CisView Mouse (mm6, March 2005)

Main Gene Ontology terms for targets of TF_HMX

No.GO annotation
Total
genes
with GO
Location
Max no. of
genes with
TF_HMX
TF_HMX alone
In pair
with
1GO:0019222 regulation of metabolism
1541
at_TSS
78
yes
 
2GO:0031323 regulation of cellular metabolism
1510
at_TSS
77
yes
 
3GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
1420
at_TSS
74
yes
 
4GO:0006350 transcription
1461
at_TSS
74
yes
 
5GO:0045449 regulation of transcription
1410
at_TSS
74
yes
 
6GO:0006355 regulation of transcription, DNA-dependent
1362
at_TSS
71
yes
 
7GO:0006351 transcription, DNA-dependent
1383
at_TSS
71
yes
 
8GO:0009887 organ morphogenesis
674
at_TSS,after_TSS
57
yes
 
9GO:0030528 transcription regulator activity
941
at_TSS
54
yes
 
10GO:0003700 transcription factor activity
719
at_TSS
43
yes
 
11GO:0009653 morphogenesis
811
at_TSS
42
yes
 
12GO:0006954 inflammatory response
101
before_TSS,after_TSS
42
yes
MIT_012MYOD,
13GO:0004857 enzyme inhibitor activity
155
after_TSS
37
yes
 
14GO:0005529 sugar binding
144
after_TSS
37
yes
 
15GO:0030154 cell differentiation
538
before_TSS
34
yes
 
16GO:0006913 nucleocytoplasmic transport
70
before_TSS
30
yes
TF_STAT,
17GO:0007399 nervous system development
301
at_TSS,before_TSS,after_TSS
27
yes
 
18GO:0006955 immune response
379
after_TSS
21
 
MIT_012MYOD,
19GO:0006812 cation transport
401
before_TSS
21
 
TF_CP2,
20GO:0003735 structural constituent of ribosome
172
before_TSS
19
 
TF_STAT,
21GO:0016835 carbon-oxygen lyase activity
52
after_TSS
18
yes
 
22GO:0015267 channel or pore class transporter activity
307
before_TSS
18
 
TF_CP2,
23GO:0015268 alpha-type channel activity
295
before_TSS
18
 
TF_CP2,
24GO:0005216 ion channel activity
269
before_TSS
17
 
TF_CP2,
25GO:0030001 metal ion transport
288
before_TSS
17
 
TF_CP2,
26GO:0015672 monovalent inorganic cation transport
259
before_TSS
17
 
TF_CP2,
27GO:0006399 tRNA metabolism
86
at_TSS
16
yes
 
28GO:0006366 transcription from RNA polymerase II promoter
231
at_TSS
16
yes
 
29GO:0016836 hydro-lyase activity
44
after_TSS
16
yes
 
30GO:0005261 cation channel activity
198
before_TSS,after_TSS
15
 
MIT_101, TF_CP2,
31GO:0009790 embryonic development
170
before_TSS
15
yes
 
32GO:0006897 endocytosis
116
after_TSS
15
yes
 
33GO:0009611 response to wounding
180
after_TSS
14
 
MIT_012MYOD,
34GO:0042087 cell-mediated immune response
21
before_TSS
13
yes
 
35GO:0045941 positive regulation of transcription
103
after_TSS
13
yes
 
36GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
104
after_TSS
13
yes
 
37GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
208
before_TSS
13
 
TF_IRF,
38GO:0042088 T-helper 1 type immune response
20
before_TSS
13
yes
 
39GO:0006325 establishment and/or maintenance of chromatin architecture
179
before_TSS
12
 
TF_IRF,
40GO:0006323 DNA packaging
188
before_TSS
12
 
TF_IRF,
41GO:0006909 phagocytosis
24
after_TSS
12
yes
 
42GO:0005244 voltage-gated ion channel activity
134
before_TSS
11
 
TF_CP2, MIT_056PAX4,
43GO:0006813 potassium ion transport
135
before_TSS
11
 
TF_CP2,
44GO:0006461 protein complex assembly
123
before_TSS
10
 
TF_IRF,
45GO:0005267 potassium channel activity
112
before_TSS
10
 
TF_CP2,
46GO:0007276 gametogenesis
119
before_TSS
10
 
TF_CLOX,

Pairs of TF_HMX binding sites with other TFBS

No.TFBS
Location
Total GO-s
Main GO annotation
N pairs for
main GO
Total genes
for main GO
1TF_CP2
before_TSS
10
GO:0006812 cation transport
21
401
2TF_IRF
before_TSS
4
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
13
208
3MIT_012MYOD
after_TSS
3
GO:0006955 immune response
21
379
4TF_STAT
before_TSS
2
GO:0003735 structural constituent of ribosome
19
172
5TF_CLOX
before_TSS
1
GO:0007276 gametogenesis
10
119
6MIT_056PAX4
before_TSS
1
GO:0005244 voltage-gated ion channel activity
10
134
7MIT_101
after_TSS
1
GO:0005261 cation channel activity
11
198

Details on Gene Ontology terms for targets of TF_HMX

Total number of genes = 12103
No.In pair
with
Multi-
ple
Conser-
ved
Location
Frequency
in list
U-clusters
in list
Genes with TFBS
in list, %
Genes with TFBS
total, %
Ratio
z
p
FDR
GO annotation
1none
 
yes
at_TSS
78
1541
5
3
1.68
5.053
0
0
GO:0019222 regulation of metabolism
2none
 
yes
at_TSS
77
1510
5
3
1.69
5.086
0
0
GO:0031323 regulation of cellular metabolism
3none
 
yes
at_TSS
74
1410
5.2
3
1.74
5.24
0
0
GO:0045449 regulation of transcription
4none
 
yes
at_TSS
74
1461
5
3
1.68
4.91
0
0
GO:0006350 transcription
5none
 
yes
at_TSS
74
1420
5.2
3
1.73
5.175
0
0
GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
6none
 
yes
at_TSS
71
1362
5.2
3
1.73
5.058
0
0
GO:0006355 regulation of transcription, DNA-dependent
7none
 
yes
at_TSS
71
1383
5.1
3
1.7
4.919
0
0
GO:0006351 transcription, DNA-dependent
8none
 
yes
after_TSS
57
674
8.4
5.4
1.53
3.473
0.0005
0.0055
GO:0009887 organ morphogenesis
9none
 
yes
at_TSS
54
941
5.7
3
1.9
5.107
0
0
GO:0030528 transcription regulator activity
10none
 
yes
at_TSS
43
719
5.9
3
1.98
4.812
0
0
GO:0003700 transcription factor activity
11none
 
yes
at_TSS
42
811
5.1
3
1.72
3.747
0.0001
0.0017
GO:0009653 morphogenesis
12none
 
 
before_TSS
42
101
41.5
25.6
1.61
3.669
0.0002
0.0445
GO:0006954 inflammatory response
13none
 
yes
at_TSS
39
674
5.7
3
1.92
4.346
0
0.0001
GO:0009887 organ morphogenesis
14none
 
 
after_TSS
37
155
23.8
15.6
1.52
2.835
0.0045
0.0698
GO:0004857 enzyme inhibitor activity
15none
 
 
after_TSS
37
144
25.6
15.6
1.64
3.337
0.0008
0.0163
GO:0005529 sugar binding
16none
 
yes
before_TSS
34
538
6.3
4
1.54
2.683
0.0072
0.0476
GO:0030154 cell differentiation
17none
 
 
before_TSS
30
70
42.8
25.6
1.66
3.295
0.0009
0.09
GO:0006913 nucleocytoplasmic transport
18none
 
yes
after_TSS
27
301
8.9
5.4
1.63
2.679
0.0073
0.075
GO:0007399 nervous system development
19none
 
yes
before_TSS
23
301
7.6
4
1.87
3.16
0.0015
0.0108
GO:0007399 nervous system development
20none
 
yes
at_TSS
19
301
6.3
3
2.09
3.399
0.0006
0.0103
GO:0007399 nervous system development
21none
 
yes
at_TSS
19
302
6.2
3
2.09
3.383
0.0007
0.0069
GO:0005667
22none
 
 
after_TSS
18
52
34.6
15.6
2.21
3.772
0.0001
0.0592
GO:0016835 carbon-oxygen lyase activity
23none
 
 
after_TSS
16
44
36.3
15.6
2.32
3.788
0.0001
0.0555
GO:0016836 hydro-lyase activity
24none
 
 
at_TSS
16
86
18.6
8.4
2.19
3.379
0.0007
0.0177
GO:0006399 tRNA metabolism
25none
 
yes
at_TSS
16
231
6.9
3
2.3
3.52
0.0004
0.0225
GO:0006366 transcription from RNA polymerase II promoter
26none
 
yes
before_TSS
15
170
8.8
4
2.16
3.146
0.0016
0.0252
GO:0009790 embryonic development
27none
 
yes
after_TSS
15
116
12.9
5.4
2.35
3.531
0.0004
0.0757
GO:0006897 endocytosis
28none
 
 
before_TSS
13
20
65
25.6
2.52
4.025
0
0.0208
GO:0042088 T-helper 1 type immune response
29none
 
yes
after_TSS
13
104
12.5
5.4
2.27
3.148
0.0016
0.0859
GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
30none
 
yes
after_TSS
13
103
12.6
5.4
2.29
3.187
0.0014
0.0876
GO:0045941 positive regulation of transcription
31none
 
 
before_TSS
13
21
61.9
25.6
2.4
3.8
0.0001
0.0529
GO:0042087 cell-mediated immune response
32none
 
 
after_TSS
12
24
50
15.6
3.19
4.636
0
0.0013
GO:0006909 phagocytosis
33MIT_012MYOD
 
 
after_TSS
21
379
5.5
2.3
2.38
4.228
0
0.0636
GO:0006955 immune response
34MIT_012MYOD
 
 
after_TSS
14
180
7.7
2.3
3.34
4.897
0
0.042
GO:0009611 response to wounding
35MIT_012MYOD
 
 
after_TSS
10
101
9.9
2.3
4.26
5.079
0
0.0163
GO:0006954 inflammatory response
36MIT_056PAX4
 
 
before_TSS
10
134
7.4
2
3.65
4.463
0
0.0873
GO:0005244 voltage-gated ion channel activity
37MIT_101
 
 
after_TSS
11
198
5.5
1.5
3.69
4.723
0
0.0502
GO:0005261 cation channel activity
38TF_CLOX
 
 
before_TSS
10
119
8.4
2
4.11
4.932
0
0.0175
GO:0007276 gametogenesis
39TF_CP2
 
 
before_TSS
21
401
5.2
1.9
2.62
4.731
0
0.0321
GO:0006812 cation transport
40TF_CP2
 
 
before_TSS
18
295
6.1
1.9
3.06
5.116
0
0.0134
GO:0015268 alpha-type channel activity
41TF_CP2
 
 
before_TSS
18
307
5.8
1.9
2.94
4.918
0
0.0377
GO:0015267 channel or pore class transporter activity
42TF_CP2
 
 
before_TSS
17
288
5.9
1.9
2.96
4.809
0
0.0218
GO:0030001 metal ion transport
43TF_CP2
 
 
before_TSS
17
269
6.3
1.9
3.17
5.138
0
0.012
GO:0005216 ion channel activity
44TF_CP2
 
 
before_TSS
17
259
6.5
1.9
3.29
5.324
0
0.0021
GO:0015672 monovalent inorganic cation transport
45TF_CP2
 
 
before_TSS
15
198
7.5
1.9
3.8
5.671
0
0.0006
GO:0005261 cation channel activity
46TF_CP2
 
 
before_TSS
11
135
8.1
1.9
4.09
5.149
0
0.0056
GO:0006813 potassium ion transport
47TF_CP2
 
 
before_TSS
11
134
8.2
1.9
4.12
5.18
0
0.0095
GO:0005244 voltage-gated ion channel activity
48TF_CP2
 
 
before_TSS
10
112
8.9
1.9
4.48
5.279
0
0.0056
GO:0005267 potassium channel activity
49TF_IRF
 
 
before_TSS
13
208
6.2
2.3
2.64
3.722
0.0001
0.0821
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
50TF_IRF
 
 
before_TSS
12
188
6.3
2.3
2.7
3.657
0.0002
0.0967
GO:0006323 DNA packaging
51TF_IRF
 
 
before_TSS
12
179
6.7
2.3
2.83
3.851
0.0001
0.0503
GO:0006325 establishment and/or maintenance of chromatin architecture
52TF_IRF
 
 
before_TSS
10
123
8.1
2.3
3.44
4.232
0
0.0099
GO:0006461 protein complex assembly
53TF_STAF
 
 
before_TSS
18
356
5
1.9
2.63
4.384
0
0.0629
GO:0005576
54TF_STAT
 
 
before_TSS
19
172
11
4.2
2.58
4.425
0
0.0833
GO:0003735 structural constituent of ribosome
55TF_STAT
 
 
before_TSS
11
70
15.7
4.2
3.67
4.747
0
0.0892
GO:0006913 nucleocytoplasmic transport