TFBS = ADD_OCT4SOX2

CisView: Mouse (mm9, Jul 2007)

Transcription factor binding site ADD_OCT4SOX2

Source: Loh YH, Wu Q, Chew JL, Vega VB, Zhang W. et al. 2006. The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet. 2006, 38:431-40.
TF group: OCT TFBS class: POU = Octamer (POU) Code: 3.1.2
Pattern = YWTTSTHATGCAAAT (core elements are bold) Class: OCT Allowed mismatch: 0.179
Overlap with other TFBS Open table
GO-annotations for traget genes Open table

Position weight matrix:

position A C G T
1 18 44 2 44
2 58 1 3 46
3 0 2 4 102
4 12 0 3 93
5 12 30 58 8
6 33 2 3 70
7 32 30 10 36
8 96 0 4 8
9 3 1 0 104
10 1 0 96 11
11 4 69 9 26
12 86 2 0 20
13 77 3 21 7
14 98 4 6 0
15 17 16 10 65

Genes (trans-elements):

U-cluster Symbol Annotation
U017906 Pou5f1 POU domain, class 5, transcription factor 1

GO terms:
GO:0043565 sequence-specific DNA binding
GO:0030718 germ-line stem cell maintenance
GO:0045892 negative regulation of transcription, DNA-dependent

Protein domains:
IPR001356 Homeobox
IPR000327 POU-specific

Frequency distribution in CpG-rich and CpG-poor promoters (per 1Mb)

position	A	C	G	T
1	18	44	2	44
2	58	1	3	46
3	0	2	4	102
4	12	0	3	93
5	12	30	58	8
6	33	2	3	70
7	32	30	10	36
8	96	0	4	8
9	3	1	0	104
10	1	0	96	11
11	4	69	9	26
12	86	2	0	20
13	77	3	21	7
14	98	4	6	0
15	17	16	10	65

U-cluster	Symbol	Annotation
U017906	Pou5f1	POU domain, class 5, transcription factor 1

Legend