NIA Mouse Gene Index, mm9

1417. U001627
Annotation: endoglin     Gene?: Yes     Source: NM_001146348    Symbol:  Eng
Chromosome: chr2   Strand: +    Start: 32502046    End: 32538189
List: Positive strand of chr2 (N=7576)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR001507 - Endoglin/CD105 antigen

GO-Ontologies
GO:0048870 - cell motility
GO:0001937 - negative regulation of endothelial cell proliferation
GO:0017015 - regulation of transforming growth factor beta receptor signaling pathway
GO:0007507 - heart development
GO:0048844 - artery morphogenesis
GO:0005737 - cytoplasm
GO:0007179 - transforming growth factor beta receptor signaling pathway
GO:0010862 - positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0005534 - galactose binding
GO:0005024 - transforming growth factor beta-activated receptor activity
GO:0005624 - membrane fraction
GO:0007155 - cell adhesion
GO:0001570 - vasculogenesis
GO:0016021 - integral to membrane
GO:0003273 - cell migration involved in endocardial cushion formation
GO:0001666 - response to hypoxia
GO:0070483 - detection of hypoxia
GO:0005615 - extracellular space
GO:0001947 - heart looping
GO:0016020 - membrane
GO:0034713 - type I transforming growth factor beta receptor binding
GO:0022617 - extracellular matrix disassembly
GO:0001525 - angiogenesis
GO:0001569 - patterning of blood vessels
GO:0050431 - transforming growth factor beta binding
GO:0006355 - regulation of transcription, DNA-dependent
GO:0060326 - cell chemotaxis
GO:0005539 - glycosaminoglycan binding
GO:0030513 - positive regulation of BMP signaling pathway
GO:0031953 - negative regulation of protein autophosphorylation
GO:0005488 - binding
GO:0022009 - central nervous system vasculogenesis
GO:0009986 - cell surface
GO:0048845 - venous blood vessel morphogenesis
GO:0005072 - transforming growth factor beta receptor, cytoplasmic mediator activity
GO:0045766 - positive regulation of angiogenesis
GO:0072563 - endothelial microparticle
GO:0005114 - type II transforming growth factor beta receptor binding
GO:0051001 - negative regulation of nitric-oxide synthase activity
GO:0048745 - smooth muscle tissue development
GO:0042803 - protein homodimerization activity
GO:0009897 - external side of plasma membrane
GO:0042060 - wound healing
GO:0000122 - negative regulation of transcription from RNA polymerase II promoter
GO:0005634 - nucleus
GO:0001934 - positive regulation of protein phosphorylation
GO:0003084 - positive regulation of systemic arterial blood pressure
GO:0045944 - positive regulation of transcription from RNA polymerase II promoter
GO:0060394 - negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0016477 - cell migration