CisView: Mouse (mm9, Jul 2007)
Transcription factor binding site ADD_KLF

Source: Bina M, Wyss P, Ren W, Szpankowski W, Thomas E, Randhawa R, Reddy S, John PM, Pares-Matos EI, Stein A, Xu H, Lazarus SA. 2004. Exploring the characteristics of sequence elements in proximal promoters of human genes. Genomics. 84:929-40.
TF group: KLF       TFBS class: ZF = Zinc finger       Code: 2.3
Pattern = GGGGTGGGG (used as matrix, core elements are bold)     Class: KLF     Allowed mismatch: 0.2
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Genes (trans-elements):
U-clusterSymbol
Annotation
U088097Klf1Kruppel-like factor 1 (erythroid)
U036114Klf10Kruppel-like factor 10
U035866Klf12Kruppel-like factor 12
U035864Klf12Kruppel-like factor 12
U028669Klf13Kruppel-like factor 13
U007173Klf15Kruppel-like factor 15
U032016Klf16Kruppel-like factor 16
U105663Klf2Kruppel-like factor 2 (lung)
U005621Klf3Kruppel-like factor 3 (basic)
U322728Klf3Kruppel-like factor 3 (basic)
U025080Klf4Kruppel-like factor 4 (gut)
U015915Klf5Kruppel-like factor 5
U014517Klf6Kruppel-like factor 6
U021401Klf7Kruppel-like factor 7 (ubiquitous)
U020339Klf8Kruppel-like factor 8
U043714Klf9Kruppel-like factor 9

GO terms:
GO:0046872 metal ion binding
GO:0008270 zinc ion binding
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0045941 positive regulation of transcription
GO:0004872 receptor activity
GO:0019221 cytokine and chemokine mediated signaling pathway
GO:0015758 glucose transport
GO:0007409 axonogenesis
GO:0043565 sequence-specific DNA binding
GO:0043249 erythrocyte maturation
GO:0031077 post-embryonic camera-type eye development
GO:0007566 embryo implantation
GO:0030154 cell differentiation
GO:0006338 chromatin remodeling
GO:0016564 transcription repressor activity
GO:0019827 stem cell maintenance
GO:0001525 angiogenesis
GO:0009913 epidermal cell differentiation
GO:0045672 positive regulation of osteoclast differentiation
GO:0007212 dopamine receptor signaling pathway
GO:0007411 axon guidance
GO:0045892 negative regulation of transcription, DNA-dependent
GO:0008285 negative regulation of cell proliferation
GO:0048813 dendrite morphogenesis
GO:0030033 microvillus biogenesis
GO:0050847 progesterone receptor signaling pathway
GO:0030282 bone mineralization
GO:0048730 epidermis morphogenesis
GO:0048821 erythrocyte development

Protein domains:
IPR015880 Zinc finger, C2H2-like
IPR007087 Zinc finger, C2H2-type
IPR007796 Herpes virus major outer envelope glycoprotein
IPR010881 Gammaherpesvirus latent membrane
IPR010278 Equine herpesvirus glycoprotein gp2
IPR009701 Special lobe-specific silk SSP160
IPR004998 Herpesvirus transcription activation factor
IPR009299 Gammaherpesvirus capsid
IPR008871 Totivirus coat

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

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