NIA Mouse Gene Index, mm9

613. U003127
Annotation: phosphatidylinositol 3-kinase, catalytic, alpha polypeptide     Gene?: Yes     Source: NM_008839    Symbol:  Pik3ca
Chromosome: chr3   Strand: +    Start: 32296531    End: 32367416
List: Positive strand of chr3 (N=4703)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR000341 - Phosphoinositide 3-kinase, ras-binding
IPR003113 - Phosphatidylinositol 3-kinase, p85-binding
IPR011009 - Protein kinase-like
IPR002420 - Phosphoinositide 3-kinase, C2
IPR000403 - Phosphatidylinositol 3- and 4-kinase, catalytic
IPR008973 - C2 calcium/lipid-binding region, CaLB
IPR001263 - Phosphoinositide 3-kinase accessory region PIK

GO-Ontologies
GO:0043491 - protein kinase B signaling cascade
GO:0007165 - signal transduction
GO:0043066 - negative regulation of apoptosis
GO:0005942 - phosphoinositide 3-kinase complex
GO:0016773 - phosphotransferase activity, alcohol group as acceptor
GO:0040014 - regulation of multicellular organism growth
GO:0006916 - anti-apoptosis
GO:0004428 - inositol or phosphatidylinositol kinase activity
GO:0030027 - lamellipodium
GO:0043560 - insulin receptor substrate binding
GO:0016301 - kinase activity
GO:0048015 - phosphoinositide-mediated signaling
GO:0046934 - phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0016303 - 1-phosphatidylinositol-3-kinase activity
GO:0046854 - phosphoinositide phosphorylation
GO:0006006 - glucose metabolic process
GO:0006468 - protein amino acid phosphorylation
GO:0016740 - transferase activity