CisView: Mouse (mm9, Jul 2007)

Transcription factor binding site ADD_FXRDR1

Source: Laffitte BA, Kast HR, Nguyen CM, Zavacki AM, Moore DD, Edwards PA. 2000. Identification of the DNA binding specificity and potential target genes for the farnesoid X-activated receptor. J Biol Chem. 275:10638-47.
TF group: FXR       TFBS class: HR = Hormone receptor       Code: 2.1.2.8.4
Pattern = AGSTCANAGGTTA (used as matrix, core elements are bold)     Class: FXR     Allowed mismatch: 0.2
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Genes (trans-elements):
U-clusterSymbol
Annotation
U032117Nr1h4nuclear receptor subfamily 1, group H, member 4

GO terms:
GO:0004872 receptor activity
GO:0043565 sequence-specific DNA binding
GO:0008206 bile acid metabolic process
GO:0004879 ligand-dependent nuclear receptor activity
GO:0046872 metal ion binding
GO:0008270 zinc ion binding
GO:0003707 steroid hormone receptor activity

Protein domains:
IPR001628 Zinc finger, nuclear hormone receptor-type
IPR000536 Nuclear hormone receptor, ligand-binding, core

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

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