CisView Mouse (mm6, March 2005)

Main Gene Ontology terms for targets of TF_MEF2

No.GO annotation
Total
genes
with GO
Location
Max no. of
genes with
TF_MEF2
TF_MEF2 alone
In pair
with
1GO:0048513 organ development
852
before_TSS
74
yes
 
2GO:0009887 organ morphogenesis
674
before_TSS
57
yes
 
3GO:0009607 response to biotic stimulus
483
after_TSS
56
yes
 
4GO:0006952 defense response
463
after_TSS
54
yes
 
5GO:0030154 cell differentiation
538
before_TSS
41
yes
 
6GO:0048519 negative regulation of biological process
408
before_TSS
33
yes
 
7GO:0048523 negative regulation of cellular process
375
before_TSS
32
yes
 
8GO:0005102 receptor binding
406
at_TSS
30
yes
 
9GO:0043118 negative regulation of physiological process
342
before_TSS
30
yes
 
10GO:0051243 negative regulation of cellular physiological process
330
before_TSS
30
yes
 
11GO:0043207 response to external biotic stimulus
237
after_TSS
30
yes
 
12GO:0007399 nervous system development
301
before_TSS
29
yes
 
13GO:0004857 enzyme inhibitor activity
155
after_TSS
22
yes
 
14GO:0004866 endopeptidase inhibitor activity
112
after_TSS
17
yes
 
15GO:0030414 protease inhibitor activity
112
after_TSS
17
yes
 
16GO:0004497 monooxygenase activity
90
after_TSS
17
yes
 
17GO:0006325 establishment and/or maintenance of chromatin architecture
179
at_TSS
16
yes
 
18GO:0009892 negative regulation of metabolism
149
before_TSS
16
yes
 
19GO:0007517 muscle development
99
before_TSS
15
yes
 
20GO:0031324 negative regulation of cellular metabolism
132
before_TSS
14
yes
 
21GO:0006333 chromatin assembly or disassembly
121
at_TSS
13
yes
 
22GO:0016481 negative regulation of transcription
115
before_TSS
13
yes
 
23GO:0006461 protein complex assembly
123
at_TSS
13
yes
 
24GO:0007389 pattern specification
128
before_TSS
13
yes
 
25GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
121
before_TSS
13
yes
 
26GO:0007156 homophilic cell adhesion
76
after_TSS
13
yes
 
27GO:0004867 serine-type endopeptidase inhibitor activity
77
after_TSS
13
yes
 
28GO:0006917 induction of apoptosis
65
before_TSS
12
yes
 
29GO:0031497 chromatin assembly
95
at_TSS
12
yes
 
30GO:0006334 nucleosome assembly
86
at_TSS
12
yes
 
31GO:0007507 heart development
66
before_TSS
12
yes
 
32GO:0042127 regulation of cell proliferation
139
before_TSS
12
 
TF_SREBP,
33GO:0012502 induction of programmed cell death
65
before_TSS
12
yes
 
34GO:0016779 nucleotidyltransferase activity
91
before_TSS
11
 
TF_RFX1,

Pairs of TF_MEF2 binding sites with other TFBS

No.TFBS
Location
Total GO-s
Main GO annotation
N pairs for
main GO
Total genes
for main GO
1TF_SREBP
before_TSS
1
GO:0042127 regulation of cell proliferation
12
139
2TF_RFX1
before_TSS
1
GO:0016779 nucleotidyltransferase activity
11
91

Details on Gene Ontology terms for targets of TF_MEF2

Total number of genes = 12103
No.In pair
with
Multi-
ple
Conser-
ved
Location
Frequency
in list
U-clusters
in list
Genes with TFBS
in list, %
Genes with TFBS
total, %
Ratio
z
p
FDR
GO annotation
1none
 
yes
before_TSS
74
852
8.6
5
1.72
5.059
0
0
GO:0048513 organ development
2none
 
yes
before_TSS
57
674
8.4
5
1.68
4.185
0
0.0002
GO:0009887 organ morphogenesis
3none
 
 
after_TSS
56
483
11.5
7.7
1.5
3.275
0.001
0.0077
GO:0009607 response to biotic stimulus
4none
 
 
after_TSS
54
463
11.6
7.7
1.51
3.26
0.0011
0.0081
GO:0006952 defense response
5none
 
yes
before_TSS
41
538
7.6
5
1.51
2.81
0.0049
0.0362
GO:0030154 cell differentiation
6none
 
yes
before_TSS
33
408
8
5
1.6
2.872
0.004
0.0533
GO:0048519 negative regulation of biological process
7none
 
yes
before_TSS
32
375
8.5
5
1.69
3.15
0.0016
0.0331
GO:0048523 negative regulation of cellular process
8none
 
yes
before_TSS
32
302
10.5
5
2.1
4.479
0
0
GO:0005667
9none
 
yes
before_TSS
30
342
8.7
5
1.74
3.209
0.0013
0.0256
GO:0043118 negative regulation of physiological process
10none
 
yes
before_TSS
30
330
9
5
1.8
3.419
0.0006
0.0176
GO:0051243 negative regulation of cellular physiological process
11none
 
 
after_TSS
30
237
12.6
7.7
1.64
2.891
0.0038
0.0342
GO:0043207 response to external biotic stimulus
12none
 
 
at_TSS
30
406
7.3
4.5
1.62
2.788
0.0053
0.0843
GO:0005102 receptor binding
13none
 
yes
before_TSS
29
301
9.6
5
1.91
3.699
0.0002
0.0026
GO:0007399 nervous system development
14none
 
 
after_TSS
22
155
14.1
7.7
1.84
3.051
0.0022
0.0556
GO:0004857 enzyme inhibitor activity
15none
 
 
after_TSS
17
112
15.1
7.7
1.97
2.982
0.0028
0.0499
GO:0004866 endopeptidase inhibitor activity
16none
 
 
after_TSS
17
90
18.8
7.7
2.45
3.996
0
0.0026
GO:0004497 monooxygenase activity
17none
 
 
after_TSS
17
112
15.1
7.7
1.97
2.982
0.0028
0.0499
GO:0030414 protease inhibitor activity
18none
 
 
at_TSS
16
179
8.9
4.5
1.96
2.835
0.0045
0.0729
GO:0006325 establishment and/or maintenance of chromatin architecture
19none
 
yes
before_TSS
16
149
10.7
5
2.13
3.206
0.0013
0.0289
GO:0009892 negative regulation of metabolism
20none
 
yes
before_TSS
15
99
15.1
5
3.01
4.624
0
0.0004
GO:0007517 muscle development
21none
 
 
after_TSS
15
60
25
7.7
3.24
5.038
0
0.0001
GO:0009897
22none
 
yes
before_TSS
14
132
10.6
5
2.1
2.945
0.0032
0.0622
GO:0031324 negative regulation of cellular metabolism
23none
 
 
after_TSS
13
77
16.8
7.7
2.19
3.031
0.0024
0.0637
GO:0004867 serine-type endopeptidase inhibitor activity
24none
 
 
after_TSS
13
76
17.1
7.7
2.22
3.084
0.002
0.0747
GO:0007156 homophilic cell adhesion
25none
 
yes
before_TSS
13
121
10.7
5
2.13
2.888
0.0038
0.0545
GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism
26none
 
yes
before_TSS
13
115
11.3
5
2.24
3.091
0.0019
0.0331
GO:0016481 negative regulation of transcription
27none
 
 
at_TSS
13
123
10.5
4.5
2.32
3.217
0.0012
0.0263
GO:0006461 protein complex assembly
28none
 
yes
before_TSS
13
128
10.1
5
2.01
2.666
0.0076
0.0425
GO:0007389 pattern specification
29none
 
 
at_TSS
13
121
10.7
4.5
2.35
3.283
0.001
0.015
GO:0006333 chromatin assembly or disassembly
30none
 
yes
before_TSS
12
66
18.1
5
3.61
4.9
0
0.0003
GO:0007507 heart development
31none
 
 
at_TSS
12
86
13.9
4.5
3.06
4.196
0
0.0005
GO:0006334 nucleosome assembly
32none
yes
 
before_TSS
12
65
18.4
6.5
2.83
3.91
0
0.0337
GO:0006917 induction of apoptosis
33none
yes
 
before_TSS
12
65
18.4
6.5
2.83
3.91
0
0.0337
GO:0012502 induction of programmed cell death
34none
 
 
at_TSS
12
95
12.6
4.5
2.77
3.792
0.0001
0.0028
GO:0031497 chromatin assembly
35none
 
 
at_TSS
11
78
14.1
4.5
3.09
4.059
0
0.001
GO:0000786
36none
 
 
at_TSS
10
88
11.3
4.5
2.49
3.076
0.002
0.0383
GO:0005694
37TF_RFX1
 
 
before_TSS
11
91
12
2.9
4.15
5.23
0
0.0073
GO:0016779 nucleotidyltransferase activity
38TF_SREBP
 
 
before_TSS
12
139
8.6
2.5
3.42
4.624
0
0.0542
GO:0042127 regulation of cell proliferation