CisView: Mouse (mm9, Jul 2007)
Transcription factor binding site ADD_LXR1

Source: Joseph SB, Laffitte BA, Patel PH, Watson MA, Matsukuma KE, Walczak R, Collins JL, Osborne TF, Tontonoz P. 2002. Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors. J Biol Chem. 277:11019-25.
TF group: LXR       TFBS class: HR = Hormone receptor       Code: 2.1.2
Pattern = RGGTTANNNNMGGTCA (used as matrix, core elements are bold)     Class: LXR     Allowed mismatch: 0.2
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Genes (trans-elements):
U-clusterSymbol
Annotation
U001539Rxraretinoid X receptor alpha
U013319Rararetinoic acid receptor, alpha
U022046Tomm40ltranslocase of outer mitochondrial membrane 40 homolog-like (yeast)
U023018Nr1h3nuclear receptor subfamily 1, group H, member 3
U023925Pex5lperoxisomal biogenesis factor 5-like
U027840Pex5peroxisome biogenesis factor 5
U035259Rarbretinoic acid receptor, beta
U036693Rargretinoic acid receptor, gamma
U043589Rxrbretinoid X receptor beta
U134659Nr1h2nuclear receptor subfamily 1, group H, member 2

GO terms:
GO:0004872 receptor activity
GO:0043565 sequence-specific DNA binding
GO:0004879 ligand-dependent nuclear receptor activity
GO:0046872 metal ion binding
GO:0008270 zinc ion binding
GO:0003707 steroid hormone receptor activity
GO:0055012 ventricular cardiac muscle cell differentiation
GO:0003708 retinoic acid receptor activity
GO:0005496 steroid binding
GO:0044255 cellular lipid metabolic process
GO:0043065 positive regulation of apoptosis
GO:0048048 embryonic eye morphogenesis
GO:0016439 tRNA-pseudouridine synthase activity
GO:0015031 protein transport
GO:0016481 negative regulation of transcription
GO:0060038 cardiac muscle cell proliferation
GO:0001657 ureteric bud development
GO:0001764 neuron migration
GO:0050905 neuromuscular process
GO:0045185 maintenance of protein localization
GO:0006820 anion transport
GO:0030425 dendrite
GO:0004884 ecdysteroid hormone receptor activity
GO:0042391 regulation of membrane potential
GO:0019867 outer membrane
GO:0006811 ion transport
GO:0005741 mitochondrial outer membrane
GO:0008308 voltage-gated anion channel activity
GO:0040018 positive regulation of multicellular organism growth
GO:0005739 mitochondrion
GO:0016563 transcription activator activity
GO:0006635 fatty acid beta-oxidation
GO:0016564 transcription repressor activity
GO:0000268 peroxisome targeting sequence binding
GO:0007507 heart development
GO:0007005 mitochondrion organization and biogenesis
GO:0005777 peroxisome
GO:0048468 cell development
GO:0006625 protein targeting to peroxisome
GO:0007029 endoplasmic reticulum organization and biogenesis
GO:0008299 isoprenoid biosynthetic process
GO:0021895 cerebral cortex neuron differentiation
GO:0007031 peroxisome organization and biogenesis
GO:0007006 mitochondrial membrane organization and biogenesis
GO:0055010 ventricular cardiac muscle morphogenesis
GO:0021795 cerebral cortex cell migration
GO:0000038 very-long-chain fatty acid metabolic process

Protein domains:
IPR001628 Zinc finger, nuclear hormone receptor-type
IPR000536 Nuclear hormone receptor, ligand-binding, core
IPR013026 Tetratricopeptide region
IPR014840 Histone promoter control 2 (HPC2)
IPR006574 SPRY-associated
IPR001925 Porin, eukaryotic type
IPR001440 Tetratricopeptide TPR_1
IPR010820 Protein of unknown function DUF1421
IPR010501 TraB pilus assembly
IPR013638 Fork-head N-terminal
IPR007490 Poxvirus B22R protein
IPR002951 Atrophin
IPR007583 GRASP55/65
IPR004957 Spumavirus gag protein
IPR010881 Gammaherpesvirus latent membrane
IPR000784 Late protein L2
IPR007013 Herpes DNA replication accessory factor
IPR006745 Protein of unknown function DUF605
IPR007625 Herpesvirus UL51 protein
IPR008871 Totivirus coat

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

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