CisView Mouse (mm6, March 2005)

Main Gene Ontology terms for targets of TF_ELK

No.GO annotation
Total
genes
with GO
Location
Max no. of
genes with
TF_ELK
TF_ELK alone
In pair
with
1GO:0006412 protein biosynthesis
421
at_TSS,after_TSS
236
yes
many
2GO:0016070 RNA metabolism
342
at_TSS,before_TSS,after_TSS
197
yes
many
3GO:0044249 cellular biosynthesis
776
at_TSS,after_TSS
165
yes
MIT_012MYOD, TF_ETS,
4GO:0006396 RNA processing
273
at_TSS,before_TSS,after_TSS
156
yes
many
5GO:0019222 regulation of metabolism
1541
before_TSS
129
 
MIT_056PAX4,
6GO:0009059 macromolecule biosynthesis
472
at_TSS,after_TSS
126
yes
TF_ATF1, TF_ATF6, TF_ARNT,
7GO:0031323 regulation of cellular metabolism
1510
before_TSS
125
 
MIT_056PAX4,
8GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
1420
before_TSS
120
 
MIT_056PAX4,
9GO:0016301 kinase activity
684
before_TSS
120
yes
 
10GO:0003735 structural constituent of ribosome
172
at_TSS,after_TSS
120
yes
many
11GO:0045449 regulation of transcription
1410
before_TSS
119
 
MIT_056PAX4,
12GO:0006351 transcription, DNA-dependent
1383
before_TSS
115
 
MIT_056PAX4,
13GO:0006355 regulation of transcription, DNA-dependent
1362
before_TSS
114
 
MIT_056PAX4,
14GO:0005554 molecular function unknown
593
at_TSS
110
 
many
15GO:0030554 adenyl nucleotide binding
1036
at_TSS
108
 
MIT_005NFY, TF_E2F, TF_NFY,
16GO:0030528 transcription regulator activity
941
before_TSS,after_TSS
106
 
TF_AP2, TF_AP2A, MIT_056PAX4,
17GO:0009058 biosynthesis
878
after_TSS
106
 
MIT_012MYOD, TF_EGR1,
18GO:0005524 ATP binding
1011
at_TSS,before_TSS
105
 
many
19GO:0003723 RNA binding
354
at_TSS,before_TSS,after_TSS
100
yes
many
20GO:0016773 phosphotransferase activity, alcohol group as acceptor
553
before_TSS
98
yes
 
21GO:0009719 response to endogenous stimulus
159
at_TSS,after_TSS
95
yes
many
22GO:0008104 protein localization
508
at_TSS
94
yes
many
23GO:0006974 response to DNA damage stimulus
156
at_TSS,after_TSS
93
yes
TF_ATF6, TF_ETS, MIT_045,
24GO:0006259 DNA metabolism
427
at_TSS,before_TSS
93
yes
TF_SP1, TF_PBX,
25GO:0016310 phosphorylation
549
before_TSS
92
yes
 
26GO:0046907 intracellular transport
478
at_TSS
92
yes
many
27GO:0045184 establishment of protein localization
492
at_TSS,after_TSS
90
yes
many
28GO:0015031 protein transport
476
at_TSS,after_TSS
89
yes
many
29GO:0003677 DNA binding
1509
after_TSS
85
 
TF_AP2, TF_AP2A,
30GO:0004672 protein kinase activity
466
before_TSS
85
yes
 
31GO:0006468 protein amino acid phosphorylation
476
before_TSS
84
yes
 
32GO:0006281 DNA repair
133
at_TSS
83
yes
TF_CREB, TF_ETS,
33GO:0000166 nucleotide binding
1315
at_TSS
82
 
MIT_005NFY,
34GO:0004674 protein serine/threonine kinase activity
418
before_TSS
77
yes
 
35GO:0043037 translation
128
at_TSS,after_TSS
75
yes
many
36GO:0004713 protein-tyrosine kinase activity
381
before_TSS
70
yes
 
37GO:0006996 organelle organization and biogenesis
645
at_TSS
69
 
many
38GO:0016192 vesicle-mediated transport
228
at_TSS
69
yes
 
39GO:0007049 cell cycle
443
before_TSS
67
 
TF_SP1, TF_ELK, TF_ETS,
40GO:0006886 intracellular protein transport
350
at_TSS
67
yes
many
41GO:0003700 transcription factor activity
719
before_TSS
64
 
MIT_056PAX4,
42GO:0007028 cytoplasm organization and biogenesis
82
at_TSS
63
yes
many
43GO:0016071 mRNA metabolism
202
at_TSS,before_TSS,after_TSS
62
yes
many
44GO:0051082 unfolded protein binding
106
at_TSS
61
yes
many
45GO:0004386 helicase activity
108
at_TSS,before_TSS,after_TSS
61
yes
many
46GO:0042254 ribosome biogenesis and assembly
74
at_TSS,after_TSS
59
yes
many
47GO:0006397 mRNA processing
189
at_TSS,before_TSS,after_TSS
57
yes
many
48GO:0016043 cell organization and biogenesis
839
at_TSS
55
 
MIT_011GABP,
49GO:0016779 nucleotidyltransferase activity
91
at_TSS
55
yes
 
50GO:0007046 ribosome biogenesis
67
at_TSS
54
yes
many
51GO:0008270 zinc ion binding
901
at_TSS,after_TSS
53
 
TF_AP2, MIT_015AP4,
52GO:0006260 DNA replication
90
at_TSS
52
yes
many
53GO:0045182 translation regulator activity
90
at_TSS,after_TSS
52
yes
many
54GO:0019941 modification-dependent protein catabolism
94
at_TSS
51
yes
 
55GO:0006399 tRNA metabolism
86
at_TSS
51
yes
many
56GO:0006511 ubiquitin-dependent protein catabolism
94
at_TSS
51
yes
 
57GO:0008026 ATP-dependent helicase activity
86
at_TSS,before_TSS,after_TSS
51
yes
many
58GO:0008135 translation factor activity, nucleic acid binding
86
at_TSS,after_TSS
49
yes
many
59GO:0000398 nuclear mRNA splicing, via spliceosome
149
at_TSS,before_TSS,after_TSS
48
yes
many
60GO:0016567 protein ubiquitination
227
after_TSS
48
yes
 
61GO:0008380 RNA splicing
154
at_TSS,before_TSS,after_TSS
48
yes
many
62GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
149
at_TSS,before_TSS,after_TSS
48
yes
many
63GO:0000375 RNA splicing, via transesterification reactions
149
at_TSS,before_TSS,after_TSS
48
yes
many
64GO:0006605 protein targeting
141
at_TSS
46
yes
 
65GO:0016817 hydrolase activity, acting on acid anhydrides
450
at_TSS
44
 
TF_E2F,
66GO:0016462 pyrophosphatase activity
447
at_TSS
44
 
TF_E2F,
67GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
450
at_TSS
44
 
TF_E2F,
68GO:0017111 nucleoside-triphosphatase activity
429
at_TSS
43
 
TF_E2F,
69GO:0016887 ATPase activity
280
at_TSS,after_TSS
42
 
many
70GO:0009451 RNA modification
64
at_TSS
41
yes
many
71GO:0046903 secretion
123
at_TSS
40
yes
many
72GO:0006366 transcription from RNA polymerase II promoter
231
before_TSS
40
yes
 
73GO:0042623 ATPase activity, coupled
256
at_TSS,after_TSS
37
 
TF_ATF6, TF_E2F,
74GO:0006400 tRNA modification
57
at_TSS
37
yes
TF_RFX1,
75GO:0016886 ligase activity, forming phosphoric ester bonds
64
at_TSS
37
yes
TF_RFX1,
76GO:0003743 translation initiation factor activity
53
at_TSS,after_TSS
36
yes
many
77GO:0051301 cell division
134
before_TSS
36
yes
 
78GO:0006512 ubiquitin cycle
390
before_TSS
35
 
many
79GO:0008134 transcription factor binding
110
after_TSS
35
yes
 
80GO:0000910 cytokinesis
125
at_TSS,before_TSS
35
yes
TF_E2F,
81GO:0045045 secretory pathway
101
at_TSS
34
yes
TF_HTF, TF_ATF6, TF_ARNT,
82GO:0004812 tRNA ligase activity
55
at_TSS
33
yes
TF_RFX1, TF_AHR, TF_ETS,
83GO:0008452 RNA ligase activity
55
at_TSS
33
yes
TF_RFX1, TF_AHR, TF_ETS,
84GO:0016875 ligase activity, forming carbon-oxygen bonds
55
at_TSS
33
yes
TF_RFX1, TF_AHR, TF_ETS,
85GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds
55
at_TSS
33
yes
TF_RFX1, TF_AHR, TF_ETS,
86GO:0043038 amino acid activation
52
at_TSS
32
yes
TF_ETS,
87GO:0043039 tRNA aminoacylation
52
at_TSS
32
yes
TF_ETS,
88GO:0006418 tRNA aminoacylation for protein translation
52
at_TSS
32
yes
TF_ETS,
89GO:0005386 carrier activity
394
after_TSS
31
 
TF_RORA, TF_ER,
90GO:0007264 small GTPase mediated signal transduction
201
at_TSS
31
 
TF_SP1, MIT_070PAX3,
91GO:0008565 protein transporter activity
120
at_TSS
30
yes
TF_HTF, TF_ATF6, TF_ARNT,
92GO:0006913 nucleocytoplasmic transport
70
at_TSS
27
yes
 
93GO:0004518 nuclease activity
108
at_TSS
26
yes
MIT_021,
94GO:0007389 pattern specification
128
before_TSS
25
yes
 
95GO:0006457 protein folding
163
at_TSS,after_TSS
25
 
many
96GO:0016758 transferase activity, transferring hexosyl groups
109
before_TSS
25
yes
 
97GO:0016072 rRNA metabolism
31
at_TSS,after_TSS
25
yes
many
98GO:0008138 protein tyrosine/serine/threonine phosphatase activity
31
after_TSS
24
yes
 
99GO:0051169 nuclear transport
63
at_TSS
24
yes
 
100GO:0006364 rRNA processing
29
at_TSS
23
yes
many
101GO:0003899 DNA-directed RNA polymerase activity
30
at_TSS
22
yes
 
102GO:0007399 nervous system development
301
after_TSS
22
 
TF_AHR,
103GO:0048193 Golgi vesicle transport
30
at_TSS
20
yes
many

Pairs of TF_ELK binding sites with other TFBS

No.TFBS
Location
Total GO-s
Main GO annotation
N pairs for
main GO
Total genes
for main GO
1TF_ETS
at_TSS,before_TSS
35
GO:0044249 cellular biosynthesis
111
776
2TF_ELK
at_TSS,before_TSS,after_TSS
28
GO:0016070 RNA metabolism
85
342
3TF_HTF
at_TSS,before_TSS,after_TSS
25
GO:0046907 intracellular transport
87
478
4TF_ARNT
at_TSS,before_TSS,after_TSS
23
GO:0008104 protein localization
82
508
5TF_ATF1
at_TSS,before_TSS,after_TSS
20
GO:0046907 intracellular transport
90
478
6TF_GABP
at_TSS,after_TSS
19
GO:0003723 RNA binding
75
354
7TF_ATF6
at_TSS,before_TSS,after_TSS
18
GO:0046907 intracellular transport
84
478
8MIT_003ELK
at_TSS,after_TSS
18
GO:0006996 organelle organization and biogenesis
69
645
9TF_CREB
at_TSS,after_TSS
15
GO:0008104 protein localization
94
508
10TF_SP1
at_TSS,before_TSS
15
GO:0046907 intracellular transport
78
478
11TF_RFX1
at_TSS,after_TSS
14
GO:0016071 mRNA metabolism
25
202
12TF_E2F
at_TSS
13
GO:0030554 adenyl nucleotide binding
80
1036
13TF_AHR
at_TSS,after_TSS
13
GO:0005554 molecular function unknown
110
593
14MIT_006SP1
at_TSS,before_TSS
11
GO:0045184 establishment of protein localization
61
492
15MIT_056PAX4
before_TSS
9
GO:0019222 regulation of metabolism
129
1541
16TF_AP2
before_TSS,after_TSS
8
GO:0030528 transcription regulator activity
106
941
17TF_AP2A
before_TSS,after_TSS
7
GO:0003677 DNA binding
85
1509
18MIT_011GABP
at_TSS,after_TSS
7
GO:0016043 cell organization and biogenesis
55
839
19MIT_020E4F1
at_TSS
6
GO:0006996 organelle organization and biogenesis
42
645
20TF_RORA
after_TSS
6
GO:0005386 carrier activity
21
394
21MIT_024MAZ
at_TSS,before_TSS,after_TSS
5
GO:0045184 establishment of protein localization
61
492
22MIT_021
at_TSS
4
GO:0007028 cytoplasm organization and biogenesis
15
82
23TF_MYB
before_TSS
4
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
17
149
24TF_NFY
at_TSS
3
GO:0030554 adenyl nucleotide binding
108
1036
25TF_YY1
at_TSS,after_TSS
3
GO:0003735 structural constituent of ribosome
27
172
26MIT_005NFY
at_TSS
3
GO:0000166 nucleotide binding
82
1315
27TF_MYC
after_TSS
3
GO:0016887 ATPase activity
17
280
28MIT_002MYC
after_TSS
3
GO:0016887 ATPase activity
14
280
29MIT_045
at_TSS
2
GO:0009719 response to endogenous stimulus
10
159
30TF_EGR1
at_TSS,after_TSS
2
GO:0009058 biosynthesis
69
878
31MIT_070PAX3
at_TSS
2
GO:0007264 small GTPase mediated signal transduction
14
201
32MIT_055NFAT
at_TSS
2
GO:0006457 protein folding
17
163
33TF_NFKB
at_TSS
2
GO:0006260 DNA replication
12
90
34MIT_012MYOD
after_TSS
2
GO:0009058 biosynthesis
106
878
35TF_COMP
at_TSS
2
GO:0005554 molecular function unknown
38
593
36TF_STAT
before_TSS
1
GO:0006512 ubiquitin cycle
35
390
37MIT_081
after_TSS
1
GO:0045182 translation regulator activity
10
90
38TF_PAX4
at_TSS
1
GO:0005554 molecular function unknown
34
593
39MIT_022
at_TSS
1
GO:0006399 tRNA metabolism
11
86
40MIT_092
after_TSS
1
GO:0006457 protein folding
11
163
41TF_MRF2
before_TSS
1
GO:0042578 phosphoric ester hydrolase activity
16
222
42MIT_048NFKB
at_TSS
1
GO:0003723 RNA binding
18
354
43TF_CP2
before_TSS
1
GO:0035295 tube development
11
61
44TF_ER
after_TSS
1
GO:0005386 carrier activity
31
394
45MIT_068HSF
at_TSS
1
GO:0006457 protein folding
10
163
46MIT_031
at_TSS
1
GO:0005554 molecular function unknown
40
593
47MIT_015AP4
at_TSS
1
GO:0008270 zinc ion binding
53
901
48TF_PBX
at_TSS
1
GO:0006259 DNA metabolism
22
427
49TF_HSF
at_TSS
1
GO:0006457 protein folding
10
163
50TF_TST
before_TSS
1
GO:0000279 M phase
13
122
51MIT_106
at_TSS
1
GO:0003723 RNA binding
18
354
52MIT_008
at_TSS
1
GO:0003735 structural constituent of ribosome
12
172
53MIT_001NRF1
at_TSS
1
GO:0006996 organelle organization and biogenesis
44
645

Details on Gene Ontology terms for targets of TF_ELK

Total number of genes = 12103
No.In pair
with
Multi-
ple
Conser-
ved
Location
Frequency
in list
U-clusters
in list
Genes with TFBS
in list, %
Genes with TFBS
total, %
Ratio
z
p
FDR
GO annotation
1none
 
 
at_TSS
236
421
56
36
1.55
8.718
0
0
GO:0006412 protein biosynthesis
2none
yes
yes
at_TSS
205
2537
8
5.3
1.51
6.964
0
0
GO:0005634
3none
 
 
at_TSS
197
342
57.6
36
1.59
8.435
0
0
GO:0016070 RNA metabolism
4none
yes
 
at_TSS
165
776
21.2
13.5
1.57
6.54
0
0
GO:0044249 cellular biosynthesis
5none
 
 
at_TSS
156
273
57.1
36
1.58
7.354
0
0
GO:0006396 RNA processing
6none
 
 
at_TSS
127
183
69.3
36
1.92
9.478
0
0
GO:0030529
7none
yes
 
at_TSS
126
472
26.6
13.5
1.97
8.556
0
0
GO:0009059 macromolecule biosynthesis
8none
yes
 
at_TSS
123
421
29.2
13.5
2.16
9.603
0
0
GO:0006412 protein biosynthesis
9none
 
 
before_TSS
122
183
66.6
42.7
1.55
6.577
0
0
GO:0030529
10none
 
 
at_TSS
120
172
69.7
36
1.93
9.286
0
0
GO:0003735 structural constituent of ribosome
11none
 
yes
before_TSS
120
684
17.5
11.1
1.57
5.473
0
0
GO:0016301 kinase activity
12none
yes
 
at_TSS
109
342
31.8
13.5
2.36
10.084
0
0
GO:0016070 RNA metabolism
13none
yes
 
after_TSS
100
354
28.2
14
2
7.779
0
0
GO:0003723 RNA binding
14none
yes
 
at_TSS
99
354
27.9
13.5
2.07
8.082
0
0
GO:0003723 RNA binding
15none
 
yes
before_TSS
98
553
17.7
11.1
1.58
5.029
0
0.0001
GO:0016773 phosphotransferase activity, alcohol group as acceptor
16none
 
 
at_TSS
95
159
59.7
36
1.65
6.275
0
0
GO:0009719 response to endogenous stimulus
17none
 
 
at_TSS
95
136
69.8
36
1.93
8.266
0
0
GO:0005840
18none
 
 
at_TSS
93
156
59.6
36
1.65
6.179
0
0
GO:0006974 response to DNA damage stimulus
19none
yes
 
at_TSS
93
427
21.7
13.5
1.61
5.096
0
0
GO:0006259 DNA metabolism
20none
yes
 
after_TSS
93
342
27.1
14
1.93
7.073
0
0
GO:0016070 RNA metabolism
21none
 
yes
before_TSS
92
549
16.7
11.1
1.5
4.276
0
0.0069
GO:0016310 phosphorylation
22none
yes
 
after_TSS
92
421
21.8
14
1.55
4.667
0
0.0011
GO:0006412 protein biosynthesis
23none
yes
 
before_TSS
87
354
24.5
14.9
1.63
5.129
0
0
GO:0003723 RNA binding
24none
 
yes
before_TSS
85
466
18.2
11.1
1.63
4.962
0
0.0002
GO:0004672 protein kinase activity
25none
 
yes
before_TSS
84
476
17.6
11.1
1.58
4.598
0
0.0015
GO:0006468 protein amino acid phosphorylation
26none
yes
 
at_TSS
84
273
30.7
13.5
2.27
8.444
0
0
GO:0006396 RNA processing
27none
 
 
at_TSS
83
133
62.4
36
1.73
6.374
0
0
GO:0006281 DNA repair
28none
yes
 
after_TSS
77
273
28.2
14
2
6.787
0
0
GO:0006396 RNA processing
29none
 
yes
before_TSS
77
418
18.4
11.1
1.65
4.809
0
0.0005
GO:0004674 protein serine/threonine kinase activity
30none
yes
 
before_TSS
77
342
22.5
14.9
1.5
3.955
0
0.007
GO:0016070 RNA metabolism
31none
 
 
at_TSS
75
128
58.5
36
1.62
5.349
0
0
GO:0043037 translation
32none
 
yes
before_TSS
70
381
18.3
11.1
1.64
4.554
0
0.0019
GO:0004713 protein-tyrosine kinase activity
33none
 
yes
at_TSS
69
228
30.2
20.1
1.5
3.857
0.0001
0.021
GO:0016192 vesicle-mediated transport
34none
yes
 
at_TSS
67
288
23.2
13.5
1.72
4.906
0
0.0003
GO:0005794
35none
yes
 
at_TSS
66
172
38.3
13.5
2.84
9.613
0
0
GO:0003735 structural constituent of ribosome
36none
 
 
at_TSS
63
82
76.8
36
2.13
7.724
0
0
GO:0007028 cytoplasm organization and biogenesis
37none
yes
 
after_TSS
62
202
30.6
14
2.18
6.846
0
0
GO:0016071 mRNA metabolism
38none
yes
 
before_TSS
62
273
22.7
14.9
1.51
3.615
0.0003
0.0183
GO:0006396 RNA processing
39none
 
 
at_TSS
61
108
56.4
36
1.56
4.45
0
0.0015
GO:0004386 helicase activity
40none
 
 
at_TSS
61
106
57.5
36
1.59
4.638
0
0.0003
GO:0051082 unfolded protein binding
41none
 
 
at_TSS
59
74
79.7
36
2.21
7.857
0
0
GO:0042254 ribosome biogenesis and assembly
42none
yes
 
at_TSS
59
202
29.2
13.5
2.16
6.587
0
0
GO:0016071 mRNA metabolism
43none
yes
 
after_TSS
57
189
30.1
14
2.14
6.405
0
0
GO:0006397 mRNA processing
44none
 
 
at_TSS
55
91
60.4
36
1.67
4.871
0
0.0001
GO:0016779 nucleotidyltransferase activity
45none
yes
 
after_TSS
54
183
29.5
14
2.09
6.046
0
0
GO:0030529
46none
yes
yes
at_TSS
54
613
8.8
5.3
1.65
3.948
0
0.0288
GO:0005622
47none
 
 
at_TSS
54
67
80.5
36
2.23
7.622
0
0
GO:0007046 ribosome biogenesis
48none
yes
 
at_TSS
53
189
28
13.5
2.07
5.895
0
0
GO:0006397 mRNA processing
49none
 
 
at_TSS
52
90
57.7
36
1.6
4.316
0
0.0008
GO:0006260 DNA replication
50none
 
 
at_TSS
52
90
57.7
36
1.6
4.316
0
0.0004
GO:0045182 translation regulator activity
51none
 
 
at_TSS
51
86
59.3
36
1.64
4.514
0
0.0011
GO:0006399 tRNA metabolism
52none
 
 
at_TSS
51
94
54.2
36
1.5
3.698
0.0002
0.0159
GO:0019941 modification-dependent protein catabolism
53none
 
 
at_TSS
51
86
59.3
36
1.64
4.514
0
0.0007
GO:0008026 ATP-dependent helicase activity
54none
 
 
at_TSS
51
94
54.2
36
1.5
3.698
0.0002
0.0159
GO:0006511 ubiquitin-dependent protein catabolism
55none
 
 
at_TSS
49
86
56.9
36
1.58
4.063
0
0.0011
GO:0008135 translation factor activity, nucleic acid binding
56none
yes
 
after_TSS
48
227
21.1
14
1.5
3.089
0.002
0.0735
GO:0016567 protein ubiquitination
57none
yes
yes
at_TSS
48
478
10
5.3
1.88
4.691
0
0.0009
GO:0046907 intracellular transport
58none
yes
 
after_TSS
48
149
32.2
14
2.28
6.404
0
0
GO:0000375 RNA splicing, via transesterification reactions
59none
yes
 
after_TSS
48
149
32.2
14
2.28
6.404
0
0
GO:0000398 nuclear mRNA splicing, via spliceosome
60none
yes
 
before_TSS
48
202
23.7
14.9
1.58
3.523
0.0004
0.0312
GO:0016071 mRNA metabolism
61none
yes
 
after_TSS
48
154
31.1
14
2.21
6.136
0
0
GO:0008380 RNA splicing
62none
yes
 
after_TSS
48
149
32.2
14
2.28
6.404
0
0
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
63none
yes
yes
at_TSS
47
508
9.2
5.3
1.73
4.032
0
0.0067
GO:0008104 protein localization
64none
yes
yes
at_TSS
46
476
9.6
5.3
1.81
4.306
0
0.002
GO:0015031 protein transport
65none
 
yes
at_TSS
46
141
32.6
20.1
1.62
3.725
0.0001
0.0714
GO:0006605 protein targeting
66none
yes
yes
at_TSS
46
492
9.3
5.3
1.75
4.064
0
0.0058
GO:0045184 establishment of protein localization
67none
yes
 
at_TSS
46
128
35.9
13.5
2.66
7.467
0
0
GO:0043037 translation
68none
yes
 
at_TSS
44
154
28.5
13.5
2.11
5.507
0
0
GO:0008380 RNA splicing
69none
yes
 
before_TSS
44
189
23.2
14.9
1.55
3.218
0.0012
0.059
GO:0006397 mRNA processing
70none
yes
 
at_TSS
42
149
28.1
13.5
2.08
5.278
0
0
GO:0000398 nuclear mRNA splicing, via spliceosome
71none
yes
 
at_TSS
42
149
28.1
13.5
2.08
5.278
0
0
GO:0000375 RNA splicing, via transesterification reactions
72none
yes
 
at_TSS
42
149
28.1
13.5
2.08
5.278
0
0
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
73none
 
 
at_TSS
41
64
64
36
1.77
4.686
0
0.0003
GO:0009451 RNA modification
74none
 
 
after_TSS
41
54
75.9
44
1.72
4.734
0
0.0002
GO:0005681
75none
 
yes
before_TSS
40
231
17.3
11.1
1.55
3.008
0.0026
0.0534
GO:0006366 transcription from RNA polymerase II promoter
76none
 
yes
at_TSS
40
123
32.5
20.1
1.61
3.448
0.0005
0.0516
GO:0046903 secretion
77none
yes
 
before_TSS
39
154
25.3
14.9
1.68
3.616
0.0002
0.0156
GO:0008380 RNA splicing
78none
yes
 
before_TSS
38
149
25.5
14.9
1.7
3.618
0.0002
0.0181
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
79none
yes
 
before_TSS
38
149
25.5
14.9
1.7
3.618
0.0002
0.0181
GO:0000398 nuclear mRNA splicing, via spliceosome
80none
yes
 
before_TSS
38
149
25.5
14.9
1.7
3.618
0.0002
0.0181
GO:0000375 RNA splicing, via transesterification reactions
81none
yes
yes
at_TSS
38
350
10.8
5.3
2.04
4.682
0
0.0005
GO:0006886 intracellular protein transport
82none
 
 
at_TSS
37
58
63.7
36
1.77
4.417
0
0.0018
GO:0005730
83none
 
 
at_TSS
37
57
64.9
36
1.8
4.555
0
0.0006
GO:0006400 tRNA modification
84none
 
 
at_TSS
37
64
57.8
36
1.6
3.641
0.0002
0.0248
GO:0016886 ligase activity, forming phosphoric ester bonds
85none
 
 
at_TSS
36
54
66.6
36
1.85
4.702
0
0.0004
GO:0005681
86none
yes
 
at_TSS
36
82
43.9
13.5
3.25
8.083
0
0
GO:0007028 cytoplasm organization and biogenesis
87none
yes
 
before_TSS
36
134
26.8
14.9
1.79
3.873
0.0001
0.0393
GO:0051301 cell division
88none
 
 
after_TSS
36
53
67.9
44
1.54
3.514
0.0004
0.0403
GO:0003743 translation initiation factor activity
89none
yes
 
before_TSS
35
125
28
14.9
1.86
4.096
0
0.0153
GO:0000910 cytokinesis
90none
 
yes
after_TSS
35
110
31.8
19.3
1.64
3.341
0.0008
0.0611
GO:0008134 transcription factor binding
91none
yes
yes
at_TSS
34
183
18.5
5.3
3.49
8.051
0
0
GO:0030529
92none
yes
 
at_TSS
34
74
45.9
13.5
3.4
8.192
0
0
GO:0042254 ribosome biogenesis and assembly
93none
 
yes
at_TSS
34
101
33.6
20.1
1.67
3.409
0.0006
0.0596
GO:0045045 secretory pathway
94none
yes
 
before_TSS
34
108
31.4
14.9
2.1
4.823
0
0.0002
GO:0004386 helicase activity
95none
 
 
at_TSS
33
55
60
36
1.66
3.713
0.0002
0.0249
GO:0008452 RNA ligase activity
96none
 
 
at_TSS
33
55
60
36
1.66
3.713
0.0002
0.0249
GO:0016875 ligase activity, forming carbon-oxygen bonds
97none
 
 
at_TSS
33
55
60
36
1.66
3.713
0.0002
0.0249
GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds
98none
 
 
at_TSS
33
55
60
36
1.66
3.713
0.0002
0.0249
GO:0004812 tRNA ligase activity
99none
 
 
at_TSS
32
52
61.5
36
1.7
3.842
0.0001
0.0111
GO:0043039 tRNA aminoacylation
100none
 
 
at_TSS
32
52
61.5
36
1.7
3.842
0.0001
0.0111
GO:0006418 tRNA aminoacylation for protein translation
101none
yes
 
at_TSS
32
67
47.7
13.5
3.53
8.228
0
0
GO:0007046 ribosome biogenesis
102none
 
 
at_TSS
32
52
61.5
36
1.7
3.842
0.0001
0.0111
GO:0043038 amino acid activation
103none
 
 
at_TSS
32
53
60.3
36
1.67
3.702
0.0002
0.0391
GO:0019866
104none
yes
 
at_TSS
31
90
34.4
13.5
2.55
5.835
0
0
GO:0045182 translation regulator activity
105none
yes
 
at_TSS
30
86
34.8
13.5
2.58
5.823
0
0
GO:0008135 translation factor activity, nucleic acid binding
106none
yes
 
at_TSS
30
120
25
13.5
1.85
3.704
0.0002
0.0194
GO:0008565 protein transporter activity
107none
yes
 
at_TSS
30
86
34.8
13.5
2.58
5.823
0
0
GO:0006399 tRNA metabolism
108none
yes
 
at_TSS
29
90
32.2
13.5
2.38
5.216
0
0
GO:0006260 DNA replication
109none
yes
 
at_TSS
27
86
31.3
13.5
2.32
4.873
0
0.0002
GO:0008026 ATP-dependent helicase activity
110none
 
yes
at_TSS
27
70
38.5
20.1
1.91
3.862
0.0001
0.0411
GO:0006913 nucleocytoplasmic transport
111none
yes
 
after_TSS
27
90
30
14
2.13
4.358
0
0.0024
GO:0045182 translation regulator activity
112none
yes
 
after_TSS
26
86
30.2
14
2.14
4.322
0
0.0028
GO:0008135 translation factor activity, nucleic acid binding
113none
yes
 
at_TSS
26
108
24
13.5
1.78
3.229
0.0012
0.0757
GO:0004518 nuclease activity
114none
 
yes
before_TSS
25
128
19.5
11.1
1.75
3.03
0.0024
0.0186
GO:0007389 pattern specification
115none
yes
 
before_TSS
25
86
29
14.9
1.93
3.671
0.0002
0.0176
GO:0008026 ATP-dependent helicase activity
116none
 
 
at_TSS
25
31
80.6
36
2.23
5.182
0
0
GO:0016072 rRNA metabolism
117none
 
yes
before_TSS
25
109
22.9
11.1
2.05
3.928
0
0.0313
GO:0016758 transferase activity, transferring hexosyl groups
118none
yes
 
at_TSS
24
54
44.4
13.5
3.29
6.668
0
0
GO:0005681
119none
yes
 
at_TSS
24
64
37.5
13.5
2.77
5.632
0
0
GO:0009451 RNA modification
120none
 
 
after_TSS
24
31
77.4
44
1.75
3.751
0.0001
0.0644
GO:0008138 protein tyrosine/serine/threonine phosphatase activity
121none
 
yes
at_TSS
24
63
38
20.1
1.89
3.568
0.0003
0.0438
GO:0051169 nuclear transport
122none
 
 
at_TSS
23
29
79.3
36
2.2
4.862
0
0.0001
GO:0006364 rRNA processing
123none
 
 
at_TSS
22
30
73.3
36
2.03
4.262
0
0.0018
GO:0003899 DNA-directed RNA polymerase activity
124none
yes
 
at_TSS
21
57
36.8
13.5
2.72
5.168
0
0
GO:0006400 tRNA modification
125none
 
 
at_TSS
21
23
91.3
36
2.53
5.528
0
0
GO:0005830
126none
yes
yes
at_TSS
20
136
14.7
5.3
2.76
4.903
0
0.0003
GO:0005840
127none
 
 
at_TSS
20
30
66.6
36
1.85
3.501
0.0004
0.0848
GO:0048193 Golgi vesicle transport
128none
yes
 
after_TSS
20
74
27
14
1.91
3.212
0.0013
0.0964
GO:0042254 ribosome biogenesis and assembly
129none
yes
 
after_TSS
20
54
37
14
2.63
4.861
0
0.0002
GO:0005681
130none
yes
 
at_TSS
20
64
31.2
13.5
2.31
4.165
0
0.0113
GO:0016886 ligase activity, forming phosphoric ester bonds
131none
yes
 
at_TSS
19
52
36.5
13.5
2.7
4.871
0
0.0004
GO:0006418 tRNA aminoacylation for protein translation
132none
yes
 
at_TSS
19
53
35.8
13.5
2.65
4.771
0
0.0002
GO:0003743 translation initiation factor activity
133none
yes
 
at_TSS
19
55
34.5
13.5
2.55
4.577
0
0.0017
GO:0016875 ligase activity, forming carbon-oxygen bonds
134none
yes
 
at_TSS
19
55
34.5
13.5
2.55
4.577
0
0.0017
GO:0004812 tRNA ligase activity
135none
yes
 
at_TSS
19
52
36.5
13.5
2.7
4.871
0
0.0004
GO:0043038 amino acid activation
136none
 
 
at_TSS
19
28
67.8
36
1.88
3.513
0.0004
0.0405
GO:0000139
137none
yes
 
at_TSS
19
55
34.5
13.5
2.55
4.577
0
0.0017
GO:0008452 RNA ligase activity
138none
yes
 
at_TSS
19
52
36.5
13.5
2.7
4.871
0
0.0004
GO:0043039 tRNA aminoacylation
139none
yes
 
at_TSS
19
55
34.5
13.5
2.55
4.577
0
0.0017
GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds
140none
yes
 
after_TSS
18
53
33.9
14
2.41
4.17
0
0.0111
GO:0003743 translation initiation factor activity
141none
yes
 
before_TSS
18
54
33.3
14.9
2.22
3.784
0.0001
0.0188
GO:0005681
142none
 
 
at_TSS
18
26
69.2
36
1.92
3.531
0.0004
0.0252
GO:0051168 nuclear export
143none
 
 
at_TSS
17
24
70.8
36
1.96
3.556
0.0003
0.0459
GO:0008094 DNA-dependent ATPase activity
144none
 
 
at_TSS
17
24
70.8
36
1.96
3.556
0.0003
0.0689
GO:0007059 chromosome segregation
145none
yes
yes
at_TSS
16
123
13
5.3
2.44
3.817
0.0001
0.0164
GO:0046903 secretion
146none
yes
yes
at_TSS
15
101
14.8
5.3
2.79
4.285
0
0.0033
GO:0045045 secretory pathway
147none
yes
 
at_TSS
15
28
53.5
13.5
3.96
6.211
0
0
GO:0000139
148none
 
yes
at_TSS
14
23
60.8
20.1
3.02
4.879
0
0.0003
GO:0005802
149none
 
yes
before_TSS
14
53
26.4
11.1
2.36
3.539
0.0004
0.0245
GO:0016563 transcriptional activator activity
150none
yes
 
at_TSS
14
30
46.6
13.5
3.45
5.322
0
0
GO:0048193 Golgi vesicle transport
151none
yes
 
at_TSS
13
29
44.8
13.5
3.32
4.942
0
0
GO:0006364 rRNA processing
152none
yes
 
at_TSS
13
36
36.1
13.5
2.67
3.975
0
0.0064
GO:0006413 translational initiation
153none
yes
 
at_TSS
12
32
37.5
13.5
2.77
3.977
0
0.0255
GO:0006445 regulation of translation
154none
 
yes
at_TSS
11
21
52.3
20.1
2.6
3.69
0.0002
0.082
GO:0007369 gastrulation
155none
yes
 
at_TSS
11
32
34.3
13.5
2.54
3.459
0.0005
0.0496
GO:0008033 tRNA processing
156none
yes
 
at_TSS
11
24
45.8
13.5
3.39
4.639
0
0.0006
GO:0008094 DNA-dependent ATPase activity
157none
yes
 
at_TSS
10
26
38.4
13.5
2.84
3.728
0.0001
0.0141
GO:0051168 nuclear export
158MIT_001NRF1
 
 
at_TSS
44
645
6.8
3.6
1.87
4.426
0
0.0129
GO:0006996 organelle organization and biogenesis
159MIT_002MYC
 
 
after_TSS
14
280
5
1.5
3.27
4.79
0
0.024
GO:0016887 ATPase activity
160MIT_002MYC
 
 
after_TSS
11
98
11.2
1.5
7.34
7.855
0
0
GO:0008168 methyltransferase activity
161MIT_002MYC
 
 
after_TSS
11
101
10.8
1.5
7.12
7.701
0
0
GO:0016741 transferase activity, transferring one-carbon groups
162MIT_003ELK
 
 
at_TSS
69
645
10.6
6.6
1.6
4.194
0
0.0275
GO:0006996 organelle organization and biogenesis
163MIT_003ELK
 
 
at_TSS
58
354
16.3
6.6
2.45
7.416
0
0
GO:0003723 RNA binding
164MIT_003ELK
 
 
at_TSS
29
128
22.6
6.6
3.38
7.273
0
0
GO:0043037 translation
165MIT_003ELK
yes
 
at_TSS
26
183
14.2
3.5
3.98
7.816
0
0
GO:0030529
166MIT_003ELK
 
 
at_TSS
24
74
32.4
6.6
4.85
8.895
0
0
GO:0042254 ribosome biogenesis and assembly
167MIT_003ELK
 
 
at_TSS
24
82
29.2
6.6
4.37
8.216
0
0
GO:0007028 cytoplasm organization and biogenesis
168MIT_003ELK
 
 
at_TSS
24
154
15.5
6.6
2.33
4.45
0
0.0463
GO:0008380 RNA splicing
169MIT_003ELK
 
 
at_TSS
22
67
32.8
6.6
4.91
8.594
0
0
GO:0007046 ribosome biogenesis
170MIT_003ELK
 
 
at_TSS
19
90
21.1
6.6
3.15
5.5
0
0.0001
GO:0045182 translation regulator activity
171MIT_003ELK
 
 
after_TSS
18
202
8.9
2.1
4.14
6.685
0
0
GO:0016071 mRNA metabolism
172MIT_003ELK
 
 
at_TSS
18
86
20.9
6.6
3.13
5.308
0
0.0003
GO:0008135 translation factor activity, nucleic acid binding
173MIT_003ELK
 
 
after_TSS
16
189
8.4
2.1
3.94
6.037
0
0
GO:0006397 mRNA processing
174MIT_003ELK
 
 
after_TSS
14
149
9.3
2.1
4.37
6.139
0
0
GO:0000375 RNA splicing, via transesterification reactions
175MIT_003ELK
 
 
after_TSS
14
149
9.3
2.1
4.37
6.139
0
0
GO:0000398 nuclear mRNA splicing, via spliceosome
176MIT_003ELK
 
 
after_TSS
14
149
9.3
2.1
4.37
6.139
0
0
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
177MIT_003ELK
 
 
after_TSS
14
154
9
2.1
4.23
5.98
0
0
GO:0008380 RNA splicing
178MIT_003ELK
 
 
at_TSS
12
53
22.6
6.6
3.38
4.661
0
0.0123
GO:0003743 translation initiation factor activity
179MIT_003ELK
 
 
at_TSS
11
31
35.4
6.6
5.3
6.428
0
0
GO:0016072 rRNA metabolism
180MIT_003ELK
 
 
at_TSS
10
29
34.4
6.6
5.15
6
0
0
GO:0006364 rRNA processing
181MIT_003ELK
 
 
at_TSS
10
36
27.7
6.6
4.15
5.074
0
0.0056
GO:0006413 translational initiation
182MIT_005NFY
 
 
at_TSS
82
1315
6.2
3.9
1.56
4.405
0
0.0653
GO:0000166 nucleotide binding
183MIT_005NFY
 
 
at_TSS
74
1036
7.1
3.9
1.78
5.42
0
0.0008
GO:0030554 adenyl nucleotide binding
184MIT_005NFY
 
 
at_TSS
72
1011
7.1
3.9
1.78
5.312
0
0.0015
GO:0005524 ATP binding
185MIT_006SP1
 
yes
at_TSS
61
492
12.3
6.1
2.01
5.87
0
0
GO:0045184 establishment of protein localization
186MIT_006SP1
 
 
before_TSS
57
354
16.1
8
2
5.653
0
0.0006
GO:0003723 RNA binding
187MIT_006SP1
 
yes
at_TSS
56
478
11.7
6.1
1.9
5.149
0
0.0016
GO:0046907 intracellular transport
188MIT_006SP1
 
yes
at_TSS
48
350
13.7
6.1
2.22
5.96
0
0
GO:0006886 intracellular protein transport
189MIT_006SP1
 
yes
at_TSS
37
288
12.8
6.1
2.08
4.773
0
0.0098
GO:0005794
190MIT_006SP1
 
 
at_TSS
35
108
32.4
16.5
1.96
4.46
0
0.0272
GO:0004386 helicase activity
191MIT_006SP1
yes
 
before_TSS
15
149
10
3.2
3.05
4.657
0
0.0154
GO:0000398 nuclear mRNA splicing, via spliceosome
192MIT_006SP1
yes
 
before_TSS
15
149
10
3.2
3.05
4.657
0
0.0154
GO:0000375 RNA splicing, via transesterification reactions
193MIT_006SP1
yes
 
before_TSS
15
149
10
3.2
3.05
4.657
0
0.0154
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
194MIT_006SP1
 
 
at_TSS
15
30
50
16.5
3.02
4.94
0
0.0112
GO:0048193 Golgi vesicle transport
195MIT_006SP1
yes
 
before_TSS
15
154
9.7
3.2
2.95
4.507
0
0.0284
GO:0008380 RNA splicing
196MIT_006SP1
 
 
at_TSS
13
24
54.1
16.5
3.27
4.967
0
0.0293
GO:0008094 DNA-dependent ATPase activity
197MIT_006SP1
 
 
at_TSS
13
28
46.4
16.5
2.8
4.263
0
0.0968
GO:0000139
198MIT_008
 
 
at_TSS
12
172
6.9
0.6
10.42
10.218
0
0
GO:0003735 structural constituent of ribosome
199MIT_008
 
 
at_TSS
11
136
8
0.6
12.08
10.671
0
0
GO:0005840
200MIT_011GABP
 
 
at_TSS
55
839
6.5
3.8
1.69
4.203
0
0.0406
GO:0016043 cell organization and biogenesis
201MIT_011GABP
 
 
at_TSS
49
645
7.5
3.8
1.96
5.066
0
0.001
GO:0006996 organelle organization and biogenesis
202MIT_011GABP
 
 
after_TSS
15
273
5.4
1.1
4.75
6.779
0
0
GO:0006396 RNA processing
203MIT_011GABP
yes
 
at_TSS
11
74
14.8
1.7
8.64
8.727
0
0
GO:0042254 ribosome biogenesis and assembly
204MIT_011GABP
yes
 
at_TSS
11
82
13.4
1.7
7.8
8.176
0
0
GO:0007028 cytoplasm organization and biogenesis
205MIT_011GABP
 
 
at_TSS
10
64
15.6
3.8
4.04
4.9
0
0.0051
GO:0009451 RNA modification
206MIT_011GABP
yes
 
at_TSS
10
67
14.9
1.7
8.68
8.34
0
0
GO:0007046 ribosome biogenesis
207MIT_012MYOD
 
 
after_TSS
106
878
12
7.6
1.58
5.191
0
0.009
GO:0009058 biosynthesis
208MIT_012MYOD
 
 
after_TSS
93
776
11.9
7.6
1.57
4.762
0
0.0207
GO:0044249 cellular biosynthesis
209MIT_015AP4
 
 
at_TSS
53
901
5.8
3.2
1.78
4.537
0
0.0616
GO:0008270 zinc ion binding
210MIT_020E4F1
 
 
at_TSS
42
645
6.5
3.4
1.87
4.32
0
0.0187
GO:0006996 organelle organization and biogenesis
211MIT_020E4F1
 
 
at_TSS
17
163
10.4
3.4
2.99
4.875
0
0.0029
GO:0006457 protein folding
212MIT_020E4F1
 
 
at_TSS
15
74
20.2
3.4
5.82
7.907
0
0
GO:0042254 ribosome biogenesis and assembly
213MIT_020E4F1
 
 
at_TSS
14
106
13.2
3.4
3.79
5.49
0
0.0001
GO:0051082 unfolded protein binding
214MIT_020E4F1
 
 
at_TSS
11
86
12.7
3.4
3.67
4.729
0
0.0046
GO:0008135 translation factor activity, nucleic acid binding
215MIT_020E4F1
 
 
at_TSS
11
90
12.2
3.4
3.51
4.543
0
0.0099
GO:0045182 translation regulator activity
216MIT_021
 
 
at_TSS
15
82
18.2
2.7
6.68
8.666
0
0
GO:0007028 cytoplasm organization and biogenesis
217MIT_021
 
 
at_TSS
14
74
18.9
2.7
6.91
8.561
0
0
GO:0042254 ribosome biogenesis and assembly
218MIT_021
 
 
at_TSS
13
67
19.4
2.7
7.09
8.388
0
0
GO:0007046 ribosome biogenesis
219MIT_021
 
 
at_TSS
11
108
10.1
2.7
3.72
4.768
0
0.0804
GO:0004518 nuclease activity
220MIT_022
 
 
at_TSS
11
86
12.7
3.5
3.62
4.672
0
0.0214
GO:0006399 tRNA metabolism
221MIT_024MAZ
 
 
after_TSS
61
492
12.3
7.2
1.72
4.548
0
0.078
GO:0045184 establishment of protein localization
222MIT_024MAZ
 
 
after_TSS
60
476
12.6
7.2
1.74
4.648