TFBS = ADD

CisView: Mouse (mm9, Jul 2007)

Transcription factor binding site ADD_AR

Source: Nelson CC, Hendy SC, Shukin RJ, Cheng H, Bruchovsky N, Koop BF, Rennie PS. 1999. Determinants of DNA sequence specificity of the androgen, progesterone, and glucocorticoid receptors: evidence for differential steroid receptor response elements. Mol Endocrinol. 13:2090-107.
TF group: AR TFBS class: HR = Hormone receptor Code: 2.1.1
Pattern = RGTACABNGTGTTCT (core elements are bold) Class: AR Allowed mismatch: 0.2 Palindrome
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Position weight matrix:

position A C G T
1 15 1 29 6
2 1 1 45 4
3 11 5 11 24
4 45 2 0 4
5 1 50 0 0
6 34 0 16 1
7 8 14 11 18
8 12 11 12 16
9 2 4 33 12
10 0 0 0 51
11 0 0 51 0
12 0 0 0 51
13 0 0 0 51
14 0 51 0 0
15 0 0 0 51

Genes (trans-elements):

U-cluster Symbol Annotation
U020040 Ar androgen receptor

GO terms:
GO:0009987 cellular process
GO:0001701 in utero embryonic development
GO:0004872 receptor activity
GO:0004882 androgen receptor activity
GO:0030521 androgen receptor signaling pathway
GO:0019102 male somatic sex determination
GO:0008584 male gonad development
GO:0008270 zinc ion binding
GO:0003707 steroid hormone receptor activity
GO:0046872 metal ion binding
GO:0043565 sequence-specific DNA binding
GO:0005496 steroid binding
GO:0008289 lipid binding

Protein domains:
IPR001628 Zinc finger, nuclear hormone receptor-type
IPR008626 GAL11 transcriptional regulator
IPR007738 Homeobox prospero-like
IPR001103 Androgen receptor
IPR000536 Nuclear hormone receptor, ligand-binding, core

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

position	A	C	G	T
1	15	1	29	6
2	1	1	45	4
3	11	5	11	24
4	45	2	0	4
5	1	50	0	0
6	34	0	16	1
7	8	14	11	18
8	12	11	12	16
9	2	4	33	12
10	0	0	0	51
11	0	0	51	0
12	0	0	0	51
13	0	0	0	51
14	0	51	0	0
15	0	0	0	51

Legend