CisView Mouse (mm6, March 2005)

Main Gene Ontology terms for targets of TF_FOXO

No.GO annotation
Total
genes
with GO
Location
Max no. of
genes with
TF_FOXO
TF_FOXO alone
In pair
with
1GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
1420
before_TSS
97
yes
 
2GO:0045449 regulation of transcription
1410
before_TSS
96
yes
 
3GO:0006351 transcription, DNA-dependent
1383
before_TSS
95
yes
 
4GO:0006355 regulation of transcription, DNA-dependent
1362
before_TSS
94
yes
 
5GO:0030528 transcription regulator activity
941
before_TSS
71
yes
 
6GO:0003700 transcription factor activity
719
before_TSS
59
yes
 
7GO:0009653 morphogenesis
811
before_TSS
55
yes
 
8GO:0009887 organ morphogenesis
674
before_TSS
48
yes
 
9GO:0009607 response to biotic stimulus
483
at_TSS
42
yes
 
10GO:0006952 defense response
463
at_TSS
40
yes
 
11GO:0006955 immune response
379
at_TSS
32
yes
 
12GO:0004857 enzyme inhibitor activity
155
after_TSS
26
yes
 
13GO:0016788 hydrolase activity, acting on ester bonds
448
before_TSS
26
 
MIT_060FOXO,
14GO:0016192 vesicle-mediated transport
228
before_TSS
23
yes
 
15GO:0004866 endopeptidase inhibitor activity
112
after_TSS
21
yes
 
16GO:0030414 protease inhibitor activity
112
after_TSS
21
yes
 
17GO:0007399 nervous system development
301
at_TSS
16
yes
 
18GO:0048522 positive regulation of cellular process
292
after_TSS
16
yes
 
19GO:0008236 serine-type peptidase activity
158
at_TSS
15
yes
 
20GO:0004252 serine-type endopeptidase activity
140
at_TSS
15
yes
 
21GO:0004867 serine-type endopeptidase inhibitor activity
77
after_TSS
15
yes
 
22GO:0043119 positive regulation of physiological process
273
after_TSS
14
yes
 
23GO:0051242 positive regulation of cellular physiological process
266
after_TSS
14
yes
 
24GO:0006897 endocytosis
116
before_TSS
14
yes
 
25GO:0007389 pattern specification
128
before_TSS
12
yes
 
26GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
93
at_TSS
11
yes
 
27GO:0004263 chymotrypsin activity
90
at_TSS
11
yes
 
28GO:0004295 trypsin activity
101
at_TSS
11
yes
 
29GO:0050953 sensory perception of light
64
before_TSS
10
 
TF_AHR,
30GO:0005529 sugar binding
144
before_TSS
10
 
TF_YY1,
31GO:0007601 visual perception
64
before_TSS
10
 
TF_AHR,
32GO:0001501 skeletal development
87
before_TSS
10
yes
 
33GO:0006357 regulation of transcription from RNA polymerase II promoter
191
after_TSS
10
yes
 

Pairs of TF_FOXO binding sites with other TFBS

No.TFBS
Location
Total GO-s
Main GO annotation
N pairs for
main GO
Total genes
for main GO
1TF_AHR
before_TSS
2
GO:0007601 visual perception
10
64
2TF_YY1
before_TSS
1
GO:0005529 sugar binding
10
144
3MIT_060FOXO
before_TSS
1
GO:0016788 hydrolase activity, acting on ester bonds
26
448

Details on Gene Ontology terms for targets of TF_FOXO

Total number of genes = 12103
No.In pair
with
Multi-
ple
Conser-
ved
Location
Frequency
in list
U-clusters
in list
Genes with TFBS
in list, %
Genes with TFBS
total, %
Ratio
z
p
FDR
GO annotation
1none
 
yes
before_TSS
97
1420
6.8
4.4
1.52
4.542
0
0
GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
2none
 
yes
before_TSS
96
1410
6.8
4.4
1.51
4.48
0
0
GO:0045449 regulation of transcription
3none
 
yes
before_TSS
95
1383
6.8
4.4
1.53
4.547
0
0
GO:0006351 transcription, DNA-dependent
4none
 
yes
before_TSS
94
1362
6.9
4.4
1.53
4.57
0
0
GO:0006355 regulation of transcription, DNA-dependent
5none
 
yes
before_TSS
71
941
7.5
4.4
1.68
4.719
0
0
GO:0030528 transcription regulator activity
6none
 
yes
before_TSS
59
719
8.2
4.4
1.82
4.967
0
0
GO:0003700 transcription factor activity
7none
 
yes
before_TSS
55
811
6.7
4.4
1.51
3.268
0.001
0.0047
GO:0009653 morphogenesis
8none
 
yes
before_TSS
48
674
7.1
4.4
1.58
3.4
0.0006
0.0032
GO:0009887 organ morphogenesis
9none
 
 
at_TSS
42
483
8.6
4.6
1.88
4.381
0
0.0002
GO:0009607 response to biotic stimulus
10none
 
 
at_TSS
40
463
8.6
4.6
1.87
4.227
0
0.0003
GO:0006952 defense response
11none
 
 
at_TSS
32
379
8.4
4.6
1.83
3.625
0.0002
0.004
GO:0006955 immune response
12none
 
 
after_TSS
26
155
16.7
7.9
2.1
4.076
0
0.0055
GO:0004857 enzyme inhibitor activity
13none
 
 
at_TSS
26
356
7.3
4.6
1.58
2.468
0.0135
0.0815
GO:0005576
14none
 
yes
before_TSS
24
302
7.9
4.4
1.77
2.941
0.0032
0.0131
GO:0005667
15none
 
yes
before_TSS
23
228
10
4.4
2.24
4.124
0
0.0136
GO:0016192 vesicle-mediated transport
16none
 
 
after_TSS
21
112
18.7
7.9
2.35
4.235
0
0.0027
GO:0030414 protease inhibitor activity
17none
 
yes
at_TSS
21
302
6.9
1.8
3.67
6.537
0
0
GO:0005667
18none
 
 
after_TSS
21
112
18.7
7.9
2.35
4.235
0
0.0027
GO:0004866 endopeptidase inhibitor activity
19none
 
yes
after_TSS
16
292
5.4
1.9
2.82
4.434
0
0.0033
GO:0048522 positive regulation of cellular process
20none
 
yes
at_TSS
16
301
5.3
1.8
2.8
4.414
0
0.0003
GO:0007399 nervous system development
21none
 
 
after_TSS
15
77
19.4
7.9
2.44
3.743
0.0001
0.0073
GO:0004867 serine-type endopeptidase inhibitor activity
22none
 
 
at_TSS
15
158
9.4
4.6
2.06
2.953
0.0031
0.0767
GO:0008236 serine-type peptidase activity
23none
 
 
at_TSS
15
140
10.7
4.6
2.32
3.471
0.0005
0.0189
GO:0004252 serine-type endopeptidase activity
24none
 
 
before_TSS
14
23
60.8
27.8
2.18
3.533
0.0004
0.0751
GO:0005802
25none
 
yes
before_TSS
14
116
12
4.4
2.69
3.963
0
0.0135
GO:0006897 endocytosis
26none
 
yes
after_TSS
14
273
5.1
1.9
2.64
3.859
0.0001
0.0416
GO:0043119 positive regulation of physiological process
27none
 
yes
after_TSS
14
266
5.2
1.9
2.71
3.969
0
0.0264
GO:0051242 positive regulation of cellular physiological process
28none
 
yes
before_TSS
12
128
9.3
4.4
2.08
2.685
0.0072
0.0408
GO:0007389 pattern specification
29none
 
 
at_TSS
11
93
11.8
4.6
2.57
3.338
0.0008
0.0441
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
30none
 
 
at_TSS
11
101
10.8
4.6
2.36
3.028
0.0024
0.045
GO:0004295 trypsin activity
31none
 
 
at_TSS
11
90
12.2
4.6
2.65
3.462
0.0005
0.0122
GO:0004263 chymotrypsin activity
32none
 
yes
after_TSS
10
191
5.2
1.9
2.69
3.325
0.0008
0.0359
GO:0006357 regulation of transcription from RNA polymerase II promoter
33none
 
yes
before_TSS
10
87
11.4
4.4
2.56
3.168
0.0015
0.0468
GO:0001501 skeletal development
34MIT_060FOXO
yes
 
before_TSS
26
448
5.8
2.4
2.34
4.631
0
0.0786
GO:0016788 hydrolase activity, acting on ester bonds
35TF_AHR
 
 
before_TSS
10
64
15.6
3.2
4.86
5.644
0
0.0007
GO:0050953 sensory perception of light
36TF_AHR
 
 
before_TSS
10
64
15.6
3.2
4.86
5.644
0
0.0007
GO:0007601 visual perception
37TF_YY1
 
 
before_TSS
10
144
6.9
2
3.34
4.125
0
0.05
GO:0005529 sugar binding