NIA Mouse Gene Index, mm9

816. U000165
Annotation: zeta-chain (TCR) associated protein kinase     Gene?: Yes     Source: NM_009539    Symbol:  Zap70
Chromosome: chr1   Strand: +    Start: 36818642    End: 36839663
List: Positive strand of chr1 (N=5845)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR008266 - Tyrosine protein kinase, active site
IPR011009 - Protein kinase-like
IPR001245 - Tyrosine protein kinase
IPR012234 - Protein-tyrosine kinase, SYK/ZAP-70
IPR000980 - SH2 motif
IPR000719 - Protein kinase

GO-Ontologies
GO:0007242 - intracellular signaling cascade
GO:0007165 - signal transduction
GO:0045582 - positive regulation of T cell differentiation
GO:0018108 - peptidyl-tyrosine phosphorylation
GO:0004672 - protein kinase activity
GO:0005829 - cytosol
GO:0005737 - cytoplasm
GO:0005524 - ATP binding
GO:0005515 - protein binding
GO:0046641 - positive regulation of alpha-beta T cell proliferation
GO:0000166 - nucleotide binding
GO:0016301 - kinase activity
GO:0045059 - positive thymic T cell selection
GO:0045061 - thymic T cell selection
GO:0004715 - non-membrane spanning protein tyrosine kinase activity
GO:0046777 - protein amino acid autophosphorylation
GO:0004713 - protein-tyrosine kinase activity
GO:0001784 - phosphotyrosine binding
GO:0006468 - protein amino acid phosphorylation
GO:0043366 - beta selection
GO:0050850 - positive regulation of calcium-mediated signaling
GO:0016740 - transferase activity
GO:0050852 - T cell receptor signaling pathway
GO:0046638 - positive regulation of alpha-beta T cell differentiation
GO:0042101 - T cell receptor complex
GO:0045060 - negative thymic T cell selection