CisView Mouse (mm6, March 2005)

Main Gene Ontology terms for targets of TF_HNF1

No.GO annotation
Total
genes
with GO
Location
Max no. of
genes with
TF_HNF1
TF_HNF1 alone
In pair
with
1GO:0007275 development
1378
before_TSS
89
yes
 
2GO:0006950 response to stress
546
after_TSS
69
yes
 
3GO:0009605 response to external stimulus
489
at_TSS,after_TSS
68
yes
 
4GO:0048513 organ development
852
before_TSS
63
yes
 
5GO:0009653 morphogenesis
811
before_TSS
62
yes
 
6GO:0009607 response to biotic stimulus
483
after_TSS
61
yes
 
7GO:0006952 defense response
463
after_TSS
57
yes
 
8GO:0009887 organ morphogenesis
674
before_TSS
54
yes
 
9GO:0030154 cell differentiation
538
before_TSS
42
yes
 
10GO:0043207 response to external biotic stimulus
237
at_TSS,after_TSS
37
yes
 
11GO:0005386 carrier activity
394
at_TSS
36
yes
 
12GO:0005102 receptor binding
406
at_TSS
34
yes
 
13GO:0009613 response to pest, pathogen or parasite
221
at_TSS,after_TSS
31
yes
 
14GO:0007399 nervous system development
301
before_TSS
28
yes
 
15GO:0006457 protein folding
163
before_TSS
24
 
MIT_055NFAT,
16GO:0004857 enzyme inhibitor activity
155
at_TSS
22
yes
 
17GO:0005529 sugar binding
144
at_TSS,before_TSS,after_TSS
21
yes
ADD_OCT4A,
18GO:0007600 sensory perception
196
at_TSS
20
yes
 
19GO:0015290 electrochemical potential-driven transporter activity
171
at_TSS
20
yes
 
20GO:0015291 porter activity
170
at_TSS
20
yes
 
21GO:0006461 protein complex assembly
123
before_TSS
19
 
MIT_060FOXO,
22GO:0004866 endopeptidase inhibitor activity
112
at_TSS
17
yes
 
23GO:0030414 protease inhibitor activity
112
at_TSS
17
yes
 
24GO:0006928 cell motility
162
before_TSS
16
yes
 
25GO:0040011 locomotion
165
before_TSS
16
yes
 
26GO:0007626 locomotory behavior
187
before_TSS
16
yes
 
27GO:0004497 monooxygenase activity
90
after_TSS
16
yes
 
28GO:0005179 hormone activity
97
at_TSS
15
yes
 
29GO:0016337 cell-cell adhesion
99
at_TSS
15
yes
 
30GO:0048468 cell development
162
before_TSS
15
yes
 
31GO:0009790 embryonic development
170
before_TSS
15
yes
 
32GO:0007417 central nervous system development
76
before_TSS
14
yes
 
33GO:0007167 enzyme linked receptor protein signaling pathway
157
before_TSS
14
yes
 
34GO:0007389 pattern specification
128
before_TSS
13
yes
 
35GO:0030182 neuron differentiation
137
before_TSS
13
yes
 
36GO:0007156 homophilic cell adhesion
76
at_TSS
13
yes
 
37GO:0031175 neurite morphogenesis
96
before_TSS
12
yes
 
38GO:0048667 neuron morphogensis during differentiation
96
before_TSS
12
yes
 
39GO:0000904 cellular morphogenesis during differentiation
107
before_TSS
12
yes
 
40GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
208
before_TSS
12
 
MIT_170,
41GO:0008202 steroid metabolism
90
at_TSS
12
yes
 
42GO:0051276 chromosome organization and biogenesis
220
before_TSS
12
 
MIT_170,
43GO:0015293 symporter activity
78
at_TSS
12
yes
 
44GO:0048666 neuron development
108
before_TSS
12
yes
 
45GO:0004867 serine-type endopeptidase inhibitor activity
77
at_TSS
12
yes
 
46GO:0016789 carboxylic ester hydrolase activity
80
at_TSS
11
yes
 
47GO:0007420 brain development
63
before_TSS
11
yes
 
48GO:0006325 establishment and/or maintenance of chromatin architecture
179
before_TSS
10
 
MIT_170,
49GO:0006334 nucleosome assembly
86
at_TSS
10
yes
 
50GO:0004519 endonuclease activity
70
before_TSS
10
 
TF_PBX,
51GO:0007409 axonogenesis
81
before_TSS
10
yes
 
52GO:0016055 Wnt receptor signaling pathway
81
before_TSS
10
 
MIT_024MAZ,

Pairs of TF_HNF1 binding sites with other TFBS

No.TFBS
Location
Total GO-s
Main GO annotation
N pairs for
main GO
Total genes
for main GO
1MIT_170
before_TSS
3
GO:0051276 chromosome organization and biogenesis
12
220
2ADD_OCT4A
before_TSS
1
GO:0005529 sugar binding
11
144
3MIT_024MAZ
before_TSS
1
GO:0016055 Wnt receptor signaling pathway
10
81
4MIT_055NFAT
before_TSS
1
GO:0006457 protein folding
24
163
5TF_PBX
before_TSS
1
GO:0004519 endonuclease activity
10
70
6MIT_060FOXO
before_TSS
1
GO:0006461 protein complex assembly
19
123

Details on Gene Ontology terms for targets of TF_HNF1

Total number of genes = 12103
No.In pair
with
Multi-
ple
Conser-
ved
Location
Frequency
in list
U-clusters
in list
Genes with TFBS
in list, %
Genes with TFBS
total, %
Ratio
z
p
FDR
GO annotation
1none
 
yes
before_TSS
89
1378
6.4
4.2
1.51
4.284
0
0.0001
GO:0007275 development
2none
 
 
after_TSS
69
546
12.6
8.1
1.54
3.88
0.0001
0.0382
GO:0006950 response to stress
3none
 
 
after_TSS
68
489
13.9
8.1
1.69
4.707
0
0.0001
GO:0009605 response to external stimulus
4none
 
yes
before_TSS
63
852
7.3
4.2
1.73
4.691
0
0
GO:0048513 organ development
5none
 
yes
before_TSS
62
811
7.6
4.2
1.79
4.934
0
0
GO:0009653 morphogenesis
6none
 
 
after_TSS
61
483
12.6
8.1
1.54
3.633
0.0002
0.0031
GO:0009607 response to biotic stimulus
7none
 
 
after_TSS
57
463
12.3
8.1
1.5
3.299
0.0009
0.0073
GO:0006952 defense response
8none
 
yes
before_TSS
54
674
8
4.2
1.87
4.956
0
0
GO:0009887 organ morphogenesis
9none
 
 
at_TSS
44
489
8.9
5
1.76
4.002
0
0.0012
GO:0009605 response to external stimulus
10none
 
yes
before_TSS
42
538
7.8
4.2
1.83
4.161
0
0.0009
GO:0030154 cell differentiation
11none
 
 
after_TSS
37
237
15.6
8.1
1.9
4.209
0
0.001
GO:0043207 response to external biotic stimulus
12none
 
 
at_TSS
36
394
9.1
5
1.79
3.705
0.0002
0.0773
GO:0005386 carrier activity
13none
 
 
at_TSS
34
406
8.3
5
1.64
3.053
0.0022
0.046
GO:0005102 receptor binding
14none
 
 
at_TSS
34
356
9.5
5
1.87
3.876
0.0001
0.0027
GO:0005576
15none
 
 
after_TSS
31
221
14
8.1
1.71
3.195
0.0013
0.0165
GO:0009613 response to pest, pathogen or parasite
16none
 
yes
before_TSS
28
301
9.3
4.2
2.18
4.381
0
0.0002
GO:0007399 nervous system development
17none
 
 
at_TSS
22
237
9.2
5
1.82
2.957
0.0031
0.0307
GO:0043207 response to external biotic stimulus
18none
 
 
at_TSS
22
155
14.1
5
2.78
5.181
0
0
GO:0004857 enzyme inhibitor activity
19none
 
 
at_TSS
21
221
9.5
5
1.86
3.004
0.0026
0.0295
GO:0009613 response to pest, pathogen or parasite
20none
 
 
after_TSS
21
144
14.5
8.1
1.78
2.815
0.0048
0.0557
GO:0005529 sugar binding
21none
 
 
at_TSS
20
170
11.7
5
2.3
3.979
0
0.0253
GO:0015291 porter activity
22none
 
 
at_TSS
20
171
11.6
5
2.29
3.95
0
0.0286
GO:0015290 electrochemical potential-driven transporter activity
23none
 
 
at_TSS
20
196
10.2
5
2
3.276
0.001
0.0296
GO:0007600 sensory perception
24none
 
yes
at_TSS
19
364
5.2
1.9
2.69
4.623
0
0.0013
GO:0005887
25none
 
 
at_TSS
17
112
15.1
5
2.97
4.872
0
0.0002
GO:0004866 endopeptidase inhibitor activity
26none
 
 
at_TSS
17
112
15.1
5
2.97
4.872
0
0.0002
GO:0030414 protease inhibitor activity
27none
 
 
after_TSS
16
90
17.7
8.1
2.17
3.33
0.0008
0.0186
GO:0004497 monooxygenase activity
28none
 
yes
before_TSS
16
165
9.6
4.2
2.27
3.478
0.0005
0.0132
GO:0040011 locomotion
29none
 
yes
before_TSS
16
187
8.5
4.2
2
2.928
0.0034
0.0567
GO:0007626 locomotory behavior
30none
 
yes
before_TSS
16
162
9.8
4.2
2.31
3.56
0.0003
0.0113
GO:0006928 cell motility
31none
 
 
at_TSS
15
97
15.4
5
3.03
4.66
0
0.0002
GO:0005179 hormone activity
32none
 
 
at_TSS
15
144
10.4
5
2.04
2.919
0.0035
0.0676
GO:0005529 sugar binding
33none
 
 
at_TSS
15
99
15.1
5
2.97
4.566
0
0.0018
GO:0016337 cell-cell adhesion
34none
 
yes
before_TSS
15
162
9.2
4.2
2.17
3.168
0.0015
0.0255
GO:0048468 cell development
35none
 
yes
before_TSS
15
170
8.8
4.2
2.06
2.963
0.003
0.0412
GO:0009790 embryonic development
36none
 
yes
before_TSS
14
157
8.9
4.2
2.09
2.905
0.0036
0.079
GO:0007167 enzyme linked receptor protein signaling pathway
37none
 
 
after_TSS
14
60
23.3
8.1
2.84
4.289
0
0.0016
GO:0009897
38none
 
yes
before_TSS
14
76
18.4
4.2
4.32
6.128
0
0
GO:0007417 central nervous system development
39none
 
yes
before_TSS
13
128
10.1
4.2
2.38
3.317
0.0009
0.0079
GO:0007389 pattern specification
40none
 
yes
before_TSS
13
137
9.4
4.2
2.22
3.044
0.0023
0.0267
GO:0030182 neuron differentiation
41none
 
 
at_TSS
13
76
17.1
5
3.35
4.773
0
0.0006
GO:0007156 homophilic cell adhesion
42none
 
 
at_TSS
12
77
15.5
5
3.05
4.196
0
0.0049
GO:0004867 serine-type endopeptidase inhibitor activity
43none
 
 
at_TSS
12
90
13.3
5
2.61
3.565
0.0003
0.0443
GO:0008202 steroid metabolism
44none
 
yes
before_TSS
12
108
11.1
4.2
2.6
3.538
0.0004
0.0134
GO:0048666 neuron development
45none
 
yes
before_TSS
12
96
12.5
4.2
2.93
4.01
0
0.0037
GO:0031175 neurite morphogenesis
46none
 
yes
before_TSS
12
96
12.5
4.2
2.93
4.01
0
0.0037
GO:0048667 neuron morphogensis during differentiation
47none
 
 
at_TSS
12
78
15.3
5
3.01
4.143
0
0.0125
GO:0015293 symporter activity
48none
 
yes
before_TSS
12
107
11.2
4.2
2.63
3.574
0.0003
0.0128
GO:0000904 cellular morphogenesis during differentiation
49none
 
 
at_TSS
11
80
13.7
5
2.69
3.529
0.0004
0.0763
GO:0016789 carboxylic ester hydrolase activity
50none
 
yes
before_TSS
11
63
17.4
4.2
4.09
5.198
0
0
GO:0007420 brain development
51none
 
yes
before_TSS
10
81
12.3
4.2
2.89
3.612
0.0003
0.0111
GO:0007409 axonogenesis
52none
 
 
at_TSS
10
86
11.6
5
2.28
2.762
0.0057
0.0841
GO:0006334 nucleosome assembly
53ADD_OCT4A
 
 
before_TSS
11
144
7.6
2.2
3.37
4.361
0
0.0254
GO:0005529 sugar binding
54MIT_024MAZ
 
 
before_TSS
10
81
12.3
2.7
4.56
5.37
0
0.0034
GO:0016055 Wnt receptor signaling pathway
55MIT_055NFAT
 
 
before_TSS
24
163
14.7
5.5
2.66
5.18
0
0.0095
GO:0006457 protein folding
56MIT_060FOXO
 
 
before_TSS
19
123
15.4
7
2.19
3.669
0.0002
0.0848
GO:0006461 protein complex assembly
57MIT_170
 
 
before_TSS
12
208
5.7
1.8
3.11
4.229
0
0.0125
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
58MIT_170
 
 
before_TSS
12
220
5.4
1.8
2.94
4.002
0
0.0304
GO:0051276 chromosome organization and biogenesis
59MIT_170
 
 
before_TSS
10
179
5.5
1.8
3.01
3.736
0.0001
0.0748
GO:0006325 establishment and/or maintenance of chromatin architecture
60TF_MEIS
 
 
before_TSS
10
88
11.3
3.1
3.58
4.399
0
0.0046
GO:0005694
61TF_PBX
 
 
before_TSS
10
70
14.2
3.2
4.33
5.164
0
0.0052
GO:0004519 endonuclease activity