Gene Ontology terms for targets of TF

CisView Mouse (mm6, March 2005)

Main Gene Ontology terms for targets of TF_E2F

No.	GO annotation	Total genes with GO	Location	Max no. of genes with TF_E2F	TF_E2F alone	In pair with
1	GO:0003676 nucleic acid binding	2302	after_TSS	146	yes
2	GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolism	2284	before_TSS,after_TSS	142	yes
3	GO:0006259 DNA metabolism	427	at_TSS,before_TSS,after_TSS	118	yes	many
4	GO:0007049 cell cycle	443	at_TSS,after_TSS	117	yes	TF_SP1, MIT_006SP1,
5	GO:0003677 DNA binding	1509	after_TSS	103	yes
6	GO:0030528 transcription regulator activity	941	at_TSS,before_TSS,after_TSS	96	yes	TF_AHR,
7	GO:0003723 RNA binding	354	at_TSS,after_TSS	87	yes	TF_CREB, TF_GABP,
8	GO:0006350 transcription	1461	at_TSS,before_TSS	84		TF_AP2, TF_MAZR,
9	GO:0048513 organ development	852	at_TSS,before_TSS	82	yes
10	GO:0009653 morphogenesis	811	at_TSS,after_TSS	81	yes
11	GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism	1420	at_TSS	80		TF_AP2,
12	GO:0030554 adenyl nucleotide binding	1036	at_TSS	80		TF_ELK,
13	GO:0051276 chromosome organization and biogenesis	220	at_TSS,before_TSS,after_TSS	80	yes	many
14	GO:0005524 ATP binding	1011	at_TSS	79		TF_ELK,
15	GO:0045449 regulation of transcription	1410	at_TSS	79		TF_AP2,
16	GO:0009887 organ morphogenesis	674	at_TSS,after_TSS	74	yes	TF_MAZR,
17	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)	208	at_TSS,before_TSS,after_TSS	74	yes	many
18	GO:0003700 transcription factor activity	719	at_TSS,before_TSS,after_TSS	71	yes	TF_AHR,
19	GO:0006323 DNA packaging	188	at_TSS,before_TSS,after_TSS	67	yes	many
20	GO:0016887 ATPase activity	280	at_TSS	67	yes	TF_GABP, TF_ELK, TF_ETS,
21	GO:0006325 establishment and/or maintenance of chromatin architecture	179	at_TSS,before_TSS,after_TSS	64	yes	many
22	GO:0000074 regulation of progression through cell cycle	246	at_TSS	64	yes	MIT_024MAZ, TF_SP1, MIT_006SP1,
23	GO:0042623 ATPase activity, coupled	256	at_TSS	62	yes	TF_GABP, TF_ELK,
24	GO:0016043 cell organization and biogenesis	839	before_TSS,after_TSS	55	yes	TF_CREB, TF_ATF1,
25	GO:0030154 cell differentiation	538	at_TSS	54	yes
26	GO:0009790 embryonic development	170	before_TSS	54	yes
27	GO:0009058 biosynthesis	878	after_TSS	53		TF_ATF6,
28	GO:0006461 protein complex assembly	123	before_TSS,after_TSS	52	yes	many
29	GO:0006333 chromatin assembly or disassembly	121	at_TSS,before_TSS,after_TSS	48	yes	many
30	GO:0006996 organelle organization and biogenesis	645	before_TSS,after_TSS	48	yes	TF_ATF1, TF_CREB,
31	GO:0044249 cellular biosynthesis	776	after_TSS	48		TF_ATF6,
32	GO:0009719 response to endogenous stimulus	159	at_TSS,after_TSS	47	yes
33	GO:0007167 enzyme linked receptor protein signaling pathway	157	before_TSS	47	yes
34	GO:0006974 response to DNA damage stimulus	156	at_TSS,after_TSS	45	yes
35	GO:0007399 nervous system development	301	at_TSS,after_TSS	45	yes
36	GO:0016817 hydrolase activity, acting on acid anhydrides	450	at_TSS	44		TF_GABP, TF_ELK,
37	GO:0016462 pyrophosphatase activity	447	at_TSS	44		TF_GABP, TF_ELK,
38	GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	450	at_TSS	44		TF_GABP, TF_ELK,
39	GO:0017111 nucleoside-triphosphatase activity	429	at_TSS	43		TF_GABP, TF_ELK,
40	GO:0031497 chromatin assembly	95	at_TSS,before_TSS,after_TSS	41	yes	many
41	GO:0031324 negative regulation of cellular metabolism	132	before_TSS	41	yes
42	GO:0000278 mitotic cell cycle	135	at_TSS	41	yes	TF_ARNT,
43	GO:0006334 nucleosome assembly	86	at_TSS,before_TSS,after_TSS	40	yes	many
44	GO:0006281 DNA repair	133	at_TSS,after_TSS	39	yes
45	GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism	121	before_TSS	39	yes
46	GO:0006457 protein folding	163	at_TSS	39	yes	TF_ETS, MIT_020E4F1,
47	GO:0000279 M phase	122	at_TSS	38	yes	TF_HTF, TF_ATF6, TF_ARNT,
48	GO:0016481 negative regulation of transcription	115	before_TSS	37	yes
49	GO:0009165 nucleotide biosynthesis	132	at_TSS	36	yes
50	GO:0006260 DNA replication	90	at_TSS,after_TSS	35	yes	TF_COMP, TF_GABP, TF_NFY,
51	GO:0051301 cell division	134	at_TSS,after_TSS	34	yes	TF_SP1, TF_ARNT,
52	GO:0004386 helicase activity	108	at_TSS	34	yes	many
53	GO:0000910 cytokinesis	125	at_TSS,before_TSS,after_TSS	33	yes	many
54	GO:0048519 negative regulation of biological process	408	before_TSS	32	yes
55	GO:0043118 negative regulation of physiological process	342	before_TSS	30	yes
56	GO:0045892 negative regulation of transcription, DNA-dependent	82	before_TSS	29	yes
57	GO:0008283 cell proliferation	226	at_TSS	29	yes
58	GO:0051243 negative regulation of cellular physiological process	330	before_TSS	29	yes
59	GO:0008026 ATP-dependent helicase activity	86	at_TSS	29	yes	many
60	GO:0048523 negative regulation of cellular process	375	before_TSS	26	yes
61	GO:0007417 central nervous system development	76	at_TSS,before_TSS,after_TSS	26	yes	TF_MAZR,
62	GO:0016070 RNA metabolism	342	before_TSS	26	yes
63	GO:0007389 pattern specification	128	before_TSS,after_TSS	25	yes
64	GO:0000087 M phase of mitotic cell cycle	89	at_TSS	25	yes	TF_ELK,
65	GO:0007420 brain development	63	before_TSS,after_TSS	24	yes	TF_MAZR,
66	GO:0007067 mitosis	88	at_TSS	24	yes	TF_ELK,
67	GO:0000122 negative regulation of transcription from RNA polymerase II promoter	62	before_TSS	23	yes
68	GO:0007610 behavior	229	before_TSS	22	yes
69	GO:0006366 transcription from RNA polymerase II promoter	231	before_TSS,after_TSS	21	yes	MIT_006SP1,
70	GO:0006396 RNA processing	273	before_TSS,after_TSS	21	yes
71	GO:0016071 mRNA metabolism	202	before_TSS	20	yes
72	GO:0006357 regulation of transcription from RNA polymerase II promoter	191	before_TSS	20	yes	TF_SP1, MIT_006SP1,
73	GO:0007626 locomotory behavior	187	before_TSS	19	yes
74	GO:0009892 negative regulation of metabolism	149	before_TSS	19	yes
75	GO:0016564 transcriptional repressor activity	64	after_TSS	18	yes
76	GO:0030182 neuron differentiation	137	before_TSS,after_TSS	18	yes	TF_SP1,
77	GO:0006397 mRNA processing	189	before_TSS	17	yes
78	GO:0006261 DNA-dependent DNA replication	32	at_TSS	17	yes	TF_NFY,
79	GO:0006928 cell motility	162	before_TSS	16	yes
80	GO:0040011 locomotion	165	before_TSS	16	yes
81	GO:0007409 axonogenesis	81	before_TSS,after_TSS	16	yes
82	GO:0000398 nuclear mRNA splicing, via spliceosome	149	before_TSS	15	yes	TF_NFY,
83	GO:0051327 M phase of meiotic cell cycle	39	at_TSS	15	yes
84	GO:0016477 cell migration	141	before_TSS	15	yes
85	GO:0008380 RNA splicing	154	before_TSS	15	yes
86	GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	149	before_TSS	15	yes	TF_NFY,
87	GO:0051321 meiotic cell cycle	39	at_TSS	15	yes
88	GO:0000375 RNA splicing, via transesterification reactions	149	before_TSS	15	yes	TF_NFY,
89	GO:0007126 meiosis	39	at_TSS	15	yes
90	GO:0007398 ectoderm development	29	before_TSS	14	yes
91	GO:0030900 forebrain development	31	before_TSS	14	yes
92	GO:0051082 unfolded protein binding	106	at_TSS	13		TF_ETS,
93	GO:0048666 neuron development	108	before_TSS	13	yes
94	GO:0031175 neurite morphogenesis	96	before_TSS	12	yes
95	GO:0048667 neuron morphogensis during differentiation	96	before_TSS	12	yes
96	GO:0000904 cellular morphogenesis during differentiation	107	before_TSS	12	yes
97	GO:0008094 DNA-dependent ATPase activity	24	at_TSS	12	yes
98	GO:0009880 embryonic pattern specification	20	before_TSS	11	yes
99	GO:0019207 kinase regulator activity	53	at_TSS	11	yes	TF_MAZR,

Pairs of TF_E2F binding sites with other TFBS

No.	TFBS	Location	Total GO-s	Main GO annotation	N pairs for main GO	Total genes for main GO
1	TF_CREB	at_TSS,before_TSS,after_TSS	14	GO:0016043 cell organization and biogenesis	52	839
2	TF_ATF1	at_TSS,before_TSS,after_TSS	13	GO:0016043 cell organization and biogenesis	55	839
3	TF_ELK	at_TSS	13	GO:0030554 adenyl nucleotide binding	80	1036
4	TF_AHR	before_TSS,after_TSS	11	GO:0030528 transcription regulator activity	74	941
5	TF_GABP	at_TSS,after_TSS	10	GO:0016462 pyrophosphatase activity	33	447
6	TF_E2F	after_TSS	9	GO:0006259 DNA metabolism	24	427
7	ADD_LRH	before_TSS,after_TSS	8	GO:0051276 chromosome organization and biogenesis	18	220
8	TF_RFX1	before_TSS	8	GO:0051276 chromosome organization and biogenesis	16	220
9	MIT_092	after_TSS	8	GO:0051276 chromosome organization and biogenesis	11	220
10	MIT_045	after_TSS	8	GO:0006323 DNA packaging	15	188
11	MIT_140	before_TSS	8	GO:0051276 chromosome organization and biogenesis	14	220
12	MIT_101	before_TSS	8	GO:0051276 chromosome organization and biogenesis	15	220
13	TF_AP4	after_TSS	8	GO:0051276 chromosome organization and biogenesis	13	220
14	MIT_060FOXO	before_TSS	7	GO:0006323 DNA packaging	17	188
15	TF_EGR1	before_TSS,after_TSS	7	GO:0051276 chromosome organization and biogenesis	14	220
16	TF_SP1	at_TSS,before_TSS,after_TSS	7	GO:0007049 cell cycle	50	443
17	TF_NFY	at_TSS,before_TSS	6	GO:0006259 DNA metabolism	44	427
18	MIT_015AP4	after_TSS	6	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)	15	208
19	TF_MAZR	at_TSS,before_TSS,after_TSS	5	GO:0006350 transcription	84	1461
20	TF_ETS	at_TSS	5	GO:0016887 ATPase activity	19	280
21	MIT_006SP1	at_TSS,before_TSS,after_TSS	5	GO:0007049 cell cycle	40	443
22	TF_ARNT	at_TSS,after_TSS	4	GO:0051301 cell division	17	134
23	TF_AP2	at_TSS,before_TSS	4	GO:0006350 transcription	82	1461
24	MIT_035MYOD	after_TSS	4	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)	12	208
25	TF_ATF6	at_TSS,after_TSS	3	GO:0009058 biosynthesis	53	878
26	MIT_024MAZ	at_TSS,before_TSS	3	GO:0000074 regulation of progression through cell cycle	26	246
27	TF_HTF	at_TSS,before_TSS	3	GO:0006259 DNA metabolism	28	427
28	MIT_073LEF	before_TSS	2	GO:0051276 chromosome organization and biogenesis	13	220
29	TF_COMP	at_TSS	2	GO:0006259 DNA metabolism	24	427
30	MIT_020E4F1	at_TSS	1	GO:0006457 protein folding	10	163

Details on Gene Ontology terms for targets of TF_E2F

Total number of genes = 12103

No.	In pair with	Multi- ple	Conser- ved	Location	Frequency in list	U-clusters in list	Genes with TFBS in list, %	Genes with TFBS total, %	Ratio	z	p	FDR	GO annotation
1	none	yes		after_TSS	166	2537	6.5	3.6	1.77	8.56	0	0	GO:0005634
2	none	yes		before_TSS	153	2537	6	3.6	1.64	7.086	0	0	GO:0005634
3	none	yes		after_TSS	146	2302	6.3	3.6	1.71	7.488	0	0	GO:0003676 nucleic acid binding
4	none	yes		after_TSS	142	2284	6.2	3.6	1.68	7.1	0	0	GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolism
5	none	yes		before_TSS	138	2284	6	3.6	1.64	6.668	0	0	GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolism
6	none			at_TSS	118	427	27.6	15	1.84	7.433	0	0	GO:0006259 DNA metabolism
7	none			at_TSS	117	443	26.4	15	1.75	6.842	0	0	GO:0007049 cell cycle
8	none			after_TSS	109	302	36	21.9	1.64	5.994	0	0	GO:0005667
9	none	yes		after_TSS	103	1509	6.8	3.6	1.84	6.895	0	0	GO:0003677 DNA binding
10	none		yes	at_TSS	96	941	10.2	6.3	1.59	4.997	0	0	GO:0030528 transcription regulator activity
11	none			at_TSS	87	354	24.5	15	1.63	5.112	0	0	GO:0003723 RNA binding
12	none		yes	at_TSS	82	852	9.6	6.3	1.5	4.02	0	0.0005	GO:0048513 organ development
13	none		yes	at_TSS	81	811	9.9	6.3	1.56	4.354	0	0.0002	GO:0009653 morphogenesis
14	none			after_TSS	80	220	36.3	21.9	1.65	5.196	0	0	GO:0051276 chromosome organization and biogenesis
15	none			after_TSS	74	208	35.5	21.9	1.61	4.773	0	0	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
16	none		yes	at_TSS	74	674	10.9	6.3	1.72	5.029	0	0	GO:0009887 organ morphogenesis
17	none		yes	at_TSS	71	719	9.8	6.3	1.54	3.955	0	0.0006	GO:0003700 transcription factor activity
18	none			after_TSS	67	188	35.6	21.9	1.62	4.555	0	0.0001	GO:0006323 DNA packaging
19	none			at_TSS	67	280	23.9	15	1.59	4.225	0	0.0043	GO:0016887 ATPase activity
20	none			before_TSS	67	220	30.4	19.4	1.56	4.142	0	0.0014	GO:0051276 chromosome organization and biogenesis
21	none		yes	before_TSS	66	852	7.7	4.9	1.57	3.977	0	0.0005	GO:0048513 organ development
22	none			at_TSS	64	246	26	15	1.73	4.881	0	0.0001	GO:0000074 regulation of progression through cell cycle
23	none			before_TSS	64	208	30.7	19.4	1.57	4.141	0	0.0014	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
24	none			after_TSS	64	179	35.7	21.9	1.62	4.48	0	0.0002	GO:0006325 establishment and/or maintenance of chromatin architecture
25	none			before_TSS	63	188	33.5	19.4	1.71	4.89	0	0	GO:0006323 DNA packaging
26	none			at_TSS	62	256	24.2	15	1.61	4.167	0	0.0112	GO:0042623 ATPase activity, coupled
27	none	yes		after_TSS	60	941	6.3	3.6	1.72	4.543	0	0.0001	GO:0030528 transcription regulator activity
28	none			before_TSS	58	179	32.4	19.4	1.66	4.393	0	0.0005	GO:0006325 establishment and/or maintenance of chromatin architecture
29	none			before_TSS	55	183	30	19.4	1.54	3.634	0.0002	0.017	GO:0030529
30	none		yes	at_TSS	54	538	10	6.3	1.57	3.552	0.0003	0.006	GO:0030154 cell differentiation
31	none			before_TSS	54	170	31.7	19.4	1.62	4.068	0	0.0014	GO:0009790 embryonic development
32	none			at_TSS	52	220	23.6	15	1.57	3.613	0.0003	0.0069	GO:0051276 chromosome organization and biogenesis
33	none			after_TSS	52	123	42.2	21.9	1.92	5.461	0	0	GO:0006461 protein complex assembly
34	none	yes		after_TSS	49	719	6.8	3.6	1.84	4.576	0	0.0002	GO:0003700 transcription factor activity
35	none	yes		before_TSS	49	839	5.8	3.6	1.58	3.451	0.0005	0.0292	GO:0016043 cell organization and biogenesis
36	none			after_TSS	48	121	39.6	21.9	1.8	4.72	0	0	GO:0006333 chromatin assembly or disassembly
37	none		yes	before_TSS	48	645	7.4	4.9	1.51	3.061	0.0022	0.0733	GO:0006996 organelle organization and biogenesis
38	none			at_TSS	47	208	22.5	15	1.5	3.088	0.002	0.0351	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
39	none			before_TSS	47	157	29.9	19.4	1.53	3.325	0.0008	0.0647	GO:0007167 enzyme linked receptor protein signaling pathway
40	none			at_TSS	47	159	29.5	15	1.96	5.169	0	0	GO:0009719 response to endogenous stimulus
41	none	yes		after_TSS	46	811	5.6	3.6	1.53	3.093	0.0019	0.0805	GO:0009653 morphogenesis
42	none			at_TSS	46	188	24.4	15	1.62	3.657	0.0002	0.0054	GO:0006323 DNA packaging
43	none			at_TSS	45	156	28.8	15	1.92	4.868	0	0	GO:0006974 response to DNA damage stimulus
44	none		yes	after_TSS	45	301	14.9	9.3	1.59	3.377	0.0007	0.0121	GO:0007399 nervous system development
45	none			before_TSS	44	123	35.7	19.4	1.83	4.581	0	0.0003	GO:0006461 protein complex assembly
46	none			before_TSS	43	121	35.5	19.4	1.82	4.478	0	0.0004	GO:0006333 chromatin assembly or disassembly
47	none			at_TSS	43	179	24	15	1.6	3.399	0.0006	0.0137	GO:0006325 establishment and/or maintenance of chromatin architecture
48	none	yes		after_TSS	42	427	9.8	3.6	2.66	6.852	0	0	GO:0006259 DNA metabolism
49	none			before_TSS	41	132	31	19.4	1.59	3.373	0.0007	0.0544	GO:0031324 negative regulation of cellular metabolism
50	none			after_TSS	41	95	43.1	21.9	1.96	5.002	0	0	GO:0031497 chromatin assembly
51	none			at_TSS	41	135	30.3	15	2.02	5.023	0	0	GO:0000278 mitotic cell cycle
52	none	yes		after_TSS	41	645	6.3	3.6	1.72	3.685	0.0002	0.0167	GO:0006996 organelle organization and biogenesis
53	none			after_TSS	40	86	46.5	21.9	2.11	5.511	0	0	GO:0006334 nucleosome assembly
54	none	yes		after_TSS	40	674	5.9	3.6	1.6	3.174	0.0015	0.0687	GO:0009887 organ morphogenesis
55	none	yes		before_TSS	39	645	6	3.6	1.64	3.286	0.001	0.0619	GO:0006996 organelle organization and biogenesis
56	none			before_TSS	39	121	32.2	19.4	1.65	3.555	0.0003	0.0276	GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
57	none		yes	at_TSS	39	301	12.9	6.3	2.03	4.729	0	0.0001	GO:0007399 nervous system development
58	none			at_TSS	39	133	29.3	15	1.95	4.645	0	0.0002	GO:0006281 DNA repair
59	none			at_TSS	39	163	23.9	15	1.59	3.207	0.0013	0.0258	GO:0006457 protein folding
60	none			at_TSS	38	122	31.1	15	2.07	5.014	0	0	GO:0000279 M phase
61	none			after_TSS	37	88	42	21.9	1.91	4.559	0	0.0001	GO:0005694
62	none			before_TSS	37	95	38.9	19.4	1.99	4.805	0	0.0001	GO:0031497 chromatin assembly
63	none			before_TSS	37	115	32.1	19.4	1.65	3.449	0.0005	0.0294	GO:0016481 negative regulation of transcription
64	none			at_TSS	36	132	27.2	15	1.81	3.964	0	0.0269	GO:0009165 nucleotide biosynthesis
65	none			at_TSS	35	90	38.8	15	2.59	6.364	0	0	GO:0006260 DNA replication
66	none			after_TSS	35	78	44.8	21.9	2.04	4.895	0	0	GO:0000786
67	none	yes		before_TSS	35	427	8.1	3.6	2.22	5.052	0	0	GO:0006259 DNA metabolism
68	none			at_TSS	34	108	31.4	15	2.09	4.812	0	0.0005	GO:0004386 helicase activity
69	none			before_TSS	34	86	39.5	19.4	2.02	4.708	0	0.0001	GO:0006334 nucleosome assembly
70	none			at_TSS	34	134	25.3	15	1.69	3.376	0.0007	0.0269	GO:0051301 cell division
71	none			at_TSS	33	125	26.4	15	1.75	3.582	0.0003	0.0155	GO:0000910 cytokinesis
72	none	yes		after_TSS	33	302	10.9	3.6	2.95	6.75	0	0	GO:0005667
73	none			before_TSS	33	88	37.5	19.4	1.92	4.28	0	0.0011	GO:0005694
74	none		yes	before_TSS	32	408	7.8	4.9	1.59	2.791	0.0052	0.06	GO:0048519 negative regulation of biological process
75	none			before_TSS	32	78	41	19.4	2.1	4.816	0	0	GO:0000786
76	none			at_TSS	31	121	25.6	15	1.7	3.282	0.001	0.0145	GO:0006333 chromatin assembly or disassembly
77	none		yes	at_TSS	30	302	9.9	6.3	1.55	2.56	0.0104	0.0608	GO:0005667
78	none		yes	before_TSS	30	342	8.7	4.9	1.78	3.355	0.0007	0.0181	GO:0043118 negative regulation of physiological process
79	none		yes	at_TSS	29	226	12.8	6.3	2.01	4.007	0	0.0225	GO:0008283 cell proliferation
80	none	yes		at_TSS	29	443	6.5	1.7	3.7	7.774	0	0	GO:0007049 cell cycle
81	none			at_TSS	29	86	33.7	15	2.24	4.874	0	0.0004	GO:0008026 ATP-dependent helicase activity
82	none		yes	after_TSS	29	156	18.5	9.3	1.98	3.987	0	0.0244	GO:0006974 response to DNA damage stimulus
83	none			before_TSS	29	82	35.3	19.4	1.81	3.641	0.0002	0.0248	GO:0045892 negative regulation of transcription, DNA-dependent
84	none		yes	before_TSS	29	330	8.7	4.9	1.79	3.307	0.0009	0.0215	GO:0051243 negative regulation of cellular physiological process
85	none		yes	after_TSS	29	159	18.2	9.3	1.95	3.873	0.0001	0.0393	GO:0009719 response to endogenous stimulus
86	none	yes		after_TSS	28	354	7.9	3.6	2.14	4.269	0	0.0005	GO:0003723 RNA binding
87	none	yes		before_TSS	27	408	6.6	3.6	1.79	3.21	0.0013	0.0485	GO:0048519 negative regulation of biological process
88	none	yes		before_TSS	26	342	7.6	3.6	2.06	3.913	0	0.0055	GO:0016070 RNA metabolism
89	none	yes		before_TSS	26	375	6.9	3.6	1.88	3.404	0.0006	0.0202	GO:0048523 negative regulation of cellular process
90	none			before_TSS	26	76	34.2	19.4	1.75	3.249	0.0011	0.047	GO:0007417 central nervous system development
91	none		yes	after_TSS	26	133	19.5	9.3	2.09	4.06	0	0.0179	GO:0006281 DNA repair
92	none			at_TSS	25	95	26.3	15	1.75	3.096	0.0019	0.0312	GO:0031497 chromatin assembly
93	none			at_TSS	25	89	28	15	1.87	3.466	0.0005	0.0276	GO:0000087 M phase of mitotic cell cycle
94	none		yes	after_TSS	25	134	18.6	9.3	1.99	3.719	0.0002	0.0732	GO:0051301 cell division
95	none		yes	after_TSS	25	128	19.5	9.3	2.08	3.975	0	0.0012	GO:0007389 pattern specification
96	none	yes		before_TSS	24	220	10.9	3.6	2.96	5.752	0	0	GO:0051276 chromosome organization and biogenesis
97	none			at_TSS	24	88	27.2	15	1.81	3.231	0.0012	0.0564	GO:0007067 mitosis
98	none			before_TSS	24	63	38	19.4	1.95	3.737	0.0001	0.017	GO:0007420 brain development
99	none			before_TSS	23	62	37	19.4	1.9	3.508	0.0004	0.0826	GO:0000122 negative regulation of transcription from RNA polymerase II promoter
100	none	yes		after_TSS	23	220	10.4	3.6	2.83	5.366	0	0	GO:0051276 chromosome organization and biogenesis
101	none	yes		before_TSS	23	330	6.9	3.6	1.89	3.222	0.0012	0.0665	GO:0051243 negative regulation of cellular physiological process
102	none	yes		before_TSS	23	208	11	3.6	3	5.705	0	0	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
103	none			at_TSS	22	86	25.5	15	1.7	2.753	0.0059	0.0831	GO:0006334 nucleosome assembly
104	none	yes		before_TSS	22	302	7.2	3.6	1.98	3.373	0.0007	0.0226	GO:0005667
105	none		yes	before_TSS	22	229	9.6	4.9	1.95	3.323	0.0008	0.0203	GO:0007610 behavior
106	none	yes		before_TSS	22	188	11.7	3.6	3.18	5.892	0	0	GO:0006323 DNA packaging
107	none	yes		after_TSS	21	208	10	3.6	2.73	4.938	0	0	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
108	none	yes		after_TSS	21	188	11.1	3.6	3.02	5.478	0	0	GO:0006323 DNA packaging
109	none	yes		before_TSS	21	273	7.6	3.6	2.09	3.565	0.0003	0.0166	GO:0006396 RNA processing
110	none	yes		before_TSS	21	179	11.7	3.6	3.19	5.769	0	0	GO:0006325 establishment and/or maintenance of chromatin architecture
111	none	yes		after_TSS	21	179	11.7	3.6	3.17	5.744	0	0	GO:0006325 establishment and/or maintenance of chromatin architecture
112	none	yes		after_TSS	21	301	6.9	3.6	1.88	3.058	0.0022	0.0741	GO:0007399 nervous system development
113	none	yes		before_TSS	20	202	9.9	3.6	2.69	4.74	0	0.0002	GO:0016071 mRNA metabolism
114	none	yes		after_TSS	19	273	6.9	3.6	1.88	2.894	0.0038	0.0556	GO:0006396 RNA processing
115	none			before_TSS	19	51	37.2	19.4	1.91	3.209	0.0013	0.0609	GO:0000785
116	none	yes		before_TSS	19	231	8.2	3.6	2.23	3.708	0.0002	0.0084	GO:0006366 transcription from RNA polymerase II promoter
117	none		yes	before_TSS	19	187	10.1	4.9	2.07	3.35	0.0008	0.0246	GO:0007626 locomotory behavior
118	none		yes	before_TSS	19	149	12.7	4.9	2.59	4.459	0	0.0007	GO:0009892 negative regulation of metabolism
119	none		yes	after_TSS	19	90	21.1	9.3	2.25	3.845	0.0001	0.0441	GO:0006260 DNA replication
120	none			at_TSS	18	58	31	15	2.06	3.424	0.0006	0.0282	GO:0005730
121	none		yes	before_TSS	18	137	13.1	4.9	2.67	4.484	0	0.0002	GO:0030182 neuron differentiation
122	none		yes	after_TSS	18	64	28.1	9.3	3	5.171	0	0	GO:0016564 transcriptional repressor activity
123	none	yes		after_TSS	18	231	7.7	3.6	2.1	3.335	0.0008	0.039	GO:0006366 transcription from RNA polymerase II promoter
124	none	yes		before_TSS	18	191	9.4	3.6	2.56	4.254	0	0.0019	GO:0006357 regulation of transcription from RNA polymerase II promoter
125	none		yes	before_TSS	17	128	13.2	4.9	2.7	4.408	0	0.0001	GO:0007389 pattern specification
126	none	yes		after_TSS	17	123	13.8	3.6	3.74	5.985	0	0	GO:0006461 protein complex assembly
127	none	yes		before_TSS	17	189	8.9	3.6	2.44	3.915	0	0.0082	GO:0006397 mRNA processing
128	none			at_TSS	17	32	53.1	15	3.53	6.043	0	0	GO:0006261 DNA-dependent DNA replication
129	none	yes		after_TSS	16	121	13.2	3.6	3.58	5.586	0	0	GO:0006333 chromatin assembly or disassembly
130	none		yes	before_TSS	16	165	9.6	4.9	1.97	2.867	0.0041	0.0561	GO:0040011 locomotion
131	none	yes		before_TSS	16	121	13.2	3.6	3.59	5.607	0	0	GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
132	none	yes		before_TSS	16	115	13.9	3.6	3.78	5.86	0	0	GO:0016481 negative regulation of transcription
133	none	yes		before_TSS	16	149	10.7	3.6	2.92	4.608	0	0.0014	GO:0009892 negative regulation of metabolism
134	none		yes	before_TSS	16	162	9.8	4.9	2.01	2.947	0.0032	0.0469	GO:0006928 cell motility
135	none		yes	after_TSS	16	81	19.7	9.3	2.11	3.225	0.0012	0.0512	GO:0007409 axonogenesis
136	none	yes		before_TSS	16	132	12.1	3.6	3.29	5.183	0	0	GO:0031324 negative regulation of cellular metabolism
137	none	yes		after_TSS	15	88	17	3.6	4.61	6.665	0	0	GO:0005694
138	none		yes	after_TSS	15	76	19.7	9.3	2.11	3.118	0.0018	0.0555	GO:0007417 central nervous system development
139	none	yes		before_TSS	15	149	10	3.6	2.73	4.17	0	0.0027	GO:0000375 RNA splicing, via transesterification reactions
140	none	yes		before_TSS	15	149	10	3.6	2.73	4.17	0	0.0027	GO:0000398 nuclear mRNA splicing, via spliceosome
141	none			at_TSS	15	39	38.4	15	2.56	4.106	0	0.0147	GO:0051321 meiotic cell cycle
142	none		yes	before_TSS	15	141	10.6	4.9	2.16	3.168	0.0015	0.0468	GO:0016477 cell migration
143	none	yes		before_TSS	15	149	10	3.6	2.73	4.17	0	0.0027	GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
144	none			at_TSS	15	39	38.4	15	2.56	4.106	0	0.0147	GO:0007126 meiosis
145	none	yes		after_TSS	15	86	17.4	3.6	4.72	6.784	0	0	GO:0006334 nucleosome assembly
146	none			at_TSS	15	39	38.4	15	2.56	4.106	0	0.0147	GO:0051327 M phase of meiotic cell cycle
147	none	yes		after_TSS	15	95	15.7	3.6	4.27	6.275	0	0	GO:0031497 chromatin assembly
148	none	yes		before_TSS	15	154	9.7	3.6	2.64	4.023	0	0.0052	GO:0008380 RNA splicing
149	none	yes		before_TSS	14	121	11.5	3.6	3.14	4.636	0	0.0002	GO:0006333 chromatin assembly or disassembly
150	none		yes	after_TSS	14	63	22.2	9.3	2.37	3.517	0.0004	0.0199	GO:0007420 brain development
151	none		yes	before_TSS	14	125	11.2	4.9	2.28	3.273	0.001	0.0973	GO:0000910 cytokinesis
152	none	yes		after_TSS	14	78	17.9	3.6	4.85	6.696	0	0	GO:0000786
153	none			before_TSS	14	31	45.1	19.4	2.31	3.612	0.0003	0.0556	GO:0030900 forebrain development
154	none			before_TSS	14	29	48.2	19.4	2.47	3.917	0	0.0328	GO:0007398 ectoderm development
155	none	yes		before_TSS	13	82	15.8	3.6	4.31	5.878	0	0	GO:0045892 negative regulation of transcription, DNA-dependent
156	none	yes		at_TSS	13	159	8.1	1.7	4.62	6.171	0	0	GO:0009719 response to endogenous stimulus
157	none	yes		at_TSS	13	156	8.3	1.7	4.71	6.262	0	0	GO:0006974 response to DNA damage stimulus
158	none		yes	before_TSS	13	108	12	4.9	2.45	3.444	0.0005	0.0174	GO:0048666 neuron development
159	none		yes	before_TSS	12	96	12.5	4.9	2.54	3.456	0.0005	0.0182	GO:0048667 neuron morphogensis during differentiation
160	none	yes		at_TSS	12	133	9	1.7	5.1	6.382	0	0	GO:0006281 DNA repair
161	none		yes	after_TSS	12	51	23.5	9.3	2.51	3.484	0.0004	0.0903	GO:0000785
162	none			at_TSS	12	24	50	15	3.33	4.803	0	0.0005	GO:0008094 DNA-dependent ATPase activity
163	none		yes	before_TSS	12	96	12.5	4.9	2.54	3.456	0.0005	0.0182	GO:0031175 neurite morphogenesis
164	none	yes		after_TSS	12	133	9	3.6	2.44	3.276	0.001	0.055	GO:0006281 DNA repair
165	none		yes	before_TSS	12	107	11.2	4.9	2.28	3.033	0.0024	0.0521	GO:0000904 cellular morphogenesis during differentiation
166	none		yes	at_TSS	12	76	15.7	6.3	2.47	3.367	0.0007	0.0309	GO:0007417 central nervous system development
167	none		yes	before_TSS	11	81	13.5	4.9	2.76	3.624	0.0002	0.0117	GO:0007409 axonogenesis
168	none	yes		before_TSS	11	62	17.7	3.6	4.82	5.899	0	0	GO:0000122 negative regulation of transcription from RNA polymerase II promoter
169	none		yes	at_TSS	11	61	18	6.3	2.82	3.734	0.0001	0.0229	GO:0035295 tube development
170	none			before_TSS	11	20	55	19.4	2.82	4.011	0	0.0221	GO:0009880 embryonic pattern specification
171	none		yes	at_TSS	10	53	18.8	6.3	2.95	3.728	0.0001	0.0706	GO:0019207 kinase regulator activity
172	none	yes		at_TSS	10	122	8.1	1.7	4.63	5.414	0	0	GO:0000279 M phase
173	none	yes		at_TSS	10	90	11.1	1.7	6.28	6.75	0	0	GO:0006260 DNA replication
174	ADD_LRH			after_TSS	18	208	8.6	1.8	4.57	7.219	0	0	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
175	ADD_LRH			after_TSS	18	220	8.1	1.8	4.32	6.91	0	0	GO:0051276 chromosome organization and biogenesis
176	ADD_LRH			after_TSS	17	179	9.4	1.8	5.01	7.523	0	0	GO:0006325 establishment and/or maintenance of chromatin architecture
177	ADD_LRH			after_TSS	17	188	9	1.8	4.77	7.252	0	0	GO:0006323 DNA packaging
178	ADD_LRH			after_TSS	13	121	10.7	1.8	5.67	7.182	0	0	GO:0006333 chromatin assembly or disassembly
179	ADD_LRH			after_TSS	12	123	9.7	1.8	5.15	6.433	0	0	GO:0006461 protein complex assembly
180	ADD_LRH			before_TSS	10	95	10.5	2	5.24	5.942	0	0	GO:0031497 chromatin assembly
181	ADD_LRH			before_TSS	10	86	11.6	2	5.79	6.382	0	0	GO:0006334 nucleosome assembly
182	ADD_LRH		yes	after_TSS	10	78	12.8	0.4	26.29	15.688	0	0	GO:0000786
183	ADD_LRH		yes	after_TSS	10	86	11.6	0.4	23.85	14.885	0	0	GO:0006334 nucleosome assembly
184	ADD_LRH			before_TSS	10	123	8.1	2	4.04	4.865	0	0.0006	GO:0006461 protein complex assembly
185	ADD_LRH			before_TSS	10	121	8.2	2	4.11	4.931	0	0.0003	GO:0006333 chromatin assembly or disassembly
186	ADD_LRH		yes	after_TSS	10	95	10.5	0.4	21.59	14.103	0	0	GO:0031497 chromatin assembly
187	MIT_006SP1			after_TSS	40	443	9	4.6	1.95	4.493	0	0.0758	GO:0007049 cell cycle
188	MIT_006SP1			at_TSS	35	246	14.2	6.5	2.16	4.89	0	0.0108	GO:0000074 regulation of progression through cell cycle
189	MIT_006SP1			before_TSS	21	231	9	3.6	2.47	4.426	0	0.0319	GO:0006366 transcription from RNA polymerase II promoter
190	MIT_006SP1	yes		at_TSS	19	246	7.7	2.7	2.85	4.907	0	0.0133	GO:0000074 regulation of progression through cell cycle
191	MIT_006SP1			before_TSS	19	191	9.9	3.6	2.71	4.652	0	0.0177	GO:0006357 regulation of transcription from RNA polymerase II promoter
192	MIT_006SP1			after_TSS	16	125	12.8	4.6	2.76	4.372	0	0.0665	GO:0000910 cytokinesis
193	MIT_015AP4			after_TSS	15	208	7.2	2.2	3.16	4.805	0	0.0012	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
194	MIT_015AP4			after_TSS	13	179	7.2	2.2	3.18	4.498	0	0.0046	GO:0006325 establishment and/or maintenance of chromatin architecture
195	MIT_015AP4			after_TSS	12	123	9.7	2.2	4.27	5.582	0	0	GO:0006461 protein complex assembly
196	MIT_015AP4			after_TSS	12	95	12.6	2.2	5.53	6.784	0	0	GO:0031497 chromatin assembly
197	MIT_015AP4			after_TSS	12	121	9.9	2.2	4.34	5.655	0	0	GO:0006333 chromatin assembly or disassembly
198	MIT_015AP4			after_TSS	12	86	13.9	2.2	6.11	7.277	0	0	GO:0006334 nucleosome assembly
199	MIT_015AP4			after_TSS	10	78	12.8	2.2	5.62	6.255	0	0	GO:0000786
200	MIT_020E4F1			at_TSS	10	163	6.1	1.1	5.15	5.862	0	0	GO:0006457 protein folding
201	MIT_024MAZ			before_TSS	26	427	6	3	2.01	3.78	0.0001	0.0954	GO:0006259 DNA metabolism
202	MIT_024MAZ			at_TSS	26	246	10.5	3	3.47	6.947	0	0	GO:0000074 regulation of progression through cell cycle
203	MIT_024MAZ			before_TSS	11	95	11.5	3	3.83	4.899	0	0.0004	GO:0031497 chromatin assembly
204	MIT_024MAZ			before_TSS	11	88	12.5	3	4.14	5.221	0	0	GO:0005694
205	MIT_035MYOD			after_TSS	12	208	5.7	1.5	3.77	5.028	0	0.0004	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
206	MIT_035MYOD			after_TSS	11	179	6.1	1.5	4.02	5.072	0	0.0003	GO:0006325 establishment and/or maintenance of chromatin architecture
207	MIT_035MYOD			after_TSS	11	188	5.8	1.5	3.82	4.868	0	0.0009	GO:0006323 DNA packaging
208	MIT_035MYOD			after_TSS	10	123	8.1	1.5	5.31	5.997	0	0	GO:0006461 protein complex assembly
209	MIT_045			after_TSS	15	179	8.3	2.5	3.34	5.069	0	0.0003	GO:0006325 establishment and/or maintenance of chromatin architecture
210	MIT_045			after_TSS	15	121	12.3	2.5	4.95	7	0	0	GO:0006333 chromatin assembly or disassembly
211	MIT_045			after_TSS	15	188	7.9	2.5	3.18	4.842	0	0.001	GO:0006323 DNA packaging
212	MIT_045			after_TSS	13	95	13.6	2.5	5.46	7.002	0	0	GO:0031497 chromatin assembly
213	MIT_045			after_TSS	12	86	13.9	2.5	5.57	6.82	0	0	GO:0006334 nucleosome assembly
214	MIT_045		yes	after_TSS	11	208	5.2	0.7	6.95	7.584	0	0	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
215	MIT_045			after_TSS	11	78	14.1	2.5	5.63	6.577	0	0	GO:0000786
216	MIT_045			after_TSS	11	88	12.5	2.5	4.99	6.024	0	0	GO:0005694
217	MIT_045		yes	after_TSS	11	220	5	0.7	6.57	7.306	0	0	GO:0051276 chromosome organization and biogenesis
218	MIT_045		yes	after_TSS	10	123	8.1	0.7	10.69	9.458	0	0	GO:0006461 protein complex assembly
219	MIT_060FOXO			before_TSS	17	188	9	2.8	3.17	5.141	0	0.0001	GO:0006323 DNA packaging
220	MIT_060FOXO			before_TSS	16	208	7.6	2.8	2.69	4.232	0	0.0125	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
221	MIT_060FOXO			before_TSS	15	179	8.3	2.8	2.93	4.478	0	0.0041	GO:0006325 establishment and/or maintenance of chromatin architecture
222	MIT_060FOXO			before_TSS	13	88	14.7	2.8	5.18	6.744	0	0	GO:0005694
223	MIT_060FOXO			before_TSS	12	121	9.9	2.8	3.47	4.694	0	0.0011	GO:0006333 chromatin assembly or disassembly
224	MIT_060FOXO			before_TSS	12	123	9.7	2.8	3.42	4.625	0	0.0018	GO:0006461 protein complex assembly
225	MIT_060FOXO			before_TSS	11	86	12.7	2.8	4.48	5.558	0	0	GO:0006334 nucleosome assembly
226	MIT_060FOXO			before_TSS	11	95	11.5	2.8	4.06	5.132	0	0.0001	GO:0031497 chromatin assembly
227	MIT_060FOXO			before_TSS	10	78	12.8	2.8	4.49	5.308	0	0	GO:0000786
228	MIT_073LEF			before_TSS	13	220	5.9	1.8	3.15	4.45	0	0.0053	GO:0051276 chromosome organization and biogenesis
229	MIT_073LEF			before_TSS	12	208	5.7	1.8	3.07	4.175	0	0.0155	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
230	MIT_092			after_TSS	11	95	11.5	0.6	17.3	13.092	0	0	GO:0031497 chromatin assembly
231	MIT_092			after_TSS	11	86	12.7	0.6	19.11	13.835	0	0	GO:0006334 nucleosome assembly
232	MIT_092			after_TSS	11	179	6.1	0.6	9.18	9.052	0	0	GO:0006325 establishment and/or maintenance of chromatin architecture
233	MIT_092			after_TSS	11	78	14.1	0.6	21.07	14.597	0	0	GO:0000786
234	MIT_092			after_TSS	11	208	5.2	0.6	7.9	8.241	0	0	GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
235	MIT_092			after_TSS	11	123	8.9	0.6	13.36	11.311	0	0	GO:0006461 protein complex assembly
236	MIT_092			after_TSS	11	188	5.8	0.6	8.74	8.782	0	0	GO:0006323 DNA packaging
237	MIT_092			after_TSS	11	220	5	0.6	7.47	7.95	0	0	GO:0051276 chromosome organization and biogenesis
238	MIT_092			after_TSS	11	121	9	0.6	13.58	11.418	0	0	GO:0006333 chromatin assembly or disassembly
239	MIT_092			after_TSS	10	88	11.3	0.6	16.97	12.348	0	0	GO:0005694
240	MIT_101			before_TSS	15	188	7.9	1.4	5.42	7.47	0	0	GO:0006323 DNA packaging
241	MIT_101			before_TSS	15	220	6.8	1.4	4.63	6.649	0	0	GO:0051276 chromosome organization and biogenesis
242