CisView: Mouse (mm9, Jul 2007)
Transcription factor binding site ADD_GCNF

Source: Gu P, LeMenuet D, Chung AC, Mancini M, Wheeler DA, Cooney AJ. 2005. Orphan nuclear receptor GCNF is required for the repression of pluripotency genes during retinoic acid-induced embryonic stem cell differentiation. Mol Cell Biol. 25(19):8507-19.
TF group: SF1       TFBS class: HR = Hormone receptor       Code: 2.1.5
Pattern = AGGTCAAGGTCA (core elements are bold)     Class: SF1     Allowed mismatch: 0.186
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Position weight matrix:
positionACGT
1
8101
2
1081
3
0073
4
0208
5
0901
6
10000
7
10000
8
00100
9
0073
10
1306
11
1711
12
8101

Genes (trans-elements):
U-clusterSymbol
Annotation
U022570Nr6a1nuclear receptor subfamily 6, group A, member 1

GO terms:
GO:0004872 receptor activity
GO:0042803 protein homodimerization activity
GO:0043565 sequence-specific DNA binding
GO:0004879 ligand-dependent nuclear receptor activity
GO:0030154 cell differentiation
GO:0046872 metal ion binding
GO:0007276 gamete generation
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0008270 zinc ion binding
GO:0003707 steroid hormone receptor activity
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis

Protein domains:
IPR001628 Zinc finger, nuclear hormone receptor-type
IPR000536 Nuclear hormone receptor, ligand-binding, core

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

Legend