CisView Mouse (mm6, March 2005)

Main Gene Ontology terms for targets of TF_IRF

No.GO annotation
Total
genes
with GO
Location
Max no. of
genes with
TF_IRF
TF_IRF alone
In pair
with
1GO:0050896 response to stimulus
1020
at_TSS
134
yes
 
2GO:0007275 development
1378
before_TSS
121
yes
 
3GO:0050874 organismal physiological process
881
at_TSS
108
yes
 
4GO:0006952 defense response
463
at_TSS,after_TSS
99
yes
 
5GO:0009607 response to biotic stimulus
483
at_TSS
93
yes
 
6GO:0048513 organ development
852
before_TSS
78
yes
 
7GO:0009653 morphogenesis
811
before_TSS
73
yes
 
8GO:0006955 immune response
379
at_TSS
72
yes
 
9GO:0009605 response to external stimulus
489
at_TSS
65
yes
 
10GO:0009887 organ morphogenesis
674
before_TSS
59
yes
 
11GO:0030154 cell differentiation
538
before_TSS
53
yes
 
12GO:0043207 response to external biotic stimulus
237
at_TSS,after_TSS
52
yes
 
13GO:0009613 response to pest, pathogen or parasite
221
at_TSS,after_TSS
50
yes
 
14GO:0009611 response to wounding
180
at_TSS,after_TSS
45
yes
 
15GO:0048519 negative regulation of biological process
408
before_TSS
42
yes
 
16GO:0043118 negative regulation of physiological process
342
before_TSS
38
yes
 
17GO:0048523 negative regulation of cellular process
375
before_TSS
37
yes
 
18GO:0051243 negative regulation of cellular physiological process
330
before_TSS
35
yes
 
19GO:0006323 DNA packaging
188
before_TSS
32
 
MIT_060FOXO, TF_HMX,
20GO:0007399 nervous system development
301
before_TSS
30
yes
 
21GO:0007600 sensory perception
196
at_TSS
26
yes
 
22GO:0008283 cell proliferation
226
before_TSS
26
yes
 
23GO:0006954 inflammatory response
101
at_TSS,after_TSS
26
yes
 
24GO:0007610 behavior
229
before_TSS
26
yes
 
25GO:0005179 hormone activity
97
after_TSS
25
yes
 
26GO:0004519 endonuclease activity
70
after_TSS
23
yes
 
27GO:0007626 locomotory behavior
187
before_TSS
21
yes
 
28GO:0006928 cell motility
162
before_TSS
20
yes
 
29GO:0040011 locomotion
165
before_TSS
20
yes
 
30GO:0042127 regulation of cell proliferation
139
before_TSS
19
yes
 
31GO:0048468 cell development
162
before_TSS
18
yes
 
32GO:0009790 embryonic development
170
before_TSS
18
yes
 
33GO:0016477 cell migration
141
before_TSS
17
yes
 
34GO:0030182 neuron differentiation
137
before_TSS
16
yes
 
35GO:0050790 regulation of enzyme activity
107
before_TSS
14
 
TF_HFH,
36GO:0006281 DNA repair
133
before_TSS
13
 
TF_CDC5,
37GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
208
before_TSS
13
 
TF_HMX,
38GO:0007517 muscle development
99
before_TSS
13
yes
 
39GO:0006333 chromatin assembly or disassembly
121
before_TSS
12
 
TF_TGIF,
40GO:0006325 establishment and/or maintenance of chromatin architecture
179
before_TSS
12
 
TF_HMX,
41GO:0005125 cytokine activity
173
at_TSS
12
yes
 
42GO:0009792 embryonic development (sensu Metazoa)
85
before_TSS
12
yes
 
43GO:0051239 regulation of organismal physiological process
119
at_TSS
11
yes
 
44GO:0045321 immune cell activation
102
at_TSS
11
yes
 
45GO:0001775 cell activation
103
at_TSS
11
yes
 
46GO:0050776 regulation of immune response
72
at_TSS
10
yes
 
47GO:0031497 chromatin assembly
95
before_TSS
10
 
TF_TGIF,
48GO:0006461 protein complex assembly
123
before_TSS
10
 
TF_HMX,
49GO:0006334 nucleosome assembly
86
before_TSS
10
 
TF_TGIF,
50GO:0046649 lymphocyte activation
94
at_TSS
10
yes
 

Pairs of TF_IRF binding sites with other TFBS

No.TFBS
Location
Total GO-s
Main GO annotation
N pairs for
main GO
Total genes
for main GO
1TF_HMX
before_TSS
4
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
13
208
2TF_TGIF
before_TSS
3
GO:0006333 chromatin assembly or disassembly
12
121
3TF_CDC5
before_TSS
1
GO:0006281 DNA repair
13
133
4TF_HFH
before_TSS
1
GO:0050790 regulation of enzyme activity
14
107
5MIT_060FOXO
before_TSS
1
GO:0006323 DNA packaging
32
188

Details on Gene Ontology terms for targets of TF_IRF

Total number of genes = 12103
No.In pair
with
Multi-
ple
Conser-
ved
Location
Frequency
in list
U-clusters
in list
Genes with TFBS
in list, %
Genes with TFBS
total, %
Ratio
z
p
FDR
GO annotation
1none
 
 
at_TSS
134
1020
13.1
7.7
1.68
6.669
0
0
GO:0050896 response to stimulus
2none
 
yes
before_TSS
121
1378
8.7
5.8
1.5
4.993
0
0
GO:0007275 development
3none
 
 
at_TSS
108
881
12.2
7.7
1.57
5.149
0
0
GO:0050874 organismal physiological process
4none
 
 
after_TSS
99
463
21.3
14.2
1.5
4.487
0
0.0002
GO:0006952 defense response
5none
 
 
at_TSS
93
483
19.2
7.7
2.47
9.603
0
0
GO:0009607 response to biotic stimulus
6none
 
 
at_TSS
91
463
19.6
7.7
2.52
9.721
0
0
GO:0006952 defense response
7none
 
yes
before_TSS
78
852
9.1
5.8
1.57
4.317
0
0.0001
GO:0048513 organ development
8none
 
yes
before_TSS
73
811
9
5.8
1.54
4.011
0
0.0004
GO:0009653 morphogenesis
9none
 
 
at_TSS
72
379
18.9
7.7
2.44
8.279
0
0
GO:0006955 immune response
10none
 
 
at_TSS
65
489
13.2
7.7
1.7
4.641
0
0.0001
GO:0009605 response to external stimulus
11none
 
yes
before_TSS
59
674
8.7
5.8
1.5
3.352
0.0008
0.0036
GO:0009887 organ morphogenesis
12none
 
yes
before_TSS
53
538
9.8
5.8
1.69
4.089
0
0.0012
GO:0030154 cell differentiation
13none
 
 
after_TSS
52
237
21.9
14.2
1.54
3.428
0.0006
0.0111
GO:0043207 response to external biotic stimulus
14none
 
 
after_TSS
50
221
22.6
14.2
1.58
3.601
0.0003
0.0061
GO:0009613 response to pest, pathogen or parasite
15none
 
 
after_TSS
45
180
25
14.2
1.75
4.163
0
0.0038
GO:0009611 response to wounding
16none
 
yes
before_TSS
42
408
10.2
5.8
1.76
3.93
0
0.0028
GO:0048519 negative regulation of biological process
17none
 
 
at_TSS
41
237
17.2
7.7
2.22
5.522
0
0
GO:0043207 response to external biotic stimulus
18none
 
 
at_TSS
39
221
17.6
7.7
2.26
5.523
0
0
GO:0009613 response to pest, pathogen or parasite
19none
 
yes
before_TSS
38
342
11.1
5.8
1.91
4.243
0
0.002
GO:0043118 negative regulation of physiological process
20none
 
yes
before_TSS
37
375
9.8
5.8
1.69
3.403
0.0006
0.0174
GO:0048523 negative regulation of cellular process
21none
 
yes
before_TSS
35
330
10.6
5.8
1.82
3.768
0.0001
0.006
GO:0051243 negative regulation of cellular physiological process
22none
 
yes
before_TSS
30
301
9.9
5.8
1.71
3.115
0.0018
0.012
GO:0007399 nervous system development
23none
 
yes
before_TSS
26
226
11.5
5.8
1.97
3.687
0.0002
0.0207
GO:0008283 cell proliferation
24none
 
 
at_TSS
26
180
14.4
7.7
1.85
3.36
0.0007
0.0285
GO:0009611 response to wounding
25none
 
yes
before_TSS
26
229
11.3
5.8
1.95
3.614
0.0003
0.01
GO:0007610 behavior
26none
 
 
at_TSS
26
196
13.2
7.7
1.7
2.888
0.0038
0.0675
GO:0007600 sensory perception
27none
 
 
after_TSS
26
101
25.7
14.2
1.8
3.323
0.0008
0.0407
GO:0006954 inflammatory response
28none
 
 
after_TSS
25
97
25.7
14.2
1.81
3.264
0.001
0.0148
GO:0005179 hormone activity
29none
 
 
after_TSS
23
70
32.8
14.2
2.3
4.471
0
0.0028
GO:0004519 endonuclease activity
30none
 
yes
after_TSS
21
302
6.9
4.2
1.63
2.362
0.0181
0.0911
GO:0005667
31none
 
yes
before_TSS
21
187
11.2
5.8
1.93
3.187
0.0014
0.0375
GO:0007626 locomotory behavior
32none
 
 
at_TSS
20
101
19.8
7.7
2.54
4.527
0
0.0003
GO:0006954 inflammatory response
33none
 
yes
before_TSS
20
165
12.1
5.8
2.08
3.483
0.0004
0.0164
GO:0040011 locomotion
34none
 
yes
before_TSS
20
162
12.3
5.8
2.12
3.574
0.0003
0.0128
GO:0006928 cell motility
35none
 
yes
before_TSS
19
139
13.6
5.8
2.34
3.978
0
0.0254
GO:0042127 regulation of cell proliferation
36none
 
yes
before_TSS
18
170
10.5
5.8
1.82
2.676
0.0074
0.0779
GO:0009790 embryonic development
37none
 
yes
before_TSS
18
162
11.1
5.8
1.91
2.898
0.0037
0.0509
GO:0048468 cell development
38none
 
yes
before_TSS
17
141
12
5.8
2.07
3.184
0.0014
0.0483
GO:0016477 cell migration
39none
 
yes
before_TSS
16
137
11.6
5.8
2
2.948
0.0031
0.0354
GO:0030182 neuron differentiation
40none
 
 
at_TSS
15
88
17
7.7
2.19
3.254
0.0011
0.0231
GO:0005694
41none
 
yes
before_TSS
13
99
13.1
5.8
2.25
3.122
0.0017
0.0657
GO:0007517 muscle development
42none
 
 
at_TSS
13
78
16.6
7.7
2.14
2.937
0.0033
0.0638
GO:0000786
43none
 
yes
at_TSS
12
173
6.9
2.6
2.59
3.495
0.0004
0.0433
GO:0005125 cytokine activity
44none
 
yes
before_TSS
12
85
14.1
5.8
2.42
3.281
0.001
0.0344
GO:0009792 embryonic development (sensu Metazoa)
45none
 
 
at_TSS
12
60
20
7.7
2.56
3.54
0.0004
0.0488
GO:0009897
46none
 
yes
at_TSS
11
103
10.6
2.6
3.98
5.053
0
0.0001
GO:0001775 cell activation
47none
 
yes
at_TSS
11
102
10.7
2.6
4.02
5.094
0
0.0001
GO:0045321 immune cell activation
48none
 
yes
at_TSS
11
119
9.2
2.6
3.45
4.459
0
0.0015
GO:0051239 regulation of organismal physiological process
49none
 
yes
at_TSS
10
72
13.8
2.6
5.18
5.911
0
0
GO:0050776 regulation of immune response
50none
 
yes
at_TSS
10
94
10.6
2.6
3.97
4.8
0
0.0005
GO:0046649 lymphocyte activation
51MIT_060FOXO
 
 
before_TSS
32
188
17
9.2
1.84
3.736
0.0001
0.0727
GO:0006323 DNA packaging
52TF_ATF1
 
 
before_TSS
11
88
12.5
4.5
2.77
3.63
0.0002
0.0956
GO:0005694
53TF_CDC5
 
 
before_TSS
13
133
9.7
2.7
3.61
5.058
0
0.0091
GO:0006281 DNA repair
54TF_HFH
 
 
before_TSS
14
107
13
4.1
3.16
4.665
0
0.0444
GO:0050790 regulation of enzyme activity
55TF_HMX
 
 
before_TSS
13
208
6.2
2.3
2.64
3.722
0.0001
0.0821
GO:0007001 chromosome organization and biogenesis (sensu Eukaryota)
56TF_HMX
 
 
before_TSS
12
179
6.7
2.3
2.83
3.851
0.0001
0.0503
GO:0006325 establishment and/or maintenance of chromatin architecture
57TF_HMX
 
 
before_TSS
12
188
6.3
2.3
2.7
3.657
0.0002
0.0967
GO:0006323 DNA packaging
58TF_HMX
 
 
before_TSS
10
123
8.1
2.3
3.44
4.232
0
0.0099
GO:0006461 protein complex assembly
59TF_TGIF
 
 
before_TSS
12
121
9.9
2.7
3.55
4.78
0
0.0007
GO:0006333 chromatin assembly or disassembly
60TF_TGIF
 
 
before_TSS
10
95
10.5
2.7
3.76
4.592
0
0.0016
GO:0031497 chromatin assembly
61TF_TGIF
 
 
before_TSS
10
86
11.6
2.7
4.16
4.99
0
0.0002
GO:0006334 nucleosome assembly