TFBS = ADD

CisView: Mouse (mm9, Jul 2007)

Transcription factor binding site ADD_NANOG

Source: Mitsui K, Tokuzawa Y, Itoh H, Segawa K, Murakami M, Takahashi K, Maruyama M, Maeda M, Yamanaka S. 2003. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 113:631-42.
TF group: NANOG TFBS class: HOX = Homeobox Code: 3.1.1
Pattern = RSCSATTAWS (core elements are bold) Class: NANOG Allowed mismatch: 0.09
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Position weight matrix:

position A C G T
1 34 9 57 0
2 8 49 35 8
3 7 80 8 5
4 0 41 56 3
5 91 0 6 3
6 0 0 0 100
7 0 0 0 100
8 86 0 5 9
9 48 0 24 28
10 5 39 51 5

Genes (trans-elements):

U-cluster Symbol Annotation
U007377 Nanog similar to Nanog homeobox

GO terms:
GO:0009880 embryonic pattern specification
GO:0043565 sequence-specific DNA binding
GO:0009790 embryonic development
GO:0042664 negative regulation of endodermal cell fate specification
GO:0017145 stem cell division
GO:0008406 gonad development
GO:0048863 stem cell differentiation
GO:0007275 multicellular organismal development

Protein domains:
IPR001356 Homeobox

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

position	A	C	G	T
1	34	9	57	0
2	8	49	35	8
3	7	80	8	5
4	0	41	56	3
5	91	0	6	3
6	0	0	0	100
7	0	0	0	100
8	86	0	5	9
9	48	0	24	28
10	5	39	51	5

U-cluster	Symbol	Annotation
U007377	Nanog	similar to Nanog homeobox

Legend