CisView Mouse (mm6, March 2005)

Main Gene Ontology terms for targets of TF_SREBP

No.GO annotation
Total
genes
with GO
Location
Max no. of
genes with
TF_SREBP
TF_SREBP alone
In pair
with
1GO:0007275 development
1378
at_TSS
119
yes
 
2GO:0048513 organ development
852
at_TSS,before_TSS
109
yes
 
3GO:0009653 morphogenesis
811
at_TSS,before_TSS
100
yes
 
4GO:0009887 organ morphogenesis
674
at_TSS,before_TSS
85
yes
 
5GO:0003700 transcription factor activity
719
at_TSS,before_TSS
84
yes
 
6GO:0030528 transcription regulator activity
941
at_TSS
71
yes
 
7GO:0030154 cell differentiation
538
at_TSS,before_TSS
47
yes
TF_MAZR,
8GO:0048523 negative regulation of cellular process
375
before_TSS
40
yes
 
9GO:0007399 nervous system development
301
before_TSS
40
yes
 
10GO:0043118 negative regulation of physiological process
342
before_TSS
38
yes
 
11GO:0051243 negative regulation of cellular physiological process
330
before_TSS
37
yes
 
12GO:0006259 DNA metabolism
427
before_TSS
37
 
MIT_006SP1,
13GO:0030695 GTPase regulator activity
178
after_TSS
34
yes
TF_AHR, TF_SP1,
14GO:0019752 carboxylic acid metabolism
350
before_TSS
30
 
TF_STAF, MIT_140, TF_HNF3,
15GO:0006082 organic acid metabolism
350
before_TSS
30
 
TF_STAF, MIT_140, TF_HNF3,
16GO:0007610 behavior
229
before_TSS
28
yes
 
17GO:0008047 enzyme activator activity
127
after_TSS
27
yes
 
18GO:0007389 pattern specification
128
before_TSS
26
yes
TF_SREBP, TF_MAZR,
19GO:0007626 locomotory behavior
187
before_TSS
24
yes
TF_HTF,
20GO:0009790 embryonic development
170
before_TSS,after_TSS
24
yes
TF_AP2,
21GO:0006812 cation transport
401
at_TSS
23
 
TF_SP1,
22GO:0005083 small GTPase regulator activity
110
after_TSS
23
yes
 
23GO:0040011 locomotion
165
before_TSS
22
yes
TF_HTF,
24GO:0006928 cell motility
162
before_TSS
22
yes
 
25GO:0006807 nitrogen compound metabolism
268
before_TSS
21
 
TF_STAF, TF_AP4,
26GO:0005096 GTPase activator activity
93
after_TSS
20
yes
 
27GO:0016477 cell migration
141
before_TSS
20
yes
 
28GO:0009308 amine metabolism
252
before_TSS
20
 
TF_STAF,
29GO:0046649 lymphocyte activation
94
before_TSS
19
yes
 
30GO:0006519 amino acid and derivative metabolism
219
before_TSS
18
 
TF_STAF,
31GO:0006520 amino acid metabolism
185
before_TSS
17
 
TF_STAF,
32GO:0007517 muscle development
99
at_TSS,before_TSS
17
yes
MIT_015AP4,
33GO:0005125 cytokine activity
173
before_TSS
16
 
TF_E47,
34GO:0008083 growth factor activity
121
at_TSS
15
yes
 
35GO:0035295 tube development
61
before_TSS
15
yes
TF_MAZR,
36GO:0007507 heart development
66
before_TSS
13
yes
 
37GO:0048514 blood vessel morphogenesis
75
before_TSS
13
yes
 
38GO:0006869 lipid transport
45
before_TSS
12
yes
 
39GO:0042127 regulation of cell proliferation
139
before_TSS
12
 
TF_MEF2,
40GO:0000902 cellular morphogenesis
238
before_TSS
12
 
TF_RREB,
41GO:0008134 transcription factor binding
110
before_TSS
12
 
TF_STAT, TF_GFI, TF_LYF,
42GO:0048598 embryonic morphogenesis
62
before_TSS
12
yes
TF_AHR,
43GO:0006813 potassium ion transport
135
at_TSS,before_TSS
11
 
TF_HSF, TF_SP1,
44GO:0042157 lipoprotein metabolism
38
after_TSS
11
 
TF_SP1,
45GO:0042113 B cell activation
40
before_TSS
11
yes
 
46GO:0046873 metal ion transporter activity
67
after_TSS
11
yes
 
47GO:0015077 monovalent inorganic cation transporter activity
138
after_TSS
11
 
TF_HNF4,
48GO:0050795 regulation of behavior
38
before_TSS
10
yes
 
49GO:0040012 regulation of locomotion
37
before_TSS
10
yes
 
50GO:0016853 isomerase activity
118
before_TSS
10
 
TF_POU6F,
51GO:0031098 stress-activated protein kinase signaling pathway
25
at_TSS
10
yes
 
52GO:0051336 regulation of hydrolase activity
46
at_TSS
10
 
TF_SP1,
53GO:0051270 regulation of cell motility
35
before_TSS
10
yes
 
54GO:0001525 angiogenesis
66
at_TSS
10
yes
 
55GO:0007254 JNK cascade
25
at_TSS
10
yes
 
56GO:0001655 urogenital system development
30
after_TSS
10
yes
 
57GO:0035239 tube morphogenesis
37
before_TSS
10
yes
 

Pairs of TF_SREBP binding sites with other TFBS

No.TFBS
Location
Total GO-s
Main GO annotation
N pairs for
main GO
Total genes
for main GO
1TF_STAF
before_TSS
6
GO:0019752 carboxylic acid metabolism
23
350
2TF_SP1
at_TSS,after_TSS
5
GO:0030695 GTPase regulator activity
27
178
3TF_MAZR
before_TSS
3
GO:0030154 cell differentiation
47
538
4TF_HNF3
before_TSS
2
GO:0019752 carboxylic acid metabolism
30
350
5TF_AHR
before_TSS,after_TSS
2
GO:0030695 GTPase regulator activity
25
178
6TF_HTF
before_TSS
2
GO:0007626 locomotory behavior
23
187
7MIT_140
before_TSS
2
GO:0019752 carboxylic acid metabolism
25
350
8TF_STAT
before_TSS
1
GO:0008134 transcription factor binding
12
110
9TF_HSF
before_TSS
1
GO:0006813 potassium ion transport
11
135
10TF_SREBP
before_TSS
1
GO:0007389 pattern specification
11
128
11TF_RREB
before_TSS
1
GO:0000902 cellular morphogenesis
12
238
12TF_LYF
before_TSS
1
GO:0008134 transcription factor binding
11
110
13MIT_006SP1
before_TSS
1
GO:0006259 DNA metabolism
37
427
14TF_GFI
before_TSS
1
GO:0008134 transcription factor binding
11
110
15TF_MEF2
before_TSS
1
GO:0042127 regulation of cell proliferation
12
139
16TF_POU6F
before_TSS
1
GO:0016853 isomerase activity
10
118
17TF_E47
before_TSS
1
GO:0005125 cytokine activity
16
173
18MIT_015AP4
before_TSS
1
GO:0007517 muscle development
13
99
19TF_AP2
after_TSS
1
GO:0009790 embryonic development
11
170
20TF_HNF4
after_TSS
1
GO:0015077 monovalent inorganic cation transporter activity
11
138
21TF_AP4
before_TSS
1
GO:0006807 nitrogen compound metabolism
19
268

Details on Gene Ontology terms for targets of TF_SREBP

Total number of genes = 12103
No.In pair
with
Multi-
ple
Conser-
ved
Location
Frequency
in list
U-clusters
in list
Genes with TFBS
in list, %
Genes with TFBS
total, %
Ratio
z
p
FDR
GO annotation
1none
 
yes
at_TSS
119
1378
8.6
4.9
1.72
6.581
0
0
GO:0007275 development
2none
 
yes
before_TSS
109
852
12.7
7
1.81
6.782
0
0
GO:0048513 organ development
3none
 
yes
before_TSS
100
811
12.3
7
1.74
6.071
0
0
GO:0009653 morphogenesis
4none
 
yes
before_TSS
85
674
12.6
7
1.78
5.795
0
0
GO:0009887 organ morphogenesis
5none
 
yes
before_TSS
84
719
11.6
7
1.65
4.994
0
0
GO:0003700 transcription factor activity
6none
 
yes
at_TSS
81
852
9.5
4.9
1.9
6.262
0
0
GO:0048513 organ development
7none
 
yes
at_TSS
76
811
9.3
4.9
1.87
5.915
0
0
GO:0009653 morphogenesis
8none
 
yes
at_TSS
71
941
7.5
4.9
1.5
3.732
0.0001
0.0012
GO:0030528 transcription regulator activity
9none
 
yes
at_TSS
63
674
9.3
4.9
1.86
5.33
0
0
GO:0009887 organ morphogenesis
10none
 
yes
at_TSS
59
719
8.2
4.9
1.64
4.068
0
0.0004
GO:0003700 transcription factor activity
11none
 
yes
at_TSS
45
538
8.3
4.9
1.67
3.664
0.0002
0.005
GO:0030154 cell differentiation
12none
 
yes
before_TSS
43
302
14.2
7
2.01
4.935
0
0
GO:0005667
13none
 
yes
before_TSS
40
375
10.6
7
1.51
2.773
0.0055
0.0616
GO:0048523 negative regulation of cellular process
14none
 
yes
before_TSS
40
301
13.2
7
1.88
4.275
0
0.0003
GO:0007399 nervous system development
15none
 
yes
before_TSS
38
342
11.1
7
1.57
2.97
0.0029
0.0473
GO:0043118 negative regulation of physiological process
16none
 
yes
before_TSS
37
330
11.2
7
1.58
2.989
0.0027
0.0426
GO:0051243 negative regulation of cellular physiological process
17none
 
yes
after_TSS
34
178
19.1
9.6
1.98
4.323
0
0.0056
GO:0030695 GTPase regulator activity
18none
 
yes
before_TSS
28
229
12.2
7
1.73
3.084
0.002
0.0325
GO:0007610 behavior
19none
 
yes
at_TSS
27
302
8.9
4.9
1.78
3.183
0.0014
0.0118
GO:0005667
20none
 
yes
after_TSS
27
127
21.2
9.6
2.21
4.473
0
0.0028
GO:0008047 enzyme activator activity
21none
yes
 
before_TSS
26
128
20.3
9.2
2.18
4.325
0
0.0006
GO:0007389 pattern specification
22none
 
yes
before_TSS
25
128
19.5
7
2.76
5.54
0
0
GO:0007389 pattern specification
23none
 
yes
before_TSS
24
170
14.1
7
2
3.62
0.0002
0.0063
GO:0009790 embryonic development
24none
 
yes
before_TSS
24
187
12.8
7
1.81
3.109
0.0018
0.0381
GO:0007626 locomotory behavior
25none
 
yes
after_TSS
23
110
20.9
9.6
2.17
4.035
0
0.0199
GO:0005083 small GTPase regulator activity
26none
 
yes
before_TSS
22
165
13.3
7
1.88
3.17
0.0015
0.0265
GO:0040011 locomotion
27none
 
yes
before_TSS
22
162
13.5
7
1.92
3.264
0.001
0.0251
GO:0006928 cell motility
28none
 
yes
before_TSS
20
141
14.1
7
2.01
3.324
0.0008
0.0405
GO:0016477 cell migration
29none
 
yes
after_TSS
20
93
21.5
9.6
2.23
3.903
0
0.0347
GO:0005096 GTPase activator activity
30none
yes
 
before_TSS
19
94
20.2
9.2
2.17
3.667
0.0002
0.0898
GO:0046649 lymphocyte activation
31none
 
yes
before_TSS
17
99
17.1
7
2.43
3.946
0
0.0058
GO:0007517 muscle development
32none
 
yes
at_TSS
15
121
12.3
4.9
2.47
3.752
0.0001
0.0128
GO:0008083 growth factor activity
33none
 
yes
before_TSS
15
61
24.5
7
3.48
5.36
0
0
GO:0035295 tube development
34none
 
yes
before_TSS
13
66
19.6
7
2.79
4.02
0
0.0106
GO:0007507 heart development
35none
 
yes
before_TSS
13
75
17.3
7
2.45
3.486
0.0004
0.0897
GO:0048514 blood vessel morphogenesis
36none
yes
 
before_TSS
12
45
26.6
9.2
2.87
4.027
0
0.0206
GO:0006869 lipid transport
37none
 
yes
at_TSS
12
99
12.1
4.9
2.42
3.265
0.001
0.0445
GO:0007517 muscle development
38none
 
yes
before_TSS
11
62
17.7
7
2.51
3.293
0.0009
0.0302
GO:0048598 embryonic morphogenesis
39none
yes
 
before_TSS
11
40
27.5
9.2
2.96
3.978
0
0.0254
GO:0042113 B cell activation
40none
yes
 
after_TSS
11
67
16.4
5.3
3.04
4.01
0
0.0055
GO:0046873 metal ion transporter activity
41none
 
yes
before_TSS
11
51
21.5
7
3.05
4.055
0
0.0183
GO:0045202
42none
 
yes
after_TSS
10
30
33.3
9.6
3.46
4.411
0
0.0037
GO:0001655 urogenital system development
43none
 
yes
before_TSS
10
37
27
7
3.83
4.75
0
0.0007
GO:0040012 regulation of locomotion
44none
 
yes
before_TSS
10
35
28.5
7
4.04
4.977
0
0.0002
GO:0051270 regulation of cell motility
45none
 
yes
at_TSS
10
66
15.1
4.9
3.03
3.795
0.0001
0.054
GO:0001525 angiogenesis
46none
 
yes
before_TSS
10
38
26.3
7
3.72
4.643
0
0.0012
GO:0050795 regulation of behavior
47none
yes
 
before_TSS
10
37
27
9.2
2.91
3.726
0.0001
0.0142
GO:0035239 tube morphogenesis
48none
 
 
at_TSS
10
25
40
14
2.84
3.73
0.0001
0.07
GO:0007254 JNK cascade
49none
 
 
at_TSS
10
25
40
14
2.84
3.73
0.0001
0.07
GO:0031098 stress-activated protein kinase signaling pathway
50MIT_006SP1
 
 
before_TSS
37
427
8.6
4.1
2.07
4.713
0
0.0029
GO:0006259 DNA metabolism
51MIT_015AP4
 
 
before_TSS
13
99
13.1
3.7
3.5
4.931
0
0.0353
GO:0007517 muscle development
52MIT_140
 
 
before_TSS
25
350
7.1
2.7
2.58
5.062
0
0.0044
GO:0019752 carboxylic acid metabolism
53MIT_140
 
 
before_TSS
25
350
7.1
2.7
2.58
5.062
0
0.0044
GO:0006082 organic acid metabolism
54TF_AHR
 
 
after_TSS
25
178
14
6.2
2.26
4.367
0
0.0907
GO:0030695 GTPase regulator activity
55TF_AHR
 
 
before_TSS
12
62
19.3
5.8
3.28
4.513
0
0.0306
GO:0048598 embryonic morphogenesis
56TF_AP2
 
yes
after_TSS
11
170
6.4
1.4
4.5
5.551
0
0.0012
GO:0009790 embryonic development
57TF_AP4
 
 
before_TSS
19
268
7
2.7
2.62
4.479
0
0.054
GO:0006807 nitrogen compound metabolism
58TF_E47
 
 
before_TSS
16
173
9.2
3.2
2.84
4.485
0
0.0787
GO:0005125 cytokine activity
59TF_FOXD
 
 
before_TSS
10
60
16.6
3.4
4.8
5.598
0
0.0009
GO:0009897
60TF_GFI
 
 
before_TSS
11
110
10
2.8
3.47
4.491
0
0.0765
GO:0008134 transcription factor binding
61TF_HNF3
 
 
before_TSS
30
350
8.5
4
2.13
4.393
0
0.0402
GO:0019752 carboxylic acid metabolism
62TF_HNF3
 
 
before_TSS
30
350
8.5
4
2.13
4.393
0
0.0402
GO:0006082 organic acid metabolism
63TF_HNF3
 
 
before_TSS
10
60
16.6
4
4.14
4.995
0
0.0127
GO:0009897
64TF_HNF4
 
 
after_TSS
11
138
7.9
2.2
3.61
4.637
0
0.0169
GO:0015077 monovalent inorganic cation transporter activity
65TF_HSF
 
 
before_TSS
11
135
8.1
2.2
3.59
4.621
0
0.033
GO:0006813 potassium ion transport
66TF_HTF
 
 
before_TSS
23
187
12.2
5.1
2.38
4.46
0
0.0442
GO:0007626 locomotory behavior
67TF_HTF
 
 
before_TSS
22
165
13.3
5.1
2.59
4.791
0
0.0717
GO:0040011 locomotion
68TF_LYF
 
 
before_TSS
11
110
10
2.7
3.64
4.68
0
0.0619
GO:0008134 transcription factor binding
69TF_MAZR
 
 
before_TSS
47
538
8.7
4.8
1.79
4.267
0
0.0658
GO:0030154 cell differentiation
70TF_MAZR
 
 
before_TSS
20
128
15.6
4.8
3.21
5.686
0
0.0001
GO:0007389 pattern specification
71TF_MAZR
 
 
before_TSS
14
61
22.9
4.8
4.71
6.58
0
0
GO:0035295 tube development
72TF_MEF2
 
 
before_TSS
12
139
8.6
2.5
3.42
4.624
0
0.0542
GO:0042127 regulation of cell proliferation
73TF_POU6F
 
 
before_TSS
10
118
8.4
2
4.16
4.983
0
0.0135
GO:0016853 isomerase activity
74TF_RREB
 
 
before_TSS
12
238
5
1.3
3.81
5.074
0
0.0168
GO:0000902 cellular morphogenesis
75TF_SP1
 
 
after_TSS
27
178
15.1
6.5
2.3
4.665
0
0.0444
GO:0030695 GTPase regulator activity
76TF_SP1
yes
 
at_TSS
23
401
5.7
2.2
2.57
4.832
0
0.0584
GO:0006812 cation transport
77TF_SP1
 
 
after_TSS
11
38
28.9
6.5
4.4
5.577
0
0.001
GO:0042157 lipoprotein metabolism
78TF_SP1
yes
 
at_TSS
11
135
8.1
2.2
3.65
4.681
0
0.0616
GO:0006813 potassium ion transport
79TF_SP1
 
 
at_TSS
10
46
21.7
5.6
3.85
4.739
0
0.0928
GO:0051336 regulation of hydrolase activity
80TF_SREBP
 
 
before_TSS
11
128
8.5
2.5
3.35
4.342
0
0.0554
GO:0007389 pattern specification
81TF_STAF
 
 
before_TSS
23
350
6.5
2.8
2.33
4.322
0
0.0514
GO:0019752 carboxylic acid metabolism
82TF_STAF
 
 
before_TSS
23
350
6.5
2.8
2.33
4.322
0
0.0514
GO:0006082 organic acid metabolism
83TF_STAF
 
 
before_TSS
21
268
7.8
2.8
2.78
5.035
0
0.0103
GO:0006807 nitrogen compound metabolism
84TF_STAF
 
 
before_TSS
20
252
7.9
2.8
2.82
4.977
0
0.0093
GO:0009308 amine metabolism
85TF_STAF
 
 
before_TSS
18
219
8.2
2.8
2.92
4.889
0
0.0109
GO:0006519 amino acid and derivative metabolism
86TF_STAF
 
 
before_TSS
17
185
9.1
2.8
3.27
5.292
0
0.0026
GO:0006520 amino acid metabolism
87TF_STAT
 
 
before_TSS
12
110
10.9
3.3
3.3
4.481
0
0.0642
GO:0008134 transcription factor binding