CisView Mouse (mm6, March 2005)

Main Gene Ontology terms for targets of TF_HTF

No.GO annotation
Total
genes
with GO
Location
Max no. of
genes with
TF_HTF
TF_HTF alone
In pair
with
1GO:0009653 morphogenesis
811
before_TSS
125
yes
 
2GO:0009887 organ morphogenesis
674
before_TSS
112
yes
 
3GO:0030528 transcription regulator activity
941
before_TSS
91
 
TF_AP2,
4GO:0046907 intracellular transport
478
at_TSS
87
 
many
5GO:0030154 cell differentiation
538
before_TSS
84
yes
 
6GO:0008104 protein localization
508
at_TSS
82
yes
many
7GO:0015031 protein transport
476
at_TSS
79
yes
many
8GO:0045184 establishment of protein localization
492
at_TSS
79
yes
many
9GO:0006259 DNA metabolism
427
before_TSS,after_TSS
76
 
many
10GO:0016043 cell organization and biogenesis
839
after_TSS
75
 
TF_CREB, ADD_LRH,
11GO:0006996 organelle organization and biogenesis
645
after_TSS
71
 
TF_ATF1, TF_CREB, ADD_LRH,
12GO:0007399 nervous system development
301
at_TSS,before_TSS,after_TSS
68
yes
TF_RFX1, TF_MAZR,
13GO:0006886 intracellular protein transport
350
at_TSS
67
yes
many
14GO:0007049 cell cycle
443
before_TSS
65
 
TF_SP1, TF_RFX, MIT_006SP1,
15GO:0004386 helicase activity
108
at_TSS,after_TSS
61
yes
many
16GO:0051276 chromosome organization and biogenesis
220
before_TSS,after_TSS
58
yes
many
17GO:0016070 RNA metabolism
342
after_TSS
58
 
TF_ELK,
18GO:0003723 RNA binding
354
at_TSS,after_TSS
55
yes
many
19GO:0043118 negative regulation of physiological process
342
before_TSS
54
yes
 
20GO:0051243 negative regulation of cellular physiological process
330
before_TSS
53
yes
 
21GO:0008026 ATP-dependent helicase activity
86
after_TSS
52
yes
TF_GABP, TF_ELK,
22GO:0043037 translation
128
at_TSS,after_TSS
52
yes
MIT_024MAZ, MIT_101,
23GO:0006323 DNA packaging
188
after_TSS
51
yes
many
24GO:0006396 RNA processing
273
at_TSS,after_TSS
51
 
TF_AHR, MIT_030, TF_ELK,
25GO:0008565 protein transporter activity
120
at_TSS
49
yes
MIT_140, TF_ELK, TF_ETS,
26GO:0006334 nucleosome assembly
86
after_TSS
47
yes
many
27GO:0045182 translation regulator activity
90
at_TSS,before_TSS,after_TSS
46
yes
many
28GO:0008135 translation factor activity, nucleic acid binding
86
at_TSS,before_TSS,after_TSS
45
yes
many
29GO:0006512 ubiquitin cycle
390
at_TSS,before_TSS
45
 
TF_AP2, TF_ELK,
30GO:0016071 mRNA metabolism
202
after_TSS
45
 
TF_AP2, TF_AP2A,
31GO:0004518 nuclease activity
108
at_TSS
45
yes
 
32GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
208
after_TSS
44
yes
many
33GO:0006366 transcription from RNA polymerase II promoter
231
before_TSS
42
yes
TF_SP1,
34GO:0006397 mRNA processing
189
at_TSS,after_TSS
41
 
many
35GO:0006325 establishment and/or maintenance of chromatin architecture
179
after_TSS
41
yes
many
36GO:0016887 ATPase activity
280
at_TSS,after_TSS
40
 
TF_ZID, TF_GABP, TF_ELK,
37GO:0007028 cytoplasm organization and biogenesis
82
at_TSS
38
yes
many
38GO:0007610 behavior
229
before_TSS
38
yes
MIT_024MAZ,
39GO:0006399 tRNA metabolism
86
at_TSS
37
yes
 
40GO:0006260 DNA replication
90
at_TSS
37
yes
many
41GO:0009790 embryonic development
170
before_TSS
36
yes
 
42GO:0042254 ribosome biogenesis and assembly
74
at_TSS
35
yes
many
43GO:0006333 chromatin assembly or disassembly
121
before_TSS,after_TSS
34
yes
many
44GO:0048468 cell development
162
before_TSS
34
yes
 
45GO:0006357 regulation of transcription from RNA polymerase II promoter
191
before_TSS
34
yes
 
46GO:0007389 pattern specification
128
after_TSS
33
yes
 
47GO:0008380 RNA splicing
154
after_TSS
33
 
many
48GO:0007626 locomotory behavior
187
before_TSS
33
yes
TF_SREBP,
49GO:0007046 ribosome biogenesis
67
at_TSS
33
yes
many
50GO:0000398 nuclear mRNA splicing, via spliceosome
149
after_TSS
32
 
many
51GO:0006461 protein complex assembly
123
after_TSS
32
yes
many
52GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
149
after_TSS
32
 
many
53GO:0000375 RNA splicing, via transesterification reactions
149
after_TSS
32
 
many
54GO:0030182 neuron differentiation
137
at_TSS,before_TSS
32
yes
 
55GO:0006913 nucleocytoplasmic transport
70
at_TSS
31
yes
 
56GO:0040011 locomotion
165
before_TSS
31
yes
TF_SREBP,
57GO:0016773 phosphotransferase activity, alcohol group as acceptor
553
before_TSS
31
 
TF_TAXCREB1,
58GO:0009892 negative regulation of metabolism
149
before_TSS
31
yes
TF_AHR, TF_MAZR,
59GO:0006928 cell motility
162
before_TSS
30
yes
 
60GO:0009059 macromolecule biosynthesis
472
at_TSS,after_TSS
30
 
TF_SP1, MIT_022,
61GO:0003743 translation initiation factor activity
53
at_TSS,before_TSS,after_TSS
29
yes
many
62GO:0031497 chromatin assembly
95
after_TSS
29
yes
many
63GO:0031324 negative regulation of cellular metabolism
132
before_TSS
29
yes
TF_AHR, TF_P300,
64GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
121
before_TSS
27
yes
 
65GO:0016481 negative regulation of transcription
115
before_TSS
26
yes
TF_AHR,
66GO:0003735 structural constituent of ribosome
172
after_TSS
26
yes
 
67GO:0016477 cell migration
141
before_TSS
25
yes
 
68GO:0000904 cellular morphogenesis during differentiation
107
before_TSS
24
yes
 
69GO:0008134 transcription factor binding
110
before_TSS
23
yes
 
70GO:0006412 protein biosynthesis
421
at_TSS
22
 
MIT_022,
71GO:0048666 neuron development
108
before_TSS
22
yes
 
72GO:0008047 enzyme activator activity
127
before_TSS
22
 
MIT_006SP1,
73GO:0031175 neurite morphogenesis
96
before_TSS
21
yes
 
74GO:0048667 neuron morphogensis during differentiation
96
before_TSS
21
yes
 
75GO:0042127 regulation of cell proliferation
139
before_TSS
21
 
TF_PAX3, TF_MAZR,
76GO:0003712 transcription cofactor activity
94
before_TSS
21
yes
 
77GO:0051169 nuclear transport
63
at_TSS
20
yes
 
78GO:0005975 carbohydrate metabolism
308
before_TSS
20
 
MIT_006SP1,
79GO:0007409 axonogenesis
81
before_TSS
20
yes
 
80GO:0046903 secretion
123
at_TSS
19
 
MIT_003ELK, TF_GABP, TF_ELK,
81GO:0006413 translational initiation
36
at_TSS,before_TSS
19
yes
many
82GO:0007417 central nervous system development
76
before_TSS
19
yes
 
83GO:0009792 embryonic development (sensu Metazoa)
85
before_TSS
18
yes
 
84GO:0007420 brain development
63
before_TSS
18
yes
 
85GO:0008033 tRNA processing
32
at_TSS
18
yes
 
86GO:0006261 DNA-dependent DNA replication
32
at_TSS
17
yes
TF_ELK,
87GO:0045045 secretory pathway
101
at_TSS
17
 
MIT_003ELK, TF_GABP, TF_ELK,
88GO:0016564 transcriptional repressor activity
64
before_TSS
16
yes
 
89GO:0051168 nuclear export
26
at_TSS
16
yes
 
90GO:0016072 rRNA metabolism
31
at_TSS
16
yes
TF_GABP, TF_ELK,
91GO:0007411 axon guidance
45
before_TSS
15
yes
 
92GO:0044262 cellular carbohydrate metabolism
205
at_TSS
14
 
MIT_101,
93GO:0042623 ATPase activity, coupled
256
at_TSS
14
 
TF_ZID,
94GO:0000279 M phase
122
at_TSS
14
 
MIT_001NRF1, MIT_022, TF_E2F,
95GO:0035295 tube development
61
before_TSS
14
yes
 
96GO:0051186 cofactor metabolism
181
after_TSS
14
 
TF_ZID,
97GO:0006403 RNA localization
22
at_TSS
13
yes
 
98GO:0000902 cellular morphogenesis
238
before_TSS
13
yes
 
99GO:0008168 methyltransferase activity
98
after_TSS
13
 
MIT_101,

Pairs of TF_HTF binding sites with other TFBS

No.TFBS
Location
Total GO-s
Main GO annotation
N pairs for
main GO
Total genes
for main GO
1TF_ELK
at_TSS,before_TSS,after_TSS
25
GO:0046907 intracellular transport
87
478
2TF_AHR
at_TSS,before_TSS,after_TSS
23
GO:0006259 DNA metabolism
76
427
3TF_GABP
at_TSS,after_TSS
16
GO:0008104 protein localization
60
508
4TF_ETS
at_TSS,after_TSS
16
GO:0046907 intracellular transport
50
478
5TF_CREB
at_TSS,before_TSS,after_TSS
14
GO:0016043 cell organization and biogenesis
75
839
6MIT_001NRF1
at_TSS,after_TSS
12
GO:0045182 translation regulator activity
13
90
7ADD_LRH
after_TSS
11
GO:0016043 cell organization and biogenesis
60
839
8TF_ATF1
after_TSS
10
GO:0006996 organelle organization and biogenesis
71
645
9TF_NF1
after_TSS
9
GO:0006259 DNA metabolism
28
427
10TF_ARNT
at_TSS,before_TSS,after_TSS
8
GO:0008104 protein localization
45
508
11TF_TAXCREB1
before_TSS,after_TSS
8
GO:0016773 phosphotransferase activity, alcohol group as acceptor
31
553
12TF_AP2
at_TSS,before_TSS,after_TSS
8
GO:0030528 transcription regulator activity
91
941
13TF_PAX4
after_TSS
7
GO:0003723 RNA binding
24
354
14MIT_003ELK
at_TSS
7
GO:0008104 protein localization
39
508
15TF_AP2A
after_TSS
6
GO:0016071 mRNA metabolism
45
202
16TF_SP1
at_TSS,before_TSS,after_TSS
6
GO:0007049 cell cycle
65
443
17MIT_022
at_TSS
5
GO:0009059 macromolecule biosynthesis
25
472
18MIT_024MAZ
before_TSS,after_TSS
4
GO:0043037 translation
20
128
19TF_ZID
at_TSS,after_TSS
4
GO:0016887 ATPase activity
14
280
20MIT_140
at_TSS
4
GO:0015031 protein transport
28
476
21MIT_006SP1
at_TSS,before_TSS,after_TSS
4
GO:0007049 cell cycle
58
443
22MIT_019
at_TSS,after_TSS
3
GO:0045182 translation regulator activity
11
90
23TF_MAZR
at_TSS,before_TSS
3
GO:0007399 nervous system development
21
301
24MIT_101
at_TSS,after_TSS
3
GO:0044262 cellular carbohydrate metabolism
14
205
25TF_E2F
at_TSS,before_TSS
3
GO:0006259 DNA metabolism
28
427
26TF_HTF
before_TSS,after_TSS
3
GO:0003743 translation initiation factor activity
11
53
27TF_SREBP
before_TSS
2
GO:0007626 locomotory behavior
23
187
28TF_ATF6
before_TSS
2
GO:0003743 translation initiation factor activity
11
53
29TF_NFY
at_TSS
2
GO:0006260 DNA replication
13
90
30TF_MRF2
before_TSS
2
GO:0045182 translation regulator activity
10
90
31TF_RFX
at_TSS,before_TSS
2
GO:0007049 cell cycle
38
443
32TF_PAX3
at_TSS,before_TSS
2
GO:0006397 mRNA processing
10
189
33MIT_041MEIS
after_TSS
2
GO:0006323 DNA packaging
10
188
34TF_STAT
after_TSS
1
GO:0006461 protein complex assembly
10
123
35TF_RFX1
after_TSS
1
GO:0007399 nervous system development
24
301
36MIT_045
after_TSS
1
GO:0006333 chromatin assembly or disassembly
13
121
37TF_EGR1
at_TSS
1
GO:0003723 RNA binding
25
354
38TF_ER
after_TSS
1
GO:0006461 protein complex assembly
11
123
39MIT_030
at_TSS
1
GO:0006396 RNA processing
18
273
40MIT_083HNF3
before_TSS
1
GO:0016779 nucleotidyltransferase activity
12
91
41TF_MYB
at_TSS
1
GO:0006457 protein folding
11
163
42TF_HNF4
after_TSS
1
GO:0003723 RNA binding
22
354
43MIT_012MYOD
after_TSS
1
GO:0004540 ribonuclease activity
10
42
44TF_P300
before_TSS
1
GO:0031324 negative regulation of cellular metabolism
13
132
45MIT_152
before_TSS
1
GO:0007167 enzyme linked receptor protein signaling pathway
11
157

Details on Gene Ontology terms for targets of TF_HTF

Total number of genes = 12103
No.In pair
with
Multi-
ple
Conser-
ved
Location
Frequency
in list
U-clusters
in list
Genes with TFBS
in list, %
Genes with TFBS
total, %
Ratio
z
p
FDR
GO annotation
1none
 
yes
before_TSS
125
811
15.4
10.1
1.52
5.172
0
0
GO:0009653 morphogenesis
2none
 
yes
before_TSS
112
674
16.6
10.1
1.64
5.753
0
0
GO:0009887 organ morphogenesis
3none
 
yes
before_TSS
84
538
15.6
10.1
1.54
4.32
0
0.0006
GO:0030154 cell differentiation
4none
 
yes
after_TSS
79
302
26.1
16
1.63
4.849
0
0
GO:0005667
5none
 
yes
at_TSS
68
301
22.5
13.6
1.65
4.565
0
0.0001
GO:0007399 nervous system development
6none
 
yes
before_TSS
62
301
20.5
10.1
2.03
6.102
0
0
GO:0007399 nervous system development
7none
 
yes
at_TSS
61
288
21.1
13.6
1.54
3.757
0.0001
0.0209
GO:0005794
8none
 
 
after_TSS
61
108
56.4
36.3
1.55
4.369
0
0.0022
GO:0004386 helicase activity
9none
 
yes
after_TSS
58
220
26.3
16
1.64
4.207
0
0.0011
GO:0051276 chromosome organization and biogenesis
10none
 
yes
before_TSS
56
302
18.5
10.1
1.83
4.913
0
0
GO:0005667
11none
 
yes
before_TSS
54
342
15.7
10.1
1.56
3.525
0.0004
0.011
GO:0043118 negative regulation of physiological process
12none
 
yes
before_TSS
53
330
16
10.1
1.58
3.626
0.0002
0.0087
GO:0051243 negative regulation of cellular physiological process
13none
yes
 
at_TSS
52
508
10.2
5.5
1.86
4.779
0
0.0001
GO:0008104 protein localization
14none
 
 
at_TSS
52
128
40.6
26.9
1.5
3.517
0.0004
0.0177
GO:0043037 translation
15none
yes
 
at_TSS
52
492
10.5
5.5
1.92
5.031
0
0
GO:0045184 establishment of protein localization
16none
 
 
after_TSS
52
86
60.4
36.3
1.66
4.666
0
0.0011
GO:0008026 ATP-dependent helicase activity
17none
yes
 
at_TSS
51
476
10.7
5.5
1.94
5.087
0
0
GO:0015031 protein transport
18none
 
yes
after_TSS
51
188
27.1
16
1.69
4.172
0
0.0015
GO:0006323 DNA packaging
19none
yes
 
after_TSS
50
354
14.1
8.6
1.63
3.718
0.0002
0.0033
GO:0003723 RNA binding
20none
 
 
at_TSS
49
120
40.8
26.9
1.51
3.455
0.0005
0.0335
GO:0008565 protein transporter activity
21none
 
 
after_TSS
48
88
54.5
36.3
1.5
3.562
0.0003
0.0064
GO:0005694
22none
 
 
after_TSS
47
86
54.6
36.3
1.5
3.541
0.0003
0.0058
GO:0006334 nucleosome assembly
23none
 
 
at_TSS
46
90
51.1
26.9
1.89
5.195
0
0
GO:0045182 translation regulator activity
24none
 
 
at_TSS
45
86
52.3
26.9
1.94
5.333
0
0
GO:0008135 translation factor activity, nucleic acid binding
25none
 
 
at_TSS
45
108
41.6
26.9
1.54
3.473
0.0005
0.0376
GO:0004518 nuclease activity
26none
 
 
after_TSS
44
78
56.4
36.3
1.55
3.695
0.0002
0.0033
GO:0000786
27none
 
yes
before_TSS
42
231
18.1
10.1
1.79
4.1
0
0.0075
GO:0006366 transcription from RNA polymerase II promoter
28none
yes
 
at_TSS
40
350
11.4
5.5
2.07
4.933
0
0.0001
GO:0006886 intracellular protein transport
29none
 
 
at_TSS
38
82
46.3
26.9
1.72
3.98
0
0.0018
GO:0007028 cytoplasm organization and biogenesis
30none
 
yes
before_TSS
38
229
16.5
10.1
1.63
3.278
0.001
0.0212
GO:0007610 behavior
31none
 
 
at_TSS
37
86
43
26.9
1.59
3.381
0.0007
0.0188
GO:0006399 tRNA metabolism
32none
 
 
at_TSS
37
90
41.1
26.9
1.52
3.048
0.0023
0.0702
GO:0006260 DNA replication
33none
 
yes
before_TSS
36
170
21.1
10.1
2.09
4.812
0
0.0001
GO:0009790 embryonic development
34none
yes
 
at_TSS
36
354
10.1
5.5
1.84
3.907
0
0.0014
GO:0003723 RNA binding
35none
 
 
at_TSS
35
74
47.2
26.9
1.75
3.966
0
0.0022
GO:0042254 ribosome biogenesis and assembly
36none
 
yes
before_TSS
34
162
20.9
10.1
2.07
4.616
0
0.0002
GO:0048468 cell development
37none
yes
 
after_TSS
34
220
15.4
8.6
1.78
3.622
0.0002
0.0066
GO:0051276 chromosome organization and biogenesis
38none
 
yes
before_TSS
34
191
17.8
10.1
1.75
3.546
0.0003
0.0238
GO:0006357 regulation of transcription from RNA polymerase II promoter
39none
 
yes
after_TSS
33
128
25.7
16
1.6
3.016
0.0025
0.0246
GO:0007389 pattern specification
40none
yes
 
after_TSS
33
208
15.8
8.6
1.83
3.733
0.0001
0.0046
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
41none
 
 
at_TSS
33
67
49.2
26.9
1.83
4.135
0
0.0011
GO:0007046 ribosome biogenesis
42none
 
yes
before_TSS
33
187
17.6
10.1
1.74
3.438
0.0005
0.0214
GO:0007626 locomotory behavior
43none
 
yes
at_TSS
32
137
23.3
13.6
1.7
3.321
0.0008
0.0328
GO:0030182 neuron differentiation
44none
 
yes
before_TSS
31
165
18.7
10.1
1.85
3.716
0.0002
0.0082
GO:0040011 locomotion
45none
 
 
at_TSS
31
70
44.2
26.9
1.64
3.287
0.001
0.0926
GO:0006913 nucleocytoplasmic transport
46none
 
yes
before_TSS
31
149
20.8
10.1
2.05
4.35
0
0.0008
GO:0009892 negative regulation of metabolism
47none
 
yes
before_TSS
30
162
18.5
10.1
1.82
3.567
0.0003
0.012
GO:0006928 cell motility
48none
 
yes
before_TSS
30
137
21.8
10.1
2.16
4.595
0
0.0002
GO:0030182 neuron differentiation
49none
yes
 
after_TSS
30
188
15.9
8.6
1.84
3.591
0.0003
0.0075
GO:0006323 DNA packaging
50none
yes
 
after_TSS
30
179
16.7
8.6
1.93
3.888
0.0001
0.0023
GO:0006325 establishment and/or maintenance of chromatin architecture
51none
 
yes
before_TSS
29
132
21.9
10.1
2.17
4.537
0
0.0006
GO:0031324 negative regulation of cellular metabolism
52none
 
 
at_TSS
29
53
54.7
26.9
2.03
4.574
0
0.0004
GO:0003743 translation initiation factor activity
53none
yes
 
at_TSS
27
288
9.3
5.5
1.7
2.916
0.0035
0.0926
GO:0005794
54none
 
yes
before_TSS
27
121
22.3
10.1
2.2
4.468
0
0.0005
GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
55none
 
yes
before_TSS
26
115
22.6
10.1
2.23
4.46
0
0.0004
GO:0016481 negative regulation of transcription
56none
yes
 
after_TSS
26
172
15.1
8.6
1.74
3.037
0.0023
0.0583
GO:0003735 structural constituent of ribosome
57none
 
 
at_TSS
26
58
44.8
26.9
1.66
3.083
0.002
0.075
GO:0005730
58none
 
yes
before_TSS
25
141
17.7
10.1
1.75
3.013
0.0025
0.0631
GO:0016477 cell migration
59none
yes
 
after_TSS
25
123
20.3
8.6
2.34
4.629
0
0
GO:0006461 protein complex assembly
60none
 
yes
before_TSS
24
107
22.4
10.1
2.21
4.239
0
0.0013
GO:0000904 cellular morphogenesis during differentiation
61none
yes
 
after_TSS
23
121
19
8.6
2.19
4.073
0
0.0009
GO:0006333 chromatin assembly or disassembly
62none
 
yes
before_TSS
23
110
20.9
10.1
2.06
3.768
0.0001
0.015
GO:0008134 transcription factor binding
63none
yes
 
after_TSS
23
95
24.2
8.6
2.79
5.416
0
0
GO:0031497 chromatin assembly
64none
 
yes
before_TSS
22
108
20.3
10.1
2.01
3.547
0.0003
0.0142
GO:0048666 neuron development
65none
 
yes
before_TSS
21
94
22.3
10.1
2.2
3.942
0
0.0098
GO:0003712 transcription cofactor activity
66none
yes
 
after_TSS
21
88
23.8
8.6
2.75
5.094
0
0
GO:0005694
67none
 
yes
before_TSS
21
96
21.8
10.1
2.16
3.833
0.0001
0.0051
GO:0031175 neurite morphogenesis
68none
 
yes
before_TSS
21
96
21.8
10.1
2.16
3.833
0.0001
0.0051
GO:0048667 neuron morphogensis during differentiation
69none
yes
 
after_TSS
21
86
24.4
8.6
2.82
5.22
0
0
GO:0006334 nucleosome assembly
70none
yes
 
after_TSS
20
78
25.6
8.6
2.96
5.354
0
0
GO:0000786
71none
 
yes
at_TSS
20
63
31.7
13.6
2.32
4.188
0
0.0103
GO:0051169 nuclear transport
72none
 
yes
before_TSS
20
81
24.6
10.1
2.43
4.362
0
0.0009
GO:0007409 axonogenesis
73none
 
 
at_TSS
19
36
52.7
26.9
1.96
3.504
0.0004
0.0239
GO:0006413 translational initiation
74none
 
yes
before_TSS
19
76
25
10.1
2.47
4.313
0
0.0004
GO:0007417 central nervous system development
75none
 
yes
before_TSS
18
63
28.5
10.1
2.82
4.867
0
0
GO:0007420 brain development
76none
 
 
at_TSS
18
32
56.2
26.9
2.09
3.747
0.0001
0.0218
GO:0008033 tRNA processing
77none
 
yes
before_TSS
18
85
21.1
10.1
2.09
3.391
0.0006
0.0318
GO:0009792 embryonic development (sensu Metazoa)
78none
yes
 
before_TSS
17
53
32
14.2
2.25
3.735
0.0001
0.0687
GO:0003743 translation initiation factor activity
79none
 
 
at_TSS
17
32
53.1
26.9
1.97
3.347
0.0008
0.0747
GO:0006261 DNA-dependent DNA replication
80none
 
yes
before_TSS
16
64
25
10.1
2.47
3.956
0
0.0055
GO:0016564 transcriptional repressor activity
81none
yes
 
after_TSS
16
86
18.6
8.6
2.15
3.295
0.0009
0.0327
GO:0008135 translation factor activity, nucleic acid binding
82none
 
 
at_TSS
16
31
51.6
26.9
1.91
3.105
0.0019
0.0773
GO:0016072 rRNA metabolism
83none
 
 
at_TSS
16
26
61.5
26.9
2.28
3.985
0
0.0123
GO:0051168 nuclear export
84none
yes
 
after_TSS
16
90
17.7
8.6
2.05
3.091
0.0019
0.0561
GO:0045182 translation regulator activity
85none
yes
 
before_TSS
15
45
33.3
14.2
2.34
3.682
0.0002
0.0282
GO:0007411 axon guidance
86none
yes
 
after_TSS
14
58
24.1
8.6
2.79
4.205
0
0.0031
GO:0005730
87none
 
yes
before_TSS
14
61
22.9
10.1
2.26
3.33
0.0008
0.0288
GO:0035295 tube development
88none
yes
yes
before_TSS
13
162
8
1.8
4.43
5.974
0
0
GO:0048468 cell development
89none
yes
yes
before_TSS
13
137
9.4
1.8
5.24
6.781
0
0
GO:0030182 neuron differentiation
90none
yes
yes
before_TSS
13
238
5.4
1.8
3.01
4.269
0
0.0071
GO:0000902 cellular morphogenesis
91none
 
yes
before_TSS
13
51
25.4
10.1
2.51
3.646
0.0002
0.0121
GO:0000785
92none
 
 
at_TSS
13
22
59
26.9
2.19
3.406
0.0006
0.0603
GO:0006403 RNA localization
93none
yes
 
at_TSS
12
82
14.6
5.5
2.65
3.638
0.0002
0.0502
GO:0045892 negative regulation of transcription, DNA-dependent
94none
yes
yes
before_TSS
12
226
5.3
1.8
2.93
3.984
0
0.0248
GO:0008283 cell proliferation
95none
yes
 
before_TSS
12
37
32.4
14.2
2.28
3.181
0.0014
0.0596
GO:0035239 tube morphogenesis
96none
 
yes
before_TSS
12
53
22.6
10.1
2.23
3.028
0.0024
0.0901
GO:0016563 transcriptional activator activity
97none
 
yes
after_TSS
12
29
41.3
16
2.57
3.721
0.0001
0.0726
GO:0006364 rRNA processing
98none
yes
yes
before_TSS
12
229
5.2
1.8
2.89
3.932
0
0.0044
GO:0007610 behavior
99none
yes
yes
at_TSS
11
86
12.7
1.9
6.64
7.359
0
0
GO:0008135 translation factor activity, nucleic acid binding
100none
yes
yes
at_TSS
11
90
12.2
1.9
6.34
7.135
0
0
GO:0045182 translation regulator activity
101none
yes
yes
before_TSS
11
107
10.2
1.8
5.68
6.602
0
0
GO:0000904 cellular morphogenesis during differentiation
102none
 
yes
before_TSS
11
34
32.3
10.1
3.19
4.303
0
0.002
GO:0003714 transcription corepressor activity
103none
yes
yes
before_TSS
10
108
9.2
1.8
5.11
5.834
0
0
GO:0048666 neuron development
104none
yes
yes
before_TSS
10
165
6
1.8
3.34
4.124
0
0.0034
GO:0040011 locomotion
105none
yes
yes
before_TSS
10
96
10.4
1.8
5.75
6.351
0
0
GO:0048667 neuron morphogensis during differentiation
106none
yes
yes
before_TSS
10
81
12.3
1.8
6.82
7.137
0
0
GO:0007409 axonogenesis
107none
yes
yes
before_TSS
10
187
5.3
1.8
2.95
3.658
0.0002
0.0155
GO:0007626 locomotory behavior
108none
yes
yes
before_TSS
10
96
10.4
1.8
5.75
6.351
0
0
GO:0031175 neurite morphogenesis
109none
yes
yes
before_TSS
10
162
6.1
1.8
3.41
4.194
0
0.0025
GO:0006928 cell motility
110none
 
yes
before_TSS
10
37
27
10.1
2.67
3.414
0.0006
0.039
GO:0035239 tube morphogenesis
111ADD_LRH
 
 
after_TSS
60
839
7.1
3.8
1.86
5.187
0
0.001
GO:0016043 cell organization and biogenesis
112ADD_LRH
 
 
after_TSS
51
645
7.9
3.8
2.06
5.536
0
0
GO:0006996 organelle organization and biogenesis
113ADD_LRH
 
 
after_TSS
36
427
8.4
3.8
2.19
5.036
0
0.0005
GO:0006259 DNA metabolism
114ADD_LRH
 
 
after_TSS
30
220
13.6
3.8
3.55
7.641
0
0
GO:0051276 chromosome organization and biogenesis
115ADD_LRH
 
 
after_TSS
28
208
13.4
3.8
3.51
7.294
0
0
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
116ADD_LRH
 
 
after_TSS
26
179
14.5
3.8
3.78
7.505
0
0
GO:0006325 establishment and/or maintenance of chromatin architecture
117ADD_LRH
 
 
after_TSS
26
188
13.8
3.8
3.6
7.193
0
0
GO:0006323 DNA packaging
118ADD_LRH
 
 
after_TSS
24
121
19.8
3.8
5.17
9.212
0
0
GO:0006333 chromatin assembly or disassembly
119ADD_LRH
 
 
after_TSS
24
86
27.9
3.8
7.27
11.667
0
0
GO:0006334 nucleosome assembly
120ADD_LRH
 
 
after_TSS
24
123
19.5
3.8
5.08
9.101
0
0
GO:0006461 protein complex assembly
121ADD_LRH
 
 
after_TSS
24
95
25.2
3.8
6.58
10.92
0
0
GO:0031497 chromatin assembly
122ADD_LRH
 
 
after_TSS
23
88
26.1
3.8
6.81
10.935
0
0
GO:0005694
123ADD_LRH
 
 
after_TSS
22
78
28.2
3.8
7.35
11.245
0
0
GO:0000786
124ADD_LRH
yes
 
after_TSS
12
95
12.6
0.5
21.23
15.315
0
0
GO:0031497 chromatin assembly
125ADD_LRH
yes
 
after_TSS
12
220
5.4
0.5
9.16
9.459
0
0
GO:0051276 chromosome organization and biogenesis
126ADD_LRH
yes
 
after_TSS
12
86
13.9
0.5
23.45
16.166
0
0
GO:0006334 nucleosome assembly
127ADD_LRH
yes
 
after_TSS
12
78
15.3
0.5
25.86
17.039
0
0
GO:0000786
128ADD_LRH
yes
 
after_TSS
12
123
9.7
0.5
16.39
13.279
0
0
GO:0006461 protein complex assembly
129ADD_LRH
yes
 
after_TSS
12
179
6.7
0.5
11.26
10.707
0
0
GO:0006325 establishment and/or maintenance of chromatin architecture
130ADD_LRH
yes
 
after_TSS
12
188
6.3
0.5
10.72
10.4
0
0
GO:0006323 DNA packaging
131ADD_LRH
yes
 
after_TSS
12
121
9.9
0.5
16.67
13.401
0
0
GO:0006333 chromatin assembly or disassembly
132ADD_LRH
yes
 
after_TSS
12
208
5.7
0.5
9.69
9.788
0
0
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
133ADD_LRH
yes
 
after_TSS
11
88
12.5
0.5
21.01
14.575
0
0
GO:0005694
134MIT_001NRF1
 
 
at_TSS
13
90
14.4
2.6
5.42
6.972
0
0
GO:0045182 translation regulator activity
135MIT_001NRF1
 
 
at_TSS
13
86
15.1
2.6
5.68
7.203
0
0
GO:0008135 translation factor activity, nucleic acid binding
136MIT_001NRF1
 
 
at_TSS
12
122
9.8
2.6
3.69
4.949
0
0.0018
GO:0000279 M phase
137MIT_001NRF1
 
 
after_TSS
12
188
6.3
0.6
9.53
9.683
0
0
GO:0006323 DNA packaging
138MIT_001NRF1
 
 
after_TSS
12
208
5.7
0.6
8.62
9.099
0
0
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
139MIT_001NRF1
 
 
after_TSS
12
220
5.4
0.6
8.15
8.785
0
0
GO:0051276 chromosome organization and biogenesis
140MIT_001NRF1
 
 
after_TSS
12
179
6.7
0.6
10.01
9.976
0
0
GO:0006325 establishment and/or maintenance of chromatin architecture
141MIT_001NRF1
 
 
after_TSS
11
123
8.9
0.6
13.36
11.311
0
0
GO:0006461 protein complex assembly
142MIT_001NRF1
 
 
after_TSS
11
86
12.7
0.6
19.11
13.835
0
0
GO:0006334 nucleosome assembly
143MIT_001NRF1
 
 
after_TSS
11
121
9
0.6
13.58
11.418
0
0
GO:0006333 chromatin assembly or disassembly
144MIT_001NRF1
 
 
after_TSS
11
78
14.1
0.6
21.07
14.597
0
0
GO:0000786
145MIT_001NRF1
 
 
after_TSS
11
95
11.5
0.6
17.3
13.092
0
0
GO:0031497 chromatin assembly
146MIT_001NRF1
 
 
at_TSS
10
53
18.8
2.6
7.09
7.347
0
0
GO:0003743 translation initiation factor activity
147MIT_003ELK
 
 
at_TSS
39
508
7.6
3.3
2.32
5.631
0
0
GO:0008104 protein localization
148MIT_003ELK
 
 
at_TSS
38
478
7.9
3.3
2.4
5.796
0
0
GO:0046907 intracellular transport
149MIT_003ELK
 
 
at_TSS
37
492
7.5
3.3
2.27
5.339
0
0.0002
GO:0045184 establishment of protein localization
150MIT_003ELK
 
 
at_TSS
37
476
7.7
3.3
2.35
5.563
0
0
GO:0015031 protein transport
151MIT_003ELK
 
 
at_TSS
29
350
8.2
3.3
2.5
5.289
0
0.0004
GO:0006886 intracellular protein transport
152MIT_003ELK
 
 
at_TSS
16
123
13
3.3
3.93
6.05
0
0
GO:0046903 secretion
153MIT_003ELK
 
 
at_TSS
14
101
13.8
3.3
4.19
5.959
0
0
GO:0045045 secretory pathway
154MIT_006SP1
 
 
before_TSS
58
443
13
6.3
2.06
5.934
0
0
GO:0007049 cell cycle
155MIT_006SP1
 
 
before_TSS
22
127
17.3
6.3
2.72
5.101
0
0.0146
GO:0008047 enzyme activator activity
156MIT_006SP1
yes
 
before_TSS
20
308
6.4
2.3
2.75
4.851
0
0.053
GO:0005975 carbohydrate metabolism
157MIT_006SP1
 
 
at_TSS
18
53
33.9
11.6
2.91
5.07
0
0.0034
GO:0003743 translation initiation factor activity
158MIT_006SP1
 
 
after_TSS
12
53
22.6
6.4
3.53
4.833
0
0.0193
GO:0003743 translation initiation factor activity
159MIT_012MYOD
 
 
after_TSS
10
42
23.8
6
3.91
4.815
0
0.0318
GO:0004540 ribonuclease activity
160MIT_018SREBP
 
 
at_TSS
12
78
15.3
0.9
16.77
13.446
0
0
GO:0005764
161MIT_019
 
 
after_TSS
12
88
13.6
3.2
4.19
5.518
0
0
GO:0005694
162MIT_019
 
 
after_TSS
11
95
11.5
3.2
3.56
4.599
0
0.0025
GO:0031497 chromatin assembly
163MIT_019
 
 
after_TSS
11
86
12.7
3.2
3.93
5.01
0
0.0003
GO:0006334 nucleosome assembly
164MIT_019
 
 
at_TSS
11
90
12.2
2.8
4.33
5.411
0
0.0001
GO:0045182 translation regulator activity
165MIT_019
 
 
after_TSS
10
78
12.8
3.2
3.94
4.785
0
0.0011
GO:0000786
166MIT_022
 
 
at_TSS
25
472
5.2
2.1
2.41
4.705
0
0.0219
GO:0009059 macromolecule biosynthesis
167MIT_022
 
 
at_TSS
22
421
5.2
2.1
2.38
4.332
0
0.0912
GO:0006412 protein biosynthesis
168MIT_022
 
 
at_TSS
10
86
11.6
2.1
5.31
6.002
0
0
GO:0008135 translation factor activity, nucleic acid binding
169MIT_022
 
 
at_TSS
10
90
11.1
2.1
5.07
5.804
0
0
GO:0045182 translation regulator activity
170MIT_022
 
 
at_TSS
10
122
8.1
2.1
3.74
4.556
0
0.0125
GO:0000279 M phase
171MIT_024MAZ
 
 
after_TSS
20
128
15.6
5.2
2.98
5.31
0
0.0047
GO:0043037 translation
172MIT_024MAZ
 
 
after_TSS
15
90
16.6
5.2
3.18
4.891
0
0.0086
GO:0045182 translation regulator activity
173MIT_024MAZ
 
 
after_TSS
14
86
16.2
5.2
3.11
4.618
0
0.0334
GO:0008135 translation factor activity, nucleic acid binding
174MIT_024MAZ
yes
 
before_TSS
13
229
5.6
1.4
3.88
5.363
0
0.0035
GO:0007610 behavior
175MIT_030
 
 
at_TSS
18
273
6.5
2
3.23
5.38
0
0.0004
GO:0006396 RNA processing
176MIT_041MEIS
 
yes
after_TSS
10
188
5.3
0.3
13.99
11.091
0
0
GO:0006323 DNA packaging
177MIT_041MEIS
 
yes
after_TSS
10
179
5.5
0.3
14.69
11.404
0
0
GO:0006325 establishment and/or maintenance of chromatin architecture
178MIT_045
 
 
after_TSS
13
121
10.7
3.9
2.74
3.89
0.0001
0.0509
GO:0006333 chromatin assembly or disassembly
179MIT_073LEF
 
 
after_TSS
34
613
5.5
2.7
2.05
4.458
0
0.0893
GO:0005622
180MIT_083HNF3
 
 
before_TSS
12
91
13.1
3.9
3.37
4.584
0
0.0657
GO:0016779 nucleotidyltransferase activity
181MIT_101
 
 
at_TSS
14
205
6.8
2.3
2.96
4.353
0
0.058
GO:0044262 cellular carbohydrate metabolism
182MIT_101
 
 
after_TSS
13
98
13.2
4.3
3.06
4.364
0
0.0788
GO:0008168 methyltransferase activity
183MIT_101
 
 
at_TSS
11
128
8.5
2.3
3.72
4.766
0
0.0073
GO:0043037 translation
184MIT_140
 
 
at_TSS
28
492
5.6
2.8
2.03
3.966
0
0.0717
GO:0045184 establishment of protein localization
185MIT_140
 
 
at_TSS
28
476
5.8
2.8
2.1
4.156
0
0.0368
GO:0015031 protein transport
186MIT_140
 
 
at_TSS
25
350
7.1
2.8
2.55
4.995
0
0.0014
GO:0006886 intracellular protein transport
187MIT_140
 
 
at_TSS
11
120
9.1
2.8
3.27
4.247
0
0.0624
GO:0008565 protein transporter activity
188MIT_152
 
 
before_TSS
11
157
7
1.8
3.7
4.733
0
0.0478
GO:0007167 enzyme linked receptor protein signaling pathway
189TF_AHR
 
 
after_TSS
76
427
17.7
9.8
1.8
5.612
0
0
GO:0006259 DNA metabolism
190TF_AHR
 
 
at_TSS
55
354
15.5
8.3
1.86
4.981
0
0.0007
GO:0003723 RNA binding
191TF_AHR
 
 
at_TSS
47
273
17.2
8.3
2.06
5.375
0
0.0004
GO:0006396 RNA processing
192TF_AHR
 
 
after_TSS
46
220
20.9
9.8
2.12
5.556
0
0
GO:0051276 chromosome organization and biogenesis
193TF_AHR
 
 
after_TSS
44
208
21.1
9.8
2.14
5.519
0
0
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
194TF_AHR
 
 
after_TSS
42
188
22.3
9.8
2.26
5.792
0
0
GO:0006323 DNA packaging
195TF_AHR
 
 
after_TSS
41
179
22.9
9.8
2.32
5.905
0
0
GO:0006325 establishment and/or maintenance of chromatin architecture
196TF_AHR
 
 
after_TSS
34
121
28
9.8
2.85
6.77
0
0
GO:0006333 chromatin assembly or disassembly
197TF_AHR
 
 
after_TSS
32
123
26
9.8
2.64
6.048
0
0
GO:0006461 protein complex assembly
198TF_AHR
yes
 
at_TSS
29
354
8.1
3
2.7
5.762
0
0
GO:0003723 RNA binding
199TF_AHR
 
 
before_TSS
29
149
19.4
8.9
2.17
4.535
0
0.0355
GO:0009892 negative regulation of metabolism
200TF_AHR
 
 
after_TSS
29
95
30.5
9.8
3.09
6.79
0
0
GO:0031497 chromatin assembly
201TF_AHR
 
 
after_TSS
27
88
30.6
9.8
3.11
6.582
0
0
GO:0005694
202TF_AHR
 
 
after_TSS
27
86
31.3
9.8
3.18
6.729
0
0
GO:0006334 nucleosome assembly
203TF_AHR
 
 
before_TSS
26
132
19.6
8.9
2.2
4.36
0
0.0562
GO:0031324 negative regulation of cellular metabolism
204TF_AHR
 
 
after_TSS
24
78
30.7
9.8
3.12
6.22
0
0
GO:0000786
205TF_AHR
 
 
before_TSS
23
115
20
8.9
2.23
4.181
0
0.0696
GO:0016481 negative regulation of transcription
206TF_AHR
 
 
before_TSS
23
121
19
8.9
2.12
3.905
0
0.0331
GO:0006333 chromatin assembly or disassembly
207TF_AHR
yes
 
after_TSS
21
273
7.6
3.1
2.47
4.416
0
0.0289
GO:0006396 RNA processing
208TF_AHR
 
 
at_TSS
18
74
24.3
8.3
2.92
4.994
0
0.0008
GO:0042254 ribosome biogenesis and assembly
209TF_AHR
 
 
at_TSS
18
82
21.9
8.3
2.63
4.479
0
0.0111
GO:0007028 cytoplasm organization and biogenesis
210TF_AHR
 
 
at_TSS
17
67
25.3
8.3
3.04
5.063
0
0.0005
GO:0007046 ribosome biogenesis
211TF_AHR
yes
 
after_TSS
16
154
10.3
3.1
3.34
5.242
0
0.0009
GO:0008380 RNA splicing
212TF_AHR
yes
 
after_TSS
16
189
8.4
3.1
2.72
4.279
0
0.0405
GO:0006397 mRNA processing
213TF_AHR
yes
 
after_TSS
15
149
10
3.1
3.24
4.927
0
0.0027
GO:0000375 RNA splicing, via transesterification reactions
214TF_AHR
 
 
at_TSS
15
58
25.8
8.3
3.1
4.844
0
0.0068
GO:0005730
215TF_AHR
yes
 
after_TSS
15
149
10
3.1
3.24
4.927
0
0.0027
GO:0000398 nuclear mRNA splicing, via spliceosome
216TF_AHR
yes
 
after_TSS
15
149
10
3.1
3.24
4.927
0
0.0027
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
217TF_AHR
 
 
before_TSS
11
34
32.3
8.9
3.62
4.795
0
0.0351
GO:0003714 transcription corepressor activity
218TF_AP2
 
 
before_TSS
91
941
9.6
6
1.6
4.868
0
0.0021
GO:0030528 transcription regulator activity
219TF_AP2
 
 
at_TSS
78
759
10.2
6.2
1.64
4.751
0
0.0437
GO:0005737
220TF_AP2
 
 
at_TSS
45
390
11.5
6.2
1.84
4.399
0
0.0261
GO:0006512 ubiquitin cycle
221TF_AP2
 
 
after_TSS
43
202
21.2
9.8
2.15
5.495
0
0.0001
GO:0016071 mRNA metabolism
222TF_AP2
 
 
after_TSS
39
189
20.6
9.8
2.09
5.009
0
0.0019
GO:0006397 mRNA processing
223TF_AP2
 
 
after_TSS
31
154
20.1
9.8
2.04
4.304
0
0.0453
GO:0008380 RNA splicing
224TF_AP2
 
 
after_TSS
30
149
20.1
9.8
2.04
4.234
0
0.0522
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
225