
205
35MIT_101
before_TSS
4
GO:0006333 chromatin assembly or disassembly
14
121
36MIT_022
at_TSS
3
GO:0000279 M phase
12
122
37MIT_024MAZ
at_TSS
3
GO:0003700 transcription factor activity
36
719
38MIT_020E4F1
at_TSS
3
GO:0006512 ubiquitin cycle
23
390
39MIT_006SP1
at_TSS,before_TSS
3
GO:0007049 cell cycle
51
443
40MIT_152
after_TSS
3
GO:0051276 chromosome organization and biogenesis
11
220
41MIT_011GABP
at_TSS
3
GO:0003723 RNA binding
23
354
42TF_SREBP1
at_TSS,after_TSS
2
GO:0016070 RNA metabolism
23
342
43TF_LYF
before_TSS
2
GO:0042578 phosphoric ester hydrolase activity
19
222
44MIT_031
at_TSS
2
GO:0019318 hexose metabolism
10
99
45MIT_015AP4
at_TSS
2
GO:0005975 carbohydrate metabolism
22
308
46MIT_017IRF
before_TSS
2
GO:0006323 DNA packaging
26
188
47MIT_060FOXO
before_TSS
2
GO:0051325 interphase
11
34
48TF_E47
before_TSS
2
GO:0006334 nucleosome assembly
11
86
49TF_RORA
after_TSS
2
GO:0015077 monovalent inorganic cation transporter activity
10
138
50TF_STAT
after_TSS
1
GO:0006461 protein complex assembly
11
123
51TF_RFX1
at_TSS
1
GO:0006399 tRNA metabolism
10
86
52MIT_092
after_TSS
1
GO:0006323 DNA packaging
10
188
53TF_CEBP
at_TSS
1
GO:0006461 protein complex assembly
10
123
54TF_RFX
before_TSS
1
GO:0007049 cell cycle
42
443
55MIT_058IPF1
before_TSS
1
GO:0006461 protein complex assembly
10
123
56TF_PAX2
after_TSS
1
GO:0015399 primary active transporter activity
11
168
57MIT_012MYOD
after_TSS
1
GO:0004540 ribonuclease activity
11
42
58TF_CART
before_TSS
1
GO:0006461 protein complex assembly
13
123
59TF_HEN1
at_TSS
1
GO:0044262 cellular carbohydrate metabolism
12
205

Details on Gene Ontology terms for targets of TF_CREB

Total number of genes = 12103
No.In pair
with
Multi-
ple
Conser-
ved
Location
Frequency
in list
U-clusters
in list
Genes with TFBS
in list, %
Genes with TFBS
total, %
Ratio
z
p
FDR
GO annotation
1none
 
yes
before_TSS
115
719
15.9
9.8
1.62
5.721
0
0
GO:0003700 transcription factor activity
2none
yes
 
before_TSS
81
354
22.8
14.7
1.54
4.352
0
0.0008
GO:0003723 RNA binding
3none
yes
yes
at_TSS
80
1541
5.1
2.7
1.88
6.237
0
0
GO:0019222 regulation of metabolism
4none
yes
yes
at_TSS
79
1510
5.2
2.7
1.89
6.268
0
0
GO:0031323 regulation of cellular metabolism
5none
yes
yes
at_TSS
77
1461
5.2
2.7
1.9
6.247
0
0
GO:0006350 transcription
6none
yes
yes
at_TSS
76
1410
5.3
2.7
1.95
6.414
0
0
GO:0045449 regulation of transcription
7none
yes
yes
at_TSS
76
1420
5.3
2.7
1.93
6.347
0
0
GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
8none
yes
yes
at_TSS
75
1383
5.4
2.7
1.96
6.424
0
0
GO:0006351 transcription, DNA-dependent
9none
yes
yes
at_TSS
74
1362
5.4
2.7
1.96
6.393
0
0
GO:0006355 regulation of transcription, DNA-dependent
10none
 
yes
after_TSS
69
302
22.8
15.1
1.5
3.761
0.0001
0.0017
GO:0005667
11none
yes
 
after_TSS
68
427
15.9
8.4
1.88
5.642
0
0
GO:0006259 DNA metabolism
12none
 
 
after_TSS
67
123
54.4
35.2
1.54
4.476
0
0.0001
GO:0006461 protein complex assembly
13none
 
 
after_TSS
65
121
53.7
35.2
1.52
4.265
0
0.0004
GO:0006333 chromatin assembly or disassembly
14none
 
 
after_TSS
60
95
63.1
35.2
1.79
5.708
0
0
GO:0031497 chromatin assembly
15none
 
 
after_TSS
55
86
63.9
35.2
1.81
5.584
0
0
GO:0006334 nucleosome assembly
16none
 
 
at_TSS
54
108
50
30.7
1.62
4.362
0
0.0015
GO:0004386 helicase activity
17none
yes
yes
at_TSS
53
941
5.6
2.7
2.04
5.601
0
0
GO:0030528 transcription regulator activity
18none
 
 
at_TSS
50
101
49.5
30.7
1.61
4.109
0
0.0145
GO:0016741 transferase activity, transferring one-carbon groups
19none
 
 
at_TSS
50
106
47.1
30.7
1.53
3.687
0.0002
0.0075
GO:0051082 unfolded protein binding
20none
 
 
after_TSS
50
78
64.1
35.2
1.81
5.344
0
0
GO:0000786
21none
 
 
after_TSS
50
88
56.8
35.2
1.61
4.243
0
0.0004
GO:0005694
22none
 
yes
before_TSS
48
302
15.8
9.8
1.61
3.582
0.0003
0.0019
GO:0005667
23none
 
 
at_TSS
48
98
48.9
30.7
1.59
3.934
0
0.0305
GO:0008168 methyltransferase activity
24none
yes
 
before_TSS
47
202
23.2
14.7
1.57
3.422
0.0006
0.0325
GO:0016071 mRNA metabolism
25none
yes
 
before_TSS
46
189
24.3
14.7
1.64
3.726
0.0001
0.0142
GO:0006397 mRNA processing
26none
 
 
at_TSS
46
94
48.9
30.7
1.59
3.843
0.0001
0.0111
GO:0006511 ubiquitin-dependent protein catabolism
27none
 
 
at_TSS
46
94
48.9
30.7
1.59
3.843
0.0001
0.0111
GO:0019941 modification-dependent protein catabolism
28none
 
yes
before_TSS
46
301
15.2
9.8
1.55
3.215
0.0013
0.0093
GO:0007399 nervous system development
29none
yes
 
after_TSS
45
342
13.1
8.4
1.55
3.166
0.0015
0.0235
GO:0016070 RNA metabolism
30none
 
 
at_TSS
44
90
48.8
30.7
1.59
3.75
0.0001
0.0034
GO:0045182 translation regulator activity
31none
 
 
at_TSS
43
86
50
30.7
1.62
3.889
0.0001
0.0021
GO:0008135 translation factor activity, nucleic acid binding
32none
yes
 
after_TSS
42
220
19
8.4
2.25
5.717
0
0
GO:0051276 chromosome organization and biogenesis
33none
 
 
at_TSS
42
86
48.8
30.7
1.58
3.654
0.0002
0.0157
GO:0008026 ATP-dependent helicase activity
34none
yes
yes
at_TSS
41
719
5.7
2.7
2.06
4.966
0
0
GO:0003700 transcription factor activity
35none
yes
 
after_TSS
41
208
19.7
8.4
2.32
5.881
0
0
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
36none
 
 
at_TSS
40
82
48.7
30.7
1.58
3.557
0.0003
0.0091
GO:0007028 cytoplasm organization and biogenesis
37none
 
 
at_TSS
39
80
48.7
30.7
1.58
3.507
0.0004
0.0829
GO:0030705 cytoskeleton-dependent intracellular transport
38none
yes
 
after_TSS
38
179
21.2
8.4
2.5
6.184
0
0
GO:0006325 establishment and/or maintenance of chromatin architecture
39none
yes
 
after_TSS
38
188
20.2
8.4
2.38
5.835
0
0
GO:0006323 DNA packaging
40none
 
 
at_TSS
37
74
50
30.7
1.62
3.606
0.0003
0.0087
GO:0042254 ribosome biogenesis and assembly
41none
yes
 
before_TSS
37
154
24
14.7
1.62
3.249
0.0011
0.047
GO:0008380 RNA splicing
42none
yes
 
before_TSS
36
149
24.1
14.7
1.63
3.242
0.0011
0.0482
GO:0000398 nuclear mRNA splicing, via spliceosome
43none
yes
 
before_TSS
36
149
24.1
14.7
1.63
3.242
0.0011
0.0482
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
44none
 
yes
before_TSS
36
231
15.5
9.8
1.58
2.964
0.003
0.0529
GO:0006366 transcription from RNA polymerase II promoter
45none
yes
 
before_TSS
36
149
24.1
14.7
1.63
3.242
0.0011
0.0482
GO:0000375 RNA splicing, via transesterification reactions
46none
yes
 
before_TSS
35
121
28.9
14.7
1.95
4.402
0
0.0005
GO:0006333 chromatin assembly or disassembly
47none
 
 
at_TSS
35
70
50
30.7
1.62
3.506
0.0004
0.0832
GO:0006913 nucleocytoplasmic transport
48none
yes
 
after_TSS
33
121
27.2
8.4
3.22
7.472
0
0
GO:0006333 chromatin assembly or disassembly
49none
 
 
at_TSS
33
67
49.2
30.7
1.6
3.297
0.0009
0.0238
GO:0007046 ribosome biogenesis
50none
yes
 
after_TSS
33
123
26.8
8.4
3.17
7.357
0
0
GO:0006461 protein complex assembly
51none
 
 
after_TSS
31
53
58.4
35.2
1.65
3.543
0.0003
0.0206
GO:0019866
52none
yes
 
after_TSS
30
95
31.5
8.4
3.73
8.128
0
0
GO:0031497 chromatin assembly
53none
yes
 
after_TSS
29
78
37.1
8.4
4.39
9.143
0
0
GO:0000786
54none
yes
 
after_TSS
29
86
33.7
8.4
3.98
8.447
0
0
GO:0006334 nucleosome assembly
55none
 
yes
after_TSS
28
101
27.7
15.1
1.82
3.528
0.0004
0.0766
GO:0045045 secretory pathway
56none
 
 
at_TSS
28
53
52.8
30.7
1.71
3.496
0.0004
0.0144
GO:0003743 translation initiation factor activity
57none
 
yes
before_TSS
28
162
17.2
9.8
1.75
3.206
0.0013
0.0234
GO:0048468 cell development
58none
yes
 
after_TSS
27
88
30.6
8.4
3.62
7.517
0
0
GO:0005694
59none
yes
 
before_TSS
26
88
29.5
14.7
1.99
3.913
0
0.0047
GO:0005694
60none
yes
yes
before_TSS
23
443
5.1
1.7
2.93
5.57
0
0
GO:0007049 cell cycle
61none
 
yes
before_TSS
23
137
16.7
9.8
1.7
2.749
0.0059
0.0546
GO:0030182 neuron differentiation
62none
 
yes
before_TSS
22
128
17.1
9.8
1.74
2.809
0.0049
0.0298
GO:0007389 pattern specification
63none
yes
 
at_TSS
21
122
17.2
8.1
2.1
3.669
0.0002
0.0068
GO:0000279 M phase
64none
yes
 
at_TSS
21
135
15.5
8.1
1.9
3.154
0.0016
0.0842
GO:0000278 mitotic cell cycle
65none
 
yes
before_TSS
21
121
17.3
9.8
1.76
2.793
0.0052
0.0682
GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
66none
 
 
after_TSS
21
34
61.7
35.2
1.75
3.236
0.0012
0.0739
GO:0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
67none
 
 
after_TSS
20
32
62.5
35.2
1.77
3.226
0.0012
0.0656
GO:0008137 NADH dehydrogenase (ubiquinone) activity
68none
 
 
after_TSS
20
32
62.5
35.2
1.77
3.226
0.0012
0.0656
GO:0015081 sodium ion transporter activity
69none
 
 
after_TSS
20
32
62.5
35.2
1.77
3.226
0.0012
0.0656
GO:0003954 NADH dehydrogenase activity
70none
 
yes
before_TSS
20
115
17.3
9.8
1.76
2.735
0.0062
0.0787
GO:0016481 negative regulation of transcription
71none
yes
 
at_TSS
20
86
23.2
8.1
2.84
5.129
0
0
GO:0008135 translation factor activity, nucleic acid binding
72none
yes
 
at_TSS
20
90
22.2
8.1
2.72
4.889
0
0
GO:0045182 translation regulator activity
73none
 
 
after_TSS
20
32
62.5
35.2
1.77
3.226
0.0012
0.0656
GO:0050136 NADH dehydrogenase (quinone) activity
74none
yes
 
at_TSS
19
94
20.2
8.1
2.47
4.283
0
0.0022
GO:0006511 ubiquitin-dependent protein catabolism
75none
yes
yes
at_TSS
19
302
6.2
2.7
2.27
3.794
0.0001
0.0019
GO:0005667
76none
yes
 
at_TSS
19
94
20.2
8.1
2.47
4.283
0
0.0022
GO:0019941 modification-dependent protein catabolism
77none
 
 
at_TSS
17
28
60.7
30.7
1.97
3.444
0.0005
0.0419
GO:0000139
78none
yes
yes
before_TSS
17
302
5.6
1.7
3.18
5.155
0
0
GO:0005667
79none
 
 
at_TSS
16
21
76.1
30.7
2.48
4.52
0
0.0011
GO:0050657 nucleic acid transport
80none
 
 
at_TSS
16
23
69.5
30.7
2.26
4.041
0
0.0097
GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
81none
 
 
at_TSS
16
21
76.1
30.7
2.48
4.52
0
0.0011
GO:0051236 establishment of RNA localization
82none
 
 
at_TSS
16
26
61.5
30.7
2
3.409
0.0006
0.034
GO:0051168 nuclear export
83none
 
 
at_TSS
16
22
72.7
30.7
2.36
4.274
0
0.0035
GO:0006403 RNA localization
84none
 
 
at_TSS
16
21
76.1
30.7
2.48
4.52
0
0.0011
GO:0050658 RNA transport
85none
 
yes
before_TSS
16
51
31.3
9.8
3.19
5.177
0
0
GO:0000785
86none
 
 
at_TSS
15
23
65.2
30.7
2.12
3.589
0.0003
0.0242
GO:0005830
87none
 
yes
before_TSS
15
53
28.3
9.8
2.87
4.525
0
0.0011
GO:0019207 kinase regulator activity
88none
 
yes
before_TSS
14
49
28.5
9.8
2.9
4.414
0
0.0018
GO:0019887 protein kinase regulator activity
89none
yes
 
at_TSS
14
78
17.9
8.1
2.19
3.166
0.0015
0.0628
GO:0005764
90none
yes
 
at_TSS
11
54
20.3
8.1
2.49
3.283
0.001
0.0469
GO:0005681
91none
yes
 
at_TSS
10
39
25.6
8.1
3.14
3.992
0
0.0079
GO:0051321 meiotic cell cycle
92none
yes
 
at_TSS
10
39
25.6
8.1
3.14
3.992
0
0.0079
GO:0007126 meiosis
93none
yes
 
at_TSS
10
39
25.6
8.1
3.14
3.992
0
0.0079
GO:0051327 M phase of meiotic cell cycle
94ADD_LRH
 
 
before_TSS
89
1036
8.5
5.6
1.52
4.344
0
0.0671
GO:0030554 adenyl nucleotide binding
95ADD_LRH
 
 
before_TSS
87
1011
8.6
5.6
1.53
4.307
0
0.0794
GO:0005524 ATP binding
96ADD_LRH
 
 
after_TSS
60
839
7.1
3.9
1.79
4.865
0
0.0044
GO:0016043 cell organization and biogenesis
97ADD_LRH
 
 
after_TSS
47
645
7.2
3.9
1.82
4.41
0
0.0148
GO:0006996 organelle organization and biogenesis
98ADD_LRH
 
 
after_TSS
35
427
8.1
3.9
2.05
4.533
0
0.0049
GO:0006259 DNA metabolism
99ADD_LRH
 
 
after_TSS
25
220
11.3
3.9
2.85
5.65
0
0
GO:0051276 chromosome organization and biogenesis
100ADD_LRH
 
 
after_TSS
24
208
11.5
3.9
2.89
5.621
0
0
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
101ADD_LRH
 
 
after_TSS
24
188
12.7
3.9
3.2
6.206
0
0
GO:0006323 DNA packaging
102ADD_LRH
 
 
after_TSS
22
123
17.8
3.9
4.49
7.925
0
0
GO:0006461 protein complex assembly
103ADD_LRH
 
 
after_TSS
22
179
12.2
3.9
3.08
5.726
0
0
GO:0006325 establishment and/or maintenance of chromatin architecture
104ADD_LRH
 
 
after_TSS
21
121
17.3
3.9
4.35
7.56
0
0
GO:0006333 chromatin assembly or disassembly
105ADD_LRH
 
 
after_TSS
20
95
21
3.9
5.28
8.541
0
0
GO:0031497 chromatin assembly
106ADD_LRH
 
 
after_TSS
20
86
23.2
3.9
5.83
9.172
0
0
GO:0006334 nucleosome assembly
107ADD_LRH
 
 
after_TSS
19
78
24.3
3.9
6.11
9.232
0
0
GO:0000786
108ADD_LRH
 
 
before_TSS
18
123
14.6
5.6
2.6
4.364
0
0.0055
GO:0006461 protein complex assembly
109ADD_LRH
 
 
before_TSS
16
95
16.8
5.6
2.99
4.769
0
0.0008
GO:0031497 chromatin assembly
110ADD_LRH
 
 
before_TSS
15
86
17.4
5.6
3.1
4.778
0
0.0006
GO:0006334 nucleosome assembly
111ADD_LRH
 
 
before_TSS
15
78
19.2
5.6
3.42
5.237
0
0
GO:0000786
112ADD_LRH
 
 
after_TSS
15
88
17
3.9
4.28
6.289
0
0
GO:0005694
113ADD_LRH
 
 
after_TSS
11
53
20.7
3.9
5.21
6.257
0
0
GO:0019866
114ADD_LRH
 
yes
before_TSS
10
188
5.3
0.4
11.7
9.994
0
0
GO:0006323 DNA packaging
115ADD_LRH
 
yes
before_TSS
10
179
5.5
0.4
12.29
10.284
0
0
GO:0006325 establishment and/or maintenance of chromatin architecture
116MIT_001NRF1
 
 
at_TSS
37
645
5.7
3.1
1.84
3.938
0
0.0582
GO:0006996 organelle organization and biogenesis
117MIT_001NRF1
 
 
at_TSS
17
163
10.4
3.1
3.34
5.411
0
0.0002
GO:0006457 protein folding
118MIT_001NRF1
 
 
at_TSS
13
106
12.2
3.1
3.93
5.445
0
0.0002
GO:0051082 unfolded protein binding
119MIT_001NRF1
 
 
at_TSS
12
86
13.9
3.1
4.47
5.806
0
0
GO:0008135 translation factor activity, nucleic acid binding
120MIT_001NRF1
 
 
at_TSS
12
90
13.3
3.1
4.28
5.6
0
0.0001
GO:0045182 translation regulator activity
121MIT_001NRF1
 
 
at_TSS
12
122
9.8
3.1
3.15
4.294
0
0.0361
GO:0000279 M phase
122MIT_003ELK
 
 
at_TSS
45
508
8.8
4.2
2.08
5.279
0
0.0004
GO:0008104 protein localization
123MIT_003ELK
 
 
at_TSS
43
492
8.7
4.2
2.06
5.059
0
0.0009
GO:0045184 establishment of protein localization
124MIT_003ELK
 
 
at_TSS
43
476
9
4.2
2.13
5.297
0
0.0002
GO:0015031 protein transport
125MIT_003ELK
 
 
at_TSS
40
354
11.2
4.2
2.66
6.692
0
0
GO:0003723 RNA binding
126MIT_003ELK
 
 
at_TSS
32
350
9.1
4.2
2.15
4.621
0
0.0068
GO:0006886 intracellular protein transport
127MIT_003ELK
 
 
at_TSS
10
54
18.5
4.2
4.36
5.219
0
0.0011
GO:0005681
128MIT_005NFY
 
 
at_TSS
20
121
16.5
3.6
4.55
7.628
0
0
GO:0006333 chromatin assembly or disassembly
129MIT_005NFY
 
 
at_TSS
19
123
15.4
3.6
4.25
7.047
0
0
GO:0006461 protein complex assembly
130MIT_005NFY
yes
 
at_TSS
10
179
5.5
1
5.54
6.177
0
0
GO:0006325 establishment and/or maintenance of chromatin architecture
131MIT_005NFY
yes
 
at_TSS
10
188
5.3
1
5.27
5.963
0
0
GO:0006323 DNA packaging
132MIT_005NFY
yes
 
at_TSS
10
121
8.2
1
8.19
8.03
0
0
GO:0006333 chromatin assembly or disassembly
133MIT_006SP1
 
 
before_TSS
51
443
11.5
6.1
1.86
4.758
0
0.0049
GO:0007049 cell cycle
134MIT_006SP1
 
yes
at_TSS
13
81
16
5
3.18
4.551
0
0.0461
GO:0007409 axonogenesis
135MIT_006SP1
 
yes
at_TSS
10
51
19.6
5
3.89
4.771
0
0.0792
GO:0003682 chromatin binding
136MIT_011GABP
 
 
at_TSS
23
354
6.4
2.1
3.01
5.706
0
0
GO:0003723 RNA binding
137MIT_011GABP
 
 
at_TSS
15
202
7.4
2.1
3.44
5.199
0
0.0012
GO:0016071 mRNA metabolism
138MIT_011GABP
 
 
at_TSS
13
189
6.8
2.1
3.18
4.504
0
0.036
GO:0006397 mRNA processing
139MIT_012MYOD
 
 
before_TSS
15
88
17
6.8
2.49
3.815
0.0001
0.049
GO:0005694
140MIT_012MYOD
 
 
after_TSS
11
42
26.1
5.8
4.45
5.602
0
0.0009
GO:0004540 ribonuclease activity
141MIT_015AP4
 
 
at_TSS
22
308
7.1
2.8
2.54
4.662
0
0.0451
GO:0005975 carbohydrate metabolism
142MIT_015AP4
 
 
at_TSS
18
205
8.7
2.8
3.12
5.218
0
0.0078
GO:0044262 cellular carbohydrate metabolism
143MIT_015AP4
 
 
before_TSS
11
88
12.5
4.3
2.88
3.779
0.0001
0.0557
GO:0005694
144MIT_015AP4
 
 
after_TSS
10
45
22.2
3.8
5.77
6.416
0
0
GO:0005923
145MIT_017IRF
 
 
before_TSS
26
188
13.8
6
2.3
4.549
0
0.003
GO:0006323 DNA packaging
146MIT_017IRF
 
 
before_TSS
23
179
12.8
6
2.13
3.881
0.0001
0.0449
GO:0006325 establishment and/or maintenance of chromatin architecture
147MIT_019
 
 
after_TSS
13
121
10.7
3.5
3.01
4.284
0
0.0103
GO:0006333 chromatin assembly or disassembly
148MIT_019
 
 
after_TSS
12
88
13.6
3.5
3.82
5.118
0
0.0001
GO:0005694
149MIT_019
 
yes
after_TSS
11
220
5
1.1
4.48
5.536
0
0
GO:0051276 chromosome organization and biogenesis
150MIT_019
 
yes
after_TSS
11
208
5.2
1.1
4.74
5.78
0
0
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
151MIT_019
 
yes
after_TSS
10
179
5.5
1.1
5
5.738
0
0
GO:0006325 establishment and/or maintenance of chromatin architecture
152MIT_019
 
yes
after_TSS
10
188
5.3
1.1
4.76
5.531
0
0
GO:0006323 DNA packaging
153MIT_020E4F1
 
 
at_TSS
23
390
5.8
2.6
2.25
4.12
0
0.0629
GO:0006512 ubiquitin cycle
154MIT_020E4F1
 
 
at_TSS
11
94
11.7
2.6
4.46
5.535
0
0.0013
GO:0019941 modification-dependent protein catabolism
155MIT_020E4F1
 
 
at_TSS
11
94
11.7
2.6
4.46
5.535
0
0.0013
GO:0006511 ubiquitin-dependent protein catabolism
156MIT_022
 
 
at_TSS
12
122
9.8
2.6
3.75
5.016
0
0.0014
GO:0000279 M phase
157MIT_022
 
 
at_TSS
10
90
11.1
2.6
4.24
5.063
0
0.0009
GO:0045182 translation regulator activity
158MIT_022
 
 
at_TSS
10
86
11.6
2.6
4.43
5.249
0
0.0004
GO:0008135 translation factor activity, nucleic acid binding
159MIT_024MAZ
 
yes
at_TSS
36
719
5
2.2
2.19
5.049
0
0.0007
GO:0003700 transcription factor activity
160MIT_024MAZ
yes
 
at_TSS
22
408
5.3
2
2.68
4.957
0
0.0309
GO:0048519 negative regulation of biological process
161MIT_024MAZ
yes
 
at_TSS
21
375
5.6
2
2.78
5.037
0
0.0204
GO:0048523 negative regulation of cellular process
162MIT_029
 
 
before_TSS
49
645
7.5
4.3
1.73
4.09
0
0.0503
GO:0006996 organelle organization and biogenesis
163MIT_029
 
 
before_TSS
19
188
10.1
4.3
2.3
3.858
0.0001
0.0461
GO:0006323 DNA packaging
164MIT_029
 
 
before_TSS
19
179
10.6
4.3
2.41
4.098
0
0.02
GO:0006325 establishment and/or maintenance of chromatin architecture
165MIT_029
 
 
before_TSS
15
121
12.3
4.3
2.82
4.323
0
0.0059
GO:0006333 chromatin assembly or disassembly
166MIT_029
 
 
before_TSS
15
123
12.1
4.3
2.77
4.249
0
0.0092
GO:0006461 protein complex assembly
167MIT_029
 
 
before_TSS
13
86
15.1
4.3
3.44
4.875
0
0.0004
GO:0006334 nucleosome assembly
168MIT_029
 
 
before_TSS
13
95
13.6
4.3
3.11
4.441
0
0.0033
GO:0031497 chromatin assembly
169MIT_029
 
 
before_TSS
10
78
12.8
4.3
2.92
3.648
0.0002
0.0892
GO:0000786
170MIT_031
 
 
at_TSS
10
101
9.9
2.5
3.81
4.638
0
0.076
GO:0005996 monosaccharide metabolism
171MIT_031
 
 
at_TSS
10
99
10.1
2.5
3.89
4.717
0
0.0517
GO:0019318 hexose metabolism
172MIT_035MYOD
 
 
after_TSS
26
427
6
2.6
2.31
4.535
0
0.0049
GO:0006259 DNA metabolism
173MIT_035MYOD
 
 
after_TSS
15
179
8.3
2.6
3.17
4.833
0
0.001
GO:0006325 establishment and/or maintenance of chromatin architecture
174MIT_035MYOD
 
 
after_TSS
15
220
6.8
2.6
2.58
3.908
0
0.0558
GO:0051276 chromosome organization and biogenesis
175MIT_035MYOD
 
 
after_TSS
15
188
7.9
2.6
3.02
4.608
0
0.003
GO:0006323 DNA packaging
176MIT_035MYOD
 
 
after_TSS
15
208
7.2
2.6
2.73
4.155
0
0.0219
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
177MIT_035MYOD
 
 
before_TSS
13
179
7.2
2.7
2.62
3.692
0.0002
0.0882
GO:0006325 establishment and/or maintenance of chromatin architecture
178MIT_035MYOD
 
 
after_TSS
12
121
9.9
2.6
3.76
5.025
0
0.0003
GO:0006333 chromatin assembly or disassembly
179MIT_035MYOD
 
 
after_TSS
11
86
12.7
2.6
4.85
5.899
0
0
GO:0006334 nucleosome assembly
180MIT_035MYOD
 
 
before_TSS
10
95
10.5
2.7
3.8
4.627
0
0.0014
GO:0031497 chromatin assembly
181MIT_035MYOD
 
 
before_TSS
10
88
11.3
2.7
4.1
4.932
0
0.0003
GO:0005694
182MIT_035MYOD
 
 
before_TSS
10
86
11.6
2.7
4.2
5.026
0
0.0002
GO:0006334 nucleosome assembly
183MIT_035MYOD
 
 
before_TSS
10
78
12.8
2.7
4.63
5.429
0
0
GO:0000786
184MIT_035MYOD
 
 
before_TSS
10
123
8.1
2.7
2.93
3.643
0.0002
0.0924
GO:0006461 protein complex assembly
185MIT_041MEIS
 
 
before_TSS
24
354
6.7
2.9
2.29
4.307
0
0.055
GO:0003723 RNA binding
186MIT_041MEIS
 
 
after_TSS
12
179
6.7
1.9
3.49
4.705
0
0.0017
GO:0006325 establishment and/or maintenance of chromatin architecture
187MIT_041MEIS
 
 
after_TSS
12
220
5.4
1.9
2.84
3.861
0.0001
0.065
GO:0051276 chromosome organization and biogenesis
188MIT_041MEIS
 
 
after_TSS
12
208
5.7
1.9
3
4.087
0
0.0281
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
189MIT_041MEIS
 
 
after_TSS
12
188
6.3
1.9
3.32
4.5
0
0.0048
GO:0006323 DNA packaging
190MIT_041MEIS
 
 
after_TSS
11
95
11.5
1.9
6.04
6.894
0
0
GO:0031497 chromatin assembly
191MIT_041MEIS
 
 
after_TSS
11
121
9
1.9
4.74
5.783
0
0
GO:0006333 chromatin assembly or disassembly
192MIT_041MEIS
 
 
after_TSS
10
123
8.1
1.9
4.24
5.05
0
0.0002
GO:0006461 protein complex assembly
193MIT_041MEIS
 
 
after_TSS
10
86
11.6
1.9
6.06
6.59
0
0
GO:0006334 nucleosome assembly
194MIT_045
 
 
before_TSS
51
645
7.9
4.5
1.73
4.186
0
0.0395
GO:0006996 organelle organization and biogenesis
195MIT_045
 
 
before_TSS
17
121
14
4.5
3.08
5.027
0
0.0002
GO:0006333 chromatin assembly or disassembly
196MIT_045
 
 
before_TSS
12
95
12.6
4.5
2.76
3.785
0.0001
0.0492
GO:0031497 chromatin assembly
197MIT_045
 
 
before_TSS
11
86
12.7
4.5
2.8
3.671
0.0002
0.0756
GO:0006334 nucleosome assembly
198MIT_045
 
 
before_TSS
11
78
14.1
4.5
3.09
4.052
0
0.0184
GO:0000786
199MIT_058IPF1
 
 
before_TSS
10
123
8.1
2.1
3.81
4.629
0
0.0018
GO:0006461 protein complex assembly
200MIT_060FOXO
 
 
before_TSS
11
34
32.3
9
3.57
4.747
0
0.0892
GO:0051329 interphase of mitotic cell cycle
201MIT_060FOXO
 
 
before_TSS
11
34
32.3
9
3.57
4.747
0
0.0892
GO:0051325 interphase
202MIT_092
 
 
after_TSS
10
188
5.3
1.5
3.4
4.187
0
0.0187
GO:0006323 DNA packaging
203MIT_101
 
 
before_TSS
14
121
11.5
3.6
3.17
4.676
0
0.0012
GO:0006333 chromatin assembly or disassembly
204MIT_101
 
 
before_TSS
14
88
15.9
3.6
4.36
6.162
0
0
GO:0005694
205MIT_101
 
 
before_TSS
13
123
10.5
3.6
2.9
4.119
0
0.0161
GO:0006461 protein complex assembly
206MIT_101
 
 
before_TSS
12
78
15.3
3.6
4.22
5.551
0
0
GO:0000786
207MIT_101
 
 
before_TSS
12
95
12.6
3.6
3.46
4.693
0
0.001