CisView Mouse (mm6, March 2005)

Main Gene Ontology terms for targets of TF_GABP

No.GO annotation
Total
genes
with GO
Location
Max no. of
genes with
TF_GABP
TF_GABP alone
In pair
with
1GO:0009059 macromolecule biosynthesis
472
at_TSS
195
yes
MIT_003ELK,
2GO:0006412 protein biosynthesis
421
at_TSS
183
yes
 
3GO:0016070 RNA metabolism
342
at_TSS,before_TSS,after_TSS
156
yes
many
4GO:0003723 RNA binding
354
at_TSS,before_TSS,after_TSS
141
yes
many
5GO:0006396 RNA processing
273
at_TSS,after_TSS
126
yes
many
6GO:0016071 mRNA metabolism
202
at_TSS,after_TSS
95
yes
TF_RFX1, TF_GABP, TF_ELK,
7GO:0003735 structural constituent of ribosome
172
at_TSS
91
yes
many
8GO:0006397 mRNA processing
189
at_TSS,before_TSS,after_TSS
88
yes
TF_GABP, TF_ELK,
9GO:0016772 transferase activity, transferring phosphorus-containing groups
787
at_TSS
87
 
TF_SP1,
10GO:0005554 molecular function unknown
593
at_TSS
78
 
TF_AHR,
11GO:0008380 RNA splicing
154
at_TSS,after_TSS
76
yes
many
12GO:0000398 nuclear mRNA splicing, via spliceosome
149
at_TSS,before_TSS,after_TSS
75
yes
MIT_003ELK, TF_GABP, TF_ELK,
13GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
149
at_TSS,before_TSS,after_TSS
75
yes
MIT_003ELK, TF_GABP, TF_ELK,
14GO:0000375 RNA splicing, via transesterification reactions
149
at_TSS,before_TSS,after_TSS
75
yes
MIT_003ELK, TF_GABP, TF_ELK,
15GO:0008104 protein localization
508
at_TSS
72
yes
many
16GO:0009058 biosynthesis
878
after_TSS
70
 
MIT_012MYOD,
17GO:0045184 establishment of protein localization
492
at_TSS
69
yes
many
18GO:0006457 protein folding
163
at_TSS
68
yes
MIT_055NFAT, TF_GABP, TF_ELK,
19GO:0015031 protein transport
476
at_TSS
67
yes
many
20GO:0046907 intracellular transport
478
at_TSS
66
yes
many
21GO:0006974 response to DNA damage stimulus
156
at_TSS,after_TSS
65
yes
 
22GO:0009719 response to endogenous stimulus
159
at_TSS,after_TSS
65
yes
TF_NFY,
23GO:0043037 translation
128
at_TSS,after_TSS
65
yes
MIT_003ELK, TF_ELK, TF_ETS,
24GO:0006281 DNA repair
133
at_TSS,after_TSS
59
yes
 
25GO:0006996 organelle organization and biogenesis
645
at_TSS
57
 
MIT_003ELK, TF_GABP, TF_ETS,
26GO:0007049 cell cycle
443
before_TSS
55
yes
 
27GO:0016192 vesicle-mediated transport
228
at_TSS
52
yes
many
28GO:0007028 cytoplasm organization and biogenesis
82
at_TSS
49
yes
many
29GO:0006886 intracellular protein transport
350
at_TSS
49
yes
many
30GO:0016779 nucleotidyltransferase activity
91
at_TSS
48
yes
TF_AHR, TF_SP1, MIT_006SP1,
31GO:0051082 unfolded protein binding
106
at_TSS,before_TSS
48
yes
many
32GO:0016741 transferase activity, transferring one-carbon groups
101
after_TSS
46
yes
TF_ATF6, TF_ARNT,
33GO:0004386 helicase activity
108
at_TSS,after_TSS
46
yes
many
34GO:0008168 methyltransferase activity
98
after_TSS
46
yes
TF_ATF6, TF_ARNT,
35GO:0042254 ribosome biogenesis and assembly
74
at_TSS
45
yes
many
36GO:0006260 DNA replication
90
at_TSS
41
yes
many
37GO:0007046 ribosome biogenesis
67
at_TSS
41
yes
many
38GO:0045182 translation regulator activity
90
at_TSS,after_TSS
41
yes
many
39GO:0008135 translation factor activity, nucleic acid binding
86
at_TSS,after_TSS
40
yes
many
40GO:0006259 DNA metabolism
427
after_TSS
40
yes
 
41GO:0006399 tRNA metabolism
86
at_TSS
38
yes
 
42GO:0008026 ATP-dependent helicase activity
86
at_TSS,after_TSS
38
yes
many
43GO:0046903 secretion
123
at_TSS
34
yes
many
44GO:0016817 hydrolase activity, acting on acid anhydrides
450
at_TSS
33
 
TF_E2F,
45GO:0000074 regulation of progression through cell cycle
246
before_TSS
33
yes
 
46GO:0016462 pyrophosphatase activity
447
at_TSS
33
 
TF_E2F,
47GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
450
at_TSS
33
 
TF_E2F,
48GO:0017111 nucleoside-triphosphatase activity
429
at_TSS
32
 
TF_E2F,
49GO:0051246 regulation of protein metabolism
112
at_TSS
31
yes
 
50GO:0016887 ATPase activity
280
at_TSS,after_TSS
31
 
many
51GO:0009451 RNA modification
64
at_TSS
31
yes
TF_NFKB,
52GO:0042623 ATPase activity, coupled
256
at_TSS,after_TSS
29
yes
TF_E2F,
53GO:0045045 secretory pathway
101
at_TSS
29
yes
many
54GO:0016886 ligase activity, forming phosphoric ester bonds
64
at_TSS
29
yes
 
55GO:0006400 tRNA modification
57
at_TSS
26
yes
 
56GO:0043038 amino acid activation
52
at_TSS
25
yes
 
57GO:0004812 tRNA ligase activity
55
at_TSS
25
yes
 
58GO:0008452 RNA ligase activity
55
at_TSS
25
yes
 
59GO:0016875 ligase activity, forming carbon-oxygen bonds
55
at_TSS
25
yes
 
60GO:0043039 tRNA aminoacylation
52
at_TSS
25
yes
 
61GO:0006418 tRNA aminoacylation for protein translation
52
at_TSS
25
yes
 
62GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds
55
at_TSS
25
yes
 
63GO:0003743 translation initiation factor activity
53
at_TSS
24
yes
TF_ELK,
64GO:0006512 ubiquitin cycle
390
at_TSS,before_TSS
24
 
TF_STAT, MIT_003ELK,
65GO:0051301 cell division
134
before_TSS
24
yes
 
66GO:0000910 cytokinesis
125
before_TSS
23
yes
 
67GO:0005386 carrier activity
394
after_TSS
22
 
TF_ER,
68GO:0007264 small GTPase mediated signal transduction
201
at_TSS
22
 
MIT_006SP1,
69GO:0003899 DNA-directed RNA polymerase activity
30
at_TSS
22
yes
 
70GO:0006413 translational initiation
36
at_TSS
21
yes
TF_ATF1, TF_CREB,
71GO:0016072 rRNA metabolism
31
at_TSS
21
yes
many
72GO:0008565 protein transporter activity
120
at_TSS
19
 
MIT_081, TF_ATF6, TF_ARNT,
73GO:0008610 lipid biosynthesis
146
after_TSS
19
 
MIT_012MYOD,
74GO:0030695 GTPase regulator activity
178
before_TSS
19
 
MIT_056PAX4,
75GO:0006364 rRNA processing
29
at_TSS
19
yes
TF_AHR, TF_ETS,
76GO:0007389 pattern specification
128
before_TSS
18
yes
 
77GO:0048193 Golgi vesicle transport
30
at_TSS
16
yes
TF_ELK,
78GO:0007399 nervous system development
301
after_TSS
16
 
TF_AHR,
79GO:0005083 small GTPase regulator activity
110
before_TSS
16
 
MIT_056PAX4,
80GO:0006445 regulation of translation
32
at_TSS
13
yes
 
81GO:0000279 M phase
122
before_TSS
13
 
TF_HNF4,
82GO:0006006 glucose metabolism
71
before_TSS
12
yes
 
83GO:0016052 carbohydrate catabolism
59
before_TSS
11
yes
 
84GO:0044275 cellular carbohydrate catabolism
59
before_TSS
11
yes
 
85GO:0015077 monovalent inorganic cation transporter activity
138
after_TSS
10
 
TF_RORA,
86GO:0006007 glucose catabolism
50
before_TSS
10
yes
 
87GO:0019320 hexose catabolism
50
before_TSS
10
yes
 
88GO:0046164 alcohol catabolism
52
before_TSS
10
yes
 
89GO:0005085 guanyl-nucleotide exchange factor activity
65
before_TSS
10
 
MIT_056PAX4,
90GO:0035295 tube development
61
before_TSS
10
 
TF_CP2,
91GO:0004527 exonuclease activity
39
at_TSS
10
 
TF_HTF,
92GO:0004518 nuclease activity
108
after_TSS
10
 
TF_AHR,
93GO:0046365 monosaccharide catabolism
50
before_TSS
10
yes
 

Pairs of TF_GABP binding sites with other TFBS

No.TFBS
Location
Total GO-s
Main GO annotation
N pairs for
main GO
Total genes
for main GO
1TF_GABP
at_TSS,after_TSS
22
GO:0006996 organelle organization and biogenesis
57
645
2TF_ELK
at_TSS,after_TSS
19
GO:0003723 RNA binding
75
354
3TF_ARNT
at_TSS,after_TSS
16
GO:0008104 protein localization
56
508
4TF_HTF
at_TSS,after_TSS
16
GO:0008104 protein localization
60
508
5MIT_003ELK
at_TSS,after_TSS
15
GO:0006996 organelle organization and biogenesis
50
645
6TF_ATF6
at_TSS,after_TSS
14
GO:0008104 protein localization
64
508
7TF_ATF1
at_TSS,after_TSS
14
GO:0008104 protein localization
71
508
8TF_ETS
at_TSS,after_TSS
12
GO:0003723 RNA binding
59
354
9TF_CREB
at_TSS,after_TSS
12
GO:0008104 protein localization
72
508
10TF_E2F
at_TSS,after_TSS
10
GO:0016462 pyrophosphatase activity
33
447
11TF_AHR
at_TSS,after_TSS
10
GO:0005554 molecular function unknown
78
593
12MIT_006SP1
at_TSS,before_TSS
7
GO:0045184 establishment of protein localization
44
492
13TF_SP1
at_TSS,before_TSS
5
GO:0016772 transferase activity, transferring phosphorus-containing groups
87
787
14MIT_021
at_TSS
4
GO:0007028 cytoplasm organization and biogenesis
13
82
15MIT_081
at_TSS
3
GO:0016192 vesicle-mediated transport
18
228
16TF_NFY
at_TSS
3
GO:0009719 response to endogenous stimulus
18
159
17MIT_056PAX4
before_TSS
3
GO:0030695 GTPase regulator activity
19
178
18MIT_011GABP
at_TSS
3
GO:0007028 cytoplasm organization and biogenesis
13
82
19MIT_055NFAT
at_TSS
2
GO:0006457 protein folding
14
163
20TF_NFKB
at_TSS
2
GO:0009451 RNA modification
10
64
21MIT_012MYOD
after_TSS
2
GO:0009058 biosynthesis
70
878
22TF_STAT
before_TSS
1
GO:0006512 ubiquitin cycle
24
390
23TF_RFX1
after_TSS
1
GO:0016071 mRNA metabolism
18
202
24TF_ZIC
at_TSS
1
GO:0008380 RNA splicing
10
154
25TF_EGR1
at_TSS
1
GO:0051082 unfolded protein binding
12
106
26TF_CP2
before_TSS
1
GO:0035295 tube development
10
61
27TF_ER
after_TSS
1
GO:0005386 carrier activity
22
394
28TF_MYC
after_TSS
1
GO:0016070 RNA metabolism
18
342
29TF_HNF4
before_TSS
1
GO:0000279 M phase
13
122
30TF_RORA
after_TSS
1
GO:0015077 monovalent inorganic cation transporter activity
10
138
31TF_COMP
at_TSS
1
GO:0006260 DNA replication
12
90

Details on Gene Ontology terms for targets of TF_GABP

Total number of genes = 12103
No.In pair
with
Multi-
ple
Conser-
ved
Location
Frequency
in list
U-clusters
in list
Genes with TFBS
in list, %
Genes with TFBS
total, %
Ratio
z
p
FDR
GO annotation
1none
 
 
at_TSS
195
472
41.3
25.9
1.58
7.745
0
0
GO:0009059 macromolecule biosynthesis
2none
 
 
at_TSS
183
421
43.4
25.9
1.67
8.325
0
0
GO:0006412 protein biosynthesis
3none
 
 
at_TSS
156
342
45.6
25.9
1.75
8.396
0
0
GO:0016070 RNA metabolism
4none
 
 
at_TSS
141
354
39.8
25.9
1.53
6.028
0
0
GO:0003723 RNA binding
5none
 
 
after_TSS
126
273
46.1
29.4
1.56
6.121
0
0
GO:0006396 RNA processing
6none
 
 
at_TSS
122
273
44.6
25.9
1.71
7.127
0
0
GO:0006396 RNA processing
7none
 
 
at_TSS
96
183
52.4
25.9
2.01
8.228
0
0
GO:0030529
8none
 
 
after_TSS
95
202
47
29.4
1.59
5.525
0
0
GO:0016071 mRNA metabolism
9none
 
 
at_TSS
91
172
52.9
25.9
2.03
8.108
0
0
GO:0003735 structural constituent of ribosome
10none
 
 
after_TSS
88
189
46.5
29.4
1.58
5.199
0
0
GO:0006397 mRNA processing
11none
 
 
at_TSS
83
202
41
25.9
1.58
4.936
0
0
GO:0016071 mRNA metabolism
12none
 
 
at_TSS
77
189
40.7
25.9
1.56
4.661
0
0.0001
GO:0006397 mRNA processing
13none
 
 
after_TSS
76
154
49.3
29.4
1.67
5.45
0
0
GO:0008380 RNA splicing
14none
 
 
after_TSS
75
149
50.3
29.4
1.7
5.625
0
0
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
15none
 
 
after_TSS
75
149
50.3
29.4
1.7
5.625
0
0
GO:0000398 nuclear mRNA splicing, via spliceosome
16none
 
 
after_TSS
75
149
50.3
29.4
1.7
5.625
0
0
GO:0000375 RNA splicing, via transesterification reactions
17none
yes
 
at_TSS
74
421
17.5
7.1
2.45
8.455
0
0
GO:0006412 protein biosynthesis
18none
 
 
at_TSS
70
136
51.4
25.9
1.98
6.815
0
0
GO:0005840
19none
 
 
at_TSS
68
163
41.7
25.9
1.6
4.61
0
0.0002
GO:0006457 protein folding
20none
 
 
at_TSS
65
156
41.6
25.9
1.6
4.494
0
0.0003
GO:0006974 response to DNA damage stimulus
21none
 
 
at_TSS
65
128
50.7
25.9
1.95
6.43
0
0
GO:0043037 translation
22none
 
 
at_TSS
65
159
40.8
25.9
1.57
4.31
0
0.0008
GO:0009719 response to endogenous stimulus
23none
 
 
at_TSS
63
154
40.9
25.9
1.57
4.249
0
0.0007
GO:0008380 RNA splicing
24none
 
 
at_TSS
60
149
40.2
25.9
1.54
4
0
0.0025
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
25none
 
 
at_TSS
60
149
40.2
25.9
1.54
4
0
0.0025
GO:0000398 nuclear mRNA splicing, via spliceosome
26none
 
 
at_TSS
60
149
40.2
25.9
1.54
4
0
0.0025
GO:0000375 RNA splicing, via transesterification reactions
27none
 
 
at_TSS
59
133
44.3
25.9
1.7
4.858
0
0
GO:0006281 DNA repair
28none
 
yes
before_TSS
55
443
12.4
7.6
1.63
3.894
0
0.012
GO:0007049 cell cycle
29none
 
yes
at_TSS
52
228
22.8
14.8
1.53
3.429
0.0006
0.0554
GO:0016192 vesicle-mediated transport
30none
yes
 
before_TSS
49
354
13.8
6.6
2.07
5.491
0
0
GO:0003723 RNA binding
31none
 
 
at_TSS
49
82
59.7
25.9
2.29
6.996
0
0
GO:0007028 cytoplasm organization and biogenesis
32none
 
 
at_TSS
48
106
45.2
25.9
1.74
4.55
0
0.0003
GO:0051082 unfolded protein binding
33none
yes
 
after_TSS
48
354
13.5
5.8
2.32
6.305
0
0
GO:0003723 RNA binding
34none
 
 
at_TSS
48
91
52.7
25.9
2.02
5.843
0
0
GO:0016779 nucleotidyltransferase activity
35none
 
 
after_TSS
46
98
46.9
29.4
1.59
3.812
0.0001
0.01
GO:0008168 methyltransferase activity
36none
 
 
after_TSS
46
101
45.5
29.4
1.54
3.561
0.0003
0.027
GO:0016741 transferase activity, transferring one-carbon groups
37none
 
 
at_TSS
46
108
42.5
25.9
1.63
3.952
0
0.0056
GO:0004386 helicase activity
38none
 
 
at_TSS
45
74
60.8
25.9
2.34
6.851
0
0
GO:0042254 ribosome biogenesis and assembly
39none
yes
 
after_TSS
44
342
12.8
5.8
2.2
5.639
0
0
GO:0016070 RNA metabolism
40none
yes
 
at_TSS
42
183
22.9
7.1
3.21
8.362
0
0
GO:0030529
41none
 
 
at_TSS
41
67
61.1
25.9
2.35
6.589
0
0
GO:0007046 ribosome biogenesis
42none
 
 
after_TSS
41
90
45.5
29.4
1.54
3.363
0.0007
0.0235
GO:0045182 translation regulator activity
43none
 
 
at_TSS
41
90
45.5
25.9
1.75
4.249
0
0.0009
GO:0006260 DNA replication
44none
 
 
at_TSS
41
90
45.5
25.9
1.75
4.249
0
0.0005
GO:0045182 translation regulator activity
45none
yes
 
after_TSS
40
427
9.3
5.8
1.6
3.182
0.0014
0.0267
GO:0006259 DNA metabolism
46none
 
 
after_TSS
40
86
46.5
29.4
1.57
3.482
0.0004
0.0182
GO:0008135 translation factor activity, nucleic acid binding
47none
 
 
at_TSS
39
86
45.3
25.9
1.74
4.109
0
0.001
GO:0008135 translation factor activity, nucleic acid binding
48none
 
 
at_TSS
38
86
44.1
25.9
1.7
3.862
0.0001
0.0051
GO:0006399 tRNA metabolism
49none
 
 
at_TSS
38
86
44.1
25.9
1.7
3.862
0.0001
0.0102
GO:0008026 ATP-dependent helicase activity
50none
yes
 
before_TSS
37
342
10.8
6.6
1.62
3.121
0.0018
0.0659
GO:0016070 RNA metabolism
51none
 
 
after_TSS
34
54
62.9
29.4
2.13
5.413
0
0
GO:0005681
52none
 
yes
at_TSS
34
123
27.6
14.8
1.86
4.025
0
0.0104
GO:0046903 secretion
53none
 
yes
before_TSS
33
246
13.4
7.6
1.76
3.475
0.0005
0.0311
GO:0000074 regulation of progression through cell cycle
54none
yes
yes
at_TSS
33
613
5.3
2.9
1.84
3.707
0.0002
0.0255
GO:0005622
55none
yes
yes
at_TSS
33
492
6.7
2.9
2.29
5.083
0
0.0001
GO:0045184 establishment of protein localization
56none
yes
yes
at_TSS
33
508
6.4
2.9
2.22
4.88
0
0.0003
GO:0008104 protein localization
57none
yes
yes
at_TSS
32
476
6.7
2.9
2.29
5.016
0
0
GO:0015031 protein transport
58none
yes
 
after_TSS
32
202
15.8
5.8
2.71
6.129
0
0
GO:0016071 mRNA metabolism
59none
yes
yes
at_TSS
32
472
6.7
2.9
2.31
5.069
0
0
GO:0009059 macromolecule biosynthesis
60none
 
 
at_TSS
31
64
48.4
25.9
1.86
4.106
0
0.0024
GO:0009451 RNA modification
61none
yes
 
at_TSS
31
136
22.7
7.1
3.18
7.123
0
0
GO:0005840
62none
 
yes
at_TSS
31
112
27.6
14.8
1.86
3.85
0.0001
0.0432
GO:0051246 regulation of protein metabolism
63none
yes
 
after_TSS
30
189
15.8
5.8
2.72
5.944
0
0
GO:0006397 mRNA processing
64none
yes
 
after_TSS
29
149
19.4
5.8
3.34
7.151
0
0
GO:0000375 RNA splicing, via transesterification reactions
65none
yes
 
after_TSS
29
149
19.4
5.8
3.34
7.151
0
0
GO:0000398 nuclear mRNA splicing, via spliceosome
66none
 
 
at_TSS
29
64
45.3
25.9
1.74
3.534
0.0004
0.0299
GO:0016886 ligase activity, forming phosphoric ester bonds
67none
yes
 
after_TSS
29
149
19.4
5.8
3.34
7.151
0
0
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
68none
 
yes
at_TSS
29
101
28.7
14.8
1.93
3.948
0
0.0096
GO:0045045 secretory pathway
69none
yes
 
after_TSS
29
154
18.8
5.8
3.23
6.935
0
0
GO:0008380 RNA splicing
70none
 
 
at_TSS
29
58
50
25.9
1.92
4.18
0
0.0035
GO:0005730
71none
yes
 
after_TSS
29
256
11.3
5.8
1.94
3.799
0.0001
0.0531
GO:0042623 ATPase activity, coupled
72none
yes
yes
at_TSS
28
478
5.8
2.9
2
3.882
0.0001
0.0126
GO:0046907 intracellular transport
73none
 
 
at_TSS
28
54
51.8
25.9
1.99
4.343
0
0.0017
GO:0005681
74none
yes
 
at_TSS
27
163
16.5
7.1
2.31
4.698
0
0.0002
GO:0006457 protein folding
75none
 
 
at_TSS
26
57
45.6
25.9
1.75
3.386
0.0007
0.037
GO:0006400 tRNA modification
76none
 
 
at_TSS
25
53
47.1
25.9
1.81
3.524
0.0004
0.0388
GO:0019866
77none
 
 
at_TSS
25
55
45.4
25.9
1.74
3.299
0.0009
0.0591
GO:0016875 ligase activity, forming carbon-oxygen bonds
78none
 
 
at_TSS
25
52
48
25.9
1.85
3.64
0.0002
0.0166
GO:0043038 amino acid activation
79none
 
 
at_TSS
25
52
48
25.9
1.85
3.64
0.0002
0.0166
GO:0006418 tRNA aminoacylation for protein translation
80none
yes
 
at_TSS
25
74
33.7
7.1
4.72
8.921
0
0
GO:0042254 ribosome biogenesis and assembly
81none
 
 
at_TSS
25
55
45.4
25.9
1.74
3.299
0.0009
0.0591
GO:0004812 tRNA ligase activity
82none
yes
yes
at_TSS
25
342
7.3
2.9
2.49
4.881
0
0.0003
GO:0016070 RNA metabolism
83none
yes
 
at_TSS
25
82
30.4
7.1
4.26
8.232
0
0
GO:0007028 cytoplasm organization and biogenesis
84none
 
 
at_TSS
25
55
45.4
25.9
1.74
3.299
0.0009
0.0591
GO:0008452 RNA ligase activity
85none
 
 
at_TSS
25
52
48
25.9
1.85
3.64
0.0002
0.0166
GO:0043039 tRNA aminoacylation
86none
 
 
at_TSS
25
55
45.4
25.9
1.74
3.299
0.0009
0.0591
GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds
87none
yes
 
at_TSS
24
67
35.8
7.1
5.01
9.135
0
0
GO:0007046 ribosome biogenesis
88none
 
 
at_TSS
24
53
45.2
25.9
1.74
3.21
0.0013
0.0323
GO:0003743 translation initiation factor activity
89none
 
yes
before_TSS
24
134
17.9
7.6
2.35
4.527
0
0.0021
GO:0051301 cell division
90none
yes
 
before_TSS
23
189
12.1
6.6
1.82
3.055
0.0022
0.0823
GO:0006397 mRNA processing
91none
yes
yes
at_TSS
23
350
6.5
2.9
2.24
4.108
0
0.0048
GO:0006886 intracellular protein transport
92none
 
yes
before_TSS
23
125
18.4
7.6
2.42
4.579
0
0.0017
GO:0000910 cytokinesis
93none
yes
 
at_TSS
22
106
20.7
7.1
2.9
5.462
0
0
GO:0051082 unfolded protein binding
94none
yes
 
after_TSS
22
156
14.1
5.8
2.42
4.442
0
0.0016
GO:0006974 response to DNA damage stimulus
95none
yes
 
after_TSS
22
159
13.8
5.8
2.37
4.341
0
0.0025
GO:0009719 response to endogenous stimulus
96none
 
 
at_TSS
22
30
73.3
25.9
2.82
5.92
0
0
GO:0003899 DNA-directed RNA polymerase activity
97none
 
 
at_TSS
21
31
67.7
25.9
2.6
5.307
0
0
GO:0016072 rRNA metabolism
98none
 
 
at_TSS
21
36
58.3
25.9
2.24
4.432
0
0.0011
GO:0006413 translational initiation
99none
yes
yes
at_TSS
20
228
8.7
2.9
2.99
5.289
0
0
GO:0016192 vesicle-mediated transport
100none
yes
 
after_TSS
20
133
15
5.8
2.58
4.561
0
0.0009
GO:0006281 DNA repair
101none
yes
yes
at_TSS
20
273
7.3
2.9
2.5
4.364
0
0.0046
GO:0006396 RNA processing
102none
 
 
at_TSS
19
29
65.5
25.9
2.52
4.859
0
0
GO:0006364 rRNA processing
103none
yes
 
before_TSS
19
149
12.7
6.6
1.91
2.995
0.0027
0.0772
GO:0000398 nuclear mRNA splicing, via spliceosome
104none
yes
 
before_TSS
19
134
14.1
6.6
2.12
3.504
0.0004
0.0419
GO:0051301 cell division
105none
yes
 
before_TSS
19
149
12.7
6.6
1.91
2.995
0.0027
0.0772
GO:0000375 RNA splicing, via transesterification reactions
106none
yes
 
before_TSS
19
149
12.7
6.6
1.91
2.995
0.0027
0.0772
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
107none
 
yes
before_TSS
18
128
14
7.6
1.84
2.772
0.0055
0.0323
GO:0007389 pattern specification
108none
yes
 
after_TSS
18
108
16.6
5.8
2.86
4.831
0
0.0004
GO:0004386 helicase activity
109none
yes
 
before_TSS
18
125
14.4
6.6
2.15
3.483
0.0004
0.0453
GO:0000910 cytokinesis
110none
 
yes
before_TSS
18
106
16.9
7.6
2.23
3.659
0.0002
0.0926
GO:0051082 unfolded protein binding
111none
yes
 
at_TSS
17
90
18.8
7.1
2.64
4.34
0
0.0004
GO:0045182 translation regulator activity
112none
yes
 
after_TSS
17
128
13.2
5.8
2.28
3.62
0.0002
0.0215
GO:0043037 translation
113none
yes
 
at_TSS
17
86
19.7
7.1
2.76
4.559
0
0.0001
GO:0008135 translation factor activity, nucleic acid binding
114none
yes
yes
at_TSS
17
172
9.8
2.9
3.37
5.454
0
0
GO:0003735 structural constituent of ribosome
115none
 
 
at_TSS
16
28
57.1
25.9
2.19
3.763
0.0001
0.0204
GO:0000139
116none
 
 
at_TSS
16
30
53.3
25.9
2.05
3.419
0.0006
0.0575
GO:0048193 Golgi vesicle transport
117none
yes
 
after_TSS
15
86
17.4
5.8
2.99
4.615
0
0.0007
GO:0008026 ATP-dependent helicase activity
118none
 
 
at_TSS
14
23
60.8
25.9
2.34
3.818
0.0001
0.0123
GO:0005830
119none
yes
 
after_TSS
14
90
15.5
5.8
2.67
3.955
0
0.0056
GO:0045182 translation regulator activity
120none
yes
 
after_TSS
13
86
15.1
5.8
2.59
3.691
0.0002
0.0116
GO:0008135 translation factor activity, nucleic acid binding
121none
 
yes
at_TSS
13
32
40.6
14.8
2.74
4.115
0
0.0141
GO:0006445 regulation of translation
122none
yes
yes
at_TSS
13
123
10.5
2.9
3.61
5.056
0
0.0001
GO:0046903 secretion
123none
yes
 
before_TSS
12
71
16.9
6.6
2.53
3.466
0.0005
0.0966
GO:0006006 glucose metabolism
124none
yes
 
at_TSS
11
30
36.6
7.1
5.13
6.283
0
0
GO:0003899 DNA-directed RNA polymerase activity
125none
yes
 
at_TSS
11
31
35.4
7.1
4.96
6.132
0
0
GO:0016072 rRNA metabolism
126none
yes
yes
at_TSS
11
128
8.5
2.9
2.93
3.826
0.0001
0.0476
GO:0043037 translation
127none
yes
 
at_TSS
11
53
20.7
7.1
2.9
3.853
0.0001
0.0071
GO:0003743 translation initiation factor activity
128none
yes
 
before_TSS
11
59
18.6
6.6
2.79
3.696
0.0002
0.0801
GO:0044275 cellular carbohydrate catabolism
129none
yes
 
before_TSS
11
59
18.6
6.6
2.79
3.696
0.0002
0.0801
GO:0016052 carbohydrate catabolism
130none
yes
yes
at_TSS
11
101
10.8
2.9
3.72
4.77
0
0.0006
GO:0045045 secretory pathway
131none
yes
 
at_TSS
10
29
34.4
7.1
4.82
5.721
0
0
GO:0006364 rRNA processing
132none
yes
 
before_TSS
10
50
20
6.6
2.99
3.786
0.0001
0.056
GO:0019320 hexose catabolism
133none
yes
 
before_TSS
10
50
20
6.6
2.99
3.786
0.0001
0.056
GO:0046365 monosaccharide catabolism
134none
yes
 
before_TSS
10
52
19.2
6.6
2.88
3.639
0.0002
0.05
GO:0046164 alcohol catabolism
135none
 
yes
at_TSS
10
23
43.4
14.8
2.93
3.873
0.0001
0.0196
GO:0005802
136none
yes
 
before_TSS
10
50
20
6.6
2.99
3.786
0.0001
0.056
GO:0006007 glucose catabolism
137none
yes
 
before_TSS
10
54
18.5
6.6
2.77
3.498
0.0004
0.0428
GO:0005681
138MIT_003ELK
 
 
at_TSS
50
645
7.7
4.4
1.72
4.103
0
0.0345
GO:0006996 organelle organization and biogenesis
139MIT_003ELK
yes
 
at_TSS
31
472
6.5
2.6
2.47
5.4
0
0.0014
GO:0009059 macromolecule biosynthesis
140MIT_003ELK
yes
 
at_TSS
25
354
7
2.6
2.66
5.24
0
0.0002
GO:0003723 RNA binding
141MIT_003ELK
yes
 
at_TSS
23
342
6.7
2.6
2.53
4.755
0
0.0057
GO:0016070 RNA metabolism
142MIT_003ELK
yes
 
at_TSS
23
390
5.8
2.6
2.22
4.054
0
0.0805
GO:0006512 ubiquitin cycle
143MIT_003ELK
 
 
at_TSS
20
74
27
4.4
6.01
9.383
0
0
GO:0042254 ribosome biogenesis and assembly
144MIT_003ELK
 
 
at_TSS
20
82
24.3
4.4
5.42
8.724
0
0
GO:0007028 cytoplasm organization and biogenesis
145MIT_003ELK
 
 
at_TSS
20
67
29.8
4.4
6.64
10.044
0
0
GO:0007046 ribosome biogenesis
146MIT_003ELK
yes
 
at_TSS
20
288
6.9
2.6
2.61
4.587
0
0.0215
GO:0005794
147MIT_003ELK
yes
 
at_TSS
17
172
9.8
2.6
3.72
5.944
0
0
GO:0003735 structural constituent of ribosome
148MIT_003ELK
 
 
at_TSS
15
90
16.6
4.4
3.7
5.593
0
0
GO:0045182 translation regulator activity
149MIT_003ELK
 
 
at_TSS
14
86
16.2
4.4
3.62
5.293
0
0.0003
GO:0008135 translation factor activity, nucleic acid binding
150MIT_003ELK
yes
 
at_TSS
12
128
9.3
2.6
3.53
4.758
0
0.007
GO:0043037 translation
151MIT_003ELK
 
 
after_TSS
10
149
6.7
1.3
5.01
5.742
0
0
GO:0000398 nuclear mRNA splicing, via spliceosome
152MIT_003ELK
 
 
after_TSS
10
149
6.7
1.3
5.01
5.742
0
0
GO:0000375 RNA splicing, via transesterification reactions
153MIT_003ELK
 
 
at_TSS
10
53
18.8
4.4
4.19
5.061
0
0.0045
GO:0019866
154MIT_003ELK
 
 
after_TSS
10
149
6.7
1.3
5.01
5.742
0
0
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
155MIT_006SP1
 
yes
at_TSS
44
492
8.9
4.2
2.1
5.287
0
0.0004
GO:0045184 establishment of protein localization
156MIT_006SP1
 
yes
at_TSS
43
476
9
4.2
2.13
5.297
0
0.0005
GO:0015031 protein transport
157MIT_006SP1
 
 
before_TSS
39
354
11
4.9
2.24
5.388
0
0.001
GO:0003723 RNA binding
158MIT_006SP1
 
yes
at_TSS
31
350
8.8
4.2
2.08
4.351
0
0.0418
GO:0006886 intracellular protein transport
159MIT_006SP1
 
yes
at_TSS
28
288
9.7
4.2
2.29
4.674
0
0.0098
GO:0005794
160MIT_006SP1
 
 
at_TSS
27
106
25.4
11.4
2.22
4.56
0
0.0105
GO:0051082 unfolded protein binding
161MIT_006SP1
 
yes
at_TSS
22
201
10.9
4.2
2.58
4.758
0
0.0844
GO:0007264 small GTPase mediated signal transduction
162MIT_006SP1
yes
 
at_TSS
18
91
19.7
5.3
3.66
6.096
0
0
GO:0016779 nucleotidyltransferase activity
163MIT_011GABP
 
 
at_TSS
13
74
17.5
2.8
6.18
7.645
0
0
GO:0042254 ribosome biogenesis and assembly
164MIT_011GABP
 
 
at_TSS
13
67
19.4
2.8
6.82
8.179
0
0
GO:0007046 ribosome biogenesis
165MIT_011GABP
 
 
at_TSS
13
82
15.8
2.8
5.57
7.114
0
0
GO:0007028 cytoplasm organization and biogenesis
166MIT_012MYOD
 
 
after_TSS
70
878
7.9
4.7
1.68
4.723
0
0.0251
GO:0009058 biosynthesis
167MIT_012MYOD
 
 
after_TSS
19
146
13
4.7
2.75
4.756
0
0.0426
GO:0008610 lipid biosynthesis
168MIT_021
 
 
at_TSS
13
82
15.8
2
7.73
8.853
0
0
GO:0007028 cytoplasm organization and biogenesis
169MIT_021
 
 
at_TSS
12
67
17.9
2
8.74
9.189
0
0
GO:0007046 ribosome biogenesis
170MIT_021
 
 
at_TSS
12
74
16.2
2
7.91
8.628
0
0
GO:0042254 ribosome biogenesis and assembly
171MIT_021
 
 
at_TSS
11
154
7.1
2
3.48
4.49
0
0.0439
GO:0008380 RNA splicing
172MIT_055NFAT
 
 
at_TSS
14
163
8.5
1.8
4.68
6.47
0
0
GO:0006457 protein folding
173MIT_055NFAT
 
 
at_TSS
10
106
9.4
1.8
5.14
5.856
0
0.0001
GO:0051082 unfolded protein binding
174MIT_056PAX4
 
 
before_TSS
19
178
10.6
3.6
2.94
5.077
0
0.0165
GO:0030695 GTPase regulator activity
175MIT_056PAX4
 
 
before_TSS
16
110
14.5
3.6
4.01
6.163
0
0
GO:0005083 small GTPase regulator activity
176MIT_056PAX4
 
 
before_TSS
10
65
15.3
3.6
4.25
5.092
0
0.0153
GO:0005085 guanyl-nucleotide exchange factor activity
177MIT_081
 
 
at_TSS
18
228
7.8
2.6
2.95
4.942
0
0.0334
GO:0016192 vesicle-mediated transport
178MIT_081
 
 
at_TSS
11
120
9.1
2.6
3.43
4.438
0
0.0327
GO:0008565 protein transporter activity
179MIT_081
 
 
at_TSS
10
101
9.9
2.6
3.7
4.528
0
0.0321
GO:0045045 secretory pathway
180TF_AHR
 
 
at_TSS
78
593
13.1
8.1
1.62
4.608
0
0.0146
GO:0005554 molecular function unknown
181TF_AHR
 
 
at_TSS
75
547
13.7
8.1
1.68
4.906
0
0.0133
GO:0005739
182TF_AHR
yes
 
at_TSS
35
342
10.2
2.9
3.41
7.956
0
0
GO:0016070 RNA metabolism
183TF_AHR
yes
 
at_TSS
27
273
9.8
2.9
3.29
6.751
0
0
GO:0006396 RNA processing
184TF_AHR
yes
 
at_TSS
26
354
7.3
2.9
2.44
4.864
0
0.0012
GO:0003723 RNA binding
185TF_AHR
 
 
at_TSS
22
106
20.7
8.1
2.55
4.787
0
0.0043
GO:0051082 unfolded protein binding
186TF_AHR
 
 
at_TSS
17
58
29.3
8.1
3.61
5.926
0
0
GO:0005730
187TF_AHR
 
yes
after_TSS
16
301
5.3
1.7
2.96
4.663
0
0.0122
GO:0007399 nervous system development
188TF_AHR
yes
 
after_TSS
16
273
5.8
2
2.83
4.459
0
0.0254
GO:0006396 RNA processing
189TF_AHR
 
 
at_TSS
13
31
41.9
8.1
5.16
6.905
0
0
GO:0016072 rRNA metabolism
190TF_AHR
yes
 
at_TSS
13
106
12.2
2.9
4.08
5.616
0
0.0001
GO:0051082 unfolded protein binding
191TF_AHR
yes
 
at_TSS
12
91
13.1
2.9
4.39
5.718
0
0
GO:0016779 nucleotidyltransferase activity
192TF_AHR
 
 
at_TSS
12
29
41.3
8.1
5.09
6.568
0
0
GO:0006364 rRNA processing
193TF_AHR
yes
 
at_TSS
10
58
17.2
2.9
5.74
6.374
0
0
GO:0005730
194TF_AHR
yes
 
after_TSS
10
108
9.2
2
4.48
5.279
0
0.0056
GO:0004518 nuclease activity
195TF_ARNT
 
 
at_TSS
56
508
11
5.5
1.98
5.489
0
0.0001
GO:0008104 protein localization
196TF_ARNT
 
 
at_TSS
55
492
11.1
5.5
2.01
5.551
0
0.0001
GO:0045184 establishment of protein localization
197TF_ARNT
 
 
at_TSS
54
478
11.2
5.5
2.03
5.584
0
0
GO:0046907 intracellular transport
198TF_ARNT
 
 
at_TSS
54
476
11.3
5.5
2.04
5.618
0
0
GO:0015031 protein transport
199TF_ARNT
 
 
at_TSS
43
350
12.2
5.5
2.2
5.571
0
0.0001
GO:0006886 intracellular protein transport
200TF_ARNT
 
 
after_TSS
41
354
11.5
5.1
2.22
5.492
0
0.0004
GO:0003723 RNA binding
201TF_ARNT
 
 
after_TSS
37
273
13.5
5.1
2.6
6.291
0
0
GO:0006396 RNA processing
202TF_ARNT
 
 
after_TSS
31
280
11
5.1
2.13
4.48
0
0.0403
GO:0016887 ATPase activity
203TF_ARNT
 
 
after_TSS
21
108
19.4
5.1
3.74
6.7
0
0
GO:0004386 helicase activity
204TF_ARNT
 
 
at_TSS
19
123
15.4
5.5
2.77
4.809
0
0.0081
GO:0046903 secretion
205TF_ARNT
 
 
after_TSS
18
86
20.9
5.1
4.02
6.596
0
0
GO:0008026 ATP-dependent helicase activity
206TF_ARNT
 
 
at_TSS
18
120
15
5.5
2.69
4.534
0
0.025
GO:0008565 protein transporter activity
207TF_ARNT
 
 
after_TSS
16
98
16.3
5.1
3.14
4.983
0
0.009
GO:0008168 methyltransferase activity
208TF_ARNT
 
 
after_TSS
16
101
15.8
5.1
3.04
4.839
0
0.0187
GO:0016741 transferase activity, transferring one-carbon groups
209TF_ARNT
 
 
at_TSS
16
101
15.8
5.5
2.84
4.527
0
0.0287
GO:0045045 secretory pathway
210TF_ARNT
 
yes
at_TSS
13
228
5.7
1.6
3.5
4.907
0
0.0199
GO:0016192 vesicle-mediated transport
211TF_ARNT
 
 
after_TSS
11
58
18.9
5.1
3.64
4.735
0
0.0946
GO:0005730
212TF_ATF1
 
 
at_TSS
71
508
13.9
7.5
1.85
5.638
0
0
GO:0008104 protein localization
213TF_ATF1
 
 
at_TSS
68
492
13.8
7.5
1.83
5.412
0
0.0002
GO:0045184 establishment of protein localization
214TF_ATF1
 
 
at_TSS
66
476
13.8
7.5
1.84
5.357
0
0.0002
GO:0015031 protein transport
215TF_ATF1
 
 
at_TSS
63
354
17.7
7.5
2.36
7.442
0
0
GO:0003723 RNA binding
216TF_ATF1
 
 
at_TSS
62
478
12.9
7.5
1.72
4.612
0
0.0071
GO:0046907 intracellular transport
217TF_ATF1
 
 
at_TSS
47
350
13.4
7.5
1.78
4.254
0
0.0266
GO:0006886 intracellular protein transport
218TF_ATF1
yes
 
at_TSS
35
613
5.7
2.7
2.05
4.536
0
0.0165
GO:0005622
219TF_ATF1
yes
 
at_TSS
26
342
7.6
2.7
2.73
5.51
0
0.0001
GO:0016070 RNA metabolism
220TF_ATF1
 
 
at_TSS
24
123
19.5
7.5
2.59
5.069
0
0.0024
GO:0046903 secretion
221TF_ATF1
 
 
at_TSS
20
101
19.8
7.5
2.63
4.7
0
0.016
GO:0045045 secretory pathway
222TF_ATF1
yes
 
at_TSS
20
273
7.3
2.7
2.63
4.628
0
0.0132
GO:0006396 RNA processing
223TF_ATF1
 
 
after_TSS
19
108
17.5
5.8
2.98
5.18
0
0.001
GO:0004386 helicase activity
224TF_ATF1
yes
 
at_TSS
16
172
9.3
2.7
3.35
5.246
0
0.0008
GO:0003735 structural constituent of ribosome
225TF_ATF1
 
 
after_TSS
15
86
17.4
5.8
2.95
4.559
0
0.0277
GO:0008026 ATP-dependent helicase activity
226TF_ATF1
 
 
at_TSS
15
54
27.7
7.5
3.69
5.658
0
0.0003
GO:0005681
227TF_ATF1
 
 
at_TSS
10
36
27.7
7.5
3.69
4.616
0
0.0281
GO:0006413 translational initiation
228TF_ATF6
 
 
at_TSS
64
508
12.5
5.4
2.29
7.205
0
0
GO:0008104 protein localization
229TF_ATF6
 
 
at_TSS
61
492
12.3
5.4
2.26
6.887
0
0
GO:0045184 establishment of protein localization
230TF_ATF6
 
 
at_TSS
60
476
12.6
5.4
2.3
6.971
0
0
GO:0015031 protein transport
231TF_ATF6
 
 
at_TSS
59
478
12.3
5.4
2.25
6.73
0
0
GO:0046907 intracellular transport
232TF_ATF6
 
 
at_TSS
49
350
14
5.4
2.55
7.109
0
0
GO:0006886 intracellular protein transport
233TF_ATF6
 
 
after_TSS
28
280
10
4.3
2.3
4.694
0
0.0289
GO:0016887 ATPase activity
234TF_ATF6
 
 
at_TSS
21
123
17
5.4
3.11
5.68
0
0.0001
GO:0046903 secretion
235TF_ATF6
 
 
at_TSS
19
120
15.8
5.4
2.89
5.009
0
0.0039
GO:0008565 protein transporter activity
236TF_ATF6
 
 
after_TSS
18
108
16.6
4.3
3.83
6.307
0
0
GO:0004386 helicase activity
237TF_ATF6
 
 
at_TSS
18
101
17.8
5.4
3.25
5.474
0
0.0004
GO:0045045 secretory pathway
238TF_ATF6
 
 
after_TSS
16
86
18.6
4.3
4.28
6.508
0
0
GO:0008026 ATP-dependent helicase activity
239TF_ATF6
 
 
after_TSS
14
101
13.8
4.3
3.18
4.709
0
0.0268
GO:0016741 transferase activity, transferring one-carbon groups
240TF_ATF6
 
 
after_TSS
14
98
14.2
4.3
3.28
4.845
0
0.0136
GO:0008168 methyltransferase activity
241TF_ATF6
 
yes
at_TSS
13
228
5.7
1.6
3.39
4.777
0
0.0256
GO:0016192 vesicle-mediated transport
242TF_COMP
 
 
at_TSS
12
90
13.3
2.3
5.74
6.962
0
0
GO:0006260 DNA replication
243TF_CP2
 
 
before_TSS
10
61
16.3
3.4
4.72
5.528
0
0.0001
GO:0035295 tube development
244TF_CREB
 
 
at_TSS
72
508
14.1
7
2
6.388
0
0
GO:00081